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Psilocybin and psilocin research index

Find psilocybin and psilocin papers, preprints, trials, and citations with clear source context.

Searches titles, authors, journals, identifiers, indexed metadata, and derived research topics. Use Filters to narrow by source, status, substance, study type, or date.

Database 4,961 indexed records Auto-updated on Aug 19, 2026 01:24 UTC

Executed search Cites DOI: 10.1001/jamapsychiatry.2020.3285 49 matching records are displayed.

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Database

4,742 Psilocybin Records 673 Psilocin Records 1,461 Journals 66 Research Topics

Published 4,223 Peer-reviewed / formal records Preprints 435 Marked as not peer reviewed Clinical trials 300 ClinicalTrials.gov records R toolkit visNetwork Bibliometrics, live SQLite analysis, HTML graph, and PDF export

Top journals 1,461 indexed journals

Journal	Records
Journal of psychopharmacology (Oxford, England)	148
Journal of psychoactive drugs	97
Frontiers in psychiatry	90
Psychopharmacology	85
Neuroscience Applied	57
Journal of Psychedelic Studies	48
Psychedelic medicine (New Rochelle, N.Y.)	39
Scientific reports	37
Biological Psychiatry	32
Journal of affective disorders	32

Research topics 66 topic filters

Depression 1,737 Receptor Pharmacology 1,281 Safety 1,203 Mechanism of Action 1,072 Review Article 1,072 Clinical Trial 977 Anxiety 883 Addiction 824 Pharmacology 752 General 538 Aging 524 Animal Study 524 Observational Study 515 Brain Imaging 481 Treatment-Resistant Depression 417 Emotional Processing 409 PTSD 400 Neuroplasticity 399

Source coverage 8 active sources

Source	Count	Share	Status
PubMed	2,566	51.7%	Active
OpenAlex	1,155	23.3%	Active
Crossref	405	8.2%	Active
ClinicalTrials.gov	300	6%	Active
Europe PMC	188	3.8%	Active
PsyArXiv	186	3.7%	Active
bioRxiv	123	2.5%	Active

Publication timeline 3,858 dated records

3,858 records since 2020

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Substances Psilocybin 4742 Psilocin 673

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Executed search Cites DOI: 10.1001/jamapsychiatry.2020.3285 49 matching records are displayed.

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49 matching records for Cites DOI: 10.1001/jamapsychiatry.2020.3285.

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Psilocybin and psilocin regulate microglial immunomodulation and support neuroplasticity via serotonergic and AhR signaling

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1016/j.intimp.2025.114940 PubMed 40424654

International Immunopharmacology 2025-06-01 Laabi Salma, LeMmon Claire, Vogel Callie, Chacon Mariana, Jimenez Victor M.

Crossref Published psilocybin psilocin Neuroplasticity Mechanism of Action Other More

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Determination of psilocybin and psilocin content in multiple Psilocybe cubensis mushroom strains using liquid chromatography - tandem mass spectrometry

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1016/j.aca.2023.342161 PubMed 38220293

Analytica Chimica Acta 2024-02-01 Goff Roman, Smith Morgan, Islam Sabrina, Sisley Sue, Ferguson Jonathan, Kuzdzal Scott

Crossref Published psilocybin psilocin General Other More

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In vivo validation of psilacetin as a prodrug yielding modestly lower peripheral psilocin exposure than psilocybin

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.3389/fpsyt.2023.1303365 PubMed 38264637

Frontiers in Psychiatry 2024-01-08 Jones Nathan T., Wagner Laura, Hahn Molly C. Pellitteri, Scarlett Cameron O., Wenthur Cody J.

Crossref Published psilocybin psilocin Mechanism of Action Animal Study Animal Study More

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Visualizing drug actions on dendrites: psilocybin and other classic psychedelics

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1364/brain.2023.btu2b.2

Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN) 2023-01-01 Shao Ling-Xiao, Liao Clara, Gregg Ian, Davoudian Pasha A, Savalia Neil K, Delagarza Kristina

Crossref Published psilocybin Animal Study Animal Study More

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Direct Quantitation of Psilocybin and Psilocin by One-Dimensional 1H and 31P qNMR in a revived Greek specimen of Psilocybe cyanescens

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1055/s-0042-1759062

Planta Medica 2022-12-01 Magiatis P, Dadiotis E, Antonopoulos R K, Ioannidis K, Mitsis V, Melliou E

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Psilocybin modulation of time-varying functional connectivity is associated with plasma psilocin and subjective effects

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Details DOI 10.1016/j.neuroimage.2022.119716 PubMed 36341951

NeuroImage 2022-12-01 Olsen Anders S., Lykkebo-Valløe Anders, Ozenne Brice, Madsen Martin K., Stenbæk Dea S., Armand Sophia

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Psilocin acutely alters sleep-wake architecture and cortical brain activity in laboratory mice

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Details DOI 10.1038/s41398-022-01846-9 PubMed 35197453

Translational Psychiatry 2022-02-23 Thomas Christopher W., Blanco-Duque Cristina, Bréant Benjamin J., Goodwin Guy M., Sharp Trevor, Bannerman David M.

Crossref Published psilocin Depression Neuroplasticity Brain Imaging Animal Study More

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Psilocybin-induced changes in brain network integrity and segregation correlate with plasma psilocin level and psychedelic experience

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1016/j.euroneuro.2021.06.001 PubMed 34246868

European Neuropsychopharmacology 2021-09-01 Madsen Martin K., Stenbæk Dea S., Arvidsson Albin, Armand Sophia, Marstrand-Joergensen Maja R., Johansen Sys S.

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Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder: A Randomized Clinical Trial.

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Details DOI 10.1001/jamapsychiatry.2020.3285 PubMed 33146667

JAMA psychiatry 2021-05-01 Davis AK, Barrett FS, May DG, Cosimano MP, Sepeda ND, Johnson MW

PubMed Published psilocybin Depression Consciousness Clinical Trial Clinical Trial More