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Psilocybin and psilocin research index

Find psilocybin and psilocin papers, preprints, trials, and citations with clear source context.

Searches titles, authors, journals, identifiers, indexed metadata, and derived research topics. Use Filters to narrow by source, status, substance, study type, or date.

Database 4,967 indexed records Auto-updated on Aug 20, 2026 01:29 UTC

Executed search Topic: Neuroplasticity 399 matching records are displayed.

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Database

4,748 Psilocybin Records 673 Psilocin Records 1,461 Journals 66 Research Topics

Published 4,226 Peer-reviewed / formal records Preprints 437 Marked as not peer reviewed Clinical trials 301 ClinicalTrials.gov records R toolkit visNetwork Bibliometrics, live SQLite analysis, HTML graph, and PDF export

Top journals 1,461 indexed journals

Journal	Records
Journal of psychopharmacology (Oxford, England)	148
Journal of psychoactive drugs	97
Frontiers in psychiatry	90
Psychopharmacology	85
Neuroscience Applied	57
Journal of Psychedelic Studies	48
Psychedelic medicine (New Rochelle, N.Y.)	39
Scientific reports	37
Biological Psychiatry	32
Journal of affective disorders	32

Research topics 66 topic filters

Depression 1,738 Receptor Pharmacology 1,282 Safety 1,208 Review Article 1,075 Mechanism of Action 1,072 Clinical Trial 978 Anxiety 884 Addiction 825 Pharmacology 752 General 538 Animal Study 525 Aging 524 Observational Study 516 Brain Imaging 482 Treatment-Resistant Depression 417 Emotional Processing 409 PTSD 401 Neuroplasticity 399

Source coverage 8 active sources

Source	Count	Share	Status
PubMed	2,566	51.7%	Active
OpenAlex	1,156	23.3%	Active
Crossref	407	8.2%	Active
ClinicalTrials.gov	301	6.1%	Active
Europe PMC	188	3.8%	Active
PsyArXiv	186	3.7%	Active
bioRxiv	124	2.5%	Active

Publication timeline 3,864 dated records

3,864 records since 2020

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Substances Psilocybin 4748 Psilocin 673

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Executed search Topic: Neuroplasticity 399 matching records are displayed.

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399 matching records for Topic: Neuroplasticity.

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Altered States of Consciousness and the Subconscious Mind: A Comprehensive Comparative Review of Disciplines, Neurobiological Mechanisms, Clinical Applications, and Philosophical Frameworks - Including Life Between Lives and Transpersonal Hypnotherapy

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.20944/preprints202604.0415.v1

Preprints.org 2026-04-07 Gallardo LM.

Europe PMC PREPRINT (not peer reviewed) psilocybin Depression Anxiety PTSD Randomized Controlled Trial More

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Psilocybin mitigates chronic behavioral and neurobiological alterations in a rat model of recurrent intimate partner violence-related brain injury.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1038/s41380-025-03329-x PubMed 41193674

Molecular psychiatry 2026-04-01 Allen J, Sun M, Baker TL, Dames S, Kryskow P, Christie BR

PubMed Published psilocybin Neuroplasticity Receptor Pharmacology Animal Study Animal Study More

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Classic psychedelics in obsessive-compulsive disorder: a circuit-based framework

No abstract availability was recorded for this entry.

Details DOI 10.1038/s44220-026-00626-4

Nature Mental Health 2026-03-31 Saif S. Ali, Robin L. Carhart-Harris, Karl G. Sieg

OpenAlex Published psilocybin Addiction OCD Chronic Pain Other More

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Reshaping human neurons.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.7554/elife.110981 PubMed 41914141

eLife 2026-03-31 Maltman JL, González-Maeso J

PubMed Published psilocybin psilocin Neuroplasticity Receptor Pharmacology Transcriptomics Other More

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Therapeutic Potential of Classical Psychedelics and NonHallucinogenic Psychoplastogens in Psychiatric Disorders

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.65801/pcp.3512

Psychiatry and Clinical Psychopharmacology 2026-03-30 Kenji Hashimoto, Feyza Arıcıoğlu, Mesut Çetin

OpenAlex Published psilocybin Depression Addiction Neuroplasticity Randomized Controlled Trial More

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Psilocin fosters neuroplasticity in iPSC-derived human cortical neurons

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.7554/elife.104006 PubMed 41891829

eLife 2026-03-27 Schmidt Malin, Hoffrichter Anne, Davoudi Mahnaz, Horschitz Sandra, Lau Thorsten, Meinhardt Marcus W

Crossref Published psilocybin psilocin Depression Anxiety Neuroplasticity Other More

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Psychedelic-Induced Constraint Destabilization and Reconstruction as a Mechanism for Cognitive Reset

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.5281/zenodo.19221582

Zenodo (CERN European Organization for Nuclear Research) 2026-03-25 Stanley Everett Sambey

OpenAlex Published psilocybin Neuroplasticity Brain Imaging Default Mode Network Other More

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Elucidating the Relevance of the Psychedelic Experience to Psilocybin's Anti-Anhedonic Effects: A Randomized, Open-Label, Cross-Over Functional Magnetic Resonance Imaging Trial

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ClinicalTrials.gov 2026-03-24 Medical University of Vienna

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Neuroplasticity Brain Imaging Clinical Trial More

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Integrated 5-HT -TrkB and G protein signaling in serotonergic psychedelic responses.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.64898/2026.03.19.712961 PubMed 41928993

bioRxiv: the preprint server for biology 2026-03-23 Taddei-Tardón M, Medina-Rodríguez L, Maltman JL, Hudson S, Potukanuma S, Jiménez JH

PubMed Published psilocin Neuroplasticity Pharmacology Mechanism of Action In Vitro Study More

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Precision Phenotyping of Behavioral Risk and Response to Electromagnetic and Psychedelic Therapies

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ClinicalTrials.gov 2026-03-20 University of New Mexico

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression PTSD Neuroplasticity Observational Study More

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Psychedelics and Mental Health in Endurance Athletes: A Cross-Sectional Study in Brazil.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1080/02791072.2026.2644865 PubMed 41860795

Journal of psychoactive drugs 2026-03-20 Portes MAM, Bertoglio LJ

PubMed Published psilocybin Depression Anxiety PTSD Observational Study More

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Beyond the Genomic Storm: Evaluating Tabernanthalog as a Potential Scaffold for Silent Neuroplasticity and Broad-Spectrum Therapy.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.3390/ijms27062811 PubMed 41898671

International journal of molecular sciences 2026-03-20 Anchesi I, Raffaele I, Astorino MF, Lui M, Calabrò M, Cipriano GL

PubMed Published psilocybin End-of-Life Distress Chronic Pain Neuroplasticity Review Article More

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PSILOCYBIN AS AN ADJUNCTIVE TREATMENT FOR DEPRESSION AND PSYCHOLOGICAL DISTRESS IN ONCOLOGY: CURRENT EVIDENCE AND CLINICAL IMPLICATIONS

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.31435/ijitss.1(49).2026.5034

International Journal of Innovative Technologies in Social Science 2026-03-19 Komarczewska Anna, Kociński Michał, Iglewski Patryk, Pietrasz Michał, Idziński Jakub, Lubomska Anna

Crossref Published psilocybin Depression Anxiety End-of-Life Distress Randomized Controlled Trial More

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Editorial: Psychedelic substances and neurological diseases: from basics to clinical application

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.3389/fphar.2026.1816812 PubMed 41919223

Frontiers in Pharmacology 2026-03-15 Alessandra Linardi, Ariadiny Lima Caetano, Rodrigo Portes Ureshino

OpenAlex Published psilocybin Depression Anxiety PTSD Clinical Trial More

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The renaissance of research on psychedelics in child and adolescent psychopharmacology.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1186/s13034-026-01069-6 PubMed 41826990

Child and adolescent psychiatry and mental health 2026-03-13 Crocq MA, Auby P

PubMed Published psilocybin Depression PTSD OCD Clinical Trial More

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Strategic Neurodelivery of Psychedelic Compounds: Bridging Molecular Pharmacology with Therapeutic Innovation in CNS Disorders.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.2174/0118715273434237251212095005 PubMed 41833044

CNS & neurological disorders drug targets 2026-03-11 Chauhan SB, Akhtar N, Jain C, Singh I

PubMed Published psilocybin Depression PTSD Addiction Other More

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Enhancing cGMP signaling with psilocybin reduces head twitch and restructures the synaptic proteome while maintaining antidepressant response

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Details DOI 10.64898/2026.03.06.710108

bioRxiv 2026-03-10 Floris G, Jefferson SJ, Rondeau J, Yu AL, Menniti FS, Kwan AC

bioRxiv PREPRINT (not peer reviewed) psilocybin Neuroplasticity Mechanism of Action Receptor Pharmacology Other More

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“Diversity makes the richness of humanity”: The emergence and persistence of mental imagery after self-reported psilocybin truffles intake in an autistic woman with “blind imagination” (aphantasia): A33-month retrospective case report

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1556/2054.2025.00320

Journal of Psychedelic Studies 2026-03-09 Rebecchi Kevin

Crossref Published psilocybin Neuroplasticity Aging Case Report Case Report More

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The combination of exercise and psychedelics for the treatment of major depressive disorder.

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Details DOI 10.1007/s44192-026-00408-5 PubMed 41793582

Discover mental health 2026-03-07 Fabiano N, Stubbs B, Lawrence DW, Rosenblat JD, Teixeira PJ, Wong S

PubMed Published psilocybin Depression Neuroplasticity Neurogenesis Other More

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Inhibition of cortico-amygdala projections underlies affective bias modification by psilocybin

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Details DOI 10.64898/2026.03.02.709133

bioRxiv 2026-03-04 Claydon MDB, Hinchcliffe JK, Bartlett J, Golden CT, Thomas CW, Gilmour G

bioRxiv PREPRINT (not peer reviewed) psilocybin psilocin Depression Neuroplasticity Mechanism of Action Animal Study More