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Psychedelic-Induced Constraint Destabilization and Reconstruction as a Mechanism for Cognitive Reset

Psychedelic experiences are frequently described as producing a “psychological reset,”characterized by reduced rigidity of thought and disruption of maladaptive cognitive pat-terns. Existing models such as REBUS and the entropic brain hypothesis explain acutedestabilization but do not fully account for post-experience reconstruction. This paper pro-poses a two-stage mechanism: (1) constraint destabilization, and (2) partial reconstructioninto a modified configuration. The resulting reset reflects a reconfiguration event ratherthan a return to baseline. The model yields testable predictions grounded in neuroimagingand behavioral measures. keywords: psychedelics, cognitive reset, REBUS, predictive processing, constraint destabilization, neuroplasticity, default mode network, integration, psilocybin

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Journal
Zenodo (CERN European Organization for Nuclear Research)
Date
2026-03-24
Source
OpenAlex
DOI
10.5281/zenodo.19221582
PubMed
Unavailable

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