Psilocybin-Research.comSearchable psilocybin and psilocin bibliometric database.
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Application overview

Source-labeled psilocybin and psilocin literature for search, monitoring, export, and citation workflows.

How the research index is built

Eight research sources feed Psilocybin-Research.com PubMed, OpenAlex, Crossref, Europe PMC, ClinicalTrials.gov, PsyArXiv, bioRxiv, and medRxiv provide records that are reconciled into the central research index. psilocybin-research.com PubMed OpenAlex Crossref Europe PMC ClinicalTrials.gov PsyArXiv bioRxiv medRxiv
Source records are fetched, reconciled, and labeled before appearing in the live index. The original sources remain authoritative.

Research workflow

Search, filter, export, analyze, and monitor publications with source labels, publication status, citation links, alerts, API access, and a rights-safe SQLite download. Read about the methods and limitations. Explore the dataset and reuse guide or research trends by year.

Open research · Psilocybin & psilocin

Countries and organisations

Explore psilocybin trials by country, sponsor and research facility. Compare registry status, study-start trends, conditions and mapped research sites.

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Explore registry geography and organisations

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26 trials match this view; 17 mapped facilities. Latest indexed registry check Oct 9, 2026 01:24 UTC. Country membership uses reported locations, including locations without coordinates; Mapped-facility counts cover all sites of matching trials, including international sites, and require valid coordinates.

Enrollment sum: 966 across 26 records with a reported count. Planned and actual counts are mixed; this is not a count of unique treated participants.

Recorded study-start years

200911
201311
201422
201511
201711
201922
202011
202111
202233
202344
202411
202566
202622

Current indexed registry status

Completed1717
Recruiting66
Not yet recruiting11
Active, not recruiting11
Withdrawn11

Reported research conditions

Counts describe indexed registry records, not efficacy or total research activity. A trial can count under several conditions or countries. Unknown dates are excluded from the start-year chart; future years reflect planned starts. Stopped studies may reflect recruitment, funding or strategy and are not automatically treatment failures.

Countries with reported trial locations

Canada4141

Sponsors recorded in this index

Matching trial records

26 matching registry records. Dates are registry milestones, not promised results announcements.
TrialSponsor and phaseStatusEnrollmentStart / primary completion / completionResearch workflow
PRISMatic: A Phase 1b Randomized, Double-Armed, Parallel-Group, Placebo-Controlled Trial of Psilocybin Efficacy With or Without Pimavanserin Pretreatment

NCT07610135

Mood (Psychological Function) · Well Being · Mood · Healthy
Johns Hopkins University

PHASE1, PHASE2

Recruiting

Registry updated 2026-10-01

20

ESTIMATED

2026-10-30
2028-06
2028-12
Activating Neuroplasticity to ENHANCE the Perception Box Expanding Effects of Psilocybin

NCT05866471

Healthy · Psychedelic Experiences · Vagus Nerve Stimulation
University of Wisconsin, Madison

PHASE1

Recruiting

Registry updated 2026-07-29

108

ESTIMATED

2025-01-27
2027-11
2028-01
Effects of Psilocybin on Electrophysiology and the Dynamic Content of Thought

NCT05301608

Healthy
Johns Hopkins University

PHASE1, PHASE2

Recruiting

Registry updated 2026-07-23

30

ESTIMATED

2022-03-03
2026-12-01
2027-01-01
Acute Effects of MDMA Co-administration on the Response to Psilocybin in Healthy Subjects

NCT06884514

Healthy
University Hospital, Basel, Switzerland

PHASE1

Completed

Registry updated 2026-06-25

24

ACTUAL

2025-04-03
2026-05-13
2026-05-28
The Acute Effects of Psilocybin on Cognition, Memory, and Brain Function

NCT07079852

Healthy
Manoj Doss

PHASE1, PHASE2

Not yet recruiting

Registry updated 2026-06-15

48

ESTIMATED

2026-09
2028-08
2028-08
Acute Analgesic Effects of DMT on Experimentally Induced Acute Nociceptive Pain, Hyperalgesia and Allodynia in Healthy Participants

NCT06180759

Healthy
University Hospital, Basel, Switzerland

PHASE1

Completed

Registry updated 2026-04-02

17

ACTUAL

2025-01-23
2025-09-29
2025-11-06
Digital Intervention for Psychedelic Preparation (DIPP): A Randomised Controlled Feasibility Trial Comparing Meditation and Music-Based Programs in Healthy Volunteers.

NCT06815653

Healthy
University College, London

PHASE1

Recruiting

Registry updated 2025-11-26

40

ESTIMATED

2025-03-01
2026-03
2026-12
Does Serotonin System Stimulation Increase Pro-social Behavior? - A Comparative Pharmacological Neuroscientific Study in Healthy Humans

NCT06081179

Healthy
University of Zurich

PHASE1

Completed

Registry updated 2025-11-19

122

ACTUAL

2023-10-24
2025-09-22
2025-09-22
Comparison of the Effects of PEX20 (Oral Psilocin), PEX30 (Sublingual Psilocin), and PEX10 (Oral Psilocybin) in Healthy Adults

NCT05317689

Healthy
University of California, San Francisco

PHASE1

Active, not recruiting

Registry updated 2025-06-10

20

ESTIMATED

2022-05-26
2025-01-16
2025-07
Role of the Serotonin 2A Receptor in Psilocybin-induced Altered States of Consciousness (PDR-Study)

NCT06796361

Healthy
University Hospital, Basel, Switzerland

PHASE1

Recruiting

Registry updated 2025-05-28

16

ESTIMATED

2025-04-21
2026-08
2026-08
Consciousness and Psilocybin Effects on Well-Being (The CoPE Study): Pilot Phase

NCT05592379

Healthy · Psychedelic Experiences · Sleep
University of Wisconsin, Madison

PHASE1

Completed

Registry updated 2025-05-16

6

ACTUAL

2023-11-07
2025-02-19
2025-02-19
Acute Dose-dependent Effects of DMT-bolus Applications in Healthy Subjects: A Placebo-controlled Cross-over Study (DMT BDR-Study).

NCT05695495

Healthy
University Hospital, Basel, Switzerland

PHASE1

Completed

Registry updated 2025-04-11

36

ACTUAL

2024-06-12
2025-02-02
2025-03-04
Direct Comparison of Altered States of Consciousness Induced by LSD, Psilocybin, and DMT in a Randomized, Placebo-controlled, Cross-over Trial in Healthy Participants (LPD-Study)

NCT06899334

Healthy
University Hospital, Basel, Switzerland

PHASE1

Recruiting

Registry updated 2025-03-27

24

ESTIMATED

2025-04-01
2026-08-01
2026-08-01
Acute Effects of 2C-B Compared With MDMA and Psilocybin in Healthy Subjects

NCT05523401

Healthy
University Hospital, Basel, Switzerland

PHASE1

Completed

Registry updated 2025-03-05

24

ACTUAL

2023-08-16
2024-10-20
2024-11-05
Effects of Psilocybin-facilitated Experience on the Psychology and Effectiveness of Professional Leaders in Religion

NCT02243813

Healthy
Johns Hopkins University

PHASE1

Completed

Registry updated 2024-06-18

24

ACTUAL

2015-03
2024-05-31
2024-05-31
Acute Dose-dependent Effects of DMT in Healthy Subjects: A Placebo-controlled Cross-over Study

NCT05384678

Healthy
University Hospital, Basel, Switzerland

PHASE1

Completed

Registry updated 2024-04-25

24

ACTUAL

2022-11-15
2024-03-08
2024-03-13
Comparative Acute Effects of LSD, Psilocybin and Mescaline in a Random-Order Placebo-Controlled Cross-Over Study in Healthy Subjects

NCT04227756

Healthy
University Hospital, Basel, Switzerland

PHASE1

Completed

Registry updated 2024-01-24

32

ACTUAL

2020-05-19
2022-09-02
2022-09-02
A Phase 1 Study Comparing the Pharmacokinetics and Safety of Intravenous and Oral Psilocybin

NCT05467761

Healthy
University of Wisconsin, Madison

PHASE1

Withdrawn

Registry updated 2023-05-15

0

ACTUAL

2023-06
2024-03
2024-03
Role of the Serotonin 5-HT2A Receptor in Mescaline-induced Altered States of Consciousness

NCT04849013

Healthy
University Hospital, Basel, Switzerland

PHASE1

Completed

Registry updated 2023-03-29

16

ACTUAL

2021-08-11
2023-03-27
2023-03-27
Direct Comparison of Altered States of Consciousness Induced by LSD and Psilocybin in a Random-order Placebo-controlled Cross-over Study in Healthy Subjects

NCT03604744

Healthy
University Hospital, Basel, Switzerland

EARLY_PHASE1

Completed

Registry updated 2021-04-27

28

ACTUAL

2019-03-27
2021-04-10
2021-04-15
Effects of Serotonin Transporter Inhibition on the Subjective Response to Psilocybin in Healthy Subjects

NCT03912974

Healthy
University Hospital, Basel, Switzerland

PHASE1

Completed

Registry updated 2020-12-01

27

ACTUAL

2019-07-04
2020-11-26
2020-11-26
Beyond the Self and Back: Neuropharmacological Mechanisms Underlying the Dissolution of the Self

NCT03736980

Healthy
University of Zurich

NA

Completed

Registry updated 2020-11-04

140

ACTUAL

2013-10-01
2018-12-31
2018-12-31
Pharmacokinetics of Psilocybin in Normal Adult Volunteers

NCT02163707

Healthy
University of Wisconsin, Madison

PHASE1

Completed

Registry updated 2020-04-15

12

ACTUAL

2014-06
2015-12
2015-12
Effects of Psilocybin on Behavior, Psychology and Brain Function in Long-term Meditators

NCT02145091

Healthy
Johns Hopkins University

PHASE1

Completed

Registry updated 2019-12-30

40

ACTUAL

2014-05
2019-12-26
2019-12-26
Measurement of Persisting Changes in Emotional Brain Functioning Produced by Psilocybin

NCT02971605

Healthy
Johns Hopkins University

PHASE1, PHASE2

Completed

Registry updated 2019-09-10

13

ACTUAL

2017-07-01
2018-08-21
2018-08-21
Effects of Psilocybin and Spiritual Practice on Persisting Changes in Attitudes and Behavior

NCT00802282

Healthy
Johns Hopkins University

PHASE1

Completed

Registry updated 2016-02-24

75

ACTUAL

2009-08
2014-02
2014-05

Reported research facilities

Johns Hopkins Center for Psychedelic and Consciousness ResearchBaltimore, Maryland, United States
University of Wisconsin - MadisonMadison, Wisconsin, United States
University Hospital BaselBasel, Switzerland
The University of Texas at Austin Dell Medical SchoolAustin, Texas, United States
Clinical Pharmacology & Toxicology, University Hospital BaselBasel, Switzerland
University College LondonLondon, United Kingdom
Psychiatrische Universitätsklinik ZürichZurich, Canton of Zurich, Switzerland
University of California, San FranciscoSan Francisco, California, United States
Clinical Trial UnitBasel, Canton of Basel-City, Switzerland
University of Wisconsin Hospital and ClinicsMadison, Wisconsin, United States
University HospitalBasel, Switzerland
Behavioral Biology Research Center, Johns Hopkins BayviewBaltimore, Maryland, United States
Universtity Hospital BaselBasel, Switzerland
University Hospital Basel, Clinical Trial UnitBasel, Canton of Basel-City, Switzerland
University of WisconsinMadison, Wisconsin, United States
University of Wisconsin, School of PharmacyMadison, Wisconsin, United States
Behavioral Pharmacology Research Unit, Johns Hopkins Bayview Medical CenterBaltimore, Maryland, United States

This list includes mapped sites of matching trials, including international sites; locations without usable coordinates are omitted. Facilities are registry-reported trial sites, not an independently verified clinic or research-centre directory. Current services and contact details must be checked at the source.