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Psilocybin and psilocin research index

Find psilocybin and psilocin papers, preprints, trials, and citations with clear source context.

Searches titles, authors, journals, identifiers, indexed metadata, and derived research topics. Use Filters to narrow by source, status, substance, study type, or date.

Database 4,961 indexed records Auto-updated on Aug 19, 2026 01:24 UTC

Executed search Sources: PubMed 2,566 matching records are displayed.

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Database

4,742 Psilocybin Records 673 Psilocin Records 1,461 Journals 66 Research Topics

Published 4,223 Peer-reviewed / formal records Preprints 435 Marked as not peer reviewed Clinical trials 300 ClinicalTrials.gov records R toolkit visNetwork Bibliometrics, live SQLite analysis, HTML graph, and PDF export

Top journals 1,461 indexed journals

Journal	Records
Journal of psychopharmacology (Oxford, England)	148
Journal of psychoactive drugs	97
Frontiers in psychiatry	90
Psychopharmacology	85
Neuroscience Applied	57
Journal of Psychedelic Studies	48
Psychedelic medicine (New Rochelle, N.Y.)	39
Scientific reports	37
Biological Psychiatry	32
Journal of affective disorders	32

Research topics 66 topic filters

Depression 1,737 Receptor Pharmacology 1,281 Safety 1,203 Mechanism of Action 1,072 Review Article 1,072 Clinical Trial 977 Anxiety 883 Addiction 824 Pharmacology 752 General 538 Aging 524 Animal Study 524 Observational Study 515 Brain Imaging 481 Treatment-Resistant Depression 417 Emotional Processing 409 PTSD 400 Neuroplasticity 399

Source coverage 8 active sources

Source	Count	Share	Status
PubMed	2,566	51.7%	Active
OpenAlex	1,155	23.3%	Active
Crossref	405	8.2%	Active
ClinicalTrials.gov	300	6%	Active
Europe PMC	188	3.8%	Active
PsyArXiv	186	3.7%	Active
bioRxiv	123	2.5%	Active

Publication timeline 3,858 dated records

3,858 records since 2020

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Substances Psilocybin 4742 Psilocin 673

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Executed search Sources: PubMed 2,566 matching records are displayed.

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2,566 matching records for Sources: PubMed.

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Consistent evidence that brain serotonin 2A receptor binding is positively associated with personality-based risk markers of depression.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1192/bjp.2024.143 PubMed 39632615

The British journal of psychiatry: the journal of mental science 2025-03-01 Høgsted ES, Beliveau V, Ozenne B, Madsen MK, Svarer C, Dam VH

PubMed Published psilocybin Depression Anxiety Brain Imaging Observational Study More

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Treatment Expectancies and Psilocybin vs Escitalopram for Depression.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1001/jamapsychiatry.2024.4387 PubMed 39653344

JAMA psychiatry 2025-03-01 Dutcher EG, Krystal AD

PubMed Published psilocybin Depression Other More

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The role of the psychedelic experience in psilocybin treatment for treatment-resistant depression.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1016/j.jad.2024.12.061 PubMed 39706482

Journal of affective disorders 2025-03-01 Goodwin GM, Aaronson ST, Alvarez O, Carhart-Harris R, Chai-Rees J, Croal M

PubMed Published psilocybin Depression Pharmacology Mechanism of Action Clinical Trial More

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A systematic review of participant diversity in psychedelic-assisted psychotherapy trials.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1016/j.psychres.2025.116359 PubMed 39823947

Psychiatry research 2025-03-01 Haft SL, Downey AE, Raymond-Flesch M, Fernandes-Osterhold G, Bradley ER, O'Donovan A

PubMed Published psilocybin Clinical Trial Randomized Controlled Trial Systematic Review Randomized Controlled Trial More

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Suicide of a patient shortly after psilocybin-assisted psychedelic therapy: A case report.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1016/j.psychres.2025.116381 PubMed 39889565

Psychiatry research 2025-03-01 Müller F, Sauer T, Hänny C, Mühlhauser M, Lang UE

PubMed Published psilocybin Case Report Case Report More

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The Hallucinogen Rating Scale: Updated Factor Structure in a Large, Multistudy Sample.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1016/j.bpsgos.2024.100436 PubMed 39926700

Biological psychiatry global open science 2025-03-01 Calder AE, Qualls C, Hasler G, Elmiger D, Strassman R

PubMed Published psilocybin Consciousness Other More

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Psilocybin-assisted psychotherapy for Parkinson's disease without depression: A case-report.

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Details DOI 10.1177/1877718x241312604 PubMed 39973494

Journal of Parkinson's disease 2025-03-01 Fleury V, Tomkova E, Catalano Chiuvé S, Penzenstadler L

PubMed Published psilocybin Depression Anxiety Wellbeing Clinical Trial More

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Serotonergic Psychedelics Rapidly Modulate Evoked Glutamate Release in Cultured Cortical Neurons.

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Details DOI 10.1111/jnc.70020 PubMed 40022486

Journal of neurochemistry 2025-03-01 Petrušková A, Guhathakurta D, Akdaş EY, Perelló-Amorós B, Frischknecht R, Weiss EM

PubMed Published psilocybin psilocin Depression Anxiety Addiction Animal Study More

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Therapeutic Potential of Psychedelics for Treating Anosmia: An Investigation of Online Accounts.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1080/02791072.2025.2474239 PubMed 40022524

Journal of psychoactive drugs 2025-03-01 Kovacevich A, Dorney I, Bobak L, Kaelber DC, Barnett BS

PubMed Published psilocybin Mechanism of Action Case Report Case Report More

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Irremediable Psychiatric Suffering, a Potential Indication for Psilocybin Treatment.

No abstract availability was recorded for this entry.

Details DOI 10.1176/appi.ajp.20240121 PubMed 40022534

The American journal of psychiatry 2025-03-01 Somers M, Scheepers FE

PubMed Published psilocybin Depression Other More

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Psychedelics for Cancer Pain and Associated Psychological Distress: A Narrative Review of a Potential Strategy.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1002/cam4.70586 PubMed 40052631

Cancer medicine 2025-03-01 Belitzky E, Ravani Carvalho LV, Taylor M, Ortiz CN, Baum L, Fiellin DA

PubMed Published psilocybin Depression Anxiety Addiction Clinical Trial More

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Psilocybin-Assisted Therapy May Enhance Conservation Values in Patients with Alcohol Use Disorder.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1089/psymed.2024.0030 PubMed 40337752

Psychedelic medicine (New Rochelle, N.Y.) 2025-03-01 Gold ND, Pagni BA, Petridis PD, Bogenschutz MP

PubMed Published psilocybin Addiction Consciousness Personality Change Clinical Trial More

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Participants' Experience of Psychedelic Integration Groups and Processes: A Qualitative Thematic Analysis.

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Details DOI 10.1089/psymed.2024.0027 PubMed 40337755

Psychedelic medicine (New Rochelle, N.Y.) 2025-03-01 Modlin NL, McPhee T, Zazon N, Sarang M, Hignett R, Pick S

PubMed Published psilocybin Aging Clinical Trial Observational Study Clinical Trial More

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Psilocybin-Assisted Psychotherapy for Treatment-Resistant Depression in Bipolar II Disorder.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1089/psymed.2024.0032 PubMed 40337756

Psychedelic medicine (New Rochelle, N.Y.) 2025-03-01 Meshkat S, Kaczmarek E, Doyle Z, Brudner RM, Gomes FA, Blainey MG

PubMed Published psilocybin Depression Treatment-Resistant Depression Safety Other More

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A Field-Wide Review and Analysis of Study Materials Used in Psilocybin Trials: Assessment of Two Decades of Research.

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Details DOI 10.1089/psymed.2024.0019 PubMed 40351554

Psychedelic medicine (New Rochelle, N.Y.) 2025-03-01 Yaden DB, Graziosi M, Owen AM, Agin-Liebes G, Aaronson ST, Allen KE

PubMed Published psilocybin Receptor Pharmacology Consciousness Wellbeing Review Article More

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A Modern Overview of the Potential Therapeutic Effects of Psilocybin in the Treatment of Depressive Disorders, Treatment-Resistant Depression, and End-of-Life Distress.

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Details DOI 10.7759/cureus.80707 PubMed 40242672

Cureus 2025-03-01 Dino F

PubMed Published psilocybin Depression End-of-Life Distress Pharmacology Review Article More

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Anhedonia: Current and future treatments.

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Details DOI 10.1002/pcn5.70088 PubMed 40129874

PCN reports: psychiatry and clinical neurosciences 2025-03-01 Serretti A

PubMed Published psilocybin Depression Pharmacology Receptor Pharmacology Review Article More

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Prolonged adverse effects from repeated psilocybin use in an underground psychedelic therapy training program: a case report.

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Details DOI 10.1186/s12888-024-06303-z PubMed 40021999

BMC psychiatry 2025-02-28 Perna J, Trop J, Palitsky R, Bosshardt Z, Vantine H, Dunlop BW

PubMed Published psilocybin Emotional Processing Case Report Healthcare Workers Case Report More

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Psychedelics and Suicide-Related Outcomes: A Systematic Review.

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Details DOI 10.3390/jcm14051416 PubMed 40094838

Journal of clinical medicine 2025-02-20 Meshkat S, Malik T, Zeifman R, Swainson J, Zhang Y, Burback L

PubMed Published psilocybin PTSD Mechanism of Action Randomized Controlled Trial Randomized Controlled Trial More

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Setting the Stage for the Inner Journey: Unraveling the Interplay of Contextual Factors and the Intensity of Psychedelic-Induced Ego Dissolution.

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Details DOI 10.1080/02791072.2025.2464797 PubMed 39948726

Journal of psychoactive drugs 2025-02-13 Adamczyk S, Paczyńska M, Ruban A, Szczypiński J, Bola M, Orłowski P

PubMed Published psilocybin Emotional Processing Spirituality Observational Study Observational Study More