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Psilocybin and psilocin research index

Find psilocybin and psilocin papers, preprints, trials, and citations with clear source context.

Searches titles, authors, journals, identifiers, indexed metadata, and derived research topics. Use Filters to narrow by source, status, substance, study type, or date.

Database 4,959 indexed records Auto-updated on Aug 17, 2026 01:21 UTC

Executed search Sources: ClinicalTrials.gov 300 matching records are displayed.

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Database

4,740 Psilocybin Records 673 Psilocin Records 1,461 Journals 66 Research Topics

Published 4,221 Peer-reviewed / formal records Preprints 435 Marked as not peer reviewed Clinical trials 300 ClinicalTrials.gov records R toolkit visNetwork Bibliometrics, live SQLite analysis, HTML graph, and PDF export

Top journals 1,461 indexed journals

Journal	Records
Journal of psychopharmacology (Oxford, England)	147
Journal of psychoactive drugs	97
Frontiers in psychiatry	90
Psychopharmacology	85
Neuroscience Applied	57
Journal of Psychedelic Studies	48
Psychedelic medicine (New Rochelle, N.Y.)	39
Scientific reports	37
bioRxiv : the preprint server for biology	33
Biological Psychiatry	32

Research topics 66 topic filters

Depression 1,736 Receptor Pharmacology 1,282 Safety 1,201 Mechanism of Action 1,070 Review Article 1,070 Clinical Trial 975 Anxiety 882 Addiction 823 Pharmacology 753 General 537 Aging 524 Animal Study 524 Observational Study 515 Brain Imaging 481 Treatment-Resistant Depression 417 Emotional Processing 409 PTSD 400 Neuroplasticity 399

Source coverage 8 active sources

Source	Count	Share	Status
PubMed	2,567	51.8%	Active
OpenAlex	1,154	23.3%	Active
Crossref	404	8.1%	Active
ClinicalTrials.gov	300	6%	Active
Europe PMC	187	3.8%	Active
PsyArXiv	187	3.8%	Active
bioRxiv	122	2.5%	Active

Publication timeline 3,856 dated records

3,856 records since 2020

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Substances Psilocybin 4740 Psilocin 673

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Executed search Sources: ClinicalTrials.gov 300 matching records are displayed.

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300 matching records for Sources: ClinicalTrials.gov.

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A Phase 1 Translational Study to Assess Brain Activity Using Functional Magnetic Resonance Imaging (fMRI) and to Evaluate the Safety, Tolerability, and Pharmacokinetics of Multiple Doses of MLS101 (Psilocybin) in Healthy Volunteers

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ClinicalTrials.gov 2026-02-13 MycoMedica Life Sciences PBC

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Addiction Brain Imaging Clinical Trial More

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Psychedelic Healing: Adjunct Therapy Harnessing Opened Malleability

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ClinicalTrials.gov 2026-02-13 Johns Hopkins University

ClinicalTrials.gov CLINICAL TRIAL psilocybin Clinical Trial Animal Study Safety Clinical Trial More

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Psilocybin-assisted Therapy for Comorbid Major Depressive Disorder and Alcohol Use Disorder: A Pilot Randomized Clinical Trial

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ClinicalTrials.gov 2026-02-12 Centre for Addiction and Mental Health

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Addiction Clinical Trial Clinical Trial More

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Psilocybin-Assisted Cognitive Behavioral Therapy for Depression

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ClinicalTrials.gov 2026-02-12 University of California, Los Angeles

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Clinical Trial Clinical Trial More

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Safety and Psychological Effects of Psilocybin and D-Serine Formulation in Healthy Volunteers

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ClinicalTrials.gov 2026-02-05 Hadassah Medical Organization

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Anxiety Neuroplasticity Clinical Trial More

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A Phase 2a, Open-label, Pilot Study to Assess the Safety and Efficacy of Oral Psilocybin (TRP-8802) Administration in Concert With Psychotherapy Among Adult Patients With Irritable Bowel Syndrome: A Randomized Delayed Treatment Control Design

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ClinicalTrials.gov 2026-02-05 TRYP Therapeutics

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Anxiety Chronic Pain Clinical Trial More

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Psilocybin AsSisted pSychotherapy for the treatmENt of Gambling disordER: a Pilot Study

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ClinicalTrials.gov 2026-02-05 Nantes University Hospital

ClinicalTrials.gov CLINICAL TRIAL psilocybin Clinical Trial Safety Clinical Trial More

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A Phase 2 Trial of Psilocybin as an Adjunctive Treatment for OUD Patients Who Continue to Use Illicit Opioids Despite Adherence to Methadone Treatment

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ClinicalTrials.gov 2026-01-23 NYU Langone Health

ClinicalTrials.gov CLINICAL TRIAL psilocybin Addiction Clinical Trial Randomized Controlled Trial Randomized Controlled Trial More

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The STARLIGHT Protocol: State-Funded Trial Assessing Recovery and Long-Term Impact of Guided Psilocybin for Healing Trauma

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ClinicalTrials.gov 2026-01-22 Baylor College of Medicine

ClinicalTrials.gov CLINICAL TRIAL psilocybin PTSD Veterans Safety Other More

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Behavioral and Neural Mechanisms Supporting Psilocybin-assisted Therapy for Phantom Limb Pain

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ClinicalTrials.gov 2026-01-09 University of California, San Diego

ClinicalTrials.gov CLINICAL TRIAL psilocybin Chronic Pain Mechanism of Action Other More

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A Randomized Double-blinded Controlled Trial for the Treatment of Persisting Symptoms After Concussion With Psilocybin-assisted Therapy: A Safety and Feasibility Trial

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ClinicalTrials.gov 2025-12-30 University of Calgary

ClinicalTrials.gov CLINICAL TRIAL psilocybin Anxiety PTSD Headache / Migraine Randomized Controlled Trial More

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Microdosing Psychedelics to Improve Mood

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ClinicalTrials.gov 2025-12-30 Rotem Petranker

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Microdosing Clinical Trial Clinical Trial More

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The Safety and Efficacy of Psilocybin in Patients With Treatment-resistant Depression and Chronic Suicidal Ideation

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ClinicalTrials.gov 2025-12-24 Sheppard Pratt Health System

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Treatment-Resistant Depression Safety Other More

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An Open Label Study of Single-Dose Psilocybin for Major Depressive Disorder With Co-occurring Borderline Personality Disorder

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ClinicalTrials.gov 2025-12-23 University of Chicago

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Personality Change Safety Other More

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Effects of Psilocybin on Speech Fluency, Struggle, and Brain Activity in People Who Stutter

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ClinicalTrials.gov 2025-12-22 NYU Langone Health

ClinicalTrials.gov CLINICAL TRIAL psilocybin Mechanism of Action Wellbeing Clinical Trial Clinical Trial More

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Investigating the Effects of a Psychedelic-augmented Mental Imagery-based Intervention for Young People With Self-harm Behaviour: an Experimental Medicine Study

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ClinicalTrials.gov 2025-12-05 Imperial College London

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Mechanism of Action Emotional Processing Other More

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Standardized Natural Psilocybin-assisted Psychotherapy for Tapering of Opioid Medication in Patients With Chronic Pain: an Open-label Feasibility Study

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ClinicalTrials.gov 2025-12-04 University of British Columbia

ClinicalTrials.gov CLINICAL TRIAL psilocybin Addiction Chronic Pain Mechanism of Action Clinical Trial More

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A Phase 2b, Randomized, Double-blind, Placebo-controlled, Multi-center Study of the Effects of Psilocybin-assisted Psychotherapy on Psychiatric and Existential Distress in Advanced Cancer

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ClinicalTrials.gov 2025-12-04 NYU Langone Health

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Anxiety Mechanism of Action Randomized Controlled Trial More

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Psilocybin vs Ketamine for Alcohol Use Disorder

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ClinicalTrials.gov 2025-11-28 University of Iowa

ClinicalTrials.gov CLINICAL TRIAL psilocybin Addiction Clinical Trial More

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Digital Intervention for Psychedelic Preparation (DIPP): A Randomised Controlled Feasibility Trial Comparing Meditation and Music-Based Programs in Healthy Volunteers.

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ClinicalTrials.gov 2025-11-26 University College, London

ClinicalTrials.gov CLINICAL TRIAL psilocybin Mechanism of Action Consciousness Wellbeing Randomized Controlled Trial More