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Psilocybin and psilocin research index

Find psilocybin and psilocin papers, preprints, trials, and citations with clear source context.

Searches titles, authors, journals, identifiers, indexed metadata, and derived research topics. Use Filters to narrow by source, status, substance, study type, or date.

Database 4,959 indexed records Auto-updated on Aug 17, 2026 01:21 UTC

Executed search Sources: ClinicalTrials.gov 300 matching records are displayed.

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Database

4,740 Psilocybin Records 673 Psilocin Records 1,461 Journals 66 Research Topics

Published 4,221 Peer-reviewed / formal records Preprints 435 Marked as not peer reviewed Clinical trials 300 ClinicalTrials.gov records R toolkit visNetwork Bibliometrics, live SQLite analysis, HTML graph, and PDF export

Top journals 1,461 indexed journals

Journal	Records
Journal of psychopharmacology (Oxford, England)	147
Journal of psychoactive drugs	97
Frontiers in psychiatry	90
Psychopharmacology	85
Neuroscience Applied	57
Journal of Psychedelic Studies	48
Psychedelic medicine (New Rochelle, N.Y.)	39
Scientific reports	37
bioRxiv : the preprint server for biology	33
Biological Psychiatry	32

Research topics 66 topic filters

Depression 1,736 Receptor Pharmacology 1,282 Safety 1,201 Mechanism of Action 1,070 Review Article 1,070 Clinical Trial 975 Anxiety 882 Addiction 823 Pharmacology 753 General 537 Aging 524 Animal Study 524 Observational Study 515 Brain Imaging 481 Treatment-Resistant Depression 417 Emotional Processing 409 PTSD 400 Neuroplasticity 399

Source coverage 8 active sources

Source	Count	Share	Status
PubMed	2,567	51.8%	Active
OpenAlex	1,154	23.3%	Active
Crossref	404	8.1%	Active
ClinicalTrials.gov	300	6%	Active
Europe PMC	187	3.8%	Active
PsyArXiv	187	3.8%	Active
bioRxiv	122	2.5%	Active

Publication timeline 3,856 dated records

3,856 records since 2020

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Substances Psilocybin 4740 Psilocin 673

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Executed search Sources: ClinicalTrials.gov 300 matching records are displayed.

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300 matching records for Sources: ClinicalTrials.gov.

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PSilocybin for psYCHological and Existential Distress in PALliative Care (PSYCHED-PAL): A Multi-site, Open-label, Single Arm Phase I/II Proof-of-concept, Dose-finding, and Feasibility Clinical Trial

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ClinicalTrials.gov 2026-07-10 Ottawa Hospital Research Institute

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Anxiety End-of-Life Distress Randomized Controlled Trial More

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Investigating the Mechanisms of the Effects of Psilocybin on Visual Perception and Visual Representations in the Brain

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ClinicalTrials.gov 2026-07-10 University of California, Berkeley

ClinicalTrials.gov CLINICAL TRIAL psilocybin Brain Imaging Mechanism of Action Aging Other More

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The Effects of Psilocybin on Social Connectedness

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ClinicalTrials.gov 2026-07-09 Yale University

ClinicalTrials.gov CLINICAL TRIAL psilocybin Emotional Processing Clinical Trial More

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Psilocybin-Assisted Psychotherapy for Treatment-Resistant Depression: A Randomized Phase II Clinical Trial Comparing One Versus Two Psychedelic Doses of Psilocybin (PSI-1V2)

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ClinicalTrials.gov 2026-07-09 University Health Network, Toronto

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Clinical Trial Observational Study Clinical Trial More

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Computationally, Electrophysiologically, and Qualitatively Characterizing Serotonergic Psychedelics; Transdiagnostic Therapeutic and Pro-Psychotic Effects

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ClinicalTrials.gov 2026-07-09 Yale University

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression PTSD Addiction Clinical Trial More

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Psilocybin: Capturing Brain Mechanisms of Motivation and Neurocognition in Individuals With Opioid Use Disorder

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ClinicalTrials.gov 2026-07-09 University of Pennsylvania

ClinicalTrials.gov CLINICAL TRIAL psilocybin Addiction Brain Imaging Mechanism of Action Other More

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Phase I Study of the Safety and Adjunctive Effects of Psilocybin in Adults With Opioid Use Disorder Maintained on a Buprenorphine/Naloxone Formulation

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ClinicalTrials.gov 2026-07-07 University of Wisconsin, Madison

ClinicalTrials.gov CLINICAL TRIAL psilocybin Addiction Chronic Pain Clinical Trial Clinical Trial More

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Exploration of Synaptotrophic Effects of Psilocybin in Opioid Use Disorder (OUD)

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ClinicalTrials.gov 2026-07-07 Yale University

ClinicalTrials.gov CLINICAL TRIAL psilocybin Addiction Brain Imaging Aging Other More

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Consciousness and Psilocybin Effects on Well-Being: The CoPEWell Study

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ClinicalTrials.gov 2026-07-02 University of Wisconsin, Madison

ClinicalTrials.gov CLINICAL TRIAL psilocybin Consciousness Wellbeing Psychological Flexibility Other More

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Efficacy in Relapse Prevention: Psilocybin in Alcohol Use Disorder With Depressive Symptoms

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ClinicalTrials.gov 2026-07-01 Centre Hospitalier Universitaire de Nīmes

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Addiction Safety Other More

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A Phase 2, Open-Label Study Investigating the Safety and Efficacy of Psilocybin-Assisted Therapy for Sexual Assault-Related Posttraumatic Stress Disorder (PTSD)

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ClinicalTrials.gov 2026-07-01 Sunstone Medical

ClinicalTrials.gov CLINICAL TRIAL psilocybin PTSD Clinical Trial Safety Clinical Trial More

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5-HT2A Agonist Psilocybin in the Treatment of Tobacco Use Disorder

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ClinicalTrials.gov 2026-06-29 Johns Hopkins University

ClinicalTrials.gov CLINICAL TRIAL psilocybin Addiction Mechanism of Action Receptor Pharmacology Clinical Trial More

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Psilocybin-Assisted Massed Cognitive Processing Therapy for Chronic Posttraumatic Stress Disorder: An Open-label Trial

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ClinicalTrials.gov 2026-06-26 Unity Health Toronto

ClinicalTrials.gov CLINICAL TRIAL psilocybin PTSD Healthcare Workers Safety Other More

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Acute Effects of MDMA Co-administration on the Response to Psilocybin in Healthy Subjects

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ClinicalTrials.gov 2026-06-25 University Hospital, Basel, Switzerland

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Anxiety Addiction Qualitative Study More

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A Pilot Mechanistic RCT of Psilocybin With Mindfulness-based Therapy vs Support for Posttraumatic Stress Disorder (PTSD)

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ClinicalTrials.gov 2026-06-25 Anthony P King

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Anxiety PTSD Randomized Controlled Trial More

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Effects of Psilocybin Microdosing on Cognition, Mood and Quality of Life: A Pilot Study

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ClinicalTrials.gov 2026-06-23 Yale University

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Brain Imaging Mechanism of Action Other More

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Psilocybin-assisted Existential, Attachment and Relational (PEARL) Therapy for Caregivers of Patients With Advanced Cancer: A Phase II Open-Label Trial

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ClinicalTrials.gov 2026-06-23 University Health Network, Toronto

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Anxiety End-of-Life Distress Clinical Trial More

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Psilocybin-Assisted Therapy for Prolonged Grief

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ClinicalTrials.gov 2026-06-23 University of Virginia

ClinicalTrials.gov CLINICAL TRIAL psilocybin Brain Imaging Aging Spirituality Clinical Trial More

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Psilocybin for PTSD With or Without Psychotherapy: A Pilot Study of Safety and Efficacy

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ClinicalTrials.gov 2026-06-22 Johns Hopkins University

ClinicalTrials.gov CLINICAL TRIAL psilocybin PTSD Receptor Pharmacology Consciousness Randomized Controlled Trial More

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Psilocybin-assisted Existential, Attachment and RelationaL (PEARL) Therapy for Patients With Advanced Cancer: A Phase II Open-Label Trial

Abstract available at the source but not redistributed here. Read at source.

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ClinicalTrials.gov 2026-06-22 University Health Network, Toronto

ClinicalTrials.gov CLINICAL TRIAL psilocybin End-of-Life Distress Clinical Trial Safety Clinical Trial More