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Exploring Factors Affecting Psychological Flexibility After Psychedelic Experiences.

Neurobiological effects and psychological models propose that psychedelics may promote psychological flexibility, suggesting a transdiagnostic effect by disrupting maladaptive patterns. The objective of this study was therefore to investigate the determinants of psychological flexibility change following a psychedelic use. This retrospective online survey included French individuals who had undergone a significant psychedelic experience. Participants were assessed for mystical experience intensity with the MEQ-30, and psychological flexibility via the AAQ-II, at three retrospective time points. Data analysis comprised descriptive statistics, correlation analysis, ANCOVA to evaluate the impact of psychedelic use variables on psychological flexibility, and linear regression to identify predictors of psychological flexibility changes. Data showed a positive correlation between mystical experience intensity and improvements in psychological flexibility, especially 1-month post-experience (

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Bibliographic context

Journal: Journal of psychoactive drugs
Date: 2025-04-24
Source: PubMed
DOI: 10.1080/02791072.2025.2495937
PubMed: 40277080

Authors

Romeo B Kervadec E Fauvel B Strika-Bruneau L Amirouche A Verroust V Piolino P Benyamina A

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Topics and keywords

psilocybin Mystical Experience Psychological Flexibility Observational Study Observational Study LSD Psychedelic acceptance and commitment therapy psilocybin psychological flexibility

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