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Psilocybin and psilocin research index

Find psilocybin and psilocin papers, preprints, trials, and citations with clear source context.

Searches titles, authors, journals, identifiers, indexed metadata, and derived research topics. Use Filters to narrow by source, status, substance, study type, or date.

Database 4,980 indexed records Auto-updated on Aug 27, 2026 01:25 UTC

Executed search Author: Robin Carhart-Harris 186 matching records are displayed.

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Database

4,761 Psilocybin Records 674 Psilocin Records 1,464 Journals 66 Research Topics

Published 4,235 Peer-reviewed / formal records Preprints 441 Marked as not peer reviewed Clinical trials 301 ClinicalTrials.gov records R toolkit visNetwork Bibliometrics, live SQLite analysis, HTML graph, and PDF export

Top journals 1,464 indexed journals

Journal	Records
Journal of psychopharmacology (Oxford, England)	150
Journal of psychoactive drugs	97
Frontiers in psychiatry	90
Psychopharmacology	85
Neuroscience Applied	57
Journal of Psychedelic Studies	48
Psychedelic medicine (New Rochelle, N.Y.)	39
Scientific reports	37
Biological Psychiatry	32
Journal of affective disorders	32

Research topics 66 topic filters

Depression 1,742 Receptor Pharmacology 1,284 Safety 1,213 Review Article 1,076 Mechanism of Action 1,075 Clinical Trial 982 Anxiety 887 Addiction 827 Pharmacology 753 General 539 Animal Study 527 Aging 526 Observational Study 518 Brain Imaging 483 Treatment-Resistant Depression 417 Emotional Processing 410 Neuroplasticity 401 PTSD 401

Source coverage 8 active sources

Source	Count	Share	Status
PubMed	2,566	51.5%	Active
OpenAlex	1,156	23.2%	Active
Crossref	408	8.2%	Active
ClinicalTrials.gov	301	6%	Active
Europe PMC	198	4%	Active
PsyArXiv	186	3.7%	Active
bioRxiv	125	2.5%	Active

Publication timeline 3,877 dated records

3,877 records since 2020

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Keyword search Author

Substances Psilocybin 4761 Psilocin 674

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Executed search Author: Robin Carhart-Harris 186 matching records are displayed.

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186 matching records for Author: Robin Carhart-Harris.

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The effects of psilocybin therapy versus escitalopram on cognitive bias: A secondary analysis of a randomized controlled trial

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1101/2025.03.17.25324123

medRxiv 2025-03-21 Henry J, Giribaldi B, Nutt DJ, Erritzoe D, Carhart-Harris R, Lyons T.

medRxiv PREPRINT (not peer reviewed) psilocybin Depression Randomized Controlled Trial Randomized Controlled Trial More

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Revealing Changes in Linear and Nonlinear Functional Connectivity After Psilocybin and Escitalopram Treatment in Patients with Depression

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1101/2025.03.05.641592

bioRxiv 2025-03-10 Quah S, Glick C, Roseman L, Pasquini L, Carhart-Harris R, Saggar M.

bioRxiv PREPRINT (not peer reviewed) psilocybin Depression Brain Imaging Mechanism of Action Other More

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The role of the psychedelic experience in psilocybin treatment for treatment-resistant depression.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1016/j.jad.2024.12.061 PubMed 39706482

Journal of affective disorders 2025-03-01 Goodwin GM, Aaronson ST, Alvarez O, Carhart-Harris R, Chai-Rees J, Croal M

PubMed Published psilocybin Depression Pharmacology Mechanism of Action Clinical Trial More

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A Field-Wide Review and Analysis of Study Materials Used in Psilocybin Trials: Assessment of Two Decades of Research.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1089/psymed.2024.0019 PubMed 40351554

Psychedelic medicine (New Rochelle, N.Y.) 2025-03-01 Yaden DB, Graziosi M, Owen AM, Agin-Liebes G, Aaronson ST, Allen KE

PubMed Published psilocybin Receptor Pharmacology Consciousness Wellbeing Review Article More

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A qualitative analysis of the psychedelic mushroom come-up and come-down.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1038/s44184-024-00095-6 PubMed 39915687

Npj mental health research 2025-02-07 Brouwer A, Brown JK, Erowid E, Erowid F, Thyssen S, Raison CL

PubMed Published psilocybin Consciousness Clinical Trial Clinical Trial More

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Examining differences in the effects and contexts of naturalistic psilocybin use for White participants vs. Participants of Color: A longitudinal online survey study.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1016/j.jad.2024.10.058 PubMed 39447981

Journal of affective disorders 2025-02-01 Jones G, Lowe MX, Nayak S, Sepeda N, Kettner H, Carhart-Harris R

PubMed Published psilocybin Depression Anxiety Biomarkers Observational Study More

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From relaxed beliefs under psychedelics (REBUS) to revised beliefs after psychedelics (REBAS).

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1038/s41598-023-28111-3 PubMed 39881126

Scientific reports 2025-01-29 Zeifman RJ, Spriggs MJ, Kettner H, Lyons T, Rosas FE, Mediano PAM

PubMed Published psilocybin Brain Imaging Wellbeing Other More

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Perturbing whole-brain models of brain hierarchy: an application for depression following pharmacological treatment

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1101/2025.01.01.631011

bioRxiv 2025-01-02 Socoró Garrigosa M, Sanz Perl Y, Kringelbach ML, Carhart-Harris R, Vohryzek J, Deco G.

bioRxiv PREPRINT (not peer reviewed) psilocybin Depression Neuroplasticity Clinical Trial Clinical Trial More

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Effects of escitalopram and psilocybin therapy on mesolimbic resting-state functional connectivity in depression

No abstract availability was recorded for this entry.

Details DOI 10.1016/j.nsa.2025.105421

Neuroscience Applied 2025-01-01 Rebecca Harding, Natalie Ertl, Rabia Zafar, Magnus Wall, Rajkanya Das, David Erritzøe

OpenAlex Published psilocybin Depression Brain Imaging Other More

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Human neuroimaging: fMRI.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1016/bs.irn.2025.04.013 PubMed 40541308

International review of neurobiology 2025-01-01 Wall MB, Carhart-Harris RL

PubMed Published psilocybin Brain Imaging Pharmacology Aging Observational Study More

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An investigation of acute physiological and psychological moderators of psychedelic-induced personality change among healthy volunteers.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1016/j.nsa.2024.104092 PubMed 40654586

Neuroscience applied 2025-01-01 Godfrey K, Weiss B, Zhang X, Spriggs M, Peill J, Lyons T

PubMed Published psilocybin Consciousness Personality Change Healthy Volunteers Other More

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Study Protocol for 'PsilOCD: A Pharmacological Challenge Study Evaluating the Effects of the 5-HT2A Agonist Psilocybin on the Neurocognitive and Clinical Correlates of Compulsivity'.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.7759/cureus.78171 PubMed 39882198

Cureus 2025-01-01 O'Connor S, Godfrey K, Reed S, Peill J, Rohani-Shukla C, Healy M

PubMed Published psilocybin OCD Neuroplasticity Brain Imaging Other More

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Correction: Study Protocol for 'PsilOCD: A Pharmacological Challenge Study Evaluating the Effects of the 5-HT2A Agonist Psilocybin on the Neurocognitive and Clinical Correlates of Compulsivity'.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.7759/cureus.c209 PubMed 39897296

Cureus 2025-01-01 O'Connor S, Godfrey K, Reed S, Peill J, Rohani-Shukla C, Healy M

PubMed Published psilocybin OCD Receptor Pharmacology Other More

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Enhanced meaning in life following psychedelic use: converging evidence from controlled and naturalistic studies.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.3389/fpsyg.2025.1580663 PubMed 40547590

Frontiers in psychology 2025-01-01 Roseby W, Kettner H, Roseman L, Spriggs MJ, Lyons T, Peill J

PubMed Published psilocybin Depression Mechanism of Action Wellbeing Clinical Trial More

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Improved mental health outcomes and normalised spontaneous EEG activity in veterans reporting a history of traumatic brain injuries following participation in a psilocybin retreat.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.3389/fpsyt.2025.1594307 PubMed 40842948

Frontiers in psychiatry 2025-01-01 Blest-Hopley G, Pasculli G, Ruffell SGD, Tsang W, Emmanuel O, Pate KM

PubMed Published psilocybin Depression PTSD Neuroplasticity Other More

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Brain dynamics of classical psychedelics show paradoxical hierarchical flattening with increased complexity

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Details DOI 10.1101/2024.12.21.629922

bioRxiv 2024-12-22 Vohryzek J, Garcia Guzman E, Kringelbach ML, Lopez-Sola E, Timmermann C, Roseman L

bioRxiv PREPRINT (not peer reviewed) psilocybin Consciousness Drug Interactions Other More

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Synergistic, multi-level understanding of psychedelics: three systematic reviews and meta-analyses of their pharmacology, neuroimaging and phenomenology.

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Details DOI 10.1038/s41398-024-03187-1 PubMed 39632810

Translational psychiatry 2024-12-04 Shinozuka K, Jerotic K, Mediano P, Zhao AT, Preller KH, Carhart-Harris R

PubMed Published psilocybin psilocin Depression Addiction Brain Imaging Systematic Review More

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Long-term effects of psilocybin on dynamic and effectivity connectivity of fronto-striatal-thalamic circuits

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1101/2024.11.06.622302

bioRxiv 2024-11-07 Pasquini L, Vohryzek J, Escrichs A, Sanz Perl Y, Ponce-Alvarez A, Idesis S

bioRxiv PREPRINT (not peer reviewed) psilocybin Depression Eating Disorders Brain Imaging Other More

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Preliminary Evidence of Sleep Improvements Following Psilocybin Administration, and their Involvement in Antidepressant Therapeutic Action.

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Details DOI 10.1007/s11920-024-01539-8 PubMed 39532819

Current psychiatry reports 2024-11-01 Reid MJ, Kettner H, Blanken TF, Weiss B, Carhart-Harris R

PubMed Published psilocybin Depression Mechanism of Action Clinical Trial Clinical Trial More

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Human brain changes after first psilocybin use

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1101/2024.10.11.617955

bioRxiv 2024-10-14 Lyons T, Spriggs M, Kerkelä L, Rosas F, Roseman L, Mediano P

bioRxiv PREPRINT (not peer reviewed) psilocybin Brain Imaging Aging Wellbeing Other More