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Psilocybin and psilocin research index

Find psilocybin and psilocin papers, preprints, trials, and citations with clear source context.

Searches titles, authors, journals, identifiers, indexed metadata, and derived research topics. Use Filters to narrow by source, status, substance, study type, or date.

Database 4,967 indexed records Auto-updated on Aug 20, 2026 01:29 UTC

Executed search Study type: Clinical Trial 952 matching records are displayed.

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Database

4,748 Psilocybin Records 673 Psilocin Records 1,461 Journals 66 Research Topics

Published 4,226 Peer-reviewed / formal records Preprints 437 Marked as not peer reviewed Clinical trials 301 ClinicalTrials.gov records R toolkit visNetwork Bibliometrics, live SQLite analysis, HTML graph, and PDF export

Top journals 1,461 indexed journals

Journal	Records
Journal of psychopharmacology (Oxford, England)	148
Journal of psychoactive drugs	97
Frontiers in psychiatry	90
Psychopharmacology	85
Neuroscience Applied	57
Journal of Psychedelic Studies	48
Psychedelic medicine (New Rochelle, N.Y.)	39
Scientific reports	37
Biological Psychiatry	32
Journal of affective disorders	32

Research topics 66 topic filters

Depression 1,738 Receptor Pharmacology 1,282 Safety 1,208 Review Article 1,075 Mechanism of Action 1,072 Clinical Trial 978 Anxiety 884 Addiction 825 Pharmacology 752 General 538 Animal Study 525 Aging 524 Observational Study 516 Brain Imaging 482 Treatment-Resistant Depression 417 Emotional Processing 409 PTSD 401 Neuroplasticity 399

Source coverage 8 active sources

Source	Count	Share	Status
PubMed	2,566	51.7%	Active
OpenAlex	1,156	23.3%	Active
Crossref	407	8.2%	Active
ClinicalTrials.gov	301	6.1%	Active
Europe PMC	188	3.8%	Active
PsyArXiv	186	3.7%	Active
bioRxiv	124	2.5%	Active

Publication timeline 3,864 dated records

3,864 records since 2020

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Substances Psilocybin 4748 Psilocin 673

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Executed search Study type: Clinical Trial 952 matching records are displayed.

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952 matching records for Study type: Clinical Trial.

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Exploring the Safety, Acceptability, and Efficacy of Psilocybin Among Non-Small Cell Lung Cancer Patients With Major Depressive Disorder: A Proof-of-Concept Trial (DREAM LUNG STUDY)

Abstract available at the source but not redistributed here. Read at source.

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ClinicalTrials.gov 2026-05-14 Alan Davis

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Anxiety Clinical Trial Clinical Trial More

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Psilocybin for Treatment of Obsessive Compulsive Disorder

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ClinicalTrials.gov 2026-05-12 Francisco A Moreno

ClinicalTrials.gov CLINICAL TRIAL psilocybin OCD Brain Imaging Consciousness Clinical Trial More

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From Trials to Clinics: Considerations for Implementing Psychedelic-Assisted Therapy Into Clinical Practice

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1002/prp2.70262 PubMed 42108552

Pharmacology Research & Perspectives 2026-05-10 Jessie Kim, Liam Lochhead, Cory R. Weissman

OpenAlex Published psilocybin Depression Neuroplasticity Mechanism of Action Clinical Trial More

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The Safety and Efficacy of Psilocybin Therapy Compared to Low-dose Control in Reducing Depressive Symptoms in Patients With COPD, ALS, MS, or APD.

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ClinicalTrials.gov 2026-05-08 University Medical Center Groningen

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Anxiety End-of-Life Distress Clinical Trial More

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1080 Psilocybin Elicits Non-Linear Night to Night Changes in Sleep Spectral Power

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1093/sleep/zsag091.1079

SLEEPJ 2026-05-08 Reid Matthew, Weisman Eli, Martinez Luis Luna, Coon William, Barrett Frederick

Crossref Published psilocybin Depression Addiction Brain Imaging Clinical Trial More

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Psilocybin-Assisted Therapy in Depressive Disorders: Efficacy, Safety, and Persistence of Clinical Effects - A Narrative Review

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.12775/jehs.2026.91.70672

Journal of Education, Health and Sport 2026-05-07 Zachar Kinga, Sito Maksymilian, Jurkowski Filip, Wójcik Łukasz, Gawron Natalia, Bojanowski Hubert Tomasz

Crossref Published psilocybin Depression Anxiety Headache / Migraine Clinical Trial More

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Psilocybin in the Treatment of Cocaine Use Disorder

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1001/jamanetworkopen.2026.11029 PubMed 42096204

JAMA Network Open 2026-05-07 Hendricks Peter S., Lappan Sara N., Shelton Richard C., Lahti Adrienne C., Cropsey Karen L., Johnson Matthew W.

Crossref Published psilocybin Addiction Clinical Trial Safety Clinical Trial More

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A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of up to Two Doses of Psilocybin for the Treatment of Major Depressive Disorder in Adults With Cancer

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ClinicalTrials.gov 2026-05-06 Sunstone Medical

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Clinical Trial Observational Study Clinical Trial More

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Induction Protocol for Psilocybin-Assisted Therapy in Treatment-Resistant Depression (TRD): A Pilot Study

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ClinicalTrials.gov 2026-05-06 University of North Carolina, Chapel Hill

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Clinical Trial Observational Study Clinical Trial More

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A Phase 2 Randomized Study Examining the Safety, Feasibility, and Effectiveness of Masking Psilocybin Therapy With General Anesthesia in Major Depressive Disorder

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ClinicalTrials.gov 2026-05-06 Stanford University

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Anxiety Brain Imaging Clinical Trial More

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A One-Year Observational Follow-up Study of Participants With Major Depressive Disorder Following a Randomized, Double-Blind Single-Dose of Psilocybin or Niacin-Control

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ClinicalTrials.gov 2026-05-04 Usona Institute

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Clinical Trial Observational Study Clinical Trial More

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A Phase 2 Sequential Dose-Finding Study of Preparation for Group Retreat Psilocybin Therapy for Healthcare Clinicians With Loss of Meaning in Their Work and Symptoms of Depression

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ClinicalTrials.gov 2026-05-04 University of Washington

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Anxiety Clinical Trial Clinical Trial More

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356. Psilocybin Therapy is Associated With Decreases in Markers of Mitochondrial Stress and Inflammation in an Open-Label Clinical Trial of Parkinson’s Disease

No abstract availability was recorded for this entry.

Details DOI 10.1016/j.biopsych.2026.03.590

Biological Psychiatry 2026-05-01 Bradley Ellen, Kelley D Parker, Picard Martin, Szigeti Balazs, Sakai Kimberly, Fernandes Gisele

Crossref Published psilocybin Biomarkers Mitochondrial Function Clinical Trial Clinical Trial More

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Landscape analysis of pre-registered clinical trials involving classical psychedelics.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1177/02698811251371690 PubMed 41121524

Journal of psychopharmacology (Oxford, England) 2026-05-01 Uyar A, Forbrich L, Lueken U, Evens R

PubMed Published psilocybin Clinical Trial Review Article Clinical Trial More

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The 3D-ASCr scale: A revalidation of the core dimensions of the Altered States of Consciousness Rating Scale 5D(11)-ASC for psychedelic research.

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Details DOI 10.1177/02698811251397328 PubMed 41451514

Journal of psychopharmacology (Oxford, England) 2026-05-01 Stocker K, Hartmann M, Schmid Y, Vogt SB, Becker AM, Ley L

PubMed Published psilocybin Anxiety Consciousness Healthy Volunteers Clinical Trial More

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The effects of psilocybin on time perception in humans: A comparative analysis of subjective and objective measures.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1177/02698811251389552 PubMed 41479142

Journal of psychopharmacology (Oxford, England) 2026-05-01 Scholle P, Wenke Š, Nekovářová T, Zaytseva Y, Tylš F, Brunovský M

PubMed Published psilocybin Consciousness Clinical Trial Healthy Volunteers Clinical Trial More

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Effects of psilocybin on personality, psychiatric symptoms, and values: Exploring mediating effects of the acute psychedelic experience.

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Details DOI 10.1177/02698811251408769 PubMed 41588876

Journal of psychopharmacology (Oxford, England) 2026-05-01 Kerr-Gaffney J, Myrtle S, Askari F, Bird C, Modlin NL, Young AH

PubMed Published psilocybin Consciousness Wellbeing Personality Change Clinical Trial More

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Challenges with clinical trial participants in studies with classical psychedelics: A position statement from the National Network of Depression Centers' task group on psychedelics and related compounds.

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Details DOI 10.1177/02698811251413490 PubMed 41645048

Journal of psychopharmacology (Oxford, England) 2026-05-01 Lewis BR, Reid MJ, Novick AM, Byrne K, Niciu MJ, Fonzo GA

PubMed Published psilocybin Depression Clinical Trial Healthcare Workers Clinical Trial More

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Trip sitting or just sitting? Session facilitators substantially influence psychedelic experiences in clinical trials but not in healthy ones.

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Details DOI 10.1016/j.psychres.2026.117010 PubMed 41747432

Psychiatry research 2026-05-01 Goldy SP, Sepeda ND, Hilbert SN, Bari BA, Garcia-Romeu A, Gukasyan N

PubMed Published psilocybin Depression Anxiety Clinical Trial Clinical Trial More

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A randomized clinical trial of repeated doses of psilocybin for the treatment of obsessive-compulsive disorder

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Details DOI 10.1177/02698811261424214 PubMed 41825921

Journal of Psychopharmacology 2026-05-01 Moreno Francisco A., Allen Katja E., Wiegand Christopher B., Dunne Rajan, Prickett James I., Bayze Brian

Crossref Published psilocybin OCD Receptor Pharmacology Clinical Trial Clinical Trial More