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Psilocybin and psilocin research index

Find psilocybin and psilocin papers, preprints, trials, and citations with clear source context.

Searches titles, authors, journals, identifiers, indexed metadata, and derived research topics. Use Filters to narrow by source, status, substance, study type, or date.

Database 4,961 indexed records Auto-updated on Aug 19, 2026 01:24 UTC

Executed search Journal: International journal of molecular sciences 17 matching records are displayed.

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Database

4,742 Psilocybin Records 673 Psilocin Records 1,461 Journals 66 Research Topics

Published 4,223 Peer-reviewed / formal records Preprints 435 Marked as not peer reviewed Clinical trials 300 ClinicalTrials.gov records R toolkit visNetwork Bibliometrics, live SQLite analysis, HTML graph, and PDF export

Top journals 1,461 indexed journals

Journal	Records
Journal of psychopharmacology (Oxford, England)	148
Journal of psychoactive drugs	97
Frontiers in psychiatry	90
Psychopharmacology	85
Neuroscience Applied	57
Journal of Psychedelic Studies	48
Psychedelic medicine (New Rochelle, N.Y.)	39
Scientific reports	37
Biological Psychiatry	32
Journal of affective disorders	32

Research topics 66 topic filters

Depression 1,737 Receptor Pharmacology 1,281 Safety 1,203 Mechanism of Action 1,072 Review Article 1,072 Clinical Trial 977 Anxiety 883 Addiction 824 Pharmacology 752 General 538 Aging 524 Animal Study 524 Observational Study 515 Brain Imaging 481 Treatment-Resistant Depression 417 Emotional Processing 409 PTSD 400 Neuroplasticity 399

Source coverage 8 active sources

Source	Count	Share	Status
PubMed	2,566	51.7%	Active
OpenAlex	1,155	23.3%	Active
Crossref	405	8.2%	Active
ClinicalTrials.gov	300	6%	Active
Europe PMC	188	3.8%	Active
PsyArXiv	186	3.7%	Active
bioRxiv	123	2.5%	Active

Publication timeline 3,858 dated records

3,858 records since 2020

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Substances Psilocybin 4742 Psilocin 673

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Executed search Journal: International journal of molecular sciences 17 matching records are displayed.

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17 matching records for Journal: International journal of molecular sciences.

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Beyond the Genomic Storm: Evaluating Tabernanthalog as a Potential Scaffold for Silent Neuroplasticity and Broad-Spectrum Therapy.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.3390/ijms27062811 PubMed 41898671

International journal of molecular sciences 2026-03-20 Anchesi I, Raffaele I, Astorino MF, Lui M, Calabrò M, Cipriano GL

PubMed Published psilocybin End-of-Life Distress Chronic Pain Neuroplasticity Review Article More

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Microdosing Psychedelics to Restore Synaptic Density in Schizophrenia.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.3390/ijms26188949 PubMed 41009515

International journal of molecular sciences 2025-09-14 Sapienza J, Spangaro M, Comai S, Sabé M, La Torre J, Buonarroti M

PubMed Published psilocybin Neuroplasticity Aging Microdosing Animal Study More

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Substance Abuse and Cognitive Decline: The Critical Role of Tau Protein as a Potential Biomarker.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.3390/ijms26157638 PubMed 40806766

International journal of molecular sciences 2025-08-07 Rebolledo-Pérez L, Hernández-Bello J, Martínez-Ramos A, Castañeda-Arellano R, Fernández-Quezada D, Sandoval-García F

PubMed Published psilocybin Addiction Neuroplasticity Mechanism of Action Review Article More

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Molecular Pathways Potentially Involved in Hallucinatory Experiences During Sleep Paralysis: The Emerging Role of β-Arrestin-2.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.3390/ijms26157233 PubMed 40806366

International journal of molecular sciences 2025-07-26 Rudy LM, Godlewski MM

PubMed Published psilocybin Mechanism of Action Receptor Pharmacology Consciousness Review Article More

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Molecular and Medical Aspects of Psychedelics.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.3390/ijms25010241 PubMed 38203411

International journal of molecular sciences 2023-12-23 Wojtas A, Gołembiowska K

PubMed Published psilocybin Depression Anxiety Addiction Review Article More

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A Brief Review on the Potential of Psychedelics for Treating Alzheimer's Disease and Related Depression.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.3390/ijms241512513 PubMed 37569888

International journal of molecular sciences 2023-08-07 Pilozzi A, Foster S, Mischoulon D, Fava M, Huang X

PubMed Published psilocybin Depression Mechanism of Action Receptor Pharmacology Review Article More

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The Bright Side of Psychedelics: Latest Advances and Challenges in Neuropharmacology.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.3390/ijms24021329 PubMed 36674849

International journal of molecular sciences 2023-01-10 Mastinu A, Anyanwu M, Carone M, Abate G, Bonini SA, Peron G

PubMed Published psilocybin psilocin Depression PTSD OCD Review Article More

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Psychedelic-Induced Serotonin 2A Receptor Downregulation Does Not Predict Swim Stress Coping in Mice.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.3390/ijms232315284 PubMed 36499610

International journal of molecular sciences 2022-12-04 Pędzich BD, Medrano M, Buckinx A, Smolders I, De Bundel D

PubMed Published psilocybin Depression Receptor Pharmacology Animal Study Animal Study More

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Role of 5-HT2A, 5-HT2C, 5-HT1A and TAAR1 Receptors in the Head Twitch Response Induced by 5-Hydroxytryptophan and Psilocybin: Translational Implications.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.3390/ijms232214148 PubMed 36430623

International journal of molecular sciences 2022-11-16 Shahar O, Botvinnik A, Esh-Zuntz N, Brownstien M, Wolf R, Lotan A

PubMed Published psilocybin Receptor Pharmacology Animal Study Animal Study More

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Extensive Collection of Psychotropic Mushrooms with Determination of Their Tryptamine Alkaloids.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.3390/ijms232214068 PubMed 36430546

International journal of molecular sciences 2022-11-15 Gotvaldová K, Borovička J, Hájková K, Cihlářová P, Rockefeller A, Kuchař M

PubMed Published psilocybin psilocin Microdosing Safety Other More

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Esketamine and Psilocybin-The Comparison of Two Mind-Altering Agents in Depression Treatment: Systematic Review.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.3390/ijms231911450 PubMed 36232748

International journal of molecular sciences 2022-09-28 Psiuk D, Nowak EM, Dycha N, Łopuszańska U, Kurzepa J, Samardakiewicz M

PubMed Published psilocybin Depression Systematic Review Review Article Systematic Review More

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Effect of Psilocybin and Ketamine on Brain Neurotransmitters, Glutamate Receptors, DNA and Rat Behavior.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.3390/ijms23126713 PubMed 35743159

International journal of molecular sciences 2022-06-16 Wojtas A, Bysiek A, Wawrzczak-Bargiela A, Szych Z, Majcher-Maślanka I, Herian M

PubMed Published psilocybin Mechanism of Action Receptor Pharmacology Animal Study Animal Study More

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Interaction Profiles of Central Nervous System Active Drugs at Human Organic Cation Transporters 1-3 and Human Plasma Membrane Monoamine Transporter.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.3390/ijms222312995 PubMed 34884800

International journal of molecular sciences 2021-11-30 Angenoorth TJF, Stankovic S, Niello M, Holy M, Brandt SD, Sitte HH

PubMed Published psilocybin Addiction Receptor Pharmacology In Vitro Study In Vitro Study More

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Many Drugs of Abuse May Be Acutely Transformed to Dopamine, Norepinephrine and Epinephrine In Vivo.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.3390/ijms221910706 PubMed 34639047

International journal of molecular sciences 2021-10-02 Fitzgerald PJ

PubMed Published psilocybin Addiction Neuroplasticity Mechanism of Action Other More

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Chemistry and Toxicology of Major Bioactive Substances in Mushrooms.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.3390/ijms22042218 PubMed 33672330

International journal of molecular sciences 2021-02-23 Patocka J, Wu R, Nepovimova E, Valis M, Wu W, Kuca K

PubMed Published psilocybin psilocin Mechanism of Action Review Article Toxicity Review Article More

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A Single Dose of Psilocybin Increases Synaptic Density and Decreases 5-HT Receptor Density in the Pig Brain.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.3390/ijms22020835 PubMed 33467676

International journal of molecular sciences 2021-01-15 Raval NR, Johansen A, Donovan LL, Ros NF, Ozenne B, Hansen HD

PubMed Published psilocybin Depression Neuroplasticity Receptor Pharmacology Other More

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Total Recall: Lateral Habenula and Psychedelics in the Study of Depression and Comorbid Brain Disorders.

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Details DOI 10.3390/ijms21186525 PubMed 32906643

International journal of molecular sciences 2020-09-07 Vitkauskas M, Mathuru AS

PubMed Published psilocybin Depression Brain Imaging Aging Clinical Trial More