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(psilocybin)","substance_tags":"psilocybin","topic_tags":"Addiction,Chronic Pain,Mechanism of Action,Safety,Toxicity","study_type":"Other"},{"id":3705,"title":"Effects of Psilocybin Microdosing on Cognition, Mood and Quality of Life: A Pilot Study","authors":"Yale University","journal":"ClinicalTrials.gov","publication_date":"2026-06-22","doi":null,"pubmed_id":null,"source_url":"https://clinicaltrials.gov/study/NCT07449351","source_name":"ClinicalTrials.gov","publication_status":"clinical trial","keywords":"Psychedelic Microdosing Effects on Mood, Cognition, Subjective Well-being and MRI, Psliocybin, Placebo, NOT_YET_RECRUITING","substance_tags":"psilocybin","topic_tags":"Depression,Brain Imaging,Mechanism of Action,Aging,Longevity,Microdosing,Wellbeing,Treatment-Resistant Depression,Safety","study_type":"Other"},{"id":3637,"title":"Psilocybin-Assisted Therapy for Prolonged Grief","authors":"University of Virginia","journal":"ClinicalTrials.gov","publication_date":"2026-06-22","doi":null,"pubmed_id":null,"source_url":"https://clinicaltrials.gov/study/NCT06724289","source_name":"ClinicalTrials.gov","publication_status":"clinical trial","keywords":"Prolonged Grief Disorder, Psilocybin 25 mg, Functional Magnetic Resonance Imaging (fMRI), RECRUITING","substance_tags":"psilocybin","topic_tags":"Brain Imaging,Aging,Spirituality,Mystical Experience,Clinical Trial","study_type":"Clinical Trial"},{"id":3650,"title":"Psilocybin-assisted Existential, Attachment and Relational (PEARL) Therapy for Caregivers of Patients With Advanced Cancer: A Phase II Open-Label Trial","authors":"University Health Network, Toronto","journal":"ClinicalTrials.gov","publication_date":"2026-06-22","doi":null,"pubmed_id":null,"source_url":"https://clinicaltrials.gov/study/NCT07048743","source_name":"ClinicalTrials.gov","publication_status":"clinical trial","keywords":"Caregiver Distress, Psilocybin, RECRUITING","substance_tags":"psilocybin","topic_tags":"Depression,Anxiety,End-of-Life Distress,Spirituality,Clinical Trial,Safety","study_type":"Clinical Trial"},{"id":3574,"title":"Low-Dose Psilocybin Therapy for Palliative Care Patients With Chronic Cancer Pain Requiring Opioids","authors":"Roswell Park Cancer Institute","journal":"ClinicalTrials.gov","publication_date":"2026-06-21","doi":null,"pubmed_id":null,"source_url":"https://clinicaltrials.gov/study/NCT06827054","source_name":"ClinicalTrials.gov","publication_status":"clinical trial","keywords":"Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Functional Magnetic Resonance Imaging, fMRI, Functional MRI, Interview, Psilocybine, CY-39, Indocybin, Psilocybin, Psychotherapy, talk therapy, Questionnaire Administration, NOT_YET_RECRUITING","substance_tags":"psilocybin","topic_tags":"Addiction,End-of-Life 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Hendricks, Sara Lappan, Richard C. Shelton, Adrienne C. Lahti, Karen L. Cropsey, Matthew W. Johnson, Melissa Bradley, Otto Simonsson, Lori L. Davis, Daniel H. Grossman, Cynthia E. 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Osika W, Mosing MA","journal":"Journal of psychopharmacology (Oxford, England)","publication_date":"2026-04-30","doi":"10.1177/02698811261449385","pubmed_id":"42113558","source_url":"https://pubmed.ncbi.nlm.nih.gov/42113558/","source_name":"PubMed","publication_status":"published","keywords":"LSD, migraine, psilocybin, psychedelics, twins","substance_tags":"psilocybin","topic_tags":"Headache / Migraine,Observational Study","study_type":"Observational Study"},{"id":1959,"title":"C29-12 Psilocybin Treatment Could Improve Outcomes for Age-associated Lung Diseases","authors":"L Hecker, J M Kleinhenz, C Coarfa, K Kato","journal":"American Journal of Respiratory and Critical Care Medicine","publication_date":"2026-04-30","doi":"10.1093/ajrccm/aamag162.144","pubmed_id":null,"source_url":"https://doi.org/10.1093/ajrccm/aamag162.144","source_name":"OpenAlex","publication_status":"published","keywords":"Psilocybin, Medicine, Population, Pharmacology, Disease, Hallucinogen, Metabolite, Oxidative 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Phosphodiesterase function and regulation","substance_tags":"psilocybin","topic_tags":"Depression,Pharmacology,Receptor Pharmacology","study_type":"Other"},{"id":114,"title":"Microdosing psilocybin for major depressive disorder: study protocol for a phase II double-blind placebo-controlled randomised partial crossover trial - CORRIGENDUM","authors":"Zeina Beidas, Anya Ragnhildstveit, Adam Blackman, Thomas Anderson, Emily Fewster, Omer A. Syed, Valentyne Sobolenko, Ismail Kaan Kanca, Tatiana Son, Norman Farb, Rotem Petranker","journal":"BJPsych Open","publication_date":"2026-04-30","doi":"10.1192/bjo.2026.12000","pubmed_id":"42125778","source_url":"https://doi.org/10.1192/bjo.2026.12000","source_name":"OpenAlex","publication_status":"published","keywords":"Psilocybin, Medicine, Protocol (science), Crossover study, Pharmacology, Phase (matter), Clinical trial, Depression (economics), Phases of clinical research, Protocol design, Depressive symptoms, Internal medicine, Psychedelics and Drug Studies, Pain Management and Placebo Effect, Paranormal Experiences and Beliefs","substance_tags":"psilocybin","topic_tags":"Depression,Chronic Pain,Pharmacology,Microdosing,Clinical Trial","study_type":"Clinical Trial"},{"id":1964,"title":"PDE4B Inhibition and Psilocybin as Promising Approaches for Treating Methamphetamine Use Disorder: Preclinical Evidence From Rat Models (Abstract ID: 232554)","authors":"Sean Hayduk, Amy Stringer, Satoria Zagorski, Sara Jane Ward","journal":"Journal of Pharmacology and Experimental Therapeutics","publication_date":"2026-04-30","doi":"10.1016/j.jpet.2026.104282","pubmed_id":null,"source_url":"https://doi.org/10.1016/j.jpet.2026.104282","source_name":"OpenAlex","publication_status":"published","keywords":"Psilocybin, Rat model, Methamphetamine, Pharmacology, Medicine, Hallucinogen, Neuroscience, Drug, Animal model, Anhedonia, Psychedelics and Drug Studies, Phosphodiesterase function and regulation, Neurotransmitter Receptor Influence on Behavior","substance_tags":"psilocybin","topic_tags":"Pharmacology,Receptor Pharmacology,Animal Study","study_type":"Animal Study"},{"id":1956,"title":"Preclinical evaluation of psilocybin and related compounds: Inhibition of cytochrome P450 isoforms","authors":"","journal":"RevSALUS - Revista Científica da Rede Académica das Ciências da Saúde da Lusofonia","publication_date":"2026-04-30","doi":"10.51126/revsalus.v8isupii.46635","pubmed_id":null,"source_url":"https://doi.org/10.51126/revsalus.v8isupii.46635","source_name":"OpenAlex","publication_status":"published","keywords":"Psilocybin, Chemistry, Gene isoform, Cytochrome P450, Pharmacology, Biochemistry, Focus (optics), Cell biology, Enzyme, Plasma protein binding, Biology, Psychedelics and Drug Studies, Forensic Toxicology and Drug Analysis, Cannabis and Cannabinoid Research","substance_tags":"psilocybin","topic_tags":"Pharmacology,Animal Study,Toxicity","study_type":"Animal Study"},{"id":147,"title":"Predictors of therapeutic response to psychedelic-assisted therapy: A systematic review.","authors":"Viljoen G, Walter H, Bendau A, Koslowski M, Betzler F","journal":"Journal of psychopharmacology (Oxford, England)","publication_date":"2026-04-30","doi":"10.1177/02698811251389581","pubmed_id":"41388888","source_url":"https://pubmed.ncbi.nlm.nih.gov/41388888/","source_name":"PubMed","publication_status":"published","keywords":"addictive disorders, depression, psilocybin, psychedelics, psychiatric disorders","substance_tags":"psilocybin","topic_tags":"Depression,Anxiety,PTSD,OCD,End-of-Life Distress,Mystical Experience,Systematic Review,Review Article","study_type":"Systematic Review"},{"id":1958,"title":"Prevalence and Correlates of Past-Year Psilocybin Use in the U.S., 2024, USA","authors":"R Andrew Yockey, Amber Amis, Elise Devier, Aminul Apu, Rachel Hoopsick","journal":"AJPM Focus","publication_date":"2026-04-30","doi":"10.1016/j.focus.2026.100518","pubmed_id":null,"source_url":"https://doi.org/10.1016/j.focus.2026.100518","source_name":"OpenAlex","publication_status":"published","keywords":"Psilocybin, Public health, Harm, Population, Odds, Medicine, Environmental health, Psychology, Substance use, Demography, Psychiatry, Gerontology, Epidemiology, Harm reduction, Descriptive statistics, Hallucinogen, Ethnic group, Population health, Mental health, National Health Interview Survey, National Health and Nutrition Examination Survey, Survey sampling, Telephone survey, Health care, Young adult, Behavioral Risk Factor Surveillance System, Psychedelics and Drug Studies, Forensic Toxicology and Drug Analysis, Cannabis and Cannabinoid Research","substance_tags":"psilocybin","topic_tags":"Addiction,Observational Study,Adolescents,Safety,Toxicity","study_type":"Observational Study"},{"id":1967,"title":"Prohedonic Effects of Psilocybin (COMP360) in a Touchscreen-Based Rodent Probabilistic Reward Task (Abstract ID: 227883)","authors":"Kayleigh LaMalfa, Diego A. 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TMS, ACTIVE_NOT_RECRUITING","substance_tags":"psilocybin","topic_tags":"Brain Imaging,Aging,Healthy Volunteers","study_type":"Other"},{"id":36,"title":"Psilocybin restores behavioral and neuroplastic deficits induced by chronic stress in rats","authors":"Agnieszka Bysiek, Izabela Szpręgiel, Adam Wojtas, Marzena Maćkowiak, Agnieszka Wawrzczak-Bargieła, Monika Leśkiewicz, Ewa Trojan, Katarzyna Kamińska, Weronika Kumorek, Wiktor Bilecki, K Golembiowska","journal":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","publication_date":"2026-04-18","doi":"10.1016/j.pnpbp.2026.111710","pubmed_id":"42009274","source_url":"https://doi.org/10.1016/j.pnpbp.2026.111710","source_name":"OpenAlex","publication_status":"published","keywords":"Psilocybin, Anhedonia, Neuroscience, Hippocampal formation, Hippocampus, Brain-derived neurotrophic factor, Neuroplasticity, Anxiolytic, Antidepressant, Psychology, Neurotrophic factors, Hallucinogen, Endocrinology, Internal medicine, Medicine, Neurogenesis, Limbic system, Long-term potentiation, Pyramidal cell, Neurotrophin, Dentate gyrus, Prefrontal cortex, Open field, Psychedelics and Drug Studies, Neurotransmitter Receptor Influence on Behavior, Forensic Toxicology and Drug Analysis","substance_tags":"psilocybin","topic_tags":"Neuroplasticity,Neurogenesis,Receptor Pharmacology,Toxicity","study_type":"Other"},{"id":4039,"title":"Impact of psilocybin and Psilocybe cubensis extract on gut microbiota in Wistar Han rats","authors":"Francisco Sacadura, Cláudia Marques, Andreia Machado Brito-da-Costa, Mariana Carvalho, Helena Carmo, Ricardo Jorge Dinis-Oliveira, Áurea Madureira-Carvalho, Diana Dias da Silva","journal":"Science Letters","publication_date":"2026-04-16","doi":"10.48797/sl.2026.492","pubmed_id":null,"source_url":"https://doi.org/10.48797/sl.2026.492","source_name":"OpenAlex","publication_status":"published","keywords":"Psilocybin, Biology, Gut flora, Amplicon sequencing, Mushroom, Feces, Pharmacology, Ribosomal RNA, 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Senra, Ricardo Jorge Dinis-Oliveira, Carlos J. A. Ribeiro","journal":"Science Letters","publication_date":"2026-04-16","doi":"10.48797/sl.2026.498","pubmed_id":null,"source_url":"https://doi.org/10.48797/sl.2026.498","source_name":"OpenAlex","publication_status":"published","keywords":"Psilocybin, Chromatography, Chemistry, Mushroom, Extraction (chemistry), Tryptamine, Maceration (sewage), Tryptamines, Pentachlorophenol, Thin-layer chromatography, Solid phase extraction, Column chromatography, Tannin, Gas chromatography, Astringent, Cleanser, Pulp (tooth), Solvent extraction, Mephedrone, Psychedelics and Drug Studies, Forensic Toxicology and Drug Analysis, Silymarin and Mushroom Poisoning","substance_tags":"psilocybin,psilocin","topic_tags":"Toxicity","study_type":"Clinical Trial"},{"id":4035,"title":"Neural Entropy and Cognitive Flexibility: A Research Agenda for Psilocybin-Assisted Therapy [FUTURE DIRECTIONS v1.0]","authors":"Juan Moisés de la Serna de la Serna","journal":"Zenodo (CERN European Organization for Nuclear Research)","publication_date":"2026-04-16","doi":"10.5281/zenodo.19620938","pubmed_id":null,"source_url":"https://doi.org/10.5281/zenodo.19620938","source_name":"OpenAlex","publication_status":"published","keywords":"Cognition, Entropy (arrow of time), Artificial intelligence, Psychology, Computer science, Artificial neural network, Cognitive science, Correlation, Cognitive psychology, Machine learning, Cognitive systems, Neural system, Cognitive computing, Psychedelics and Drug Studies, Pain Management and Placebo Effect, Paranormal Experiences and Beliefs","substance_tags":"psilocybin","topic_tags":"Chronic Pain","study_type":"Other"},{"id":4036,"title":"Oregon’s Psilocybin Services: A summary and public health commentary","authors":"Cassidy R. LoParco, Carlton Bone, Annalynn M. Galvin, Matthew E. Rossheim, Carla Berg","journal":"New Prairie Press (Kansas State University)","publication_date":"2026-04-16","doi":null,"pubmed_id":null,"source_url":"https://newprairiepress.org/hbr/vol9/iss1/20","source_name":"OpenAlex","publication_status":"published","keywords":"Psilocybin, Context (archaeology), Facilitator, Hallucinogen, Licensure, Psychology, Psychiatry, Public health, Test (biology), Medicine, Mood, License, Service (business), Health care, Mental health, Nursing, Service provider, Business, Medical education, Addiction, Mescaline, Public relations, Psychedelics and Drug Studies, Forensic Toxicology and Drug Analysis, Religious Studies and Spiritual Practices","substance_tags":"psilocybin","topic_tags":"Addiction,Emotional Processing,Spirituality,Adolescents,Safety,Toxicity","study_type":"Other"},{"id":3630,"title":"Probing the Functional Magnetic Resonance Imaging Response to Psilocybin in Functional Neurological Disorder (PsiFUND)","authors":"King's College London","journal":"ClinicalTrials.gov","publication_date":"2026-04-16","doi":null,"pubmed_id":null,"source_url":"https://clinicaltrials.gov/study/NCT05723276","source_name":"ClinicalTrials.gov","publication_status":"clinical trial","keywords":"Functional Neurological Disorder, Psilocybin, ACTIVE_NOT_RECRUITING","substance_tags":"psilocybin","topic_tags":"Brain Imaging,Default Mode Network,Aging","study_type":"Other"},{"id":4038,"title":"Psilocybin and Psilocybe cubensis extract exhibit divergent behavioural and toxicological effects in rats","authors":"Diana Dias da Silva, Andreia Machado Brito-da-Costa, Francisco Sacadura, Mariana Carvalho, Helena Carmo, Ricardo Jorge Dinis-Oliveira, Áurea Madureira-Carvalho","journal":"Science Letters","publication_date":"2026-04-16","doi":"10.48797/sl.2026.497","pubmed_id":null,"source_url":"https://doi.org/10.48797/sl.2026.497","source_name":"OpenAlex","publication_status":"published","keywords":"Psilocybin, Pharmacology, Lipid peroxidation, Analysis of variance, Peripheral, Chemistry, Medicine, Antioxidant, Placebo, Toxicity, Physiology, Psychology, Oxidative stress, Positive control, Psychedelics and Drug Studies, Forensic Toxicology and Drug Analysis, Chemical synthesis and alkaloids","substance_tags":"psilocybin,psilocin","topic_tags":"Pharmacology,Oxidative Stress,Animal Study,Toxicity","study_type":"Animal Study"},{"id":169,"title":"Psilocybin reshapes cortical inhibition through selective interneuron recruitment","authors":"Davoudian PA, Jiang Q, Knox CA, Savalia NK, Shao L, Wilson J, Weiner AM, Chong CW, Liao C, Nothnagel JD, Sakurai T, Kwan AC.","journal":"bioRxiv","publication_date":"2026-04-16","doi":"10.64898/2026.04.16.718963","pubmed_id":null,"source_url":"https://doi.org/10.64898/2026.04.16.718963","source_name":"bioRxiv","publication_status":"preprint","keywords":"","substance_tags":"psilocybin","topic_tags":"Receptor Pharmacology,Animal Study","study_type":"Animal Study"},{"id":3019,"title":"Psilocybin in Older Adults: Therapeutic Opportunities in Inflammation-Driven Disorders of Aging-From Depression to Neurodegeneration","authors":"Jóźwiak-Bębenista M, Stasiak A, Sienkiewicz M, Kwiatkowski P, Kowalczyk E.","journal":"Preprints.org","publication_date":"2026-04-14","doi":"10.20944/preprints202604.1125.v1","pubmed_id":null,"source_url":"https://doi.org/10.20944/preprints202604.1125.v1","source_name":"Europe PMC","publication_status":"preprint","keywords":"","substance_tags":"psilocybin,psilocin","topic_tags":"Depression,Pharmacology,Mechanism of Action,Receptor Pharmacology,Default Mode Network,Aging,Inflammaging,Review Article,Older Adults,Treatment-Resistant Depression,Safety,Drug Interactions,Inflammation,Immune Function","study_type":"Review Article"},{"id":1969,"title":"Psilocybin use in Puerto Rico: Patterns, motivations, and personality correlates from an online survey","authors":"JC Rodriguez, Yanice Duquesne-Maldonado, Julián M. Hernández Torres, Istoni Da'Luz Sant'Ana, Cruz M. Nazario","journal":"Journal of Psychedelic Studies","publication_date":"2026-04-14","doi":"10.1556/2054.2026.00519","pubmed_id":null,"source_url":"https://doi.org/10.1556/2054.2026.00519","source_name":"OpenAlex","publication_status":"published","keywords":"Psilocybin, Psychology, Clinical psychology, Personality, Population, Big Five personality traits, Openness to experience, Exploratory research, Logistic regression, Hallucinogen, Anxiety, Paraphernalia, Personality Assessment Inventory, Agreeableness, Snowball sampling, Polysubstance dependence, Sample (material), Curiosity, Distress, Computer-assisted web interviewing, Psychiatry, Young adult, Explanatory model, Multinomial logistic regression, Social psychology, Typology, Empathy, Psychedelics and Drug Studies, Forensic Toxicology and Drug Analysis, Pain Management and Placebo Effect","substance_tags":"psilocybin","topic_tags":"Anxiety,Addiction,Chronic Pain,Personality Change,Spirituality,Observational Study,Toxicity","study_type":"Observational Study"},{"id":3117,"title":"Psilocybin’s Kinematic Effect on Manual Dexterity","authors":"Klintefors P, Bhagavan C, Kanaan R, Bryson A, Berlowitz D, Attard Z, Carter O.","journal":"Research Square","publication_date":"2026-04-14","doi":"10.21203/rs.3.rs-9291780/v1","pubmed_id":null,"source_url":"https://doi.org/10.21203/rs.3.rs-9291780/v1","source_name":"Europe PMC","publication_status":"preprint","keywords":"","substance_tags":"psilocybin","topic_tags":"Clinical Trial,Review Article,Healthy Volunteers,Safety","study_type":"Clinical Trial"},{"id":172,"title":"A phase 1 study of a second experience with Group Retreat Psilocybin Therapy for partial responders after a first experience","authors":"Anthony L. Back, Bonnie A. McGregor, Leslie L. Thorn, Kalin Harvey, Dianna Blom, George Callan, John Guy, Sameet Kumar, Rob Hershberg, Melissa Layer, Jackie Levin, Susanna Myers, Juliana Perez, Kathy Salmonson, Peter Thompson, Joseph Whinney","journal":"Frontiers in Public Health","publication_date":"2026-04-13","doi":"10.3389/fpubh.2026.1810904","pubmed_id":"42058096","source_url":"https://doi.org/10.3389/fpubh.2026.1810904","source_name":"OpenAlex","publication_status":"published","keywords":"Psilocybin, Adverse effect, Nausea, Medicine, Anxiety, Dosing, Depression (economics), Psychiatry, Antidepressant, Hallucinogen, Placebo, Clinical trial, Partial hospitalization, Pharmacotherapy, Exposure therapy, Psychology, Internal medicine, Clinical psychology, Psychological intervention, Relapse prevention, Anesthesia, Physical therapy, Major depressive disorder, Partial agonist, Mental health, Tolerability, Psychedelics and Drug Studies, Forensic Toxicology and Drug Analysis, Pain Management and Placebo Effect","substance_tags":"psilocybin","topic_tags":"Depression,Anxiety,Chronic Pain,Mystical Experience,Clinical Trial,Cancer Patients,Safety,Toxicity","study_type":"Clinical Trial"},{"id":173,"title":"Effects of a single dose of psilocybin on diet-induced weight loss in obese mice.","authors":"Keenan RJ, Haque RT, Jin X, Mustafa T, Homman-Ludiye J, Elysee K, Wee ZS, Simonds SE, Foldi CJ, Cowley MA.","journal":null,"publication_date":"2026-04-13","doi":"10.1038/s41398-026-03995-7","pubmed_id":"41980923","source_url":"https://doi.org/10.1038/s41398-026-03995-7","source_name":"Europe PMC","publication_status":"published","keywords":"Animals, Mice, Inbred C57BL, Mice, Mice, Obese, Obesity, Body Weight, Weight Loss, Hallucinogens, Energy Metabolism, Eating, Male, Diet, High-Fat, Psilocybin","substance_tags":"psilocybin","topic_tags":"Neuroplasticity,Pharmacology,Mechanism of Action,Animal Study","study_type":"Animal Study"},{"id":3578,"title":"CAPSI - Cancer Related Major Depression Treated With a Single Dose of Psilocybin: A Multicenter Randomized Placebo Controlled Double Blind Clinical Trial","authors":"Section for Affective Disorders; Northern Stockholm Psychiatry","journal":"ClinicalTrials.gov","publication_date":"2026-04-12","doi":null,"pubmed_id":null,"source_url":"https://clinicaltrials.gov/study/NCT06319378","source_name":"ClinicalTrials.gov","publication_status":"clinical trial","keywords":"MDD, psilocybin 25 mg sod, psilocybin 1 mg sod, RECRUITING","substance_tags":"psilocybin","topic_tags":"Depression,Clinical Trial","study_type":"Clinical Trial"},{"id":3015,"title":"Psilocybin acutely reduces low-frequency BOLD power and frequency-specific connectivity","authors":"Olsen AS, Larsen K, McCulloch DE, Ganz M, Madsen MK, Ozenne B, Knudsen GM, Rehman Nu, Fisher PM.","journal":"bioRxiv","publication_date":"2026-04-12","doi":"10.64898/2026.04.09.717379","pubmed_id":null,"source_url":"https://doi.org/10.64898/2026.04.09.717379","source_name":"bioRxiv","publication_status":"preprint","keywords":"","substance_tags":"psilocybin,psilocin","topic_tags":"Brain Imaging,Healthy Volunteers","study_type":"Other"},{"id":1970,"title":"Psilocybin for Treatment of Prolonged Grief Disorder: An Open-Label Feasibility Study Protocol","authors":"J. Morgan Penberthy, Fatma Wise, Nicholas P. Cherup, Evaline Mitchell, Madeline Burns, Oluwafunmilayo Akinlade, David Chung, Harshit Parmar, Jonathan Singer","journal":"Psychoactives","publication_date":"2026-04-12","doi":"10.3390/psychoactives5020012","pubmed_id":null,"source_url":"https://doi.org/10.3390/psychoactives5020012","source_name":"OpenAlex","publication_status":"published","keywords":"Psilocybin, Grief, Psychotherapist, Protocol (science), Psychology, Clinical psychology, Medicine, Psychiatry, Complicated grief, Randomized controlled trial, Clinical trial, Cognition, Openness to experience, Exposure therapy, Research design, Single-subject design, Depression (economics), Qualitative research, MEDLINE, Major depressive disorder, Psychedelics and Drug Studies, Paranormal Experiences and Beliefs, Pain Management and Placebo Effect","substance_tags":"psilocybin","topic_tags":"Depression,Chronic Pain,Brain Imaging,Clinical Trial,Randomized Controlled Trial,Safety","study_type":"Randomized Controlled Trial"},{"id":2979,"title":"Observing the mind under psychedelics: conceptual metaphors used following four once-weekly macrodoses of psilocybin","authors":"Eric Rundquist, Diego Nicolás Monasterio López, Juan Jonathan Oyarzo Alvarado, Robin Carhart-Harris, Lorenzo Pasquini, Erin Vinson, Manesh Girn, Avery Ostrand, Kate Allison, Hannes Kettner, Catriona S. Miller, Sydney Griffith, Adam Gazzaley, Andrea Rosati, Jennifer Mitchell","journal":"Philosophical Psychology","publication_date":"2026-04-09","doi":"10.1080/09515089.2026.2657452","pubmed_id":null,"source_url":"https://doi.org/10.1080/09515089.2026.2657452","source_name":"OpenAlex","publication_status":"published","keywords":"Psilocybin, Psychology, Cognitive science, Cognitive psychology, Epistemology, Cognition, Hallucinogen, Metaphor, Psychoanalysis, Conceptual metaphor, Object (grammar), Experimental psychology, Meaning (existential), Psychedelics and Drug Studies, Paranormal Experiences and Beliefs, Pain Management and Placebo Effect","substance_tags":"psilocybin","topic_tags":"Chronic Pain,Brain Imaging,Aging,Healthy Volunteers","study_type":"Other"},{"id":175,"title":"Sex-specific increased reactivity of the PVT and prolonged PVT→CeA circuit engagement following psilocin administration","authors":"D. P. Effinger, J. L. Hoffman, Sema G. Quadir, C. S. Rollison, D. Toedt, M. 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Lynn Wang, Ke Xia, Jia-Bin Wu, Danhao Zheng, Aoling Cai, Haitao Yan, Ruibin Su","journal":"Frontiers in Neuroscience","publication_date":"2026-02-03","doi":"10.3389/fnins.2026.1593703","pubmed_id":"41716660","source_url":"https://doi.org/10.3389/fnins.2026.1593703","source_name":"OpenAlex","publication_status":"published","keywords":"Retrosplenial cortex, Neuroscience, Cingulate cortex, Functional magnetic resonance imaging, Cortex (anatomy), Posterior cingulate, Cerebral cortex, Hippocampal formation, Anterior cingulate cortex, Chemistry, Psychology, Premovement neuronal activity, Hippocampus, Infralimbic cortex, Hallucinogen, Limbic system, Brain mapping, Central nervous system, Amygdala, Human brain, Resting state fMRI, Perirhinal cortex, Posterior parietal cortex, Entorhinal cortex, Medicine, Pharmacology, Psychedelics and Drug Studies, Neurotransmitter Receptor Influence on Behavior, Functional Brain Connectivity Studies","substance_tags":"psilocybin,psilocin","topic_tags":"Depression,Brain Imaging,Pharmacology,Mechanism of Action,Receptor Pharmacology,Aging,Clinical Trial,Animal Study","study_type":"Clinical Trial"},{"id":281,"title":"Retraction: Acute psilocybin increased cortical activities in rats","authors":"Frontiers Editorial Office","journal":"Frontiers in Neuroscience","publication_date":"2026-02-03","doi":"10.3389/fnins.2026.1787833","pubmed_id":"41716656","source_url":"https://doi.org/10.3389/fnins.2026.1787833","source_name":"OpenAlex","publication_status":"published","keywords":"Psilocybin, Medicine, Neuroscience, Pharmacology, Hallucinogen, Internal medicine, Endocrinology, Chemistry, Anesthesia, Central nervous system, Psychedelics and Drug Studies, Forensic Toxicology and Drug Analysis, Paranormal Experiences and Beliefs","substance_tags":"psilocybin","topic_tags":"Pharmacology,Toxicity","study_type":"Other"},{"id":1984,"title":"Computational Analysis of Psilocybin Effects on Three-Choice Touchscreen Reversal Learning in Rats: A Pilot Study","authors":"Anton T. 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Blackmore, Mikael Palner","journal":"Psychedelic Medicine","publication_date":"2026-02-02","doi":"10.1177/28314425251386879","pubmed_id":null,"source_url":"https://doi.org/10.1177/28314425251386879","source_name":"OpenAlex","publication_status":"published","keywords":"Psilocybin, Psychology, Touchscreen, Cognition, Cognitive psychology, Cognitive flexibility, Serotonergic, Hallucinogen, Audiology, Flexibility (engineering), Neuroscience, Discrimination learning, Developmental psychology, Visual perception, Associative learning, Placebo, Modular design, Learning effect, Artifact (error), Crossover study, Psychedelics and Drug Studies, Pain Management and Placebo Effect, Forensic Toxicology and Drug Analysis","substance_tags":"psilocybin","topic_tags":"Chronic Pain,Toxicity,Drug Interactions","study_type":"Other"},{"id":1985,"title":"Psilocybin exerts differential effects on social behavior and inflammation in mice in contexts of activity-based anorexia","authors":"Sheida Shadani, Erika Greaves, Zane B. 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Heinzerling","journal":"Psychedelic Medicine","publication_date":"2025-12-25","doi":"10.1177/28314425251387655","pubmed_id":null,"source_url":"https://doi.org/10.1177/28314425251387655","source_name":"OpenAlex","publication_status":"published","keywords":"Social connectedness, Psychology, Feeling, Clinical psychology, Intervention (counseling), Affect (linguistics), Psychotherapist, Mental health, Alcohol use disorder, Psilocybin, Major depressive disorder, Anhedonia, Social isolation, Session (web analytics), Randomized controlled trial, Social psychology, Peer group, Scale (ratio), Social relation, Psychological intervention, Developmental psychology, Psychiatry, Psychedelics and Drug Studies, Forensic Toxicology and Drug Analysis, Paranormal Experiences and Beliefs","substance_tags":"psilocybin","topic_tags":"Depression,Addiction,Mechanism of Action,Wellbeing,Randomized Controlled Trial,Toxicity","study_type":"Randomized Controlled Trial"},{"id":3043,"title":"Psilocybin decreases reward-seeking behavior accompanied by increased activity of parvalbumin neurons with perineuronal nets in the medial prefrontal cortex","authors":"Houff J, Williams A, Allen O, Gisabella B, Pantazopoulos H, Del Arco A.","journal":"bioRxiv","publication_date":"2025-12-25","doi":"10.64898/2025.12.22.696123","pubmed_id":null,"source_url":"https://doi.org/10.64898/2025.12.22.696123","source_name":"bioRxiv","publication_status":"preprint","keywords":"","substance_tags":"psilocybin","topic_tags":"Addiction,Receptor Pharmacology,Biomarkers,Clinical Trial","study_type":"Clinical Trial"},{"id":145,"title":"The 3D-ASCr scale: A revalidation of the core dimensions of the Altered States of Consciousness Rating Scale 5D(11)-ASC for psychedelic research.","authors":"Stocker K, Hartmann M, Schmid Y, Vogt SB, Becker AM, Ley L, Straumann I, Arikci D, Klaiber A, Erne L, Vizeli P, Holze F, Liechti ME.","journal":null,"publication_date":"2025-12-25","doi":"10.1177/02698811251397328","pubmed_id":"41451514","source_url":"https://doi.org/10.1177/02698811251397328","source_name":"Europe PMC","publication_status":"published","keywords":"","substance_tags":"psilocybin","topic_tags":"Anxiety,Consciousness,Healthy Volunteers","study_type":"Clinical Trial"},{"id":4191,"title":"Evolution and horizontal transfer of the psilocybin biosynthetic gene cluster drive the diversification of magic mushrooms","authors":"Fei Liu, Jiaxin Li, Wen-Qiang Yang, Mao-Qiang He, Bin Cao, Qi Wu, R. Cheewangkoon, Rui-Lin Zhao","journal":"Mycosphere","publication_date":"2025-12-24","doi":"10.5943/mycosphere/16/1/28","pubmed_id":null,"source_url":"https://doi.org/10.5943/mycosphere/16/1/28","source_name":"OpenAlex","publication_status":"published","keywords":"Biology, Psilocybin, Horizontal gene transfer, Gene duplication, Genome, Gene, Evolutionary biology, Gene cluster, Genetics, Genomics, Transcriptome, Multicellular organism, Comparative genomics, Mycelium, Gene family, Phylogenetics, Lineage (genetic), Invertebrate, Diversification (marketing strategy), Convergent evolution, Ecology, Hox gene, Botany, Agaricales, Genome evolution, Psychedelics and Drug Studies, Silymarin and Mushroom Poisoning, Fungal Biology and Applications","substance_tags":"psilocybin","topic_tags":"Genomics,Transcriptomics","study_type":"Other"},{"id":3701,"title":"The Safety and Efficacy of Psilocybin in Patients With Treatment-resistant Depression and Chronic Suicidal Ideation","authors":"Sheppard Pratt Health System","journal":"ClinicalTrials.gov","publication_date":"2025-12-23","doi":null,"pubmed_id":null,"source_url":"https://clinicaltrials.gov/study/NCT05220410","source_name":"ClinicalTrials.gov","publication_status":"clinical trial","keywords":"Treatment Resistant Depression, Suicidal Ideation, Psilocybin, COMPLETED","substance_tags":"psilocybin","topic_tags":"Depression,Treatment-Resistant Depression,Safety","study_type":"Other"},{"id":3055,"title":"A Randomised, Triple-Blind, Dose-Finding Study of the Impact of Psilocybin on Motor Function in Healthy Participants","authors":"Bhagavan C, Carter O, Nielsen G, Berlowitz D, Issak S, Braat S, Zaloumis S, Attard Z, Oliver G, Mayne D, Rucker J, Butler M, Dandash O, Bryson A, Kanaan RA.","journal":"medRxiv","publication_date":"2025-12-22","doi":"10.64898/2025.12.22.25342874","pubmed_id":null,"source_url":"https://doi.org/10.64898/2025.12.22.25342874","source_name":"medRxiv","publication_status":"preprint","keywords":"","substance_tags":"psilocybin","topic_tags":"Headache / Migraine,Consciousness,Clinical Trial,Review Article,Healthy Volunteers,Safety,Adverse Events","study_type":"Clinical Trial"},{"id":3506,"title":"An Open Label Study of Single-Dose Psilocybin for Major Depressive Disorder With Co-occurring Borderline Personality Disorder","authors":"University of Chicago","journal":"ClinicalTrials.gov","publication_date":"2025-12-22","doi":null,"pubmed_id":null,"source_url":"https://clinicaltrials.gov/study/NCT05399498","source_name":"ClinicalTrials.gov","publication_status":"clinical trial","keywords":"Borderline Personality Disorder, Major Depressive Disorder, Psilocybin, COMPLETED","substance_tags":"psilocybin","topic_tags":"Depression,Personality Change,Safety","study_type":"Other"},{"id":1990,"title":"Group Retreat Psilocybin Therapy for People with Metastatic Cancer with Anxiety and Depression: A Rite of Passage Facilitation Model for a Phase 1/2 Study","authors":"Anthony L. 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Hutchison, Jake F. Hooper, Hollis C. 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Williams, David Castle, Susan L. 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Serotonin and dopamine system interactions may underlie the therapeutic potential of psilocybin for anorexia nervosa","authors":"McCoy K, Reed F, Conn K, Foldi CJ.","journal":null,"publication_date":"2025-08-31","doi":null,"pubmed_id":null,"source_url":"https://europepmc.org/article/AGR/IND609297819","source_name":"Europe PMC","publication_status":"published","keywords":"","substance_tags":"psilocybin","topic_tags":"Eating Disorders,End-of-Life Distress,Neuroplasticity,Brain Imaging,Mechanism of Action,Receptor Pharmacology,Aging,Animal Study,Drug Interactions","study_type":"Other"},{"id":4308,"title":"We may know why psilocybin helps treat mental health conditions","authors":"Chris Simms","journal":"The New Scientist","publication_date":"2025-08-31","doi":"10.1016/s0262-4079(25)01446-0","pubmed_id":null,"source_url":"https://doi.org/10.1016/s0262-4079(25)01446-0","source_name":"OpenAlex","publication_status":"published","keywords":"Psilocybin, Mental health, Psychiatry, Psychology, Medicine, Mental health care, Psychotherapist, Depression (economics), MEDLINE, Mental illness, Schizophrenia (object-oriented programming), Health care, Anxiety, Psychedelics and Drug Studies, Mental Health and Psychiatry, Paranormal Experiences and Beliefs","substance_tags":"psilocybin","topic_tags":"Depression,Anxiety","study_type":"Other"},{"id":542,"title":"“Wood-lover paralysis”: Describing a toxidrome with symptoms of weakness caused by some lignicolous “wood-loving” Psilocybe mushrooms","authors":"Beck SA, Barlow C, Engel L, Barratt MJ.","journal":null,"publication_date":"2025-08-31","doi":null,"pubmed_id":null,"source_url":"https://europepmc.org/article/AGR/IND609301091","source_name":"Europe PMC","publication_status":"published","keywords":"","substance_tags":"psilocybin","topic_tags":"Observational Study","study_type":"Observational Study"},{"id":490,"title":"US Poison Center Encounters for Psilocybin-Related Exposures: 2013-2022","authors":"Juan Carlos C. 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Higgins, Cam MacMillan, Inés de Lannoy, Carolyn M. 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Ekwudo, Carey Wilson, Carolina Gubert, Anthony J. 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Strickland, Roland R. Griffiths, Albert Garcia-Romeu","journal":"Psychedelic Medicine","publication_date":"2023-08-29","doi":"10.1089/psymed.2023.0035","pubmed_id":"38152462","source_url":"https://doi.org/10.1089/psymed.2023.0035","source_name":"OpenAlex","publication_status":"published","keywords":"Psilocybin, Hallucinogen, Dextromethorphan, Psychology, Psychotherapist, Clinical psychology, Psychiatry, Psychedelics and Drug Studies, Pain Management and Placebo Effect, Paranormal Experiences and Beliefs","substance_tags":"psilocybin","topic_tags":"Chronic Pain,Receptor Pharmacology,Consciousness,Wellbeing,Spirituality,Healthy Volunteers,Safety","study_type":"Other"},{"id":4784,"title":"Pharmacology and Therapeutic Effects of Psilocybin","authors":"Xuehan Du","journal":"Highlights in Science Engineering and Technology","publication_date":"2023-08-28","doi":"10.54097/hset.v65i.11331","pubmed_id":null,"source_url":"http://dx.doi.org/10.54097/hset.v65i.11331","source_name":"OpenAlex","publication_status":"published","keywords":"Psilocybin, Hallucinogen, Lysergic acid diethylamide, Mechanism (biology), Addiction, Pharmacology, Psychology, Mescaline, Psychosis, Psychiatry, Medicine, Serotonin, Internal medicine, Philosophy, Receptor, Epistemology, Psychedelics and Drug Studies, Chemical synthesis and alkaloids, Tryptophan and brain disorders","substance_tags":"psilocybin","topic_tags":"Depression,Anxiety,Addiction,OCD,Pharmacology,Mechanism of Action,Receptor Pharmacology,Adverse Events,Toxicity","study_type":"Other"},{"id":1310,"title":"Development and validation of a sensitive LC-MS-MS method to quantify psilocin in authentic oral fluid samples","authors":"Marilia Santoro Cardoso, Kelly Francisco da Cunha, Izabelly Geraldes Silva, Taís Regina Fiorentin, Eduardo Geraldo de Campos, José Luiz Costa","journal":"Journal of Analytical Toxicology","publication_date":"2023-08-27","doi":"10.1093/jat/bkad064","pubmed_id":"37642343","source_url":"https://doi.org/10.1093/jat/bkad064","source_name":"OpenAlex","publication_status":"published","keywords":"Chromatography, Chemistry, Analyte, Mass spectrometry, Detection limit, Extraction (chemistry), Tandem mass spectrometry, Liquid chromatography–mass spectrometry, Sample preparation, Selected reaction monitoring, Psychedelics and Drug Studies, Forensic Toxicology and Drug Analysis, Neurotransmitter Receptor Influence on Behavior","substance_tags":"psilocybin,psilocin","topic_tags":"Receptor Pharmacology,Toxicity","study_type":"Other"},{"id":3149,"title":"Intravenous psilocybin administration attenuates mechanical hypersensitivity in a rat model of chronic pain","authors":"Kolbman N, Liu T, Guzzo P, Gilligan JP, Mashour GA, Vanini G, Pal D.","journal":"bioRxiv","publication_date":"2023-08-27","doi":"10.1101/2023.08.26.554802","pubmed_id":null,"source_url":"https://doi.org/10.1101/2023.08.26.554802","source_name":"bioRxiv","publication_status":"preprint","keywords":"","substance_tags":"psilocybin","topic_tags":"Chronic Pain,Animal Study","study_type":"Animal Study"},{"id":1042,"title":"Beyond Psilocybin: Reviewing the Therapeutic Potential of Other Serotonergic Psychedelics in Mental and Substance Use Disorders.","authors":"Wong S, Yu AY, Fabiano N, Finkelstein O, Pasricha A, Jones BDM, Rosenblat JD, Blumberger DM, Mulsant BH, Husain MI.","journal":null,"publication_date":"2023-08-23","doi":"10.1080/02791072.2023.2251133","pubmed_id":"37615379","source_url":"https://doi.org/10.1080/02791072.2023.2251133","source_name":"Europe PMC","publication_status":"published","keywords":"Humans, Banisteriopsis, Substance-Related Disorders, N,N-Dimethyltryptamine, Mescaline, Lysergic Acid Diethylamide, Ibogaine, Serotonin Agents, Hallucinogens, Mental Disorders, Psilocybin","substance_tags":"psilocybin","topic_tags":"Anxiety,Addiction,Receptor Pharmacology,Review Article,Safety,Adverse Events","study_type":"Review Article"},{"id":1404,"title":"Psilocybin desynchronizes brain networks","authors":"Siegel JS, Subramanian S, Perry D, Kay B, Gordon E, Laumann T, Reneau R, Gratton C, Horan C, Metcalf N, Chacko R, Schweiger J, Wong D, Bender D, Padawer-Curry J, Raison C, Raichle M, Lenze EJ, Snyder AZ, Dosenbach NU, Nicol G.","journal":"medRxiv","publication_date":"2023-08-23","doi":"10.1101/2023.08.22.23294131","pubmed_id":null,"source_url":"https://doi.org/10.1101/2023.08.22.23294131","source_name":"medRxiv","publication_status":"preprint","keywords":"","substance_tags":"psilocybin","topic_tags":"Neuroplasticity,Default Mode Network","study_type":"Other"},{"id":1405,"title":"Race and ethnicity moderate the associations between lifetime psilocybin use and crime arrests","authors":"Grant Jones, Maha Al-Suwaidi, Franchesca Castro-Ramirez, Taylor C. 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(Psylocibe cubensis).","authors":"Polo-Castellano C, Álvarez JÁ, Palma M, Barbero GF, Ayuso J, Ferreiro-González M.","journal":"Journal of Fungi","publication_date":"2022-06-01","doi":"10.3390/jof8060598","pubmed_id":"35736081","source_url":"https://doi.org/10.3390/jof8060598","source_name":"Europe PMC","publication_status":"published","keywords":"","substance_tags":"psilocybin,psilocin","topic_tags":"General","study_type":"Other"},{"id":1723,"title":"Phosphate moiety in FDA-approved pharmaceutical salts and prodrugs.","authors":"Fulmali A, Bharate SS.","journal":null,"publication_date":"2022-06-01","doi":"10.1002/ddr.21953","pubmed_id":"35656613","source_url":"https://doi.org/10.1002/ddr.21953","source_name":"Europe PMC","publication_status":"published","keywords":"Phosphates, Salts, Pyrrolidinones, Indoles, Leucine, Prodrugs, Solubility","substance_tags":"psilocybin","topic_tags":"Pharmacology,Review Article,Toxicity","study_type":"Review Article"},{"id":4958,"title":"Association of 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Mason, Elisabeth Mischler, Malin V. Uthaug, Kim P. C. Kuypers","journal":"Journal of Psychoactive Drugs","publication_date":"2019-02-25","doi":"10.1080/02791072.2019.1580804","pubmed_id":"30905276","source_url":"https://doi.org/10.1080/02791072.2019.1580804","source_name":"OpenAlex","publication_status":"published","keywords":"Psilocybin, Empathy, Psychology, Clinical psychology, Developmental psychology, Psychotherapist, Hallucinogen, Psychiatry, Psychedelics and Drug Studies, Mental Health Research Topics, Chemical synthesis and alkaloids","substance_tags":"psilocybin","topic_tags":"Depression,Wellbeing,Emotional Processing,Creativity,Drug Interactions","study_type":"Other"},{"id":2359,"title":"Emerging from the dark side: new therapeutic applications of scheduled psychoactive substances.","authors":"James E, Robertshaw TL, Westwell AD","journal":"Future medicinal chemistry","publication_date":"2019-01-31","doi":"10.4155/fmc-2018-0447","pubmed_id":"30763121","source_url":"https://pubmed.ncbi.nlm.nih.gov/30763121/","source_name":"PubMed","publication_status":"published","keywords":"MDMA, harm reduction, healthcare, positive psychology, psilocybin, psychoactive, psychotherapy","substance_tags":"psilocybin","topic_tags":"General","study_type":"Other"},{"id":3946,"title":"The effects of psilocybin microdosing on perception: a double-blind controlled study","authors":"Michiel van Elk, George Fejer, Josephine Marschall, Pascal Lempe","journal":"OSF Preprints (OSF Preprints)","publication_date":"2019-01-30","doi":null,"pubmed_id":null,"source_url":"https://osf.io/cn8z4","source_name":"OpenAlex","publication_status":"published","keywords":"Psilocybin, Double blind, Perception, Psychology, Medicine, Hallucinogen, Placebo, Neuroscience, Psychiatry, Alternative medicine, Pathology, Psychedelics and Drug Studies, Sexuality, Behavior, and Technology, Body Image and Dysmorphia Studies","substance_tags":"psilocybin","topic_tags":"Microdosing","study_type":"Other"},{"id":2042,"title":"Psychedelic effects of psilocybin correlate with serotonin 2A receptor occupancy and plasma psilocin levels","authors":"M. Madsen, Patrick M. Fisher, Daniel Burmester, Agnete Dyssegaard, Dea Siggaard Stenbæk, Sara Kristiansen, Sys Stybe Johansen, Sczabolz Lehel, Kristían Línnet, Claus Svarer, David Erritzøe, Brice Ozenne, Gitte M. Knudsen","journal":"Neuropsychopharmacology","publication_date":"2019-01-25","doi":"10.1038/s41386-019-0324-9","pubmed_id":"30685771","source_url":"https://doi.org/10.1038/s41386-019-0324-9","source_name":"OpenAlex","publication_status":"published","keywords":"Psilocybin, Hallucinogen, Chemistry, Binding potential, Psychology, Internal medicine, Pharmacology, Positron emission tomography, Neuroscience, Medicine, Psychedelics and Drug Studies, Chemical synthesis and alkaloids, Neurotransmitter Receptor Influence on Behavior","substance_tags":"psilocybin,psilocin","topic_tags":"Pharmacology,Receptor Pharmacology","study_type":"Other"},{"id":3315,"title":"Serotonergic Psychedelics LSD & Psilocybin Increase the Fractal Dimension of Cortical Brain Activity in Spatial and Temporal Domains","authors":"Varley T, Carhart-Harris R, Roseman L, Menon DK, Stamatakis E.","journal":"bioRxiv","publication_date":"2019-01-10","doi":"10.1101/517847","pubmed_id":null,"source_url":"https://doi.org/10.1101/517847","source_name":"bioRxiv","publication_status":"preprint","keywords":"","substance_tags":"psilocybin","topic_tags":"Brain Imaging,Consciousness","study_type":"Other"},{"id":2343,"title":"Pharmacological interventions targeting anhedonia in patients with major depressive disorder: A systematic review.","authors":"Cao B, Zhu J, Zuckerman H, Rosenblat JD, Brietzke E, Pan Z, Subramanieapillai M, Park C, Lee Y, McIntyre RS.","journal":null,"publication_date":"2019-01-02","doi":"10.1016/j.pnpbp.2019.01.002","pubmed_id":"30611836","source_url":"https://doi.org/10.1016/j.pnpbp.2019.01.002","source_name":"Europe PMC","publication_status":"published","keywords":"Humans, Antidepressive Agents, Anhedonia, Major Depressive Disorder","substance_tags":"psilocybin","topic_tags":"Depression,Systematic Review,Review Article","study_type":"Systematic Review"},{"id":3732,"title":"Microdosing psychedelics: personality, mental health, and creativity differences in microdosers.","authors":"Anderson T, Petranker R, Rosenbaum D, Weissman CR, Dinh-Williams LA, Hui K, Hapke E, Farb NAS.","journal":null,"publication_date":"2019-01-01","doi":"10.1007/s00213-018-5106-2","pubmed_id":"30604183","source_url":"https://doi.org/10.1007/s00213-018-5106-2","source_name":"Europe PMC","publication_status":"published","keywords":"Humans, Lysergic Acid Diethylamide, Hallucinogens, Depression, Emotions, Anxiety, Personality, Mental Health, Perception, Dose-Response Relationship, Drug, Adult, Female, Male, Creativity, Surveys and Questionnaires, Psilocybin","substance_tags":"psilocybin","topic_tags":"Depression,Anxiety,End-of-Life Distress,Microdosing,Wellbeing,Personality Change,Emotional Processing,Creativity,Observational Study,Safety","study_type":"Observational Study"},{"id":3949,"title":"Effects of psilocybin on functional connectivity measured with fNIRS: Insights from a single-subject pilot study","authors":"Felix Scholkmann, Lisa Holper, Katrin H. 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Psychological","substance_tags":"psilocybin","topic_tags":"Personality Change,Creativity,Spirituality,Mystical Experience,Randomized Controlled Trial","study_type":"Randomized Controlled Trial"},{"id":2609,"title":"Psilocybin-induced deficits in automatic and controlled inhibition are attenuated by ketanserin in healthy human volunteers.","authors":"Quednow BB, Kometer M, Geyer MA, Vollenweider FX.","journal":"Neuropsychopharmacology","publication_date":"2011-09-27","doi":"10.1038/npp.2011.228","pubmed_id":"21956447","source_url":"https://doi.org/10.1038/npp.2011.228","source_name":"Europe PMC","publication_status":"published","keywords":"Humans, Ketanserin, Serotonin Antagonists, Hallucinogens, Acoustic Stimulation, Double-Blind Method, Neuropsychological Tests, Adult, Female, Male, Sensory Gating, Reflex, Startle, Surveys and Questionnaires, Psilocybin, Inhibition, Psychological","substance_tags":"psilocybin,psilocin","topic_tags":"Receptor Pharmacology,Consciousness,Observational 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G Nicholas & Kerry Ogame Social Science","authors":"L. 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SYNTHESIS OF3-(2-(DIALKYLAMINO)ETHYL)- AND3-(2-(CYCLOALKYLAMINO)ETHYL)INDOL-4-OLS","authors":"REPKE D. B., FERGUSON W. J., BATES D. 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Gottlieb","journal":null,"publication_date":"1976-02-28","doi":null,"pubmed_id":null,"source_url":"https://eurekamag.com/pdf/038/038903782.pdf","source_name":"OpenAlex","publication_status":"published","keywords":"Psilocybin, Psychology, Hallucinogen, Psychiatry, Psychedelics and Drug Studies, Religious Studies and Spiritual Practices, Paranormal Experiences and Beliefs","substance_tags":"psilocybin","topic_tags":"Spirituality","study_type":"Other"},{"id":2851,"title":"Drug-induced conditioned suppression: specificity due to drug employed as UCS.","authors":"Cameron OG, Appel JB.","journal":null,"publication_date":"1976-01-31","doi":"10.1016/0091-3057(76)90020-4","pubmed_id":"1265108","source_url":"https://doi.org/10.1016/0091-3057(76)90020-4","source_name":"Europe PMC","publication_status":"published","keywords":"Animals, Rats, Lysergic Acid Diethylamide, Atropine, Atropine Derivatives, Pentobarbital, Conditioning, Classical, Reinforcement Schedule, Male, Psilocybin","substance_tags":"psilocybin","topic_tags":"General","study_type":"Other"},{"id":5511,"title":"Hallucinogenic Mushrooms Including Chemical Hallucinogens: Bufotenin and Psilocybin; a Select Bibliography.","authors":"Sybil H. Bullock","journal":"Defense Technical Information Center (DTIC)","publication_date":"1975-10-31","doi":null,"pubmed_id":null,"source_url":"http://oai.dtic.mil/oai/oai?&amp;verb=getRecord&amp;metadataPrefix=html&amp;identifier=ADA028792","source_name":"OpenAlex","publication_status":"published","keywords":"Psilocybin, Hallucinogen, Art, Psychology, Psychiatry, Psychedelics and Drug Studies, Chemical synthesis and alkaloids, Biochemical Analysis and Sensing Techniques","substance_tags":"psilocybin","topic_tags":"General","study_type":"Other"},{"id":2853,"title":"Comparison of the discriminative stimulus properties of delta9-THC and psilocybin in rats.","authors":"Greenberg I, Kuhn D, Appel JB.","journal":null,"publication_date":"1975-08-31","doi":"10.1016/0091-3057(75)90131-8","pubmed_id":"1208637","source_url":"https://doi.org/10.1016/0091-3057(75)90131-8","source_name":"Europe PMC","publication_status":"published","keywords":"Animals, Rats, Cannabis, Punishment, Time Factors, Extinction, Psychological, Dronabinol, Psilocybin, Discrimination, Psychological","substance_tags":"psilocybin","topic_tags":"General","study_type":"Other"},{"id":2854,"title":"Interactions between lysergic acid diethylamide and dopamine-sensitive adenylate cyclase systems in rat brain.","authors":"Hungen KV, Roberts S, Hill DF.","journal":null,"publication_date":"1975-07-31","doi":"10.1016/0006-8993(75)90876-8","pubmed_id":"238721","source_url":"https://doi.org/10.1016/0006-8993(75)90876-8","source_name":"Europe PMC","publication_status":"published","keywords":"Brain, Hippocampus, Corpus Striatum, Animals, Norepinephrine, Propranolol, Dopamine, Serotonin, Promethazine, Haloperidol, Lysergic Acid Diethylamide, Methysergide, Cyproheptadine, Chlorpromazine, Thioridazine, Trifluoperazine, Hallucinogens, Enzyme Activation, Dose-Response Relationship, Drug, Male, Adenylyl Cyclases","substance_tags":"psilocin","topic_tags":"Receptor Pharmacology,Animal Study,Drug Interactions","study_type":"Animal Study"},{"id":2855,"title":"Therapeutic usefulness of hallucinogenic drugs as a function of their chemical structure.","authors":"Fischer R, Goldman H.","journal":null,"publication_date":"1975-06-30","doi":"10.1055/s-0028-1094457","pubmed_id":"1233520","source_url":"https://doi.org/10.1055/s-0028-1094457","source_name":"Europe PMC","publication_status":"published","keywords":"Brain, Humans, Catecholamines, Mescaline, Lysergic Acid Diethylamide, Naloxone, Hallucinogens, Mental Disorders, Binding Sites, Structure-Activity Relationship, Chemistry, Chemical Phenomena","substance_tags":"psilocybin","topic_tags":"Receptor Pharmacology,Adverse Events","study_type":"Other"},{"id":2856,"title":"Adaptive changes in behavior after repeated administration of various psychoactive drugs.","authors":"Rech RH, Tilson HA, Marquis WJ.","journal":null,"publication_date":"1974-12-31","doi":null,"pubmed_id":"1163377","source_url":"https://europepmc.org/article/MED/1163377","source_name":"Europe PMC","publication_status":"published","keywords":"Animals, Rats, Dextroamphetamine, Hallucinogens, Psychotropic Drugs, Adaptation, Psychological, Behavior, Animal, Motor Activity, Avoidance Learning, Reinforcement Schedule","substance_tags":"psilocybin","topic_tags":"Mechanism of Action,Receptor Pharmacology,Drug Interactions","study_type":"Clinical Trial"},{"id":2857,"title":"Hallucinogenic indoleamines: Preferential action upon presynaptic serotonin receptors.","authors":"Aghajanian GK, Hailgler HJ.","journal":null,"publication_date":"1974-12-31","doi":null,"pubmed_id":"1063421","source_url":"https://europepmc.org/article/MED/1063421","source_name":"Europe PMC","publication_status":"published","keywords":"Synapses, Animals, Rats, N,N-Dimethyltryptamine, Serotonin, Lysergic Acid Diethylamide, Indoles, Bufotenin, Receptors, Drug, Hallucinogens, Male, In Vitro Techniques, Psilocybin","substance_tags":"psilocybin,psilocin","topic_tags":"Neuroplasticity,Receptor Pharmacology,In Vitro Study","study_type":"In Vitro Study"},{"id":5513,"title":"The Psilocybin Mushroom Pandemic","authors":"Steven H. Pollock","journal":"Journal of Psychedelic Drugs","publication_date":"1974-12-31","doi":"10.1080/02791072.1975.10472640","pubmed_id":null,"source_url":"https://doi.org/10.1080/02791072.1975.10472640","source_name":"OpenAlex","publication_status":"published","keywords":"Psilocybin, Mushroom, Pandemic, Coronavirus disease 2019 (COVID-19), Mushroom poisoning, 2019-20 coronavirus outbreak, Medicine, Virology, Hallucinogen, Biology, Pharmacology, Food science, Internal medicine, Infectious disease (medical specialty), Outbreak, Disease, Psychedelics and Drug Studies, Neurotransmitter Receptor Influence on Behavior","substance_tags":"psilocybin","topic_tags":"Pharmacology,Receptor Pharmacology","study_type":"Other"},{"id":2115,"title":"ChemInform Abstract: NEUER ZUGANG ZU PSILOCIN-DERIVATEN","authors":"GERMAIN CLAUDE, BOURDAIS JACQUES","journal":"Chemischer Informationsdienst","publication_date":"1974-12-09","doi":"10.1002/chin.197449273","pubmed_id":null,"source_url":"https://doi.org/10.1002/chin.197449273","source_name":"Crossref","publication_status":"published","keywords":"","substance_tags":"psilocin","topic_tags":"General","study_type":"Other"},{"id":2858,"title":"Hypersensitivity to lysergic acid diethylamide (LSD-25) and psilocybin in essential headache.","authors":"Fanciullacci M, Franchi G, Sicuteri F.","journal":null,"publication_date":"1974-11-30","doi":"10.1007/bf01919685","pubmed_id":"4442544","source_url":"https://doi.org/10.1007/bf01919685","source_name":"Europe PMC","publication_status":"published","keywords":"Blood-Brain Barrier, Brain, Humans, Hallucinations, Headache, Serotonin, Lysergic Acid Diethylamide, Receptors, Drug, Emotions, Brain Chemistry, Structure-Activity Relationship, Dose-Response Relationship, Drug, Adult, Middle Aged, Female, Male, Psilocybin","substance_tags":"psilocybin","topic_tags":"Headache / Migraine,Receptor Pharmacology,Emotional Processing","study_type":"Other"},{"id":5516,"title":"幻覚剤に関する研究-5-Psilocybinの合成(ノ-ト)","authors":"昌子 大野","journal":"衛生試験所報告","publication_date":"1974-10-31","doi":null,"pubmed_id":null,"source_url":"http://ci.nii.ac.jp/naid/40000202990","source_name":"OpenAlex","publication_status":"published","keywords":"Psilocybin, Computer science, Psychology, Hallucinogen, Psychiatry, Military Technology and Strategies, Legal and Regulatory Analysis, Linguistic, Cultural, and Literary Studies","substance_tags":"psilocybin","topic_tags":"General","study_type":"Other"},{"id":5517,"title":"ChemInform Abstract: CRYSTAL STRUCTURES OF THE TEONANACATL HALLUCINOGENS PART1, PSILOCYBIN C12H17N2O4O","authors":"Hans Peter Weber, Trevor J. 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Prediction of response to psilocybin.","authors":"Panton Y, Fischer R.","journal":null,"publication_date":"1973-02-28","doi":"10.1001/archpsyc.1973.01750330106017","pubmed_id":"4688632","source_url":"https://doi.org/10.1001/archpsyc.1973.01750330106017","source_name":"Europe PMC","publication_status":"published","keywords":"Humans, Hallucinations, Pulse, Probability, Emotions, Personality, Sensory Deprivation, Visual Perception, Arousal, Handwriting, Adult, Female, Male, Psilocybin","substance_tags":"psilocybin","topic_tags":"Personality Change,Emotional Processing","study_type":"Other"},{"id":2121,"title":"ChemInform Abstract: SYNTH. DES SCHWEFELANALOGEN VON PSILOCIN UND EINIGEN VERWANDTEN VERBINDUNGEN","authors":"CHAPMAN N. B., SCROWSTON R. M., SUTTON T. M.","journal":"Chemischer Informationsdienst","publication_date":"1973-02-19","doi":"10.1002/chin.197308246","pubmed_id":null,"source_url":"https://doi.org/10.1002/chin.197308246","source_name":"Crossref","publication_status":"published","keywords":"","substance_tags":"psilocin","topic_tags":"General","study_type":"Other"},{"id":2870,"title":"Molecular structures of hallucinogenic substances: lysergic acid diethylamide, psilocybin, and 2,4,5-trimethoxyamphetamine.","authors":"Baker RW, Chothia C, Pauling P, Weber HP.","journal":null,"publication_date":"1972-12-31","doi":"10.1016/s0026-895x(25)13703-6","pubmed_id":"4685449","source_url":"https://doi.org/10.1016/s0026-895x(25)13703-6","source_name":"Europe PMC","publication_status":"published","keywords":"Tryptamines, Amphetamine, Lysergic Acid Diethylamide, Hallucinogens, Crystallography, X-Ray Diffraction, Molecular Conformation, Psilocybin","substance_tags":"psilocybin","topic_tags":"General","study_type":"Other"},{"id":2869,"title":"[Studies on hallucinogens. 3. Synthesis of psilocin (author's transl)].","authors":"Ono M, Shimamine M, Takahashi K.","journal":null,"publication_date":"1972-12-31","doi":null,"pubmed_id":"4800137","source_url":"https://europepmc.org/article/MED/4800137","source_name":"Europe PMC","publication_status":"published","keywords":"Hallucinogens, Spectrophotometry, Infrared, Mass Spectrometry, Psilocybin","substance_tags":"psilocybin,psilocin","topic_tags":"General","study_type":"Other"},{"id":5525,"title":"精神分裂病者の病像とPsilocybin,LSD-25反応に関する精神病理学的研究","authors":"襄 三隅","journal":"Medical Entomology and Zoology","publication_date":"1972-09-30","doi":null,"pubmed_id":null,"source_url":"http://ci.nii.ac.jp/naid/40018016189","source_name":"OpenAlex","publication_status":"published","keywords":"Psilocybin, Hallucinogen, Psychology, Psychiatry, Military Technology and Strategies, Legal and Regulatory Analysis, Linguistic, Cultural, and Literary Studies","substance_tags":"psilocybin","topic_tags":"General","study_type":"Other"},{"id":1943,"title":"Psilocybin.","authors":"Mulkey D.","journal":null,"publication_date":"1972-06-30","doi":null,"pubmed_id":"5039020","source_url":"https://europepmc.org/article/MED/5039020","source_name":"Europe PMC","publication_status":"published","keywords":"Humans, Substance-Related Disorders, Chemistry, Chemical Phenomena, Psilocybin","substance_tags":"psilocybin","topic_tags":"General","study_type":"Other"},{"id":5527,"title":"The effect of bufotenine, melatonin, psilocybin, and related compounds on the 5-hydroxytryptamine excitatory receptors of Helix aspersa neurons","authors":"Robert Walker, G.N. Woodruff","journal":"Comparative and General Pharmacology","publication_date":"1972-02-29","doi":"10.1016/0010-4035(72)90039-0","pubmed_id":null,"source_url":"https://doi.org/10.1016/0010-4035(72)90039-0","source_name":"OpenAlex","publication_status":"published","keywords":"Melatonin, Psilocybin, Receptor, Excitatory postsynaptic potential, Biology, Neuroscience, Chemistry, Hallucinogen, Pharmacology, Biochemistry, Psychedelics and Drug Studies, Neurotransmitter Receptor Influence on Behavior, Nicotinic Acetylcholine Receptors Study","substance_tags":"psilocybin","topic_tags":"Neuroplasticity,Pharmacology,Receptor Pharmacology","study_type":"Other"},{"id":2122,"title":"Synthesis of the sulphur analogue of psilocin and some related compounds","authors":"Chapman N. B., Scrowston R. M., Sutton T. M.","journal":"Journal of the Chemical Society, Perkin Transactions 1","publication_date":"1971-12-31","doi":"10.1039/p19720003011","pubmed_id":null,"source_url":"https://doi.org/10.1039/p19720003011","source_name":"Crossref","publication_status":"published","keywords":"","substance_tags":"psilocin","topic_tags":"General","study_type":"Other"},{"id":2871,"title":"Effects of psilocybin, dimethyltryptamine, mescaline and various lysergic acid derivatives on the EEG and on photically induced epilepsy in the baboon (Papio papio).","authors":"Meldrum BS, Naquet R.","journal":null,"publication_date":"1971-11-30","doi":"10.1016/0013-4694(71)90072-1","pubmed_id":"4111479","source_url":"https://doi.org/10.1016/0013-4694(71)90072-1","source_name":"Europe PMC","publication_status":"published","keywords":"Cerebral Cortex, Animals, Haplorhini, Papio, Epilepsy, Tryptamines, Mescaline, Lysergic Acid Diethylamide, Methysergide, Electroencephalography, Light, Psilocybin","substance_tags":"psilocybin","topic_tags":"Brain Imaging","study_type":"Other"},{"id":2872,"title":"An electroencephalographic analysis of personality-dependent performance under psilocybin.","authors":"Thatcher K, Wiederholt WC, Fischer R.","journal":null,"publication_date":"1971-03-31","doi":"10.1007/bf01965376","pubmed_id":"5129520","source_url":"https://doi.org/10.1007/bf01965376","source_name":"Europe PMC","publication_status":"published","keywords":"Cerebral Cortex, Humans, Electroencephalography, Analysis of Variance, Motor Activity, Personality, Light, Pressure, Handwriting, Adult, Habituation, Psychophysiologic, Psilocybin","substance_tags":"psilocybin","topic_tags":"Personality Change","study_type":"Other"},{"id":5534,"title":"ChemInform Abstract: CHLORIERTE 2-HYDROXY- UND2-METHOXY-PHENOXYAETHYLAMINE, ANALOGA VON PSILOCYBIN","authors":"Marc Julià, JOEL DE ROSNAY","journal":"Chemischer Informationsdienst Organische Chemie","publication_date":"1971-03-08","doi":"10.1002/chin.197110243","pubmed_id":null,"source_url":"https://doi.org/10.1002/chin.197110243","source_name":"OpenAlex","publication_status":"published","keywords":"Psilocybin, Chemistry, Medicinal chemistry, Hallucinogen, Pharmacology, Medicine, Fluorine in Organic Chemistry, Organic Chemistry Cycloaddition Reactions, Chemical Reactions and Mechanisms","substance_tags":"psilocybin","topic_tags":"Pharmacology,Mechanism of Action","study_type":"Other"},{"id":2874,"title":"Different reaction of focal and diffuse epileptic EEG activity to psilocybin.","authors":"Kolarík J.","journal":null,"publication_date":"1970-12-31","doi":null,"pubmed_id":"5000337","source_url":"https://europepmc.org/article/MED/5000337","source_name":"Europe PMC","publication_status":"published","keywords":"Brain, Thalamus, Cerebral Cortex, Neurons, Humans, Epilepsy, Epilepsies, Partial, Electroencephalography, Psilocybin","substance_tags":"psilocybin","topic_tags":"Brain Imaging","study_type":"Other"},{"id":2873,"title":"EEG changes after psilocybin in organic brain lesions.","authors":"Kolarĩk J.","journal":null,"publication_date":"1970-12-31","doi":null,"pubmed_id":"5122145","source_url":"https://europepmc.org/article/MED/5122145","source_name":"Europe PMC","publication_status":"published","keywords":"Thalamus, Occipital Lobe, Humans, Brain Neoplasms, Brain Diseases, Psychoses, Substance-Induced, Electroencephalography, Psilocybin","substance_tags":"psilocybin","topic_tags":"Brain Imaging","study_type":"Other"},{"id":2123,"title":"ChemInform Abstract: INDOLE 22. MITT. INDOLSYNTH., ANWENDUNG AUF PSILOCIN","authors":"JULIA MARC, PASCAL YVES ROBERT","journal":"Chemischer Informationsdienst. 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PICKER, R. W. RICKARDS","journal":"Chemischer Informationsdienst Organische Chemie","publication_date":"1970-07-20","doi":"10.1002/chin.197029316","pubmed_id":null,"source_url":"https://doi.org/10.1002/chin.197029316","source_name":"OpenAlex","publication_status":"published","keywords":"Psilocybin, Library science, Information retrieval, Advertising, Computer science, Psychology, Business, Psychiatry, Hallucinogen, Chemical synthesis and alkaloids, Molecular spectroscopy and chirality, Asymmetric Synthesis and Catalysis","substance_tags":"psilocybin","topic_tags":"General","study_type":"Other"},{"id":5541,"title":"Psilocybin-Induced Transformations of Visual Space","authors":"Richard Hill, Roland A. 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