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Psilocybin and psilocin research index

Find psilocybin and psilocin papers, preprints, trials, and citations with clear source context.

Searches titles, authors, journals, identifiers, indexed metadata, and derived research topics. Use Filters to narrow by source, status, substance, study type, or date.

Database 4,959 indexed records Auto-updated on Aug 17, 2026 01:21 UTC

Executed search Sources: ClinicalTrials.gov 300 matching records are displayed.

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Database

4,740 Psilocybin Records 673 Psilocin Records 1,461 Journals 66 Research Topics

Published 4,221 Peer-reviewed / formal records Preprints 435 Marked as not peer reviewed Clinical trials 300 ClinicalTrials.gov records R toolkit visNetwork Bibliometrics, live SQLite analysis, HTML graph, and PDF export

Top journals 1,461 indexed journals

Journal	Records
Journal of psychopharmacology (Oxford, England)	147
Journal of psychoactive drugs	97
Frontiers in psychiatry	90
Psychopharmacology	85
Neuroscience Applied	57
Journal of Psychedelic Studies	48
Psychedelic medicine (New Rochelle, N.Y.)	39
Scientific reports	37
bioRxiv : the preprint server for biology	33
Biological Psychiatry	32

Research topics 66 topic filters

Depression 1,736 Receptor Pharmacology 1,282 Safety 1,201 Mechanism of Action 1,070 Review Article 1,070 Clinical Trial 975 Anxiety 882 Addiction 823 Pharmacology 753 General 537 Aging 524 Animal Study 524 Observational Study 515 Brain Imaging 481 Treatment-Resistant Depression 417 Emotional Processing 409 PTSD 400 Neuroplasticity 399

Source coverage 8 active sources

Source	Count	Share	Status
PubMed	2,567	51.8%	Active
OpenAlex	1,154	23.3%	Active
Crossref	404	8.1%	Active
ClinicalTrials.gov	300	6%	Active
Europe PMC	187	3.8%	Active
PsyArXiv	187	3.8%	Active
bioRxiv	122	2.5%	Active

Publication timeline 3,856 dated records

3,856 records since 2020

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Substances Psilocybin 4740 Psilocin 673

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Executed search Sources: ClinicalTrials.gov 300 matching records are displayed.

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300 matching records for Sources: ClinicalTrials.gov.

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Effect of Psilocybin Only and Psilocybin Assisted Cognitive Behavioral Therapy in the Management of Major Depressive Disorder and Associated Metabolic, Immune, Inflammatory, Neuroplasticity and Electrical Activity Markers: a Randomized Controlled Trial

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ClinicalTrials.gov 2025-09-02 Khyber Medical University Peshawar

ClinicalTrials.gov CLINICAL TRIAL psilocybin psilocin Depression Neuroplasticity Brain Imaging Randomized Controlled Trial More

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Evaluation of the Effect of a Single Dose of Psilocybin on Neural Correlates of Cognitive Control in Patients With Psychogenic Nonepileptic Seizures

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ClinicalTrials.gov 2025-08-21 Centre Hospitalier Universitaire de Nīmes

ClinicalTrials.gov CLINICAL TRIAL psilocybin Default Mode Network Emotional Processing Other More

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Effect of Psilocybin on the Positive Valence System in Treatment-resistant Depression: a Pilot Clinical Neuroimaging Study

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ClinicalTrials.gov 2025-08-20 Centre Hospitalier Universitaire de Nīmes

ClinicalTrials.gov CLINICAL TRIAL psilocybin psilocin Depression Brain Imaging Mechanism of Action Other More

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Effects of Psilocybin in Post-Treatment Lyme Disease

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ClinicalTrials.gov 2025-08-20 Johns Hopkins University

ClinicalTrials.gov CLINICAL TRIAL psilocybin General Other More

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A Phase II, Multicentre, Randomised, Double-blind, Controlled Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Efficacy of COMP360 in Participants With Recurrent Major Depressive Disorder

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ClinicalTrials.gov 2025-08-19 COMPASS Pathways

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Pharmacology Clinical Trial Clinical Trial More

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Modulation of Serotonin Pathways Using Psilocybin in Adults With and Without Autism Spectrum Disorder (ASD)

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ClinicalTrials.gov 2025-07-28 King's College London

ClinicalTrials.gov CLINICAL TRIAL psilocybin Brain Imaging Mechanism of Action Receptor Pharmacology Clinical Trial More

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The Safety, Feasibility, and Acceptability of Psilocybin Combined With Multidisciplinary Palliative Care in Demoralized Cancer Survivors With Chronic Pain (P-PC)

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ClinicalTrials.gov 2025-07-23 Emory University

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Anxiety End-of-Life Distress Clinical Trial More

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Visual Surround Suppression and Perceptual Expectation Under Psilocybin

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ClinicalTrials.gov 2025-06-27 University of Minnesota

ClinicalTrials.gov CLINICAL TRIAL psilocybin Mechanism of Action Other More

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The Safety and Tolerability of COMP360 in Participants With Post-traumatic Stress Disorder

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ClinicalTrials.gov 2025-06-13 COMPASS Pathways

ClinicalTrials.gov CLINICAL TRIAL psilocybin PTSD Safety Other More

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A Phase 1 Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Multiple Doses of MLS101 (Psilocybin) in Healthy Participants

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ClinicalTrials.gov 2025-06-12 MycoMedica Life Sciences PBC

ClinicalTrials.gov CLINICAL TRIAL psilocybin Pharmacology Microdosing Clinical Trial Clinical Trial More

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Comparison of the Effects of PEX20 (Oral Psilocin), PEX30 (Sublingual Psilocin), and PEX10 (Oral Psilocybin) in Healthy Adults

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ClinicalTrials.gov 2025-06-10 University of California, San Francisco

ClinicalTrials.gov CLINICAL TRIAL psilocybin psilocin Healthcare Workers Safety Other More

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Psilocybin With Intracranial Neural Sensing

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ClinicalTrials.gov 2025-06-06 Joshua Woolley, MD, PhD

ClinicalTrials.gov CLINICAL TRIAL psilocybin Chronic Pain Other More

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Low-Income Group Psilocybin Assisted Therapy for Depression: A Feasibility Study

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ClinicalTrials.gov 2025-06-05 Matthew Hicks

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Mechanism of Action Consciousness Clinical Trial More

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Optimizing Microdosing and Meditation

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ClinicalTrials.gov 2025-06-05 National University of Natural Medicine

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Addiction Consciousness Clinical Trial More

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Role of the Serotonin 2A Receptor in Psilocybin-induced Altered States of Consciousness (PDR-Study)

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ClinicalTrials.gov 2025-05-28 University Hospital, Basel, Switzerland

ClinicalTrials.gov CLINICAL TRIAL psilocybin psilocin Depression Anxiety Addiction Other More

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Psilocybin-facilitated Smoking Cessation Treatment: A Pilot Study

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ClinicalTrials.gov 2025-05-25 Johns Hopkins University

ClinicalTrials.gov CLINICAL TRIAL psilocybin Addiction Mechanism of Action Spirituality Randomized Controlled Trial More

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Consciousness and Psilocybin Effects on Well-Being (The CoPE Study): Pilot Phase

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ClinicalTrials.gov 2025-05-16 University of Wisconsin, Madison

ClinicalTrials.gov CLINICAL TRIAL psilocybin Consciousness Wellbeing Clinical Trial More

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Investigating the Role of Serotonin in the Mechanism of Action of Psilocybin in Patients With Major Depressive Disorder

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ClinicalTrials.gov 2025-05-14 Icahn School of Medicine at Mount Sinai

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Mechanism of Action Receptor Pharmacology Other More

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A Phase 2a, Open-label, Pilot Study to Assess the Safety and Efficacy of Psilocybin Administration in Concert With Psychotherapy Among Adult Patients With Fibromyalgia

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ClinicalTrials.gov 2025-04-16 Kevin Boehnke

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Anxiety Addiction Clinical Trial More

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The Role of Personal Experience for the Therapeutic Attitude in the Context of Substance-assisted Therapy Training

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ClinicalTrials.gov 2025-04-14 Felix Mueller

ClinicalTrials.gov CLINICAL TRIAL psilocybin Consciousness Safety Drug Interactions Other More