PENGARUH PEMBERIAN EKSTRAK JAMUR PSILOCYBE CUBENSIS DOSIS BERTINGKAT TERHADAP RASA INGIN TAHU MENCIT SWISS WEBSTER YANG DIUKUR DENGAN MANUAL HOLE BOARD

Background: Psilocybin mushrooms are one of the hallucinatory effect that Psilocybe cubensis. Compounds contained in it may provide psychological effects, effects on the nervous edge mapun behavior. Psychological and behavioral effects can be seen from the level of curiosity. Curiosity is an emotion related to the curious behavior such as exploration, investigation, and learning.Objectives: To determine and analyze the effect of Psilocybe cubensis mushroom extract at a dose rate of curiosity on the rise in male miceMethod: experimental study, simple random sampling methodInterventions: The samples used were male Swiss Webster mice amounted to 20 fish with specific inclusion criteria were divided into 4, the control group (P0), the low-dose group (P1) is given Psilocybe cubensis extract at a dose of 0.75 g / kg, medium-dose group (P2) at a dose of 1.5 g / kg, and high-dose groups (P3) at a dose of 3 g / kg. Each extract in mice dropped as much as 1 times before the study began. After that, test Manual Hole Board for 5 minutes to determine the level of curiosity. Differences in the level of curiosity in the treatment group compared with the control group were analyzed by t test indepent.Results: The average score Manual Hole Board in the control group is equal to 29.80; later in the low-dose group decreased an average score being 24.60; moderate dose group experienced a decline in score of 18.20, while in the high-dose group also score decreased to 7.20. The higher the dose given to the mice will lower the score Manual Hole Board significantly (P