Published

The quantitation of psilocybin in hallucinogenic mushrooms using high performance liquid chromatography.

A method using high performance liquid chromatography (HPLC) with an acetonitrile, water, and phosphoric acid mobile phase and a bonded cyano-amino-type polar phase column has been developed for the rapid, selective, and accurate quantitation of psilocybin in dry mushroom material. A simple one-step procedure is used for the quantitative extraction of psilocybin in under 60 min. The 267:254 nm absorbance ratio is used as a check on peak purity for the psilocybin response.

Open source BibTeX RIS

Bibliographic context

Journal: Unknown
Date: 1983-09-30
Source: Europe PMC
DOI: 10.1520/jfs11601j
PubMed: 6685168

Authors

Sottolano SM Lurie IS.

Watch author

Topics and keywords

psilocybin General Clinical Trial Basidiomycota Chromatography High Pressure Liquid Psilocybin

Citation graph

0 referenced DOIs found in stored source metadata. 0 indexed papers cite this DOI.

Open citation network

Related papers

Studies on enzymatic hydrolysis of psilocin- O -glucuronide for screening of psilocin in human urine by liquid chromatography-triple quadrupole tandem mass spectrometryJournal of Analytical Toxicology · 2026-05-26 Phase 1 trial suggests benefit of psilocybin in OCD treatmentThe Brown University Psychopharmacology Update · 2026-07-31 Surprising Variability in Tryptamine Profiles of Psilocybe cubensis Fruiting Bodies: Inter- and Intra-Strain Differences Across 14 Strains Cultivated Under Controlled ConditionsJournal of Fungi · 2026-07-01 Psilocybin helps woman with Alzheimer'sNew Scientist · 2026-06-30 Community engagement as a foundation for implementation research for group psilocybin assisted therapy in New MexicoFrontiers in Public Health · 2026-06-16 Rapid and Sensitive Detection of Psilocybin and Psilocin in Urine by Surface-Enhanced Raman SpectroscopyJournal of Raman Spectroscopy · 2026-05-27 Transient multidomain functional improvement in advanced Alzheimer’s disease following high-dose psilocybin-containing mushroom administration: a case reportFrontiers in Neuroscience · 2026-05-27 Long-Term Efficacy of Psilocybin with Adjunct Psychotherapy in Treatment-Resistant Major Depression (EPIsoDE): 6- and 12-Month Naturalistic Follow-Up of a Phase 2b TrialPsychotherapy and Psychosomatics · 2026-05-26