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Psilocybin and psilocin research index

Find psilocybin and psilocin papers, preprints, trials, and citations with clear source context.

Searches titles, authors, journals, identifiers, indexed metadata, and derived research topics. Use Filters to narrow by source, status, substance, study type, or date.

Database 4,959 indexed records Auto-updated on Aug 17, 2026 01:21 UTC

Executed search Sources: PubMed 2,567 matching records are displayed.

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Database

4,740 Psilocybin Records 673 Psilocin Records 1,461 Journals 66 Research Topics

Published 4,221 Peer-reviewed / formal records Preprints 435 Marked as not peer reviewed Clinical trials 300 ClinicalTrials.gov records R toolkit visNetwork Bibliometrics, live SQLite analysis, HTML graph, and PDF export

Top journals 1,461 indexed journals

Journal	Records
Journal of psychopharmacology (Oxford, England)	147
Journal of psychoactive drugs	97
Frontiers in psychiatry	90
Psychopharmacology	85
Neuroscience Applied	57
Journal of Psychedelic Studies	48
Psychedelic medicine (New Rochelle, N.Y.)	39
Scientific reports	37
bioRxiv : the preprint server for biology	33
Biological Psychiatry	32

Research topics 66 topic filters

Depression 1,736 Receptor Pharmacology 1,282 Safety 1,201 Mechanism of Action 1,070 Review Article 1,070 Clinical Trial 975 Anxiety 882 Addiction 823 Pharmacology 753 General 537 Aging 524 Animal Study 524 Observational Study 515 Brain Imaging 481 Treatment-Resistant Depression 417 Emotional Processing 409 PTSD 400 Neuroplasticity 399

Source coverage 8 active sources

Source	Count	Share	Status
PubMed	2,567	51.8%	Active
OpenAlex	1,154	23.3%	Active
Crossref	404	8.1%	Active
ClinicalTrials.gov	300	6%	Active
Europe PMC	187	3.8%	Active
PsyArXiv	187	3.8%	Active
bioRxiv	122	2.5%	Active

Publication timeline 3,856 dated records

3,856 records since 2020

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Substances Psilocybin 4740 Psilocin 673

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Executed search Sources: PubMed 2,567 matching records are displayed.

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2,567 matching records for Sources: PubMed.

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Sample composition and HIV prevention indicator differences using physical vs virtual venue recruitment of men who have sex with men in San Francisco.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1093/aje/kwae443 PubMed 39673252

American journal of epidemiology 2025-09-03 Chiu I, Tate M, Trujillo D, Suprasert B, Marr A, Arayasirikul S

PubMed Published psilocybin Safety Other More

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Therapeutic Use of Psilocybin in Depression: a Systematic Review of Clinical Evidence.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1017/neu.2025.10039 PubMed 40899152

Acta neuropsychiatrica 2025-09-03 Andrade FRT, Buchborn T, Thalheimer G, Meinhardt MW, Joca S, de Almeida RMM

PubMed Published psilocybin Depression Anxiety Headache / Migraine Randomized Controlled Trial More

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Integrating Holistic Communication into Psychedelic-Assisted Therapies in Hospice and Palliative Care: An Approach Based on Peplau's Theory.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1177/08980101251374371 PubMed 40900021

Journal of holistic nursing: official journal of the American Holistic Nurses' Association 2025-09-03 Mesquita Garcia AC, Teixeira F, Maia LO

PubMed Published psilocybin Anxiety End-of-Life Distress Emotional Processing Other More

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Active Constituents of Psilocybin Mushroom Edibles.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1001/jamanetworkopen.2025.31345 PubMed 40932719

JAMA network open 2025-09-02 van Breemen RB, Simchuk D, Fritzsche B, Huson D, Kuzdzal SA, Ferguson J

PubMed Published psilocybin General Other More

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"Wood-lover paralysis": Describing a toxidrome with symptoms of weakness caused by some lignicolous "wood-loving" Psilocybe mushrooms.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1016/j.toxicon.2025.108450 PubMed 40490153

Toxicon: official journal of the International Society on Toxinology 2025-09-01 Beck SA, Barlow C, Engel L, Barratt MJ

PubMed Published psilocybin Observational Study Observational Study More

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Separate or inseparable? Serotonin and dopamine system interactions may underlie the therapeutic potential of psilocybin for anorexia nervosa.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1016/j.physbeh.2025.114957 PubMed 40403997

Physiology & behavior 2025-09-01 McCoy K, Reed F, Conn K, Foldi CJ

PubMed Published psilocybin Eating Disorders End-of-Life Distress Neuroplasticity Other More

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A critical evaluation of psilocybin-assisted therapy protocol components from clinical trial patients, facilitators, and caregivers.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1037/pst0000551 PubMed 39804360

Psychotherapy (Chicago, Ill.) 2025-09-01 Palitsky R, Maples-Keller JL, Peacock C, Dunlop BW, Mletzko T, Grant GH

PubMed Published psilocybin Chronic Pain Spirituality Clinical Trial Clinical Trial More

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Quantitative natural language processing markers of psychoactive drug effects: A pre-registered systematic review.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1177/02698811251319455 PubMed 39956789

Journal of psychopharmacology (Oxford, England) 2025-09-01 Ahuja S, Zaher F, Palaniyappan L

PubMed Published psilocybin Addiction Pharmacology Biomarkers Meta-Analysis More

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Lifetime classic psychedelic use and headaches: A cross-sectional study.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1177/02698811251324372 PubMed 40071875

Journal of psychopharmacology (Oxford, England) 2025-09-01 Bjurenfalk Z, Cosmo A, Simonsson O, Ran C

PubMed Published psilocybin Headache / Migraine Observational Study Observational Study More

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Psilocybin biosynthesis enhancement through gene source optimization.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1016/j.ymben.2025.04.003 PubMed 40250599

Metabolic engineering 2025-09-01 Keller MR, McKinney MG, Sen AK, Guagliardo FG, Hellwarth EB, Islam KN

PubMed Published psilocybin Depression Anxiety Pharmacology Clinical Trial More

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Set and setting of psychedelics for therapeutic use in psychiatry: A systematic review.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1177/02698811251338214 PubMed 40353492

Journal of psychopharmacology (Oxford, England) 2025-09-01 Estric C, Duron T, Kabani S, Lopez-Castroman J

PubMed Published psilocybin Clinical Trial Systematic Review Review Article Systematic Review More

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Effects of serotonergic psychedelics on synaptogenesis and immediate early genes expression - comparison with ketamine, fluoxetine and lithium.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1177/02698811251338232 PubMed 40437853

Journal of psychopharmacology (Oxford, England) 2025-09-01 Vella Y, Syrová K, Petrušková A, Koutrouli I, Kútna V, Pala J

PubMed Published psilocin Neuroplasticity Mechanism of Action Biomarkers Animal Study More

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Adverse reactions among psychedelic users: Norwegian validation of the Challenging Experience Questionnaire.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1016/j.jpsychires.2025.05.062 PubMed 40466556

Journal of psychiatric research 2025-09-01 Andersen KAA, Holmøy B, Kvam TM, Johnson MW

PubMed Published psilocybin Observational Study Observational Study More

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Self-inflicted transorbital intracranial foreign body following ingestion of hallucinogenic psilocybin mushrooms.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1016/j.ajoc.2025.102359 PubMed 40535325

American journal of ophthalmology case reports 2025-09-01 Blanton AM, Parikh P, Zhou S, Mohamed M, Ufret-Vincenty RL, Mancini R

PubMed Published psilocybin Depression Anxiety Case Report Case Report More

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Examining mystical experiences as a predictor of psilocybin-assisted psychotherapy for treatment-resistant depression.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1177/02698811251346697 PubMed 40590216

Journal of psychopharmacology (Oxford, England) 2025-09-01 Brudner RM, Kaczmarek E, Blainey MG, Schulz-Quach C, Meshkat S, Doyle Z

PubMed Published psilocybin Depression Mechanism of Action Mystical Experience Other More

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Psychedelics for Alcohol Use Disorder: A Narrative Review with Candidate Mechanisms of Action.

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Details DOI 10.1007/s40263-025-01199-z PubMed 40640527

CNS drugs 2025-09-01 Miller EA, Capone C, Eaton E, Swift RM, Haass-Koffler CL

PubMed Published psilocybin Addiction Neuroplasticity Mechanism of Action Clinical Trial More

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Unequal representation? A cross-sectional analysis of age, sex, race, and ethnicity in clinical trials of classic psychedelics.

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Details DOI 10.1177/02698811251353250 PubMed 40643096

Journal of psychopharmacology (Oxford, England) 2025-09-01 Swieczkowski D, Kwaśny A, Ciurkowska P, Pruc M, Szarpak L, Cubała WJ

PubMed Published psilocybin psilocin Aging Clinical Trial Review Article Clinical Trial More

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A systematic review and narrative summary of the therapeutic potential of classic serotonergic psychedelics for smoking cessation and reduction.

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Details DOI 10.1177/02698811251353251 PubMed 40643107

Journal of psychopharmacology (Oxford, England) 2025-09-01 Glenn DL, Choi SH, Zimmerman RS

PubMed Published psilocybin Addiction Mechanism of Action Receptor Pharmacology Systematic Review More

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Attitudes toward psychedelics and psychedelic-assisted psychotherapy among Australian mental healthcare providers.

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Details DOI 10.1177/00048674251346679 PubMed 40660894

The Australian and New Zealand journal of psychiatry 2025-09-01 Nadeem Z, Parker S, McGovern H, Sebben B, Oestreich LK

PubMed Published psilocybin Depression PTSD Observational Study Observational Study More

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Psilocybin as a psychophysical adaptogen in chronic pain rehabilitation.

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Details DOI 10.1016/j.jpain.2025.105507 PubMed 40701207

The journal of pain 2025-09-01 Cherup NP, Finan PH

PubMed Published psilocybin Depression Anxiety Chronic Pain Other More