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Psilocybin and psilocin research index

Find psilocybin and psilocin papers, preprints, trials, and citations with clear source context.

Searches titles, authors, journals, identifiers, indexed metadata, and derived research topics. Use Filters to narrow by source, status, substance, study type, or date.

Database 4,967 indexed records Auto-updated on Aug 20, 2026 01:29 UTC

Executed search Topic: Safety 1,208 matching records are displayed.

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Database

4,748 Psilocybin Records 673 Psilocin Records 1,461 Journals 66 Research Topics

Published 4,226 Peer-reviewed / formal records Preprints 437 Marked as not peer reviewed Clinical trials 301 ClinicalTrials.gov records R toolkit visNetwork Bibliometrics, live SQLite analysis, HTML graph, and PDF export

Top journals 1,461 indexed journals

Journal	Records
Journal of psychopharmacology (Oxford, England)	148
Journal of psychoactive drugs	97
Frontiers in psychiatry	90
Psychopharmacology	85
Neuroscience Applied	57
Journal of Psychedelic Studies	48
Psychedelic medicine (New Rochelle, N.Y.)	39
Scientific reports	37
Biological Psychiatry	32
Journal of affective disorders	32

Research topics 66 topic filters

Depression 1,738 Receptor Pharmacology 1,282 Safety 1,208 Review Article 1,075 Mechanism of Action 1,072 Clinical Trial 978 Anxiety 884 Addiction 825 Pharmacology 752 General 538 Animal Study 525 Aging 524 Observational Study 516 Brain Imaging 482 Treatment-Resistant Depression 417 Emotional Processing 409 PTSD 401 Neuroplasticity 399

Source coverage 8 active sources

Source	Count	Share	Status
PubMed	2,566	51.7%	Active
OpenAlex	1,156	23.3%	Active
Crossref	407	8.2%	Active
ClinicalTrials.gov	301	6.1%	Active
Europe PMC	188	3.8%	Active
PsyArXiv	186	3.7%	Active
bioRxiv	124	2.5%	Active

Publication timeline 3,864 dated records

3,864 records since 2020

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Substances Psilocybin 4748 Psilocin 673

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Executed search Topic: Safety 1,208 matching records are displayed.

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1,208 matching records for Topic: Safety.

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Assessing The Readiness of Psychiatrists in Louisiana to Incorporate Psilocybin into Clinical Practice-Lessons Learned from a State Underrepresented in Clinical Psychedelic Research.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1177/28314425251381806 PubMed 42539773

Psychedelic medicine (New Rochelle, N.Y.) 2026-09-01 Husein A, Traylor M, Vest MF, Wood BJ, Brogan M, Thomas A

PubMed Published psilocybin Addiction Observational Study Safety Observational Study More

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Group Retreat Psilocybin Therapy for People with Metastatic Cancer with Anxiety and Depression: A Rite of Passage Facilitation Model for a Phase 1/2 Study.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1177/28314425251404460 PubMed 42539893

Psychedelic medicine (New Rochelle, N.Y.) 2026-09-01 Back AL, McGregor BA, Billingsley L, Blom D, Callan G, Myers S

PubMed Published psilocybin Depression Anxiety Emotional Processing Clinical Trial More

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Balancing safety and access in Oregon’s psilocybin services

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1016/j.drugpo.2026.105384 PubMed 42288041

International Journal of Drug Policy 2026-09-01 Cheung Katherine, Propes Caleigh, Yaden David B.

Crossref Published psilocybin Safety Other More

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Psilocybin in the Treatment of Methamphetamine Use Disorder

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ClinicalTrials.gov 2026-08-19 Peter Hendricks

New this week ClinicalTrials.gov CLINICAL TRIAL psilocybin Safety Clinical Trial More

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Level of Preparedness to Use Psilocybin Among Individuals Seeking Psychedelic Risk Reduction: A retrospective study of a pilot psychiatric consultation service

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.64898/2026.08.17.26360633

medRxiv 2026-08-19 Harrison, H. V.; Gaillard, M.; Cook, R. R.; Sarparast, A.; Levander, X. A.

New this week medRxiv PREPRINT (not peer reviewed) psilocybin Review Article Safety Adverse Events Review Article More

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The subtle science: a systematic review of psilocybin magic mushroom and truffle microdosing

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.3389/fpsyt.2026.1866881

Frontiers in Psychiatry 2026-08-19 Page Jeni, Moore Alexandra, Hawkins Bridget E., Lyons Elizabeth J., Lorenzo Elizabeth

New this week Crossref Published psilocybin Chronic Pain Microdosing Wellbeing Randomized Controlled Trial More

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Safety and Mental Health Outcomes of Oregon State-Regulated Psilocybin Services

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1001/jamanetworkopen.2026.30608

JAMA Network Open 2026-08-19 Korthuis P. Todd, Cook Ryan R., Gregoire Devin, Stauffer Christopher S., Luoma Jason B., Pertl Kellie

New this week Crossref Published psilocybin Depression Anxiety PTSD Observational Study More

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Sex Differences in Acute Responses to Psychedelics: Evidence for Greater Subjective Intensity and Impairment in Female Participants

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.64898/2026.07.08.737179

bioRxiv 2026-08-19 Mason, N. L.; Haijen-Bongers, E. C.; Kuypers, K. P. C.; Frick, A.; Toennes, S. W.; Mallaroni

New this week bioRxiv PREPRINT (not peer reviewed) psilocybin Pharmacology Mechanism of Action Healthy Volunteers Clinical Trial More

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The Abuse Liability of Classic Psychedelics: A Methodological Critique and Assessment of the Quality of Evidence of Recent Studies

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1007/s40429-026-00774-8

Current Addiction Reports 2026-08-18 Michael J. Broman, Jhuma N. Acharya, Kaltum Ahmed, Stacey B. Armstrong, Alan K. Davis

New this week OpenAlex Published psilocybin Clinical Trial Review Article Safety Clinical Trial More

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A Phase 2b/3, Multicentre, Randomised, Double-blind, Controlled Trial, With an Open Label Extension, to Investigate the Efficacy, Safety, and Tolerability of COMP360 in Participants With Post-traumatic Stress Disorder

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ClinicalTrials.gov 2026-08-18 COMPASS Pathways

New this week ClinicalTrials.gov CLINICAL TRIAL psilocybin PTSD Clinical Trial Safety Clinical Trial More

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Assessing Canadian Policy Readiness for Psychedelic-Assisted Therapy in Cancer Care

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.5281/zenodo.21983116

Unknown journal 2026-08-17 Christopher P. Albertyn, Ron Shore, Linda E. Carlson, Erika Dyck, David Clements

New this week OpenAlex Published psilocybin Depression Anxiety Mechanism of Action Clinical Trial More

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Psilocybin-assisted psychotherapy for substance use disorders as a complex intervention: A systematic review of efficacy, mechanisms and psychotherapeutic frameworks

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1177/02698811261473436 PubMed 42609034

Journal of Psychopharmacology 2026-08-17 Strika-Bruneau Lana, Elhssaini Chérine, Fauvel Baptiste, Kervadec Ewen, Bezo Aurore, Amirouche Ammar

New this week Crossref Published psilocybin Addiction Mechanism of Action Wellbeing Systematic Review More

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An Examination of Psilocybin Effects on Biomarkers of Longevity, Healthy Aging, and Purpose in Life

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ClinicalTrials.gov 2026-08-17 Charles Raison

New this week ClinicalTrials.gov CLINICAL TRIAL psilocybin psilocin Neuroplasticity Mechanism of Action Biomarkers Clinical Trial More

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Subacute and long-term changes in cognitive functioning after administration of classic psychedelics, MDMA and ketamine: A systematic review of clinical and preclinical evidence.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1016/j.neubiorev.2026.106911 PubMed 42600962

Neuroscience and biobehavioral reviews 2026-08-14 Kelly C, Cooley BJ, Zeng L, Hurzeler T, Manning V, McNally GP

New this week Europe PMC Published psilocybin Neuroplasticity Systematic Review Review Article Systematic Review More

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The Therapeutic Potential of Psilocybin in Anorexia Nervosa in Young Adults

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ClinicalTrials.gov 2026-08-14 Region Skane

New this week ClinicalTrials.gov CLINICAL TRIAL psilocybin Anxiety Eating Disorders Neuroplasticity Randomized Controlled Trial More

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Safety for Home Administration of Microdose Psilocybin Use

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ClinicalTrials.gov 2026-08-14 Johns Hopkins University

New this week ClinicalTrials.gov CLINICAL TRIAL psilocybin Microdosing Healthy Volunteers Safety Clinical Trial More

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A Multi-site Randomized Controlled Trial of Psilocybin for Treatment-Resistant Depression (TRD) in Veterans

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ClinicalTrials.gov 2026-08-14 VA Office of Research and Development

New this week ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression PTSD Randomized Controlled Trial Randomized Controlled Trial More

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Efficacy and Safety of Psychedelic Microdosing on Psychological Outcomes in Healthy Adults: A Systematic Review and Meta-analysis.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1007/s40263-026-01325-5 PubMed 42593636

CNS drugs 2026-08-13 Meshkat S, Leung M, Lin Q, Wijendran D, Reichelt AC, Zhang Y

New this week Europe PMC Published psilocybin Depression Anxiety Brain Imaging Randomized Controlled Trial More

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Processing Intergenerational Trauma With Psilocybin-Assisted Therapy

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ClinicalTrials.gov 2026-08-13 Rachel Yehuda

New this week ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Anxiety Biomarkers Other More

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PsiloStudy: A Phase 2 Single-site, Double-blind, Placebo-controlled, Randomized Clinical Trial With an Open-label Extension Phase to Examine the Safety, Subjective Experiences, Acute Effects, and Suitability of Psilocybin Combined With Psychological Support (Psi-PS) for Military Veterans and First Responders With Co-occurring Alcohol Use Disorder (AUD) and Posttraumatic Stress Disorder (PTSD)

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ClinicalTrials.gov 2026-08-13 Nathan Brashares Sackett

New this week ClinicalTrials.gov CLINICAL TRIAL psilocybin PTSD Addiction Clinical Trial Clinical Trial More