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            "title": "Bridging the reporting gap: Application of the ReSPCT guidelines in psilocybin clinical trial protocols",
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            "title": "Psilocybin intoxication did not affect daytime or sleep-related declarative memory consolidation in a small sample exploratory analysis",
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            "title": "P.0593 Lasting effects of a single psilocybin dose on resting-state functional connectivity in healthy individuals",
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            "abstract": "",
            "journal": "European Neuropsychopharmacology",
            "publication_date": "2021-11-30",
            "publication_year": 2021,
            "doi": "10.1016/j.euroneuro.2021.10.687",
            "pubmed_id": null,
            "source_url": "https://doi.org/10.1016/j.euroneuro.2021.10.687",
            "keywords": "Psilocybin, Psychology, Audiology, Cognitive psychology, Medicine, Hallucinogen, Psychiatry, Psychedelics and Drug Studies, Chemical synthesis and alkaloids, Paranormal Experiences and Beliefs",
            "substance_tags": "psilocybin",
            "source_name": "OpenAlex",
            "date_added": "2026-07-04 06:51:58",
            "last_checked": "2026-07-04 07:00:38",
            "raw_json": "{\"openalex_id\":\"https://openalex.org/W4200119156\",\"openalex_url\":\"https://openalex.org/W4200119156\",\"openalex_relevance_score\":6,\"openalex_relevance_reasons\":[\"title:psilocybin\",\"metadata:psilocybin\"],\"openalex_type\":\"article\",\"openalex_work_type\":null,\"cited_by_count\":0,\"referenced_works\":[\"https://openalex.org/W1144621943\",\"https://openalex.org/W2164480306\",\"https://openalex.org/W2784069100\",\"https://openalex.org/W2890356717\",\"https://openalex.org/W2914255920\"],\"authorships\":[{\"id\":\"https://openalex.org/A5004791170\",\"display_name\":\"Dea Siggaard Stenbæk\",\"orcid\":\"https://orcid.org/0000-0002-5439-4637\"},{\"id\":\"https://openalex.org/A5000203733\",\"display_name\":\"M. Madsen\",\"orcid\":\"https://orcid.org/0000-0001-8836-1844\"},{\"id\":\"https://openalex.org/A5086179765\",\"display_name\":\"Sophia Armand\",\"orcid\":\"https://orcid.org/0000-0001-6368-3329\"},{\"id\":\"https://openalex.org/A5013000650\",\"display_name\":\"Catharina Messel\",\"orcid\":null},{\"id\":\"https://openalex.org/A5062586544\",\"display_name\":\"Maria Zofia Grzywacz\",\"orcid\":null},{\"id\":\"https://openalex.org/A5044907549\",\"display_name\":\"David Erritzøe\",\"orcid\":\"https://orcid.org/0000-0002-7022-6211\"},{\"id\":\"https://openalex.org/A5015895924\",\"display_name\":\"Gitte M. Knudsen\",\"orcid\":\"https://orcid.org/0000-0003-1508-6866\"},{\"id\":\"https://openalex.org/A5021085020\",\"display_name\":\"Patrick M. Fisher\",\"orcid\":\"https://orcid.org/0000-0002-8115-0611\"}],\"primary_location\":{\"source_id\":\"https://openalex.org/S168041952\",\"source_display_name\":\"European Neuropsychopharmacology\",\"landing_page_url\":\"https://doi.org/10.1016/j.euroneuro.2021.10.687\",\"is_oa\":false}}",
            "topic_tags": "Emotional Processing",
            "study_type": "Other",
            "hidden": 0,
            "false_positive": 0,
            "curation_notes": null,
            "merged_into_id": null,
            "curation_locked": 0,
            "publication_status": "published",
            "openalex_id": "https://openalex.org/W4200119156"
        },
        {
            "id": 5035,
            "title": "P.0298 Evaluation of the acute mechanism of action of psilocybin in mice",
            "normalized_title": "p 0298 evaluation of the acute mechanism of action of psilocybin in mice",
            "authors": "Ines Erkizia-Santamaría, R. Alles-Pascual, Igor Horrillo, J. Javier Meana, Jorge E. Ortega",
            "abstract": "",
            "journal": "European Neuropsychopharmacology",
            "publication_date": "2021-11-30",
            "publication_year": 2021,
            "doi": "10.1016/j.euroneuro.2021.10.282",
            "pubmed_id": null,
            "source_url": "https://doi.org/10.1016/j.euroneuro.2021.10.282",
            "keywords": "Maillard reaction, Antibacterial activity, Chemistry, Bacillus subtilis, Zinc, Reactive oxygen species, Phenylalanine, Bacteria, Escherichia coli, Combinatorial chemistry, Biochemistry, Stereochemistry, Medicinal chemistry, Nuclear chemistry, Amino acid, Organic chemistry, Biology, Genetics, Gene, Psychedelics and Drug Studies, Phenothiazines and Benzothiazines Synthesis and Activities, Biochemical Analysis and Sensing Techniques",
            "substance_tags": "psilocybin",
            "source_name": "OpenAlex",
            "date_added": "2026-07-04 06:51:58",
            "last_checked": "2026-07-04 07:00:38",
            "raw_json": "{\"openalex_id\":\"https://openalex.org/W4200083165\",\"openalex_url\":\"https://openalex.org/W4200083165\",\"openalex_relevance_score\":4,\"openalex_relevance_reasons\":[\"title:psilocybin\"],\"openalex_type\":\"article\",\"openalex_work_type\":null,\"cited_by_count\":0,\"referenced_works\":[\"https://openalex.org/W2009134620\",\"https://openalex.org/W2107441654\",\"https://openalex.org/W2398898762\"],\"authorships\":[{\"id\":\"https://openalex.org/A5064629089\",\"display_name\":\"Ines Erkizia-Santamaría\",\"orcid\":\"https://orcid.org/0000-0002-6163-4571\"},{\"id\":\"https://openalex.org/A5007763947\",\"display_name\":\"R. Alles-Pascual\",\"orcid\":null},{\"id\":\"https://openalex.org/A5028869928\",\"display_name\":\"Igor Horrillo\",\"orcid\":\"https://orcid.org/0000-0003-0125-5884\"},{\"id\":\"https://openalex.org/A5024198476\",\"display_name\":\"J. Javier Meana\",\"orcid\":\"https://orcid.org/0000-0002-7913-6714\"},{\"id\":\"https://openalex.org/A5033481973\",\"display_name\":\"Jorge E. Ortega\",\"orcid\":\"https://orcid.org/0000-0001-8188-874X\"}],\"primary_location\":{\"source_id\":\"https://openalex.org/S168041952\",\"source_display_name\":\"European Neuropsychopharmacology\",\"landing_page_url\":\"https://doi.org/10.1016/j.euroneuro.2021.10.282\",\"is_oa\":false}}",
            "topic_tags": "Mechanism of Action,Oxidative Stress,Animal Study",
            "study_type": "Animal Study",
            "hidden": 0,
            "false_positive": 0,
            "curation_notes": null,
            "merged_into_id": null,
            "curation_locked": 0,
            "publication_status": "published",
            "openalex_id": "https://openalex.org/W4200083165"
        },
        {
            "id": 5034,
            "title": "P.0623 The clinical relevance of the pharmacokinetics of psilocybin",
            "normalized_title": "p 0623 the clinical relevance of the pharmacokinetics of psilocybin",
            "authors": "A. Andreiev, E. Bucuci, James Chue, Charl Els, Pierre Chue",
            "abstract": "Nicotine dependence is a reversible risk factor of numerous oral cavity diseases. Dentist should be non-smoking and have knowledge on diagnosis and treatment of nicotine addiction.The aim of this survey is the assessment of prevalence of nicotine dependence among Polish dentists, factors associated with this addiction and knowledge on minimal anti-nicotine intervention acquired during pre- and post-graduate training.From October 2013 to March 2014 during 5 dental conferences dental practitioners (881 persons) were given anonymous proprietary questionnaires on nicotine use. 544 questionnaires were qualified for analysis, response rate 61.7%.Group of active nicotine users consisted of 72 persons (13.2% of respondents). The average duration of smoking was 20 years and number of cigarettes smoked daily was 15. Median level of nicotine dependence score 5 and predominance of scores in the range of 4-6 on Fagerström test indicate that most frequent was moderate dependence. As many as 44.4% of dentists in this group had no attempts to quit the addiction. Non-smokers prevailed among women, pedodontists and younger practitioners. Active nicotine users prevailed in dentists above 44 years of age, male, dental surgeons and maxillofacial surgeons. Up to 397 (73%) respondents declared they were never acquainted with the basis for minimal anti-nicotine intervention.The prevalence of nicotine addiction among Polish dentists is lower by 10% compared to the general population, although in relation to current foreign studies its the average level. Main factors associated with active nicotine use in this occupational group include male gender, increasing age and surgical dental specialties. It should be intended to reduce number of nicotine users among Polish dentists by 5%. For this purpose professional anti-nicotine knowledge should be disseminated more.",
            "journal": "European Neuropsychopharmacology",
            "publication_date": "2021-11-30",
            "publication_year": 2021,
            "doi": "10.1016/j.euroneuro.2021.10.588",
            "pubmed_id": null,
            "source_url": "https://doi.org/10.1016/j.euroneuro.2021.10.588",
            "keywords": "Nicotine, Addiction, Medicine, Nicotine dependence, Intervention (counseling), Population, Smoking cessation, Nicotine Addiction, Statistical significance, Dentistry, Psychiatry, Environmental health, Internal medicine, Pathology, Psychedelics and Drug Studies, Nicotinic Acetylcholine Receptors Study, Biochemical Analysis and Sensing Techniques",
            "substance_tags": "psilocybin",
            "source_name": "OpenAlex",
            "date_added": "2026-07-04 06:51:58",
            "last_checked": "2026-07-04 07:00:38",
            "raw_json": "{\"openalex_id\":\"https://openalex.org/W4200545220\",\"openalex_url\":\"https://openalex.org/W4200545220\",\"openalex_relevance_score\":4,\"openalex_relevance_reasons\":[\"title:psilocybin\"],\"openalex_type\":\"article\",\"openalex_work_type\":null,\"cited_by_count\":1,\"referenced_works\":[\"https://openalex.org/W2154105276\",\"https://openalex.org/W2572835720\",\"https://openalex.org/W2622982732\"],\"authorships\":[{\"id\":\"https://openalex.org/A5011301440\",\"display_name\":\"A. Andreiev\",\"orcid\":null},{\"id\":\"https://openalex.org/A5027930147\",\"display_name\":\"E. Bucuci\",\"orcid\":null},{\"id\":\"https://openalex.org/A5033757501\",\"display_name\":\"James Chue\",\"orcid\":null},{\"id\":\"https://openalex.org/A5003495786\",\"display_name\":\"Charl Els\",\"orcid\":\"https://orcid.org/0000-0002-1177-2984\"},{\"id\":\"https://openalex.org/A5061983678\",\"display_name\":\"Pierre Chue\",\"orcid\":\"https://orcid.org/0000-0002-7916-415X\"}],\"primary_location\":{\"source_id\":\"https://openalex.org/S168041952\",\"source_display_name\":\"European Neuropsychopharmacology\",\"landing_page_url\":\"https://doi.org/10.1016/j.euroneuro.2021.10.588\",\"is_oa\":true}}",
            "topic_tags": "Addiction,Pharmacology,Receptor Pharmacology,Observational Study,Safety",
            "study_type": "Observational Study",
            "hidden": 0,
            "false_positive": 0,
            "curation_notes": null,
            "merged_into_id": null,
            "curation_locked": 0,
            "publication_status": "published",
            "openalex_id": "https://openalex.org/W4200545220"
        },
        {
            "id": 5033,
            "title": "P.0885 The effect of psilocybin therapy for depression on low-frequency brain activity in response to music",
            "normalized_title": "p 0885 the effect of psilocybin therapy for depression on low frequency brain activity in response to music",
            "authors": "Matthew B. Wall, Cynthia Lam, Natalie Ertl, Mendel Kaelen, Leor Roseman, David Nutt, Robin Carhart-Harris",
            "abstract": "",
            "journal": "European Neuropsychopharmacology",
            "publication_date": "2021-11-30",
            "publication_year": 2021,
            "doi": "10.1016/j.euroneuro.2021.10.741",
            "pubmed_id": null,
            "source_url": "https://doi.org/10.1016/j.euroneuro.2021.10.741",
            "keywords": "Glucocorticoid receptor, Endocrinology, Glucocorticoid, Internal medicine, Mineralocorticoid receptor, Mineralocorticoid, Receptor, In vivo, Gene expression, Corticosterone, Medicine, Psychology, Chemistry, Biology, Gene, Hormone, Biochemistry, Biotechnology, Psychedelics and Drug Studies, Biochemical Analysis and Sensing Techniques, Olfactory and Sensory Function Studies",
            "substance_tags": "psilocybin",
            "source_name": "OpenAlex",
            "date_added": "2026-07-04 06:51:58",
            "last_checked": "2026-07-04 07:00:38",
            "raw_json": "{\"openalex_id\":\"https://openalex.org/W4200025628\",\"openalex_url\":\"https://openalex.org/W4200025628\",\"openalex_relevance_score\":4,\"openalex_relevance_reasons\":[\"title:psilocybin\"],\"openalex_type\":\"article\",\"openalex_work_type\":null,\"cited_by_count\":1,\"referenced_works\":[\"https://openalex.org/W2762746674\",\"https://openalex.org/W2781340150\",\"https://openalex.org/W2890356717\",\"https://openalex.org/W3156937150\"],\"authorships\":[{\"id\":\"https://openalex.org/A5069665617\",\"display_name\":\"Matthew B. Wall\",\"orcid\":\"https://orcid.org/0000-0002-0493-6274\"},{\"id\":\"https://openalex.org/A5060868416\",\"display_name\":\"Cynthia Lam\",\"orcid\":\"https://orcid.org/0000-0003-1434-7411\"},{\"id\":\"https://openalex.org/A5004040027\",\"display_name\":\"Natalie Ertl\",\"orcid\":\"https://orcid.org/0000-0002-9010-1870\"},{\"id\":\"https://openalex.org/A5019717586\",\"display_name\":\"Mendel Kaelen\",\"orcid\":\"https://orcid.org/0000-0002-6987-9346\"},{\"id\":\"https://openalex.org/A5020826324\",\"display_name\":\"Leor Roseman\",\"orcid\":\"https://orcid.org/0000-0001-9990-6029\"},{\"id\":\"https://openalex.org/A5101507504\",\"display_name\":\"David Nutt\",\"orcid\":\"https://orcid.org/0000-0002-6423-9411\"},{\"id\":\"https://openalex.org/A5038609897\",\"display_name\":\"Robin Carhart-Harris\",\"orcid\":null}],\"primary_location\":{\"source_id\":\"https://openalex.org/S168041952\",\"source_display_name\":\"European Neuropsychopharmacology\",\"landing_page_url\":\"https://doi.org/10.1016/j.euroneuro.2021.10.741\",\"is_oa\":false}}",
            "topic_tags": "Depression,Receptor Pharmacology",
            "study_type": "Other",
            "hidden": 0,
            "false_positive": 0,
            "curation_notes": null,
            "merged_into_id": null,
            "curation_locked": 0,
            "publication_status": "published",
            "openalex_id": "https://openalex.org/W4200025628"
        },
        {
            "id": 5032,
            "title": "P.0729 Highlights of psychedelic history and current research on psilocybin application for treatment of depression - a comprehensive literature review",
            "normalized_title": "p 0729 highlights of psychedelic history and current research on psilocybin application for treatment of depression a comprehensive literature review",
            "authors": "Sara Penedos, Caio Freitas Ramos, María José López Miguel, Márcio José Martins Alves, Luciana Campos Paulino, Adriano Valério S. Azevêdo, M. Magalhães, L. Moreno, N. Ribeiro, Inês Fonseca, Ana Margarida Romão Franco, Luís Madruga, A. Gamito",
            "abstract": "",
            "journal": "European Neuropsychopharmacology",
            "publication_date": "2021-11-30",
            "publication_year": 2021,
            "doi": "10.1016/j.euroneuro.2021.10.797",
            "pubmed_id": null,
            "source_url": "https://doi.org/10.1016/j.euroneuro.2021.10.797",
            "keywords": "Psilocybin, Hallucinogen, Anorexia nervosa, Psychology, Psychiatry, Psychotherapist, Medicine, Eating disorders, Psychedelics and Drug Studies, Chemical synthesis and alkaloids, Complementary and Alternative Medicine Studies",
            "substance_tags": "psilocybin",
            "source_name": "OpenAlex",
            "date_added": "2026-07-04 06:51:58",
            "last_checked": "2026-07-04 07:00:38",
            "raw_json": "{\"openalex_id\":\"https://openalex.org/W4200007802\",\"openalex_url\":\"https://openalex.org/W4200007802\",\"openalex_relevance_score\":6,\"openalex_relevance_reasons\":[\"title:psilocybin\",\"metadata:psilocybin\"],\"openalex_type\":\"article\",\"openalex_work_type\":null,\"cited_by_count\":1,\"referenced_works\":[\"https://openalex.org/W2001101493\",\"https://openalex.org/W2118739111\",\"https://openalex.org/W2558412547\",\"https://openalex.org/W3000549374\",\"https://openalex.org/W3156937150\"],\"authorships\":[{\"id\":\"https://openalex.org/A5083222535\",\"display_name\":\"Sara Penedos\",\"orcid\":null},{\"id\":\"https://openalex.org/A5110579190\",\"display_name\":\"Caio Freitas Ramos\",\"orcid\":null},{\"id\":\"https://openalex.org/A5110827741\",\"display_name\":\"María José López Miguel\",\"orcid\":null},{\"id\":\"https://openalex.org/A5042484784\",\"display_name\":\"Márcio José Martins Alves\",\"orcid\":\"https://orcid.org/0000-0003-0609-4338\"},{\"id\":\"https://openalex.org/A5030060528\",\"display_name\":\"Luciana Campos Paulino\",\"orcid\":\"https://orcid.org/0000-0003-2421-5236\"},{\"id\":\"https://openalex.org/A5112719935\",\"display_name\":\"Adriano Valério S. Azevêdo\",\"orcid\":null},{\"id\":\"https://openalex.org/A5081163504\",\"display_name\":\"M. Magalhães\",\"orcid\":\"https://orcid.org/0009-0008-2218-8493\"},{\"id\":\"https://openalex.org/A5111421995\",\"display_name\":\"L. Moreno\",\"orcid\":null},{\"id\":\"https://openalex.org/A5070677892\",\"display_name\":\"N. Ribeiro\",\"orcid\":\"https://orcid.org/0000-0002-7704-498X\"},{\"id\":\"https://openalex.org/A5040643475\",\"display_name\":\"Inês Fonseca\",\"orcid\":\"https://orcid.org/0000-0001-6777-069X\"},{\"id\":\"https://openalex.org/A5083355508\",\"display_name\":\"Ana Margarida Romão Franco\",\"orcid\":\"https://orcid.org/0000-0002-2035-0599\"},{\"id\":\"https://openalex.org/A5110752961\",\"display_name\":\"Luís Madruga\",\"orcid\":null},{\"id\":\"https://openalex.org/A5107932784\",\"display_name\":\"A. Gamito\",\"orcid\":null}],\"primary_location\":{\"source_id\":\"https://openalex.org/S168041952\",\"source_display_name\":\"European Neuropsychopharmacology\",\"landing_page_url\":\"https://doi.org/10.1016/j.euroneuro.2021.10.797\",\"is_oa\":false}}",
            "topic_tags": "Depression,Eating Disorders,Review Article",
            "study_type": "Review Article",
            "hidden": 0,
            "false_positive": 0,
            "curation_notes": null,
            "merged_into_id": null,
            "curation_locked": 0,
            "publication_status": "published",
            "openalex_id": "https://openalex.org/W4200007802"
        },
        {
            "id": 2022,
            "title": "P.0553 Effect of chronic microdosing of psilocin on cell proliferation and behavior in rats",
            "normalized_title": "p 0553 effect of chronic microdosing of psilocin on cell proliferation and behavior in rats",
            "authors": "Olejníková L., Danda H., Lhotková E., Kútná V., Šíchová K., Syrová K., Mazochová K., Páleníček T.",
            "abstract": "",
            "journal": "European Neuropsychopharmacology",
            "publication_date": "2021-11-30",
            "publication_year": 2021,
            "doi": "10.1016/j.euroneuro.2021.10.523",
            "pubmed_id": null,
            "source_url": "https://doi.org/10.1016/j.euroneuro.2021.10.523",
            "keywords": "",
            "substance_tags": "psilocin",
            "source_name": "Crossref",
            "date_added": "2026-07-01 06:52:05",
            "last_checked": "2026-07-01 11:21:33",
            "raw_json": "{\"doi\":\"10.1016/j.euroneuro.2021.10.523\",\"reference_dois\":[],\"reference_count\":0}",
            "topic_tags": "Microdosing",
            "study_type": "Other",
            "hidden": 0,
            "false_positive": 0,
            "curation_notes": null,
            "merged_into_id": null,
            "curation_locked": 0,
            "publication_status": "published",
            "openalex_id": "https://openalex.org/W4200460234"
        },
        {
            "id": 2021,
            "title": "P.0858 Psilocin induces perceptual alterations in rats: visual discrimination study",
            "normalized_title": "p 0858 psilocin induces perceptual alterations in rats visual discrimination study",
            "authors": "Vejmola Č., Syrová K., Koudelka V., Šíchová K., Tesař M., Dodoková A., Kelemen E., Páleníček T.",
            "abstract": "",
            "journal": "European Neuropsychopharmacology",
            "publication_date": "2021-11-30",
            "publication_year": 2021,
            "doi": "10.1016/j.euroneuro.2021.10.715",
            "pubmed_id": null,
            "source_url": "https://doi.org/10.1016/j.euroneuro.2021.10.715",
            "keywords": "",
            "substance_tags": "psilocin",
            "source_name": "Crossref",
            "date_added": "2026-07-01 06:52:05",
            "last_checked": "2026-07-01 11:21:33",
            "raw_json": "{\"doi\":\"10.1016/j.euroneuro.2021.10.715\",\"reference_dois\":[\"10.1001/archneurol.2010.35\",\"10.1136/bcr-2018-224340\",\"10.1016/j.neuroscience.2014.12.025\",\"10.1016/j.bbr.2017.07.040\"],\"reference_count\":4}",
            "topic_tags": "General",
            "study_type": "Other",
            "hidden": 0,
            "false_positive": 0,
            "curation_notes": null,
            "merged_into_id": null,
            "curation_locked": 0,
            "publication_status": "published",
            "openalex_id": "https://openalex.org/W4200425394"
        },
        {
            "id": 1912,
            "title": "Psilocybin-induced changes in brain network integrity and segregation correlate with plasma psilocin level and psychedelic experience.",
            "normalized_title": "psilocybin induced changes in brain network integrity and segregation correlate with plasma psilocin level and psychedelic experience",
            "authors": "Madsen MK, Stenbæk DS, Arvidsson A, Armand S, Marstrand-Joergensen MR, Johansen SS, Linnet K, Ozenne B, Knudsen GM, Fisher PM.",
            "abstract": "The emerging novel therapeutic psilocybin produces psychedelic effects via engagement of cerebral serotonergic targets by psilocin (active metabolite). The serotonin 2A receptor critically mediates these effects by altering distributed neural processes that manifest as increased entropy, reduced functional connectivity (FC) within discrete brain networks (i.e., reduced integrity) and increased FC between networks (i.e., reduced segregation). Reduced integrity of the default mode network (DMN) is proposed to play a particularly prominent role in psychedelic phenomenology, including perceived ego-dissolution. Here, we investigate the effects of a psychoactive peroral dose of psilocybin (0.2-0.3 mg/kg) on plasma psilocin level (PPL), subjective drug intensity (SDI) and their association in fifteen healthy individuals. We further evaluate associations between these measures and resting-state FC, measured with functional magnetic resonance imaging, acquired over the course of five hours after psilocybin administration. We show that PPL and SDI correlate negatively with measures of network integrity (including DMN) and segregation, both spatially constrained and unconstrained. We also find that the executive control network and dorsal attention network desegregate, increasing connectivity with other networks and throughout the brain as a function of PPL and SDI. These findings provide direct evidence that psilocin critically shapes the time course and magnitude of changes in the cerebral functional architecture and subjective experience following psilocybin administration. Our findings provide novel insight into the neurobiological mechanisms underlying profound perceptual experiences evoked by this emerging transnosological therapeutic and implicate the expression of network integrity and segregation in the psychedelic experience and consciousness.",
            "journal": "European Neuropsychopharmacology",
            "publication_date": "2021-07-07",
            "publication_year": 2021,
            "doi": "10.1016/j.euroneuro.2021.06.001",
            "pubmed_id": "34246868",
            "source_url": "https://doi.org/10.1016/j.euroneuro.2021.06.001",
            "keywords": "Brain, Humans, Hallucinogens, Magnetic Resonance Imaging, Psilocybin",
            "substance_tags": "psilocybin,psilocin",
            "source_name": "Europe PMC",
            "date_added": "2026-07-01 06:48:06",
            "last_checked": "2026-07-04 07:00:38",
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            "authors": "Mie Madsen, P.M. Fisher, D.S. Stenbæk, S. Kristiansen, D. Burmester, S. Lehel, Tomáš Páleníček, Claus Svarer, B. Ozenne, Gitte M. Knudsen",
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            "pubmed_id": null,
            "source_url": "https://doi.org/10.1016/j.euroneuro.2018.11.477",
            "keywords": "Baclofen, Psychology, Reinforcement, Reinforcement learning, Addiction, Neuroscience, Agonist, GABAB receptor, Craving, Medicine, Receptor, Internal medicine, Computer science, Artificial intelligence, Social psychology, Neurotransmitter Receptor Influence on Behavior, Psychedelics and Drug Studies, Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes",
            "substance_tags": "psilocybin",
            "source_name": "OpenAlex",
            "date_added": "2026-07-02 20:42:13",
            "last_checked": "2026-07-04 07:00:39",
            "raw_json": "{\"openalex_id\":\"https://openalex.org/W2912928498\",\"openalex_url\":\"https://openalex.org/W2912928498\",\"openalex_relevance_score\":4,\"openalex_relevance_reasons\":[\"title:psilocybin\"],\"openalex_type\":\"article\",\"openalex_work_type\":null,\"cited_by_count\":0,\"referenced_works\":[\"https://openalex.org/W2180876467\",\"https://openalex.org/W2345771415\"],\"authorships\":[{\"id\":\"https://openalex.org/A5059673219\",\"display_name\":\"P. Dürler\",\"orcid\":null}],\"primary_location\":{\"source_id\":\"https://openalex.org/S168041952\",\"source_display_name\":\"European Neuropsychopharmacology\",\"landing_page_url\":\"https://doi.org/10.1016/j.euroneuro.2018.11.477\",\"is_oa\":false}}",
            "topic_tags": "Depression,Anxiety,Addiction,Receptor Pharmacology",
            "study_type": "Other",
            "hidden": 0,
            "false_positive": 0,
            "curation_notes": null,
            "merged_into_id": null,
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            "publication_status": "published",
            "openalex_id": "https://openalex.org/W2912928498"
        },
        {
            "id": 2043,
            "title": "Psilocybin occupancy of brain serotonin 2A receptors correlates with psilocin levels and subjective experience: a [11C]Cimbi-36 PET study in humans",
            "normalized_title": "psilocybin occupancy of brain serotonin 2a receptors correlates with psilocin levels and subjective experience a 11c cimbi 36 pet study in humans",
            "authors": "M. Madsen, Daniel Burmester, Dea Siggaard Stenbæk, Søren Kristiansen, Agnete Dyssegaard, Szabolcs Lehel, Kristían Línnet, Sys Stybe Johansen, Claus Svarer, Brice Ozenne, David Erritzøe, Patrick M. Fisher, Gitte M. Knudsen",
            "abstract": "",
            "journal": "European Neuropsychopharmacology",
            "publication_date": "2018-12-31",
            "publication_year": 2018,
            "doi": "10.1016/j.euroneuro.2018.11.474",
            "pubmed_id": null,
            "source_url": "https://doi.org/10.1016/j.euroneuro.2018.11.474",
            "keywords": "Visual analogue scale, Medicine, Recall, Analysis of variance, Orthopedic surgery, Anesthesia, Physical therapy, Surgery, Psychology, Internal medicine, Cognitive psychology, Psychedelics and Drug Studies, Neurotransmitter Receptor Influence on Behavior, Chemical synthesis and alkaloids",
            "substance_tags": "psilocybin,psilocin",
            "source_name": "OpenAlex",
            "date_added": "2026-07-01 06:52:05",
            "last_checked": "2026-07-04 07:00:39",
            "raw_json": "{\"openalex_id\":\"https://openalex.org/W2913453568\",\"openalex_url\":\"https://openalex.org/W2913453568\",\"openalex_relevance_score\":8,\"openalex_relevance_reasons\":[\"title:psilocybin\",\"title:psilocin\"],\"openalex_type\":\"article\",\"openalex_work_type\":null,\"cited_by_count\":3,\"referenced_works\":[\"https://openalex.org/W1981968329\",\"https://openalex.org/W2396675581\",\"https://openalex.org/W2558412547\",\"https://openalex.org/W4211211437\",\"https://openalex.org/W6712001975\"],\"authorships\":[{\"id\":\"https://openalex.org/A5000203733\",\"display_name\":\"M. Madsen\",\"orcid\":\"https://orcid.org/0000-0001-8836-1844\"},{\"id\":\"https://openalex.org/A5038013112\",\"display_name\":\"Daniel Burmester\",\"orcid\":\"https://orcid.org/0000-0001-7215-4269\"},{\"id\":\"https://openalex.org/A5004791170\",\"display_name\":\"Dea Siggaard Stenbæk\",\"orcid\":\"https://orcid.org/0000-0002-5439-4637\"},{\"id\":\"https://openalex.org/A5075305785\",\"display_name\":\"Søren Kristiansen\",\"orcid\":\"https://orcid.org/0000-0003-1851-5363\"},{\"id\":\"https://openalex.org/A5057598537\",\"display_name\":\"Agnete Dyssegaard\",\"orcid\":null},{\"id\":\"https://openalex.org/A5086881197\",\"display_name\":\"Szabolcs Lehel\",\"orcid\":\"https://orcid.org/0000-0001-7400-6980\"},{\"id\":\"https://openalex.org/A5078174062\",\"display_name\":\"Kristían Línnet\",\"orcid\":\"https://orcid.org/0000-0001-6974-5535\"},{\"id\":\"https://openalex.org/A5013055423\",\"display_name\":\"Sys Stybe Johansen\",\"orcid\":\"https://orcid.org/0000-0002-9555-5134\"},{\"id\":\"https://openalex.org/A5015994033\",\"display_name\":\"Claus Svarer\",\"orcid\":\"https://orcid.org/0000-0001-7811-1825\"},{\"id\":\"https://openalex.org/A5021739634\",\"display_name\":\"Brice Ozenne\",\"orcid\":\"https://orcid.org/0000-0001-9694-2956\"},{\"id\":\"https://openalex.org/A5044907549\",\"display_name\":\"David Erritzøe\",\"orcid\":\"https://orcid.org/0000-0002-7022-6211\"},{\"id\":\"https://openalex.org/A5021085020\",\"display_name\":\"Patrick M. Fisher\",\"orcid\":\"https://orcid.org/0000-0002-8115-0611\"},{\"id\":\"https://openalex.org/A5015895924\",\"display_name\":\"Gitte M. Knudsen\",\"orcid\":\"https://orcid.org/0000-0003-1508-6866\"}],\"primary_location\":{\"source_id\":\"https://openalex.org/S168041952\",\"source_display_name\":\"European Neuropsychopharmacology\",\"landing_page_url\":\"https://doi.org/10.1016/j.euroneuro.2018.11.474\",\"is_oa\":false}}",
            "topic_tags": "Receptor Pharmacology",
            "study_type": "Other",
            "hidden": 0,
            "false_positive": 0,
            "curation_notes": null,
            "merged_into_id": null,
            "curation_locked": 0,
            "publication_status": "published",
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        },
        {
            "id": 2406,
            "title": "Psilocybin modulates functional connectivity of the amygdala during emotional face discrimination.",
            "normalized_title": "psilocybin modulates functional connectivity of the amygdala during emotional face discrimination",
            "authors": "Grimm O, Kraehenmann R, Preller KH, Seifritz E, Vollenweider FX.",
            "abstract": "Recent studies suggest that the antidepressant effects of the psychedelic 5-HT2A receptor agonist psilocybin are mediated through its modulatory properties on prefrontal and limbic brain regions including the amygdala. To further investigate the effects of psilocybin on emotion processing networks, we studied for the first-time psilocybin's acute effects on amygdala seed-to-voxel connectivity in an event-related face discrimination task in 18 healthy volunteers who received psilocybin and placebo in a double-blind balanced cross-over design. The amygdala has been implicated as a salience detector especially involved in the immediate response to emotional face content. We used beta-series amygdala seed-to-voxel connectivity during an emotional face discrimination task to elucidate the connectivity pattern of the amygdala over the entire brain. When we compared psilocybin to placebo, an increase in reaction time for all three categories of affective stimuli was found. Psilocybin decreased the connectivity between amygdala and the striatum during angry face discrimination. During happy face discrimination, the connectivity between the amygdala and the frontal pole was decreased. No effect was seen during discrimination of fearful faces. Thus, we show psilocybin's effect as a modulator of major connectivity hubs of the amygdala. Psilocybin decreases the connectivity between important nodes linked to emotion processing like the frontal pole or the striatum. Future studies are needed to clarify whether connectivity changes predict therapeutic effects in psychiatric patients.",
            "journal": "European Neuropsychopharmacology",
            "publication_date": "2018-04-24",
            "publication_year": 2018,
            "doi": "10.1016/j.euroneuro.2018.03.016",
            "pubmed_id": "29703645",
            "source_url": "https://doi.org/10.1016/j.euroneuro.2018.03.016",
            "keywords": "Amygdala, Neural Pathways, Humans, Hallucinogens, Double-Blind Method, Emotions, Reaction Time, Adult, Female, Male, Young Adult, Facial Recognition, Psilocybin, Discrimination, Psychological",
            "substance_tags": "psilocybin",
            "source_name": "Europe PMC",
            "date_added": "2026-07-01 06:54:14",
            "last_checked": "2026-07-04 07:00:40",
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            "topic_tags": "Mechanism of Action,Receptor Pharmacology,Emotional Processing,Healthy Volunteers",
            "study_type": "Other",
            "hidden": 0,
            "false_positive": 0,
            "curation_notes": null,
            "merged_into_id": null,
            "curation_locked": 0,
            "publication_status": "published",
            "openalex_id": "https://openalex.org/W2801092899"
        },
        {
            "id": 5229,
            "title": "Psilocybin-induced psychosis in humans and in rats − translational quantitative EEG study",
            "normalized_title": "psilocybin induced psychosis in humans and in rats translational quantitative eeg study",
            "authors": "Filip Tylš, Čestmír Vejmola, Michaela Viktorinová, L. Kadeřábek, Tomáš Páleníček",
            "abstract": "",
            "journal": "European Neuropsychopharmacology",
            "publication_date": "2016-09-30",
            "publication_year": 2016,
            "doi": "10.1016/s0924-977x(16)31133-6",
            "pubmed_id": null,
            "source_url": "https://doi.org/10.1016/s0924-977x(16)31133-6",
            "keywords": "Dopaminergic, Taste, Taste aversion, Prefrontal cortex, Neuroscience, Anhedonia, Extinction (optical mineralogy), Dopamine, Psychology, Latent inhibition, Dopamine receptor, Associative learning, Chemistry, Conditioning, Classical conditioning, Cognition, Mathematics, Mineralogy, Statistics, Neurotransmitter Receptor Influence on Behavior, Psychedelics and Drug Studies, Nicotinic Acetylcholine Receptors Study",
            "substance_tags": "psilocybin",
            "source_name": "OpenAlex",
            "date_added": "2026-07-04 06:52:03",
            "last_checked": "2026-07-04 07:00:40",
            "raw_json": "{\"openalex_id\":\"https://openalex.org/W2541838945\",\"openalex_url\":\"https://openalex.org/W2541838945\",\"openalex_relevance_score\":4,\"openalex_relevance_reasons\":[\"title:psilocybin\"],\"openalex_type\":\"article\",\"openalex_work_type\":null,\"cited_by_count\":0,\"referenced_works\":[],\"authorships\":[{\"id\":\"https://openalex.org/A5012044574\",\"display_name\":\"Filip Tylš\",\"orcid\":\"https://orcid.org/0000-0002-8337-6999\"},{\"id\":\"https://openalex.org/A5009033234\",\"display_name\":\"Čestmír Vejmola\",\"orcid\":\"https://orcid.org/0000-0002-6434-5978\"},{\"id\":\"https://openalex.org/A5018960269\",\"display_name\":\"Michaela Viktorinová\",\"orcid\":\"https://orcid.org/0000-0002-6462-5793\"},{\"id\":\"https://openalex.org/A5074167242\",\"display_name\":\"L. Kadeřábek\",\"orcid\":null},{\"id\":\"https://openalex.org/A5056888000\",\"display_name\":\"Tomáš Páleníček\",\"orcid\":\"https://orcid.org/0000-0002-3109-9539\"}],\"primary_location\":{\"source_id\":\"https://openalex.org/S168041952\",\"source_display_name\":\"European Neuropsychopharmacology\",\"landing_page_url\":\"https://doi.org/10.1016/s0924-977x(16)31133-6\",\"is_oa\":false}}",
            "topic_tags": "Brain Imaging,Receptor Pharmacology",
            "study_type": "Other",
            "hidden": 0,
            "false_positive": 0,
            "curation_notes": null,
            "merged_into_id": null,
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            "publication_status": "published",
            "openalex_id": "https://openalex.org/W2541838945"
        },
        {
            "id": 5228,
            "title": "Psilocybin-induced decrease in amygdala-putamen coupling during an event-related face discrimination task",
            "normalized_title": "psilocybin induced decrease in amygdala putamen coupling during an event related face discrimination task",
            "authors": "O. Grimm, Rainer Krähenmann, Katrin H. Preller, Erich Seifritz, F.X. Vollenweider",
            "abstract": "",
            "journal": "European Neuropsychopharmacology",
            "publication_date": "2016-09-30",
            "publication_year": 2016,
            "doi": "10.1016/s0924-977x(16)31070-7",
            "pubmed_id": null,
            "source_url": "https://doi.org/10.1016/s0924-977x(16)31070-7",
            "keywords": "Psilocybin, Hallucinogen, Psychotomimetic, Serotonergic, Neuroscience, Amygdala, Psychology, Medicine, Cognitive psychology, Psychiatry, Serotonin, NMDA receptor, Internal medicine, Receptor, Psychedelics and Drug Studies, Mental Health and Psychiatry, Neurotransmitter Receptor Influence on Behavior",
            "substance_tags": "psilocybin",
            "source_name": "OpenAlex",
            "date_added": "2026-07-04 06:52:03",
            "last_checked": "2026-07-04 07:00:40",
            "raw_json": "{\"openalex_id\":\"https://openalex.org/W2545855757\",\"openalex_url\":\"https://openalex.org/W2545855757\",\"openalex_relevance_score\":6,\"openalex_relevance_reasons\":[\"title:psilocybin\",\"metadata:psilocybin\"],\"openalex_type\":\"article\",\"openalex_work_type\":null,\"cited_by_count\":1,\"referenced_works\":[],\"authorships\":[{\"id\":\"https://openalex.org/A5037306868\",\"display_name\":\"O. Grimm\",\"orcid\":\"https://orcid.org/0000-0002-0767-0301\"},{\"id\":\"https://openalex.org/A5113153562\",\"display_name\":\"Rainer Krähenmann\",\"orcid\":null},{\"id\":\"https://openalex.org/A5040977207\",\"display_name\":\"Katrin H. Preller\",\"orcid\":\"https://orcid.org/0000-0003-0413-7672\"},{\"id\":\"https://openalex.org/A5045362944\",\"display_name\":\"Erich Seifritz\",\"orcid\":\"https://orcid.org/0000-0002-7311-4426\"},{\"id\":\"https://openalex.org/A5063133386\",\"display_name\":\"F.X. Vollenweider\",\"orcid\":null}],\"primary_location\":{\"source_id\":\"https://openalex.org/S168041952\",\"source_display_name\":\"European Neuropsychopharmacology\",\"landing_page_url\":\"https://doi.org/10.1016/s0924-977x(16)31070-7\",\"is_oa\":false}}",
            "topic_tags": "Receptor Pharmacology",
            "study_type": "Other",
            "hidden": 0,
            "false_positive": 0,
            "curation_notes": null,
            "merged_into_id": null,
            "curation_locked": 0,
            "publication_status": "published",
            "openalex_id": "https://openalex.org/W2545855757"
        },
        {
            "id": 2518,
            "title": "Modulatory effect of the 5-HT1A agonist buspirone and the mixed non-hallucinogenic 5-HT1A/2A agonist ergotamine on psilocybin-induced psychedelic experience.",
            "normalized_title": "modulatory effect of the 5 ht1a agonist buspirone and the mixed non hallucinogenic 5 ht1a 2a agonist ergotamine on psilocybin induced psychedelic experience",
            "authors": "Pokorny T, Preller KH, Kraehenmann R, Vollenweider FX.",
            "abstract": "The mixed serotonin (5-HT) 1A/2A/2B/2C/6/7 receptor agonist psilocybin dose-dependently induces an altered state of consciousness (ASC) that is characterized by changes in sensory perception, mood, thought, and the sense of self. The psychological effects of psilocybin are primarily mediated by 5-HT2A receptor activation. However, accumulating evidence suggests that 5-HT1A or an interaction between 5-HT1A and 5-HT2A receptors may contribute to the overall effects of psilocybin. Therefore, we used a double-blind, counterbalanced, within-subject design to investigate the modulatory effects of the partial 5-HT1A agonist buspirone (20mg p.o.) and the non-hallucinogenic 5-HT2A/1A agonist ergotamine (3mg p.o.) on psilocybin-induced (170 µg/kg p.o.) psychological effects in two groups (n=19, n=17) of healthy human subjects. Psychological effects were assessed using the Altered State of Consciousness (5D-ASC) rating scale. Buspirone significantly reduced the 5D-ASC main scale score for Visionary Restructuralization (VR) (p",
            "journal": "European Neuropsychopharmacology",
            "publication_date": "2016-01-21",
            "publication_year": 2016,
            "doi": "10.1016/j.euroneuro.2016.01.005",
            "pubmed_id": "26875114",
            "source_url": "https://doi.org/10.1016/j.euroneuro.2016.01.005",
            "keywords": "Humans, Consciousness Disorders, Ergotamine, Buspirone, Hallucinogens, Double-Blind Method, Female, Male, Young Adult, Serotonin Receptor Agonists, Healthy Volunteers, Behavior Rating Scale, Psilocybin",
            "substance_tags": "psilocybin",
            "source_name": "Europe PMC",
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