Open research · Psilocybin & psilocin

Countries and organisations

Explore psilocybin trials by country, sponsor and research facility. Compare registry status, study-start trends, conditions and mapped research sites.

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Explore registry geography and organisations

Trial, condition or NCT IDCountrySponsorPhaseStatusConditionReset

13 trials match this view; 20 mapped facilities. Latest indexed registry check Oct 9, 2026 01:24 UTC. Country membership uses reported locations, including locations without coordinates; Mapped-facility counts cover all sites of matching trials, including international sites, and require valid coordinates.

Enrollment sum: 878 across 13 records with a reported count. Planned and actual counts are mixed; this is not a count of unique treated participants.

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Recorded study-start years

202322

202422

202522

202677

Current indexed registry status

Recruiting66

Active, not recruiting44

Not yet recruiting11

Terminated11

Unknown status11

Reported research conditions

PTSD1313

PTSD - Post Traumatic Stress Disorder33

Post Traumatic Stress Disorder22

PTSD Symptoms22

Alcohol Use Disorder (AUD)22

OCD22

Chronic PTSD11

PTSD, Post Traumatic Stress Disorder11

Major Depression11

Suicidality11

Major Depressive Disorder (MDD)11

Healthy Volunteer11

Counts describe indexed registry records, not efficacy or total research activity. A trial can count under several conditions or countries. Unknown dates are excluded from the start-year chart; future years reflect planned starts. Stopped studies may reflect recruitment, funding or strategy and are not automatically treatment failures.

Countries with reported trial locations

United States182182

Canada4141

Switzerland2121

United Kingdom1818

France77

Denmark77

Netherlands66

Czechia55

Ireland55

Sweden44

Israel44

Germany33

Australia33

Spain22

Brazil22

Pakistan22

Portugal22

Belgium22

Poland11

Austria11

New Zealand11

Finland11

Jordan11

Jamaica11

Argentina11

Matching trial records

13 matching registry records. Dates are registry milestones, not promised results announcements.
Trial	Sponsor and phase	Status	Enrollment	Start / primary completion / completion
Psilocybin-Assisted Massed Cognitive Processing Therapy for Chronic Posttraumatic Stress Disorder: An Open-label Trial NCT06386003 Post Traumatic Stress Disorder · PTSD · Chronic PTSD	Unity Health Toronto PHASE2	Active, not recruiting Registry updated 2026-10-06	15 ESTIMATED	2026-06-01 2028-01 2028-06
A Phase 2b/3, Multicentre, Randomised, Double-blind, Controlled Trial, With an Open Label Extension, to Investigate the Efficacy, Safety, and Tolerability of COMP360 in Participants With Post-traumatic Stress Disorder NCT07570654 PTSD - Post Traumatic Stress Disorder · PTSD · PTSD Symptoms · PTSD, Post Traumatic Stress Disorder	COMPASS Pathways PHASE2, PHASE3	Recruiting Registry updated 2026-10-06	300 ESTIMATED	2026-09 2028-11 2029-09
The Safety and Acceptability of Psilocybin With Support and With Massed Prolonged Exposure Therapy for PTSD NCT07332143 PTSD	Emory University PHASE2	Recruiting Registry updated 2026-10-01	150 ESTIMATED	2026-06-08 2027-03 2027-03
PsiloStudy: A Phase 2 Single-site, Double-blind, Placebo-controlled, Randomized Clinical Trial With an Open-label Extension Phase to Examine the Safety, Subjective Experiences, Acute Effects, and Suitability of Psilocybin Combined With Psychological Support (Psi-PS) for Military Veterans and First Responders With Co-occurring Alcohol Use Disorder (AUD) and Posttraumatic Stress Disorder (PTSD) NCT06853912 Alcohol Use Disorder (AUD) · PTSD	Nathan Brashares Sackett PHASE2	Active, not recruiting Registry updated 2026-08-13	40 ESTIMATED	2025-06-01 2026-11-01 2027-06-01
Precision Phenotyping of Behavioral Risk and Response to Electromagnetic and Psychedelic Therapies NCT07745569 PTSD · PTSD - Post Traumatic Stress Disorder · Major Depression · Suicidality	University of New Mexico PHASE2	Not yet recruiting Registry updated 2026-08-04	150 ESTIMATED	2026-08-31 2030-06-30 2030-06-30
An Open-Label, Phase 1 Study of the Safety Pharmacokinetic Profile, and Preliminary Efficacy, of Organic Whole Psilocybin-Containing Mushrooms in Patients Suffering From PTSD NCT07275970 PTSD	Scottsdale Research Institute PHASE1	Active, not recruiting Registry updated 2026-07-29	24 ESTIMATED	2026-03-20 2026-07-30 2026-10-01
Computationally, Electrophysiologically, and Qualitatively Characterizing Serotonergic Psychedelics; Transdiagnostic Therapeutic and Pro-Psychotic Effects NCT06624137 OCD · Major Depressive Disorder (MDD) · Alcohol Use Disorder (AUD) · Healthy Volunteer · Migraine · PTSD · PTSD - Post Traumatic Stress Disorder · Addiction · Tobacco Use Disorder · Obsessive Compulsive Disorder (OCD) · Opioid Use Disorder	Yale University Phase not reported	Terminated Registry updated 2026-07-09	5 ACTUAL	2024-12-12 2026-06-14 2026-06-14
A Phase 2, Open-Label Study Investigating the Safety and Efficacy of Psilocybin-Assisted Therapy for Sexual Assault-Related Posttraumatic Stress Disorder (PTSD) NCT06902974 Post Traumatic Stress Disorder · PTSD	Sunstone Medical PHASE2	Recruiting Registry updated 2026-07-01	70 ESTIMATED	2026-05-23 2027-11 2028-05
Group Psilocybin-Assisted Therapy for Post-Traumatic Stress Disorder NCT07506395 PTSD	University of New Mexico PHASE1	Recruiting Registry updated 2026-05-22	36 ESTIMATED	2026-05-01 2027-05-01 2028-05-01
Safety, Feasibility, and Tolerability of Psilocybin Treatment for Individuals With Functional Impairment Related to Mood, Anxiety, Trauma and/or Addiction Symptoms: An Open-label Proof-of-concept Study NCT06442423 Transdiagnostic · Depression - Major Depressive Disorder · Anxiety · PTSD Symptoms · PTSD · Substance Use · Substance Use Disorder (SUD) · OCD	Yale University PHASE1	Recruiting Registry updated 2026-03-11	50 ESTIMATED	2024-10-17 2027-12 2027-12
Examining the Safety and Clinical Efficacy of Psilocybin Therapy for Veterans With PTSD: An Open-Label Proof-of-Concept Trial NCT05554094 PTSD · Stress Disorders, Traumatic · Stress Disorders, Post-Traumatic · Trauma and Stressor Related Disorders · Mental Disorder	Ohio State University PHASE2	Active, not recruiting Registry updated 2026-03-04	15 ESTIMATED	2023-01-01 2025-12-31 2026-07-31
The STARLIGHT Protocol: State-Funded Trial Assessing Recovery and Long-Term Impact of Guided Psilocybin for Healing Trauma NCT06888128 PTSD	Baylor College of Medicine PHASE2	Recruiting Registry updated 2026-01-22	15 ESTIMATED	2025-01-30 2026-12-15 2026-12-15
Evaluation of the Acceptability, Safety, Feasibility, and Efficacy of Psilocybin-assisted Psychotherapy (PaP) for the Treatment of Post-traumatic Stress Disorder (PTSD) in Military Veterans NCT05876481 PTSD	Combat Stress PHASE2	Unknown status Registry updated 2023-05-25	8 ESTIMATED	2023-06 2025-07 2025-08

Reported research facilities

St. Michael's Hospital, Unity Health TorontoToronto, Ontario, Canada

FLMiami, Florida, United States

FLOrlando, Florida, United States

ILChicago, Illinois, United States

MNEden Prairie, Minnesota, United States

NELincoln, Nebraska, United States

NVLas Vegas, Nevada, United States

NYNew York, New York, United States

BCNorth Vancouver, British Columbia, Canada

Emory University HospitalAtlanta, Georgia, United States

University of Washington Center for Novel Therapeutics in Addiction PsychiatrySeattle, Washington, United States

Scottsdale Research InstituteScottsdale, Arizona, United States

Connecticut Mental Health CenterHamden, Connecticut, United States

West Haven VA Medical CenterWest Haven, Connecticut, United States

Sunstone Medical, PCRockville, Maryland, United States

Interdisciplinary Substance Use and Brain Injury (ISUBI)Albuquerque, New Mexico, United States

Connecticut Mental Health Center - Yale School of MedicineNew Haven, Connecticut, United States

Ohio State University Department of Psychiatry and Behavioral Health at the Davis Medical Research CenterColumbus, Ohio, United States

Baylor College of MedicineHouston, Texas, United States

Combat StressLeatherhead, Surrey, United Kingdom

This list includes mapped sites of matching trials, including international sites; locations without usable coordinates are omitted. Facilities are registry-reported trial sites, not an independently verified clinic or research-centre directory. Current services and contact details must be checked at the source.