Loading data...

Psilocybin and psilocin research index

Find psilocybin and psilocin papers, preprints, trials, and citations with clear source context.

Searches titles, authors, journals, identifiers, indexed metadata, and derived research topics. Use Filters to narrow by source, status, substance, study type, or date.

Database 4,967 indexed records Auto-updated on Aug 20, 2026 01:29 UTC

Executed search Evidence: clinical trial 301 matching records are displayed.

Clear search

Database

4,748 Psilocybin Records 673 Psilocin Records 1,461 Journals 66 Research Topics

Published 4,226 Peer-reviewed / formal records Preprints 437 Marked as not peer reviewed Clinical trials 301 ClinicalTrials.gov records R toolkit visNetwork Bibliometrics, live SQLite analysis, HTML graph, and PDF export

Top journals 1,461 indexed journals

Journal	Records
Journal of psychopharmacology (Oxford, England)	148
Journal of psychoactive drugs	97
Frontiers in psychiatry	90
Psychopharmacology	85
Neuroscience Applied	57
Journal of Psychedelic Studies	48
Psychedelic medicine (New Rochelle, N.Y.)	39
Scientific reports	37
Biological Psychiatry	32
Journal of affective disorders	32

Research topics 66 topic filters

Depression 1,738 Receptor Pharmacology 1,282 Safety 1,208 Review Article 1,075 Mechanism of Action 1,072 Clinical Trial 978 Anxiety 884 Addiction 825 Pharmacology 752 General 538 Animal Study 525 Aging 524 Observational Study 516 Brain Imaging 482 Treatment-Resistant Depression 417 Emotional Processing 409 PTSD 401 Neuroplasticity 399

Source coverage 8 active sources

Source	Count	Share	Status
PubMed	2,566	51.7%	Active
OpenAlex	1,156	23.3%	Active
Crossref	407	8.2%	Active
ClinicalTrials.gov	301	6.1%	Active
Europe PMC	188	3.8%	Active
PsyArXiv	186	3.7%	Active
bioRxiv	124	2.5%	Active

Publication timeline 3,864 dated records

3,864 records since 2020

Annual records Cumulative line

Reset all

Keyword search Author

Substances Psilocybin 4748 Psilocin 673

Date range quick select Last month Last year Last 5 years All time Custom range

Executed search Evidence: clinical trial 301 matching records are displayed.

Clear search

Filtered publication index

Search results

301 matching records for Evidence: clinical trial.

Select for export

Effect of Psilocybin and Structured Integrated Reframing Therapy on Gut-Brain Axis Biomarkers and Depression in Trauma-Related Major Depressive Disorder: Randomized Controlled Trial

Abstract available at the source but not redistributed here. Read at source.

Details

ClinicalTrials.gov 2026-07-14 Khyber Medical University Peshawar

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Anxiety PTSD Randomized Controlled Trial More

Select for export

Mechanistic Studies of Psilocybin in Headache Disorders

Abstract available at the source but not redistributed here. Read at source.

Details

ClinicalTrials.gov 2026-07-13 Yale University

ClinicalTrials.gov CLINICAL TRIAL psilocybin Headache / Migraine Neuroplasticity Brain Imaging Clinical Trial More

Select for export

PSilocybin Microdose for psYCHological and Existential Distress in PALliative Care (PSYCHED-PAL): A Multi-site Phase 3 Double-blind, Placebo-controlled, Parallel-arm Clinical Trial

Abstract available at the source but not redistributed here. Read at source.

Details

ClinicalTrials.gov 2026-07-10 Bruyère Health Research Institute.

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Anxiety PTSD Randomized Controlled Trial More

Select for export

PSilocybin for psYCHological and Existential Distress in PALliative Care (PSYCHED-PAL): A Multi-site, Open-label, Single Arm Phase I/II Proof-of-concept, Dose-finding, and Feasibility Clinical Trial

Abstract available at the source but not redistributed here. Read at source.

Details

ClinicalTrials.gov 2026-07-10 Ottawa Hospital Research Institute

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Anxiety End-of-Life Distress Randomized Controlled Trial More

Select for export

Investigating the Mechanisms of the Effects of Psilocybin on Visual Perception and Visual Representations in the Brain

Abstract available at the source but not redistributed here. Read at source.

Details

ClinicalTrials.gov 2026-07-10 University of California, Berkeley

ClinicalTrials.gov CLINICAL TRIAL psilocybin Brain Imaging Mechanism of Action Aging Other More

Select for export

The Effects of Psilocybin on Social Connectedness

Abstract available at the source but not redistributed here. Read at source.

Details

ClinicalTrials.gov 2026-07-09 Yale University

ClinicalTrials.gov CLINICAL TRIAL psilocybin Emotional Processing Clinical Trial More

Select for export

Psilocybin-Assisted Psychotherapy for Treatment-Resistant Depression: A Randomized Phase II Clinical Trial Comparing One Versus Two Psychedelic Doses of Psilocybin (PSI-1V2)

Abstract available at the source but not redistributed here. Read at source.

Details

ClinicalTrials.gov 2026-07-09 University Health Network, Toronto

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Clinical Trial Observational Study Clinical Trial More

Select for export

Computationally, Electrophysiologically, and Qualitatively Characterizing Serotonergic Psychedelics; Transdiagnostic Therapeutic and Pro-Psychotic Effects

Abstract available at the source but not redistributed here. Read at source.

Details

ClinicalTrials.gov 2026-07-09 Yale University

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression PTSD Addiction Clinical Trial More

Select for export

Psilocybin: Capturing Brain Mechanisms of Motivation and Neurocognition in Individuals With Opioid Use Disorder

Abstract available at the source but not redistributed here. Read at source.

Details

ClinicalTrials.gov 2026-07-09 University of Pennsylvania

ClinicalTrials.gov CLINICAL TRIAL psilocybin Addiction Brain Imaging Mechanism of Action Other More

Select for export

Phase I Study of the Safety and Adjunctive Effects of Psilocybin in Adults With Opioid Use Disorder Maintained on a Buprenorphine/Naloxone Formulation

Abstract available at the source but not redistributed here. Read at source.

Details

ClinicalTrials.gov 2026-07-07 University of Wisconsin, Madison

ClinicalTrials.gov CLINICAL TRIAL psilocybin Addiction Chronic Pain Clinical Trial Clinical Trial More

Select for export

Exploration of Synaptotrophic Effects of Psilocybin in Opioid Use Disorder (OUD)

Abstract available at the source but not redistributed here. Read at source.

Details

ClinicalTrials.gov 2026-07-07 Yale University

ClinicalTrials.gov CLINICAL TRIAL psilocybin Addiction Brain Imaging Aging Other More

Select for export

Consciousness and Psilocybin Effects on Well-Being: The CoPEWell Study

Abstract available at the source but not redistributed here. Read at source.

Details

ClinicalTrials.gov 2026-07-02 University of Wisconsin, Madison

ClinicalTrials.gov CLINICAL TRIAL psilocybin Consciousness Wellbeing Psychological Flexibility Other More

Select for export

Efficacy in Relapse Prevention: Psilocybin in Alcohol Use Disorder With Depressive Symptoms

Abstract available at the source but not redistributed here. Read at source.

Details

ClinicalTrials.gov 2026-07-01 Centre Hospitalier Universitaire de Nīmes

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Addiction Safety Other More

Select for export

A Phase 2, Open-Label Study Investigating the Safety and Efficacy of Psilocybin-Assisted Therapy for Sexual Assault-Related Posttraumatic Stress Disorder (PTSD)

Abstract available at the source but not redistributed here. Read at source.

Details

ClinicalTrials.gov 2026-07-01 Sunstone Medical

ClinicalTrials.gov CLINICAL TRIAL psilocybin PTSD Clinical Trial Safety Clinical Trial More

Select for export

5-HT2A Agonist Psilocybin in the Treatment of Tobacco Use Disorder

Abstract available at the source but not redistributed here. Read at source.

Details

ClinicalTrials.gov 2026-06-29 Johns Hopkins University

ClinicalTrials.gov CLINICAL TRIAL psilocybin Addiction Mechanism of Action Receptor Pharmacology Clinical Trial More

Select for export

Psilocybin-Assisted Massed Cognitive Processing Therapy for Chronic Posttraumatic Stress Disorder: An Open-label Trial

Abstract available at the source but not redistributed here. Read at source.

Details

ClinicalTrials.gov 2026-06-26 Unity Health Toronto

ClinicalTrials.gov CLINICAL TRIAL psilocybin PTSD Healthcare Workers Safety Other More

Select for export

Acute Effects of MDMA Co-administration on the Response to Psilocybin in Healthy Subjects

Abstract available at the source but not redistributed here. Read at source.

Details

ClinicalTrials.gov 2026-06-25 University Hospital, Basel, Switzerland

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Anxiety Addiction Qualitative Study More

Select for export

A Pilot Mechanistic RCT of Psilocybin With Mindfulness-based Therapy vs Support for Posttraumatic Stress Disorder (PTSD)

Abstract available at the source but not redistributed here. Read at source.

Details

ClinicalTrials.gov 2026-06-25 Anthony P King

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Anxiety PTSD Randomized Controlled Trial More

Select for export

Effects of Psilocybin Microdosing on Cognition, Mood and Quality of Life: A Pilot Study

Abstract available at the source but not redistributed here. Read at source.

Details

ClinicalTrials.gov 2026-06-23 Yale University

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Brain Imaging Mechanism of Action Other More

Select for export

Psilocybin-assisted Existential, Attachment and Relational (PEARL) Therapy for Caregivers of Patients With Advanced Cancer: A Phase II Open-Label Trial

Abstract available at the source but not redistributed here. Read at source.

Details

ClinicalTrials.gov 2026-06-23 University Health Network, Toronto

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Anxiety End-of-Life Distress Clinical Trial More