Recruitment status
- Completed16
- Recruiting3
- Active, not recruiting1
- Enrolling by invitation1
Psilocybin-Research.comSearchable psilocybin and psilocin bibliometric database.
Switzerland trial landscape
Psilocybin Clinical Trials in Switzerland
Review psilocybin studies with at least one registry-listed site in Switzerland, including recruitment status, phases, indications, sponsors, and locations.
Registry status is not a guarantee of local availability, eligibility, safety, or efficacy. Confirm every participation decision in the authoritative ClinicalTrials.gov record.
21matching trials
3currently recruiting
15registry-listed sites
Registry facts checkedAug 10, 2026 01:26 UTC
Live registry synthesis
Status, geography, and study phase
Country inclusion is based on structured study-site data rather than sponsor location. Registry status does not guarantee that an individual Swiss site is enrolling.
Leading countries
- Switzerland21
Trial phases
- Phase 112
- Phase 24
- Not applicable2
- Early Phase 12
Server-rendered source index
21 matching registry records
Every factual summary is crawlable without JavaScript. Use the direct registry link for current eligibility, contacts, and site availability.
CompletedNCT06884514
Acute Effects of MDMA Co-administration on the Response to Psilocybin in Healthy Subjects
University Hospital, Basel, Switzerland
- Conditions
- Healthy
- Phase
- Phase 1
- Enrollment
- 24 actual
- Locations
- University Hospital Basel, Basel, Switzerland
- Registry updated
- 2026-06-25
RecruitingNCT05883540
Lysergic Acid Diethylamide (LSD) in Palliative Care: a Randomised, Double-blind, Active-placebo Controlled Phase II Study (LPC-Study)
University Hospital, Basel, Switzerland
- Conditions
- Palliative Care · Pain · Anxiety · Depression
- Phase
- Phase 2
- Enrollment
- 60 estimated
- Locations
- University Hospital Basel, Division of Clinical Pharmacology and Toxicology, Basel, Switzerland · University Hospital Geneva, Palliative medicine department, Collonge-Bellerive, Switzerland · Spital Uster AG, Division of Internal Medicine, Uster, Switzerland · +1 more
- Registry updated
- 2026-04-29
CompletedNCT06180759
Acute Analgesic Effects of DMT on Experimentally Induced Acute Nociceptive Pain, Hyperalgesia and Allodynia in Healthy Participants
University Hospital, Basel, Switzerland
- Conditions
- Healthy
- Phase
- Phase 1
- Enrollment
- 17 actual
- Locations
- Clinical Pharmacology & Toxicology, University Hospital Basel, Basel, Basel, Switzerland
- Registry updated
- 2026-04-02
CompletedNCT06081179
Does Serotonin System Stimulation Increase Pro-social Behavior? - A Comparative Pharmacological Neuroscientific Study in Healthy Humans
University of Zurich
- Conditions
- Healthy
- Phase
- Phase 1
- Enrollment
- 122 actual
- Locations
- Psychiatrische Universitätsklinik Zürich, Zurich, Canton of Zurich, Switzerland
- Registry updated
- 2025-11-19
Active, not recruitingNCT07164287
Retrospective Observational Study of Intensity Effects in Psychedelic-assisted Treatment
University Hospital, Geneva
- Conditions
- Major Depressive Disorder (MDD) · Anxiety Disorders · Substance Use Disorder (SUD) · PTSD - Post Traumatic Stress Disorder
- Phase
- Phase not reported
- Enrollment
- 376 estimated
- Locations
- Geneva University Hospital, Geneva, Switzerland
- Registry updated
- 2025-10-02
RecruitingNCT06796361
Role of the Serotonin 2A Receptor in Psilocybin-induced Altered States of Consciousness (PDR-Study)
University Hospital, Basel, Switzerland
- Conditions
- Healthy
- Phase
- Phase 1
- Enrollment
- 16 estimated
- Locations
- Clinical Trial Unit, Basel, Canton of Basel-City, Switzerland
- Registry updated
- 2025-05-28
Enrolling by invitationNCT05570708
The Role of Personal Experience for the Therapeutic Attitude in the Context of Substance-assisted Therapy Training
Felix Mueller
- Conditions
- Personal Experience of Substance-assisted Therapy Using Psilocybin, MDMA, and LSD
- Phase
- Not applicable
- Enrollment
- 48 estimated
- Locations
- University Hospital Basel, Basel, Switzerland
- Registry updated
- 2025-04-14
CompletedNCT05695495
Acute Dose-dependent Effects of DMT-bolus Applications in Healthy Subjects: A Placebo-controlled Cross-over Study (DMT BDR-Study).
University Hospital, Basel, Switzerland
- Conditions
- Healthy
- Phase
- Phase 1
- Enrollment
- 36 actual
- Locations
- Clinical Pharmacology & Toxicology, University Hospital Basel, Basel, Switzerland
- Registry updated
- 2025-04-11
RecruitingNCT06899334
Direct Comparison of Altered States of Consciousness Induced by LSD, Psilocybin, and DMT in a Randomized, Placebo-controlled, Cross-over Trial in Healthy Participants (LPD-Study)
University Hospital, Basel, Switzerland
- Conditions
- Healthy
- Phase
- Phase 1
- Enrollment
- 24 estimated
- Locations
- University Hospital, Basel, Switzerland
- Registry updated
- 2025-03-27
CompletedNCT06252506
Molecular Imaging Study of Harmine/DMT: a Basic Research Approach
Insel Gruppe AG, University Hospital Bern
- Conditions
- Neuropharmacological Investigation of Ayahuasca Constituents DMT and Harmine
- Phase
- Phase 1
- Enrollment
- 17 actual
- Locations
- Department of Nuclear Medicine, Bern University Hospital, Bern, Switzerland · Psychiatric University Hospital Zurich, Zurich, Switzerland
- Registry updated
- 2025-03-19
CompletedNCT05523401
Acute Effects of 2C-B Compared With MDMA and Psilocybin in Healthy Subjects
University Hospital, Basel, Switzerland
- Conditions
- Healthy
- Phase
- Phase 1
- Enrollment
- 24 actual
- Locations
- University Hospital Basel, Basel, Switzerland
- Registry updated
- 2025-03-05
CompletedNCT05384678
Acute Dose-dependent Effects of DMT in Healthy Subjects: A Placebo-controlled Cross-over Study
University Hospital, Basel, Switzerland
- Conditions
- Healthy
- Phase
- Phase 1
- Enrollment
- 24 actual
- Locations
- Universtity Hospital Basel, Basel, Switzerland
- Registry updated
- 2024-04-25
CompletedNCT04227756
Comparative Acute Effects of LSD, Psilocybin and Mescaline in a Random-Order Placebo-Controlled Cross-Over Study in Healthy Subjects
University Hospital, Basel, Switzerland
- Conditions
- Healthy
- Phase
- Phase 1
- Enrollment
- 32 actual
- Locations
- University Hospital Basel, Clinical Trial Unit, Basel, Canton of Basel-City, Switzerland
- Registry updated
- 2024-01-24
CompletedNCT05780216
Mindfulness and Psychedelics: A Combined Neurophenomenological and Pharmacological Approach to the Characterization of Mindfulness States in Experienced Meditators
Milan Scheidegger
- Conditions
- Healthy Participants
- Phase
- Early Phase 1
- Enrollment
- 40 actual
- Locations
- Psychiatric University Hospital Zurich, Zurich, Switzerland
- Registry updated
- 2023-09-21
CompletedNCT04141501
Phase II, Randomized, Double Blind, Placebo Controlled, Parallel Group, Single Center Study of Psilocybin Efficacy and Mechanism in Alcohol Use Disorder
University of Zurich
- Conditions
- Alcohol Use Disorder
- Phase
- Phase 2
- Enrollment
- 37 actual
- Locations
- Psychiatrische Universitätsklinik Zürich, Zurich, Switzerland
- Registry updated
- 2023-09-21
CompletedNCT04849013
Role of the Serotonin 5-HT2A Receptor in Mescaline-induced Altered States of Consciousness
University Hospital, Basel, Switzerland
- Conditions
- Healthy
- Phase
- Phase 1
- Enrollment
- 16 actual
- Locations
- University Hospital Basel, Clinical Trial Unit, Basel, Canton of Basel-City, Switzerland
- Registry updated
- 2023-03-29
CompletedNCT03715127
Phase II, Randomized, Double Blind, Placebo Controlled, Parallel Group, Single Center Study of Psilocybin Efficacy in Major Depression
University of Zurich
- Conditions
- Depressive Disorder, Major
- Phase
- Phase 2
- Enrollment
- 55 actual
- Locations
- Psychiatrische Universitätsklinik Zürich, Zurich, Switzerland
- Registry updated
- 2022-04-29
CompletedNCT03153579
LSD Treatment in Persons Suffering From Anxiety Symptoms in Severe Somatic Diseases or in Psychiatric Anxiety Disorders: a Randomized, Double-blind, Placebo-controlled Phase II Study
University Hospital, Basel, Switzerland
- Conditions
- Patients · Anxiety Disorders
- Phase
- Phase 2
- Enrollment
- 46 actual
- Locations
- University Hospital Basel, Basel, Canton of Basel-City, Switzerland · Private Practice P.Gasser, Solothurn, Canton of Solothurn, Switzerland
- Registry updated
- 2021-12-22
CompletedNCT03853577
Characterization of Altered Waking States of Consciousness in Healthy Humans
University of Zurich
- Conditions
- Altered Waking States of Consciousness in Healthy Humans
- Phase
- Not applicable
- Enrollment
- 25 actual
- Locations
- Psychiatrische Universitätsklinik Zürich, Zurich, Switzerland
- Registry updated
- 2021-04-29
CompletedNCT03604744
Direct Comparison of Altered States of Consciousness Induced by LSD and Psilocybin in a Random-order Placebo-controlled Cross-over Study in Healthy Subjects
University Hospital, Basel, Switzerland
- Conditions
- Healthy
- Phase
- Early Phase 1
- Enrollment
- 28 actual
- Locations
- Clinical Pharmacology & Toxicology, University Hospital Basel, Basel, Switzerland
- Registry updated
- 2021-04-27
CompletedNCT03912974
Effects of Serotonin Transporter Inhibition on the Subjective Response to Psilocybin in Healthy Subjects
University Hospital, Basel, Switzerland
- Conditions
- Healthy
- Phase
- Phase 1
- Enrollment
- 27 actual
- Locations
- University Hospital Basel, Clinical Trial Unit, Basel, Canton of Basel-City, Switzerland
- Registry updated
- 2020-12-01
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