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Psilocybin and psilocin research index

Find psilocybin and psilocin papers, preprints, trials, and citations with clear source context.

Searches titles, authors, journals, identifiers, indexed metadata, and derived research topics. Use Filters to narrow by source, status, substance, study type, or date.

Database 4,967 indexed records Auto-updated on Aug 20, 2026 01:29 UTC

Executed search Topic: Spirituality 269 matching records are displayed.

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Database

4,748 Psilocybin Records 673 Psilocin Records 1,461 Journals 66 Research Topics

Published 4,226 Peer-reviewed / formal records Preprints 437 Marked as not peer reviewed Clinical trials 301 ClinicalTrials.gov records R toolkit visNetwork Bibliometrics, live SQLite analysis, HTML graph, and PDF export

Top journals 1,461 indexed journals

Journal	Records
Journal of psychopharmacology (Oxford, England)	148
Journal of psychoactive drugs	97
Frontiers in psychiatry	90
Psychopharmacology	85
Neuroscience Applied	57
Journal of Psychedelic Studies	48
Psychedelic medicine (New Rochelle, N.Y.)	39
Scientific reports	37
Biological Psychiatry	32
Journal of affective disorders	32

Research topics 66 topic filters

Depression 1,738 Receptor Pharmacology 1,282 Safety 1,208 Review Article 1,075 Mechanism of Action 1,072 Clinical Trial 978 Anxiety 884 Addiction 825 Pharmacology 752 General 538 Animal Study 525 Aging 524 Observational Study 516 Brain Imaging 482 Treatment-Resistant Depression 417 Emotional Processing 409 PTSD 401 Neuroplasticity 399

Source coverage 8 active sources

Source	Count	Share	Status
PubMed	2,566	51.7%	Active
OpenAlex	1,156	23.3%	Active
Crossref	407	8.2%	Active
ClinicalTrials.gov	301	6.1%	Active
Europe PMC	188	3.8%	Active
PsyArXiv	186	3.7%	Active
bioRxiv	124	2.5%	Active

Publication timeline 3,864 dated records

3,864 records since 2020

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Substances Psilocybin 4748 Psilocin 673

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Executed search Topic: Spirituality 269 matching records are displayed.

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269 matching records for Topic: Spirituality.

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Open Label, Phase 2 Study for Evaluating the Feasibility, Safety and Efficacy of Psychotherapy Assisted Psilocybin for Treatment of Severe Obsessive Compulsive Disorder (OCD) in Drug and/or Psychotherapy Resistant Patients.

Abstract available at the source but not redistributed here. Read at source.

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ClinicalTrials.gov 2025-11-19 Beersheva Mental Health Center

ClinicalTrials.gov CLINICAL TRIAL psilocybin psilocin Depression Anxiety Addiction Clinical Trial More

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Spiritual dimension and psychedelic experiences: A phenomenological approach

Abstract available at the source but not redistributed here. Read at source.

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PhilArchive 2025-11-15 Vargas Ibarra, Pablo

OpenAlex PREPRINT (not peer reviewed) psilocybin Consciousness Spirituality Mystical Experience Review Article More

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Psychedelic Augmentation of 12-Step Engagement: A Novel, Accessible Approach to Enhance Community-Based Recovery from Substance Use Disorders.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1080/02791072.2025.2583960 PubMed 41214462

Journal of psychoactive drugs 2025-11-10 Mehtani NJ, Mian MN, Agin-Liebes G, Coker AR, Huebner C, Anderson BT

PubMed Published psilocybin Addiction Mechanism of Action Wellbeing Qualitative Study More

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A Tragedy of Errors: The State of Psychedelic Research in the Treatment of Alcohol Use Disorder.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.3390/brainsci15111190 PubMed 41300197

Brain sciences 2025-11-04 Srivastava AB, Gold MS

PubMed Published psilocybin Addiction Brain Imaging Aging Review Article More

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“It Fueled the Fire to Who I Am Now”: Exploring Motivations for Microdosing Psychedelics

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1177/00220426251395178

Journal of Drug Issues 2025-10-31 Blake Beaton

OpenAlex Published psilocybin Depression Anxiety Addiction Other More

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A Wellcome Leap for the Opioid Crisis: Can the 5HT2A Agonist Psilocybin Improve Brain, Behavioral, and Clinical Outcomes in Opioid Use Disorder (OUD)?

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ClinicalTrials.gov 2025-10-29 Anna Rose Childress, Ph.D.

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Addiction OCD Clinical Trial More

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Home-based psilocybin-assisted therapy for a patient with advanced cancer: A case report.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1017/s1478951525100941 PubMed 41127918

Palliative & supportive care 2025-10-23 Farzin H, Koren B, Ferrier H, Sanders JJ, Garel N

PubMed Published psilocybin Depression Anxiety End-of-Life Distress Case Report More

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Understanding psilocybin mushrooms and aiding in setting standards for a burgeoning industry in Jamaica

No abstract availability was recorded for this entry.

Details DOI 10.1016/j.phytol.2025.103139

Phytochemistry Letters 2025-10-01 Rupika Delgoda, Kimberley Foster, Isaac Morrison, Marshall Tyler, William Irvine, Lavonne Wilson

OpenAlex Published psilocybin Spirituality Other More

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Psychedelics Offer Healing and Ecological Remembrance for Marginalized Individuals Failed by U.S. Health Care

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1177/19429347251382234

Ecopsychology 2025-09-29 Nicole Torres

OpenAlex Published psilocybin Emotional Processing Spirituality Qualitative Study More

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Mindset Over Molecule: Comparing Self-Transcendent and Mystical Experiences Across Recreational Psilocybin, MDMA, and Cannabis Use

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.21203/rs.3.rs-7266162/v1

Research Square 2025-09-12 Chwyl C, Spata A, Lucas W, Luoma JB.

Europe PMC PREPRINT (not peer reviewed) psilocybin Mechanism of Action Personality Change Emotional Processing Clinical Trial More

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Integrating Holistic Communication into Psychedelic-Assisted Therapies in Hospice and Palliative Care: An Approach Based on Peplau's Theory.

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Details DOI 10.1177/08980101251374371 PubMed 40900021

Journal of holistic nursing: official journal of the American Holistic Nurses' Association 2025-09-03 Mesquita Garcia AC, Teixeira F, Maia LO

PubMed Published psilocybin Anxiety End-of-Life Distress Emotional Processing Other More

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A critical evaluation of psilocybin-assisted therapy protocol components from clinical trial patients, facilitators, and caregivers.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1037/pst0000551 PubMed 39804360

Psychotherapy (Chicago, Ill.) 2025-09-01 Palitsky R, Maples-Keller JL, Peacock C, Dunlop BW, Mletzko T, Grant GH

PubMed Published psilocybin Chronic Pain Spirituality Clinical Trial Clinical Trial More

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“To Have the Encounter with Our Own Finiteness in that Existential Way”: Descriptions of Existential Experience in Patients with Cancer and Major Depression Participating in Psilocybin-Assisted Group Therapy

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1177/28314425251370303

Psychedelic Medicine 2025-08-25 Elise C. Tarbi, Skye A. Miner, Kabir Nigam, Zachary Sager, Justin J. Sanders, Michael Ljuslin

OpenAlex Published psilocybin Depression Spirituality Clinical Trial Clinical Trial More

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Psychedelic researchers’ own experiences of psychedelic substances, their link to opinions of psychedelics, and reflections on positionality

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Details DOI 10.1007/s00213-025-06871-2 PubMed 40788485

Psychopharmacology 2025-08-10 Jussi Jylkkä, Aila Mustamo

OpenAlex Published psilocybin Wellbeing Spirituality Toxicity Other More

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Psychedelics, Spirituality, and Fundamentalism: A Brain Network Approach to Cognitive Flexibility and Rigidity.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1021/acschemneuro.5c00509 PubMed 40702747

ACS chemical neuroscience 2025-08-06 Yang A, Lv X, Wang H, Wang X

PubMed Published psilocybin Spirituality Mystical Experience Other More

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Interventions to support spirituality among adults with cancer: a scoping review.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1007/s00520-025-09787-x PubMed 40751754

Supportive care in cancer: official journal of the Multinational Association of Supportive Care in Cancer 2025-08-02 Miller M, Meyers M, Krainak K, Lewis SP

PubMed Published psilocybin End-of-Life Distress Wellbeing Spirituality Review Article More

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Explore the effect of psilocybin on depression and anxiety

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.61173/rcg8me57

Arts Culture and Language 2025-07-06 Yutong Song

OpenAlex Published psilocybin Depression Anxiety Addiction Other More

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Beyond prohibition: A public health analysis of naturalistic psychedelic use

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Details DOI 10.1556/2054.2025.00450

Journal of Psychedelic Studies 2025-07-03 Mark Haden, Sarah A. Paschall, Birgitta Woods

OpenAlex Published psilocybin Depression Anxiety PTSD Review Article More

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Mystical States & Psilocybin. From Dissociation Towards Association: A Conversational Model Discussion

No abstract availability was recorded for this entry.

Details DOI 10.66330/100520252

The Therapeutic Conversation 2025-05-31 Toby A. Clark

OpenAlex Published psilocybin Spirituality Mystical Experience Other More

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Role of the Serotonin 2A Receptor in Psilocybin-induced Altered States of Consciousness (PDR-Study)

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ClinicalTrials.gov 2025-05-28 University Hospital, Basel, Switzerland

ClinicalTrials.gov CLINICAL TRIAL psilocybin psilocin Depression Anxiety Addiction Other More