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Catatonia Associated With First-Time Psilocybin Exposure: A Case Report

In this case report, we highlight a 28-year-old male patient with predominantly retarded type of catatonia following a single incidence of psilocybin ingestion. This patient presented with a history of six months of mutism and inability to feed himself after consuming psilocybin for the first time. He did not have any history of psychiatric illness or substance use. Imaging and laboratory results were unremarkable. The goal of this case report is to document one of the earliest records of psilocybin-induced catatonia.

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Journal
Cureus
Date
2026-05-26
Source
OpenAlex
DOI
10.7759/cureus.c439
PubMed
42211293

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