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Psilocybin and psilocin research index

Find psilocybin and psilocin papers, preprints, trials, and citations with clear source context.

Searches titles, authors, journals, identifiers, indexed metadata, and derived research topics. Use Filters to narrow by source, status, substance, study type, or date.

Database 4,967 indexed records Auto-updated on Aug 20, 2026 01:29 UTC

Executed search Topic: End-of-Life Distress 266 matching records are displayed.

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Database

4,748 Psilocybin Records 673 Psilocin Records 1,461 Journals 66 Research Topics

Published 4,226 Peer-reviewed / formal records Preprints 437 Marked as not peer reviewed Clinical trials 301 ClinicalTrials.gov records R toolkit visNetwork Bibliometrics, live SQLite analysis, HTML graph, and PDF export

Top journals 1,461 indexed journals

Journal	Records
Journal of psychopharmacology (Oxford, England)	148
Journal of psychoactive drugs	97
Frontiers in psychiatry	90
Psychopharmacology	85
Neuroscience Applied	57
Journal of Psychedelic Studies	48
Psychedelic medicine (New Rochelle, N.Y.)	39
Scientific reports	37
Biological Psychiatry	32
Journal of affective disorders	32

Research topics 66 topic filters

Depression 1,738 Receptor Pharmacology 1,282 Safety 1,208 Review Article 1,075 Mechanism of Action 1,072 Clinical Trial 978 Anxiety 884 Addiction 825 Pharmacology 752 General 538 Animal Study 525 Aging 524 Observational Study 516 Brain Imaging 482 Treatment-Resistant Depression 417 Emotional Processing 409 PTSD 401 Neuroplasticity 399

Source coverage 8 active sources

Source	Count	Share	Status
PubMed	2,566	51.7%	Active
OpenAlex	1,156	23.3%	Active
Crossref	407	8.2%	Active
ClinicalTrials.gov	301	6.1%	Active
Europe PMC	188	3.8%	Active
PsyArXiv	186	3.7%	Active
bioRxiv	124	2.5%	Active

Publication timeline 3,864 dated records

3,864 records since 2020

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Substances Psilocybin 4748 Psilocin 673

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Executed search Topic: End-of-Life Distress 266 matching records are displayed.

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266 matching records for Topic: End-of-Life Distress.

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Healthcare Providers' Perspectives on Psychedelic-Assisted Therapies Across Clinical Contexts: "I Can Offer Medical Assistance in Dying, but I Can't Prescribe Psychedelics".

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1177/27536130261459354 PubMed 42396366

Global advances in integrative medicine and health 2026-01-01 Schuman HDM, Mina R, Barkova S, Nguyen T, Deleemans JM, Carlson LE

PubMed Published psilocybin End-of-Life Distress Cancer Patients Toxicity Qualitative Study More

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Masking Influences: A Systematic Review of Placebo Control and Masking in Psychedelic Studies.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1080/02791072.2024.2424272 PubMed 39503404

Journal of psychoactive drugs 2026-01-01 Barstowe A, Kajonius PJ

PubMed Published psilocybin Depression Anxiety Addiction Systematic Review More

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Psychedelics as an intervention for psychological, existential distress in terminally ill patients: A systematic review and network meta-analysis.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1177/02698811241303594 PubMed 39655749

Journal of psychopharmacology (Oxford, England) 2026-01-01 Marchi M, Farina R, Rachedi K, Laonigro F, Žuljević MF, Pingani L

PubMed Published psilocybin Depression Anxiety End-of-Life Distress Randomized Controlled Trial More

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Psilocybin-assisted therapy for individuals with palliative care needs: A systematic review of safety and efficacy.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1177/02692163251383335 PubMed 41410211

Palliative medicine 2026-01-01 Matos ARS, Silva AC, Rego L, Fernandes R, Gonçalves S

PubMed Published psilocybin Depression Anxiety End-of-Life Distress Systematic Review More

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Stepping back into life: How Psychedelic Assisted Psychotherapy transforms the way of life of the terminally ill.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1016/j.genhosppsych.2025.12.002 PubMed 41418682

General hospital psychiatry 2026-01-01 Dwyer J, Johnston RB, O'Callaghan C, Ross M

PubMed Published psilocybin Anxiety End-of-Life Distress Clinical Trial Clinical Trial More

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Pharmacological Management of Anxiety in End-of-Life Care: A Systematic Review of Benzodiazepines, Opioids, and Psilocybin.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1002/hup.70032 PubMed 41502021

Human psychopharmacology 2026-01-01 Freitas da Costa B, Hartmann P, Pagnin D

PubMed Published psilocybin Anxiety Addiction End-of-Life Distress Systematic Review More

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Psychedelics and neuroanesthesia: A narrative review of converging mechanisms

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.65929/jsia.2026.1.2.002

Journal of Scientific Innovations in Anesthesiology 2025-12-31 Kunal Kumar Sharma

OpenAlex Published psilocybin Depression Anxiety PTSD Review Article More

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Effects of Serotonergic Psychedelics on Synaptic Function and Neuroplasticity

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.25593/open-fau-2619

OPUS FAU - Online publication system of Friedrich-Alexander-Universität Erlangen-Nürnberg 2025-12-31 Aneta Petrušková

OpenAlex Published psilocin Depression Anxiety Addiction Animal Study More

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Are Magic Mushrooms the Magic to Healing?

Abstract available at the source but not redistributed here. Read at source.

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DigitalCommons - Kennesaw State University (Kennesaw State University) 2025-12-07 Wohlfarth, Gale, Hardy, Susan, Ray, Herman

OpenAlex Published psilocybin Depression Anxiety PTSD Observational Study More

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Meaning and Purpose Therapy Modified for Psilocybin (P-MaP): A Treatment Model for Palliative Care Patients

No abstract availability was recorded for this entry.

Details DOI 10.1007/s42843-025-00145-3

Journal of Health Service Psychology 2025-12-01 Philip Garrity, Alicia Danforth, Brian Anderson, Jason M. Thompson

OpenAlex Published psilocybin End-of-Life Distress Chronic Pain Clinical Trial Clinical Trial More

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Efficacy of psilocybin on death anxiety in terminal patients: a narrative review

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1080/09699260.2026.2657096

Progress in Palliative Care 2025-11-30 Morris Lintong Barimbing, Dian Pritasari Jeger, Made Edwin Sridana

OpenAlex Published psilocybin Depression Anxiety End-of-Life Distress Randomized Controlled Trial More

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Pragmatic Trial of Psilocybin Therapy in Palliative Care (PT2PC): A Multicenter Triple-blind Phase 2 Randomized Controlled Trial of Psilocybin Therapy for Demoralized Adults Near the End of Life

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ClinicalTrials.gov 2025-11-25 Charles S. Grob, M.D.

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Anxiety End-of-Life Distress Randomized Controlled Trial More

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Open Label, Phase 2 Study for Evaluating the Feasibility, Safety and Efficacy of Psychotherapy Assisted Psilocybin for Treatment of Severe Obsessive Compulsive Disorder (OCD) in Drug and/or Psychotherapy Resistant Patients.

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ClinicalTrials.gov 2025-11-19 Beersheva Mental Health Center

ClinicalTrials.gov CLINICAL TRIAL psilocybin psilocin Depression Anxiety Addiction Clinical Trial More

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Psilocybin-assisted psychotherapy as a rapid-acting treatment for cancer-related depression and anxiety: Evidence from a network meta-analysis.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1177/00912174251337572 PubMed 40279353

International journal of psychiatry in medicine 2025-11-01 Swieczkowski D, Kwaśny A, Pruc M, Gaca Z, Szarpak L, Cubała WJ

PubMed Published psilocybin Depression Anxiety End-of-Life Distress Randomized Controlled Trial More

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Psilocybin-assisted Existential, Attachment and RelationaL (PEARL) therapy for patients with advanced cancer: protocol for a multi-method feasibility trial.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1186/s40814-025-01706-5 PubMed 41152967

Pilot and feasibility studies 2025-10-28 Richardson C, Chan C, Macgregor E, Hare C, Hannon B, Black S

PubMed Published psilocybin Depression End-of-Life Distress Clinical Trial Clinical Trial More

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Home-based psilocybin-assisted therapy for a patient with advanced cancer: A case report.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1017/s1478951525100941 PubMed 41127918

Palliative & supportive care 2025-10-23 Farzin H, Koren B, Ferrier H, Sanders JJ, Garel N

PubMed Published psilocybin Depression Anxiety End-of-Life Distress Case Report More

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Psychedelics in Practice: Science, Safety, and the Future of Healing

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.54389/epsd8792

The proceedings of sliit international conference on advancements in science and humanities 2025-10-09 Renee Ireland

OpenAlex Published psilocybin Depression Anxiety PTSD Other More

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Neurobiological and Therapeutic Potential of Psilocybin in Psychiatric Disorders

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.69613/thv1dn30

Journal of Pharma Insights and Research. 2025-10-05 M Loganathan, A Saravanakumar, P. Parthiban, G Anandharaj, S Gobika, D Dharshana

OpenAlex Published psilocybin psilocin Depression End-of-Life Distress Chronic Pain Clinical Trial More

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[Role of psychedelics in psychiatry: a true therapeutic revolution or a trend?].

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Details PubMed 41575100

La Revue du praticien 2025-10-01 Sabé M, Seragnoli F, Penzenstadler L, Thorens G

PubMed Published psilocybin Depression Anxiety PTSD Clinical Trial More

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Trauma under psychedelics: how psychoactive substances impact trauma processing

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Details DOI 10.1002/wps.21363 PubMed 40948086

World Psychiatry 2025-09-15 Ophir Netzer, Noa Magal, Yonatan Stern, Tzuk Polinsky, Raz Gross, Roee Admon

OpenAlex Published psilocybin PTSD Addiction End-of-Life Distress Observational Study More