Psilocybin and psilocin research index

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Quantifying psilocybin exposure in a natural product-based retreat setting: An observational field method for dose measurement

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Details DOI 10.1016/j.psyche.2026.100029 Copy citation Copy BibTeX

Psychedelics 2026-12-01 Pérez Rosal Sergio R., Faber Sonya C.

Crossref Published psilocybin Observational Study Observational Study More

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Mindfulness-Based Psilocybin-Assisted Therapy (MB-PAT) for cancer-related demoralization in Canada: The case for a hybrid group-based delivery model

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Details DOI 10.1016/j.psyche.2026.100032 Copy citation Copy BibTeX

Psychedelics 2026-12-01 Albertyn Christopher P., Richard Jérémie, Shore Ron, Carlson Linda E.

Crossref Published psilocybin Cancer Patients Other More

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Pupil-DLC: An open-source deep learning pipeline for scalable, marker-less tracking of pupil dynamics across conscious and unconscious states.

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Details DOI 10.1016/j.jneumeth.2026.110848 PubMed 42401399 Copy citation Copy BibTeX

Journal of neuroscience methods 2026-11-01 Seyfourian P, Marks LC, Claar LD, Nahas Y, Keating M, Koch C

PubMed Published psilocybin Brain ImagingConsciousnessBiomarkers Animal Study More

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Changes in anxiety, quality of life, and functioning following psilocybin-assisted therapy in veterans with treatment-resistant depression

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Details DOI 10.1016/j.jad.2026.122063 PubMed 42248535 Copy citation Copy BibTeX

Journal of Affective Disorders 2026-11-01 Kelly Carlton M., Fradet Mathieu, Bostian Catherine M., Donnelly Anna, Ellis Sara, Ostacher Michael

Crossref Published psilocybin DepressionAnxietyTreatment-Resistant Depression Other More

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Chronic psilocin microdosing produces limited behavioral effects and does not enhance neurogenesis in rats

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Details DOI 10.1016/j.pbb.2026.174231 PubMed 42379524 Copy citation Copy BibTeX

Pharmacology Biochemistry and Behavior 2026-10-01 Ladislavová Lucie, Kútná Viera, Mazochová Kristýna, Šíchová Klára, Danda Hynek, Lhotková Eva

Crossref Published psilocin NeurogenesisMicrodosing Other More

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Prevalence and Reasons for Microdosing Cannabis, Psilocybin, LSD, and MDMA Among U.S. Adults

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Details DOI 10.1016/j.amepre.2026.108381 PubMed 42092643 Copy citation Copy BibTeX

American Journal of Preventive Medicine 2026-10-01 Yang Kevin H., Satybaldiyeva Nora, Kepner Wayne, Friedman Joseph, Ping Siyuan, Leas Eric C.

Crossref Published psilocybin Microdosing Other More

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Single-crystal structure determination of psilocybin after dehydration

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Details DOI 10.1107/s2053229626007692 PubMed 42566287 Copy citation Copy BibTeX

Acta Crystallographica Section C Structural Chemistry 2026-09-01 Emmett Sonya K., Cameron Lee, Hestermann Mark, Holland Darren, Kessler Simon, McFarlane Luke

Crossref Published psilocybin General Clinical Trial More

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Assessing The Readiness of Psychiatrists in Louisiana to Incorporate Psilocybin into Clinical Practice-Lessons Learned from a State Underrepresented in Clinical Psychedelic Research.

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Details DOI 10.1177/28314425251381806 PubMed 42539773 Copy citation Copy BibTeX

Psychedelic medicine (New Rochelle, N.Y.) 2026-09-01 Husein A, Traylor M, Vest MF, Wood BJ, Brogan M, Thomas A

PubMed Published psilocybin AddictionObservational StudySafety Observational Study More

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A Nature-Themed Video Intervention Increases Nature Relatedness in Psilocybin-Assisted Psychotherapy for Alcohol Use Disorder.

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Details DOI 10.1177/28314425251387655 PubMed 42539824 Copy citation Copy BibTeX

Psychedelic medicine (New Rochelle, N.Y.) 2026-09-01 Rich R, Laird K, Siddarth P, Youssef B, Schwartz GM, Ramos A

PubMed Published psilocybin AddictionMechanism of ActionWellbeing Clinical Trial More

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Group Retreat Psilocybin Therapy for People with Metastatic Cancer with Anxiety and Depression: A Rite of Passage Facilitation Model for a Phase 1/2 Study.

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Details DOI 10.1177/28314425251404460 PubMed 42539893 Copy citation Copy BibTeX

Psychedelic medicine (New Rochelle, N.Y.) 2026-09-01 Back AL, McGregor BA, Billingsley L, Blom D, Callan G, Myers S

PubMed Published psilocybin DepressionAnxietyEmotional Processing Clinical Trial More

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Contribution of the Serotonin 5-HT2A Receptor to the Therapeutic Effect of Psilocin on Social Behavior Deficits in Mice Repeatedly Exposed to Social Defeat Stress

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Details DOI 10.1002/npr2.70152 PubMed 42379141 Copy citation Copy BibTeX

Neuropsychopharmacology Reports 2026-09-01 Ibi Daisuke, Takaba Rika, Yoshida Keisuke, Kawase Ririna, Kitagawa Hiroko, Matsushita Momoko

Crossref Published psilocybinpsilocin DepressionAnxietyReceptor Pharmacology Animal Study More

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Balancing safety and access in Oregon’s psilocybin services

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Details DOI 10.1016/j.drugpo.2026.105384 PubMed 42288041 Copy citation Copy BibTeX

International Journal of Drug Policy 2026-09-01 Cheung Katherine, Propes Caleigh, Yaden David B.

Crossref Published psilocybin Safety Other More

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Genome-based optimization of psilocybin and N,N-dimethyltryptamine biosynthetic pathways in E. coli using CRISPR-associated transposases

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Details DOI 10.1016/j.ymben.2026.102490 PubMed 42288133 Copy citation Copy BibTeX

Metabolic Engineering 2026-09-01 Abrahms Zachary N., Majdi Mohammad, Madsen Siena M., Morton Chloe J., Sen Abhishek K., Fried Niya B.

Crossref Published psilocybin Mechanism of ActionGenomics Other More

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Music Playlist Use in Clinical Trials of Psychedelic Assisted Psychotherapy: A Systematic Review.

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Details DOI 10.1002/jclp.70167 PubMed 42296474 Copy citation Copy BibTeX

Journal of clinical psychology 2026-09-01 Cruz L, Beserra FR, Freind JMK, Rodrigues SE, Mograbi DC

PubMed Published psilocybin DepressionPTSDClinical Trial Systematic Review More

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Circulating MicroRNAs and Their Associations with Neurotrophic, Inflammatory and Glutamate Markers in Healthy Volunteers

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Details DOI 10.64898/2026.08.04.742737 Copy citation Copy BibTeX

bioRxiv 2026-08-10 O'Shea, A.; Mason, N. L.; Briede, J.; Schreiber, R.; Verheijen, M.; Krauskopf

New this week bioRxiv PREPRINT (not peer reviewed) psilocybinpsilocin NeuroplasticityPharmacologyBiomarkers Clinical Trial More

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Temporal effects of a single oral dose of psilocybin on plasma circulating miRNAs in healthy young adults.

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Details DOI 10.64898/2026.08.04.742716 Copy citation Copy BibTeX

bioRxiv 2026-08-10 O'Shea, A.; Mason, N. L.; Schreiber, R.; Verheijen, M.; Ramaekers, J.; Briede

New this week bioRxiv PREPRINT (not peer reviewed) psilocybin NeuroplasticityBrain ImagingMechanism of Action Other More

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Psilocybin acutely dissociates cognitive and affective empathy, with empathic concern predicting persisting positive psychological effects

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Details DOI 10.64898/2026.08.04.742704 Copy citation Copy BibTeX

bioRxiv 2026-08-10 Mason, N. L.; Mallaroni, P.; Kuypers, K. P. C.; De La Torre Fornell, R.; Reckweg, J. T.; Preller

New this week bioRxiv PREPRINT (not peer reviewed) psilocybin Brain ImagingEmotional ProcessingHealthy Volunteers Clinical Trial More

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An Open-Label Trial Protocol to Test Menstrual Cycle Effects and Tolerance to Low-Dose Psilocybin in Healthy Menstruating Persons.

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Details DOI 10.1159/pha/aejag002 PubMed 42574302 Copy citation Copy BibTeX

Pharmacology 2026-08-10 Kothiwala FM, Murphy RJ, Alshakhouri M, Douglass HM, Evans WJ, Paterson T

New this week PubMed Published psilocybin Brain ImagingPharmacologyReceptor Pharmacology Other More

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An Investigation of Strategies to Understand and Optimize the Antidepressant Effects of Psilocybin (The OPTIMIZE Study)

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ClinicalTrials.gov 2026-08-10 Charles Raison

New this week ClinicalTrials.gov CLINICAL TRIAL psilocybin DepressionAnxietyAging Clinical Trial More

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A Phase III, Multicentre, Randomised, Double-blind, Controlled Study to Investigate the Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in Participants With Treatment-resistant Depression

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ClinicalTrials.gov 2026-08-10 COMPASS Pathways

New this week ClinicalTrials.gov CLINICAL TRIAL psilocybin DepressionClinical TrialTreatment-Resistant Depression Clinical Trial More