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Psilocybin and psilocin research index

Find psilocybin and psilocin papers, preprints, trials, and citations with clear source context.

Searches titles, authors, journals, identifiers, indexed metadata, and derived research topics. Use Filters to narrow by source, status, substance, study type, or date.

Database 4,967 indexed records Auto-updated on Aug 20, 2026 01:29 UTC

Executed search Topic: Chronic Pain 291 matching records are displayed.

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Database

4,748 Psilocybin Records 673 Psilocin Records 1,461 Journals 66 Research Topics

Published 4,226 Peer-reviewed / formal records Preprints 437 Marked as not peer reviewed Clinical trials 301 ClinicalTrials.gov records R toolkit visNetwork Bibliometrics, live SQLite analysis, HTML graph, and PDF export

Top journals 1,461 indexed journals

Journal	Records
Journal of psychopharmacology (Oxford, England)	148
Journal of psychoactive drugs	97
Frontiers in psychiatry	90
Psychopharmacology	85
Neuroscience Applied	57
Journal of Psychedelic Studies	48
Psychedelic medicine (New Rochelle, N.Y.)	39
Scientific reports	37
Biological Psychiatry	32
Journal of affective disorders	32

Research topics 66 topic filters

Depression 1,738 Receptor Pharmacology 1,282 Safety 1,208 Review Article 1,075 Mechanism of Action 1,072 Clinical Trial 978 Anxiety 884 Addiction 825 Pharmacology 752 General 538 Animal Study 525 Aging 524 Observational Study 516 Brain Imaging 482 Treatment-Resistant Depression 417 Emotional Processing 409 PTSD 401 Neuroplasticity 399

Source coverage 8 active sources

Source	Count	Share	Status
PubMed	2,566	51.7%	Active
OpenAlex	1,156	23.3%	Active
Crossref	407	8.2%	Active
ClinicalTrials.gov	301	6.1%	Active
Europe PMC	188	3.8%	Active
PsyArXiv	186	3.7%	Active
bioRxiv	124	2.5%	Active

Publication timeline 3,864 dated records

3,864 records since 2020

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Substances Psilocybin 4748 Psilocin 673

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Executed search Topic: Chronic Pain 291 matching records are displayed.

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291 matching records for Topic: Chronic Pain.

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Effects of psilocybin and sleep quality on brain water diffusivity and microstructure in healthy individuals and chronic cluster headache patients

No abstract availability was recorded for this entry.

Details DOI 10.1016/j.nsa.2024.105131

Neuroscience Applied 2024-01-01 Kristoffer Brendstrup-Brix, Patrick M. Fisher, Dea Siggaard Stenbæk, Anja Sofie Petersen, Stéphane Armand, Drummond E-Wen McCulloch

OpenAlex Published psilocybin Chronic Pain Headache / Migraine Other More

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Psychedelics: The New Kid on the Block

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.4103/aip.aip_195_23

Annals of Indian Psychiatry 2024-01-01 Prosenjit Ghosh, Avinash Desousa

OpenAlex Published psilocybin Depression Anxiety Addiction Randomized Controlled Trial More

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Potential analgesic effects of psychedelics on select chronic pain conditions: A survey study.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1002/ejp.2171 PubMed 37599279

European journal of pain (London, England) 2024-01-01 Cavarra M, Mason NL, Kuypers KPC, Bonnelle V, Smith WJ, Feilding A

PubMed Published psilocybin Chronic Pain Headache / Migraine Microdosing Observational Study More

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Potential Benefits of Psilocybin for Lupus Pain: A Case Report.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.2174/1573397119666230904150750 PubMed 37670693

Current rheumatology reviews 2024-01-01 Gonzales SAB, Alexopoulos C, Arkfeld DG

PubMed Published psilocybin Chronic Pain Mechanism of Action Receptor Pharmacology Case Report More

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Scoping Review: The Role of Psychedelics in the Management of Chronic Pain.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.2147/jpr.s439348 PubMed 38496341

Journal of pain research 2024-01-01 Robinson CL, Fonseca ACG, Diejomaoh EM, D'Souza RS, Schatman ME, Orhurhu V

PubMed Published psilocybin Chronic Pain Headache / Migraine Receptor Pharmacology Meta-Analysis More

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Study protocol for "Psilocybin in patients with fibromyalgia: brain biomarkers of action".

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.3389/fpsyt.2024.1320780 PubMed 38983371

Frontiers in psychiatry 2024-01-01 Bornemann J, Close JB, Ahmad K, Barba T, Godfrey K, Macdonald L

PubMed Published psilocybin Chronic Pain Neuroplasticity Brain Imaging Randomized Controlled Trial More

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Low-dose psilocybin in short-lasting unilateral neuralgiform headache attacks: results from an open-label phase Ib ascending dose study.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1111/head.14837 PubMed 39301810

Headache 2024-01-01 Rucker J, Butler M, Hambleton S, Bird C, Seynaeve M, Cheema S

PubMed Published psilocybin Chronic Pain Headache / Migraine Receptor Pharmacology Clinical Trial More

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Prospective Preference Assessment for the Psilocybin for Enhanced Analgesia in Chronic nEuropathic PAIN (PEACE-PAIN) Trial.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1080/24740527.2024.2406285 PubMed 39529994

Canadian journal of pain = Revue canadienne de la douleur 2024-01-01 Lee J, Philip K, Wijeysundera DN, Clarke H, Pritlove C, Katz J

PubMed Published psilocybin Chronic Pain Aging Randomized Controlled Trial Randomized Controlled Trial More

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Intravenous psilocybin attenuates mechanical hypersensitivity in a rat model of chronic pain.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1016/j.cub.2023.10.016 PubMed 38113836

Current biology: CB 2023-12-18 Kolbman N, Liu T, Guzzo P, Gilligan J, Mashour GA, Vanini G

PubMed Published psilocybin Depression Addiction Chronic Pain Animal Study More

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Psychedelic Integration: Psychotherapy for non-ordinary states of consciousness

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1556/2054.2023.00306

Journal of Psychedelic Studies 2023-11-16 Danelle Jones

OpenAlex Published psilocybin Depression Anxiety PTSD Clinical Trial More

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LSD and psilocybin for chronic nociplastic pain: A narrative review of the literature supporting the use of classic psychedelic agents in chronic pain.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.7196/samj.2023.v113i11.814 PubMed 38525640

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 2023-11-06 Van Der Walt J, Parker R

PubMed Published psilocybin Depression Chronic Pain Mechanism of Action Review Article More

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Acute effects of psilocybin on the dynamics of gaze fixations during visual aesthetic perception

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1101/2023.10.27.564413

bioRxiv 2023-11-01 Muller S, Cavanna F, de la Fuente L, Bruno N, D’Amelio TA, Pallavicini C

bioRxiv PREPRINT (not peer reviewed) psilocybin Chronic Pain Consciousness Emotional Processing Other More

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Shame, guilt and psychedelic experience: Results from a prospective, longitudinal survey of real-world psilocybin use

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.31234/osf.io/hm6jn

PsyArXiv 2023-10-14 Mathai DS, Roberts DE, Nayak SM, Sepeda ND, Lehrner A, Johnson M

PsyArXiv PREPRINT (not peer reviewed) psilocybin Chronic Pain Wellbeing Emotional Processing Observational Study More

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Shame, guilt and psychedelic experience: Results from a prospective, longitudinal survey of real-world psilocybin use

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.31234/osf.io/hm6jn_v1

PsyArXiv 2023-10-14 Mathai DS, Roberts DE, Nayak SM, Sepeda ND, Lehrner A, Johnson M

PsyArXiv PREPRINT (not peer reviewed) psilocybin Chronic Pain Wellbeing Emotional Processing Observational Study More

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Shame, guilt and psychedelic experience: Results from a prospective, longitudinal survey of real-world psilocybin use

Abstract available at the source but not redistributed here. Read at source.

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PsyArXiv 2023-10-14 David S Mathai, Daniel E Roberts, Sandeep M Nayak, Nathan D Sepeda, Amy Lehrner, Matthew Johnson

PsyArXiv PREPRINT (not peer reviewed) psilocybin Chronic Pain Pharmacology Wellbeing Observational Study More

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Psychedelics and Psychotherapy: Is the Whole Greater than the Sum of its Parts?

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1002/cpt.3050 PubMed 37795632

Clinical Pharmacology & Therapeutics 2023-10-05 Robert H. Dworkin, Michael McDermott, Sandeep M. Nayak, Eric C. Strain

OpenAlex Published psilocybin Depression Anxiety Addiction Clinical Trial More

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Use of Psychedelics for Pain: A Scoping Review.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1097/aln.0000000000004673 PubMed 37698433

Anesthesiology 2023-10-01 Goel A, Rai Y, Sivadas S, Diep C, Clarke H, Shanthanna H

PubMed Published psilocybin Addiction Chronic Pain Headache / Migraine Clinical Trial More

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Psychedelics: Threshold of a Therapeutic Revolution.

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Details DOI 10.1016/j.neuropharm.2023.109610 PubMed 37247807

Neuropharmacology 2023-09-15 Heal DJ, Smith SL, Belouin SJ, Henningfield JE

PubMed Published psilocybin Depression Anxiety PTSD Clinical Trial More

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The Potential of Psychedelics for the Treatment of Episodic Migraine.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1007/s11916-023-01145-y PubMed 37540398

Current pain and headache reports 2023-09-01 Schindler EAD

PubMed Published psilocybin Chronic Pain Headache / Migraine Clinical Trial Clinical Trial More

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Intravenous psilocybin administration attenuates mechanical hypersensitivity in a rat model of chronic pain

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1101/2023.08.26.554802

bioRxiv 2023-08-28 Kolbman N, Liu T, Guzzo P, Gilligan JP, Mashour GA, Vanini G

bioRxiv PREPRINT (not peer reviewed) psilocybin Chronic Pain Animal Study Animal Study More