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Psilocybin and psilocin research index

Find psilocybin and psilocin papers, preprints, trials, and citations with clear source context.

Searches titles, authors, journals, identifiers, indexed metadata, and derived research topics. Use Filters to narrow by source, status, substance, study type, or date.

Database 4,967 indexed records Auto-updated on Aug 20, 2026 01:29 UTC

Executed search Evidence: clinical trial 301 matching records are displayed.

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Database

4,748 Psilocybin Records 673 Psilocin Records 1,461 Journals 66 Research Topics

Published 4,226 Peer-reviewed / formal records Preprints 437 Marked as not peer reviewed Clinical trials 301 ClinicalTrials.gov records R toolkit visNetwork Bibliometrics, live SQLite analysis, HTML graph, and PDF export

Top journals 1,461 indexed journals

Journal	Records
Journal of psychopharmacology (Oxford, England)	148
Journal of psychoactive drugs	97
Frontiers in psychiatry	90
Psychopharmacology	85
Neuroscience Applied	57
Journal of Psychedelic Studies	48
Psychedelic medicine (New Rochelle, N.Y.)	39
Scientific reports	37
Biological Psychiatry	32
Journal of affective disorders	32

Research topics 66 topic filters

Depression 1,738 Receptor Pharmacology 1,282 Safety 1,208 Review Article 1,075 Mechanism of Action 1,072 Clinical Trial 978 Anxiety 884 Addiction 825 Pharmacology 752 General 538 Animal Study 525 Aging 524 Observational Study 516 Brain Imaging 482 Treatment-Resistant Depression 417 Emotional Processing 409 PTSD 401 Neuroplasticity 399

Source coverage 8 active sources

Source	Count	Share	Status
PubMed	2,566	51.7%	Active
OpenAlex	1,156	23.3%	Active
Crossref	407	8.2%	Active
ClinicalTrials.gov	301	6.1%	Active
Europe PMC	188	3.8%	Active
PsyArXiv	186	3.7%	Active
bioRxiv	124	2.5%	Active

Publication timeline 3,864 dated records

3,864 records since 2020

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Substances Psilocybin 4748 Psilocin 673

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Executed search Evidence: clinical trial 301 matching records are displayed.

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301 matching records for Evidence: clinical trial.

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A Phase 2a, Placebo-Controlled Randomized, Double-Blind Trial to Evaluate the Safety, Tolerability, and Preliminary Efficacy of Psilocybin Oral Solution in Adults With Generalized Anxiety Disorder

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ClinicalTrials.gov 2026-08-12 Claudio N Soares

New this month ClinicalTrials.gov CLINICAL TRIAL psilocybin Anxiety Brain Imaging Clinical Trial Clinical Trial More

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Psilocybin Recovery Intervention for Stopping Methamphetamine Use

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ClinicalTrials.gov 2026-08-11 Nicky Mehtani, MD, MPH

New this month ClinicalTrials.gov CLINICAL TRIAL psilocybin Clinical Trial Clinical Trial More

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Effects of Psilocybin in Patients With Amyotrophic Lateral Sclerosis

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ClinicalTrials.gov 2026-08-11 Johns Hopkins University

New this month ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Other More

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An Investigation of Strategies to Understand and Optimize the Antidepressant Effects of Psilocybin (The OPTIMIZE Study)

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ClinicalTrials.gov 2026-08-10 Charles Raison

New this month ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Anxiety Aging Clinical Trial More

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A Phase III, Multicentre, Randomised, Double-blind, Controlled Study to Investigate the Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in Participants With Treatment-resistant Depression

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ClinicalTrials.gov 2026-08-10 COMPASS Pathways

New this month ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Clinical Trial Treatment-Resistant Depression Clinical Trial More

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Safety, Tolerability, Outcomes of Psilocybin for Depression (STOP Depression) in Veterans With Spinal Cord Injury

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ClinicalTrials.gov 2026-08-10 James J. Peters Veterans Affairs Medical Center

New this month ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Chronic Pain Mechanism of Action Other More

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A Phase III, Multicentre, Randomised, Double-blind, Placebo-controlled Study to Investigate the Efficacy, Safety, and Tolerability of COMP360 in Participants With Treatment-resistant Depression

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ClinicalTrials.gov 2026-08-10 COMPASS Pathways

New this month ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Clinical Trial Treatment-Resistant Depression Clinical Trial More

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A Multicenter Phase 1 Safety and Tolerability Trial of Psilocybin in Healthy Older Adults

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ClinicalTrials.gov 2026-08-10 University of Colorado, Denver

New this month ClinicalTrials.gov CLINICAL TRIAL psilocybin Pharmacology Aging Wellbeing Clinical Trial More

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Neurobiological Effects of Psilocybin in Treatment Resistant Bipolar Depression: An Emotional-Processing fMRI Pilot Study

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ClinicalTrials.gov 2026-08-10 University Health Network, Toronto

New this month ClinicalTrials.gov CLINICAL TRIAL psilocybin psilocin Depression Brain Imaging Mechanism of Action Randomized Controlled Trial More

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Neuroplasticity Enhancement From Cognitive Training Reinforced by Psilocybin (NECTAR) in Aging and Alzheimer's Disease

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ClinicalTrials.gov 2026-08-07 National Institute on Aging (NIA)

New this month ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Anxiety PTSD Clinical Trial More

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The Efficacy of Psilocybin Therapy for Depression in Parkinson's Disease

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ClinicalTrials.gov 2026-08-07 Joshua Woolley, MD, PhD

New this month ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Brain Imaging Biomarkers Randomized Controlled Trial More

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Open Label Psilocybin Brain Stimulation and Imaging Pilot Study

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ClinicalTrials.gov 2026-08-07 Johns Hopkins University

New this month ClinicalTrials.gov CLINICAL TRIAL psilocybin Brain Imaging Aging Healthy Volunteers Other More

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Single Dose Psilocybin for a Post-surgical Trauma Inpatient Population for Pain, Mood, and Opioid Use Disorder

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ClinicalTrials.gov 2026-08-06 Trent Emerick

New this month ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Anxiety Addiction Clinical Trial More

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Psilocybin for Treatment-Resistant Depression in Autism: a Pilot Trial With Pre-Post Brain and Cognitive Measurement to Understand Mechanism

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ClinicalTrials.gov 2026-08-06 Centre for Addiction and Mental Health

New this month ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Consciousness Clinical Trial Clinical Trial More

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An Exploratory Study of Feasibility, Efficacy, and Mechanisms of Mindfulness-Assisted Psychedelic Therapy

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ClinicalTrials.gov 2026-08-06 University of Southern California

New this month ClinicalTrials.gov CLINICAL TRIAL psilocybin Brain Imaging Mechanism of Action Biomarkers Clinical Trial More

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Feasibility Phase 2 Study of Psilocybin-Assisted Therapy for Opioid-Refractory Pain in Patients With Advanced Cancer

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ClinicalTrials.gov 2026-08-05 Yvan Beaussant, MD, MSci

New this month ClinicalTrials.gov CLINICAL TRIAL psilocybin Addiction End-of-Life Distress Chronic Pain Clinical Trial More

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Precision Phenotyping of Behavioral Risk and Response to Electromagnetic and Psychedelic Therapies

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ClinicalTrials.gov 2026-08-04 University of New Mexico

New this month ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression PTSD Brain Imaging Observational Study More

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Psilocybin as a Treatment for Chronic Pain in Smokers

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ClinicalTrials.gov 2026-08-03 Yale University

New this month ClinicalTrials.gov CLINICAL TRIAL psilocybin Addiction Chronic Pain Headache / Migraine Clinical Trial More

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Psilocybin for Chronic Pelvic Pain (CPP) in Women: A Pilot Feasibility Study

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ClinicalTrials.gov 2026-08-03 Oregon Health and Science University

New this month ClinicalTrials.gov CLINICAL TRIAL psilocybin Chronic Pain Safety Adverse Events Other More

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A Phase 2a Study of Group Retreat Psilocybin Therapy for Cancer-Related Anxiety and Depression

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ClinicalTrials.gov 2026-07-31 University of Washington

New this month ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Anxiety Clinical Trial Clinical Trial More