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Psilocybin and psilocin research index

Find psilocybin and psilocin papers, preprints, trials, and citations with clear source context.

Searches titles, authors, journals, identifiers, indexed metadata, and derived research topics. Use Filters to narrow by source, status, substance, study type, or date.

Database 4,967 indexed records Auto-updated on Aug 20, 2026 01:29 UTC

Executed search Topic: Clinical Trial 978 matching records are displayed.

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Database

4,748 Psilocybin Records 673 Psilocin Records 1,461 Journals 66 Research Topics

Published 4,226 Peer-reviewed / formal records Preprints 437 Marked as not peer reviewed Clinical trials 301 ClinicalTrials.gov records R toolkit visNetwork Bibliometrics, live SQLite analysis, HTML graph, and PDF export

Top journals 1,461 indexed journals

Journal	Records
Journal of psychopharmacology (Oxford, England)	148
Journal of psychoactive drugs	97
Frontiers in psychiatry	90
Psychopharmacology	85
Neuroscience Applied	57
Journal of Psychedelic Studies	48
Psychedelic medicine (New Rochelle, N.Y.)	39
Scientific reports	37
Biological Psychiatry	32
Journal of affective disorders	32

Research topics 66 topic filters

Depression 1,738 Receptor Pharmacology 1,282 Safety 1,208 Review Article 1,075 Mechanism of Action 1,072 Clinical Trial 978 Anxiety 884 Addiction 825 Pharmacology 752 General 538 Animal Study 525 Aging 524 Observational Study 516 Brain Imaging 482 Treatment-Resistant Depression 417 Emotional Processing 409 PTSD 401 Neuroplasticity 399

Source coverage 8 active sources

Source	Count	Share	Status
PubMed	2,566	51.7%	Active
OpenAlex	1,156	23.3%	Active
Crossref	407	8.2%	Active
ClinicalTrials.gov	301	6.1%	Active
Europe PMC	188	3.8%	Active
PsyArXiv	186	3.7%	Active
bioRxiv	124	2.5%	Active

Publication timeline 3,864 dated records

3,864 records since 2020

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Substances Psilocybin 4748 Psilocin 673

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Executed search Topic: Clinical Trial 978 matching records are displayed.

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978 matching records for Topic: Clinical Trial.

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Study of Psilocybin Assisted Psychotherapy to Address Fear of Recurrence in Patients Diagnosed With Early-stage Breast Cancer and Ovarian Cancer in Remission

Abstract available at the source but not redistributed here. Read at source.

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ClinicalTrials.gov 2026-04-21 University of Colorado, Denver

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Anxiety Clinical Trial Clinical Trial More

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The efficacy and safety of psilocybin-assisted therapy for major depressive disorder: a meta-analytic review of clinical outcomes

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.4081/mw.2026.40

Mental Wellness 2026-04-21 Khosravi Mohsen, De Berardis Domenico, Tusconi Massimo

Crossref Published psilocybin Depression Clinical Trial Meta-Analysis Meta-Analysis More

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Efficacy and Safety of Psilocybin-Assisted Therapy for Depression: A Meta-Analysis of Randomised Controlled Trials

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.37275/oaijmr.v6i2.883

Open Access Indonesian Journal of Medical Reviews 2026-04-21 Siti Nashria Rusdhy, Andrian Fajar Kusumadewi, Carla Raymondalexas Marchira, Mustika Suci Mahardikaningrum, Teresa Lalita Wiryarini, Devira Ayu Wulandari

Crossref Published psilocybin Depression Clinical Trial Randomized Controlled Trial Randomized Controlled Trial More

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Sustained Effects of Low-to-Moderate Doses of Psilocybin on Brain Connectivity

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.64898/2026.04.17.26351147

medRxiv 2026-04-20 Bhagavan C, Dandash O, Carter O, Bryson A, Kanaan RA.

medRxiv PREPRINT (not peer reviewed) psilocybin Brain Imaging Consciousness Aging Clinical Trial More

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Psychedelics and Autism Therapy: A Review of Current Research and Future Directions.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.3390/cimb48040417 PubMed 42042077

Current issues in molecular biology 2026-04-18 Gondi CS, Gnanamony M, Gondi TP, Nersesyan L, Demirkhanyan L

PubMed Published psilocybin Depression PTSD Neuroplasticity Clinical Trial More

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Psilocybin’s Kinematic Effect on Manual Dexterity

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.21203/rs.3.rs-9291780/v1

Research Square 2026-04-15 Klintefors P, Bhagavan C, Kanaan R, Bryson A, Berlowitz D, Attard Z

Europe PMC PREPRINT (not peer reviewed) psilocybin Clinical Trial Review Article Healthy Volunteers Clinical Trial More

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A phase 1 study of a second experience with Group Retreat Psilocybin Therapy for partial responders after a first experience

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.3389/fpubh.2026.1810904 PubMed 42058096

Frontiers in Public Health 2026-04-14 Back Anthony L., McGregor Bonnie A., Thorn Leslie L., Harvey Kalin, Blom Dianna, Callan George

Crossref Published psilocybin Depression Anxiety Headache / Migraine Clinical Trial More

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CAPSI - Cancer Related Major Depression Treated With a Single Dose of Psilocybin: A Multicenter Randomized Placebo Controlled Double Blind Clinical Trial

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ClinicalTrials.gov 2026-04-13 Section for Affective Disorders; Northern Stockholm Psychiatry

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Clinical Trial Clinical Trial More

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Acute Analgesic Effects of DMT on Experimentally Induced Acute Nociceptive Pain, Hyperalgesia and Allodynia in Healthy Participants

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ClinicalTrials.gov 2026-04-02 University Hospital, Basel, Switzerland

ClinicalTrials.gov CLINICAL TRIAL psilocybin Chronic Pain Headache / Migraine Clinical Trial Clinical Trial More

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Comparing single- and repeat-dose psilocybin with active placebo for migraine prevention in an exploratory randomized controlled clinical trial.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1111/head.70024 PubMed 41459830

Headache 2026-04-01 Schindler EAD, Gottschalk CH, Pittman BP, D'Souza DC

PubMed Published psilocybin Headache / Migraine Clinical Trial Randomized Controlled Trial Randomized Controlled Trial More

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Psilocybin Production With Genetically Modified Aspergillus nidulans Under Pressurized Conditions.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1002/bit.70137 PubMed 41467547

Biotechnology and bioengineering 2026-04-01 Weiser S, Jung S, Bardl B, Kufs JE, Janevska S, Valiante V

PubMed Published psilocybin Clinical Trial Clinical Trial More

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Bridging the reporting gap: Application of the ReSPCT guidelines in psilocybin clinical trial protocols

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1016/j.euroneuro.2025.112746 PubMed 41546918

European Neuropsychopharmacology 2026-04-01 Swieczkowski Damian, Kwaśny Aleksander, Sadko Krzysztof, Cubała Wiesław Jerzy

Crossref Published psilocybin Clinical Trial Clinical Trial More

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Effects of psilocybin and chronic mild stress on microglial activation in rat spinal cord: an ex vivo analysis.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1007/s43440-026-00824-y PubMed 41557251

Pharmacological reports: PR 2026-04-01 Olejnik P, Kamińska K, Gołembiowska K, Kasarełło K

PubMed Published psilocybin Biomarkers Clinical Trial Animal Study Clinical Trial More

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Consistency of protocol and safety data reporting in clinical trial registrations and corresponding publications of interventions involving MDMA and psilocybin

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1016/j.jclinepi.2026.112170 PubMed 41581835

Journal of Clinical Epidemiology 2026-04-01 Žuljević Marija Franka, Mijatović Antonija, Orhanović Renata, Goasdoué Glenn, Gujinović Diana

Crossref Published psilocybin Clinical Trial Safety Clinical Trial More

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PSilocybin for psYCHological and existential distress in PALliative care (PSYCHED-PAL): A single arm unblinded clinical trial.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1177/02692163261416269 PubMed 41617652

Palliative medicine 2026-04-01 Downar J, Lapenskie J, Anderson K, Parsons G, Polskaia N, Lalumiere G

PubMed Published psilocybin Depression Anxiety End-of-Life Distress Clinical Trial More

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Psychedelic Therapies for Comorbid Major Depressive Disorder and Chronic Pain: A Review of Putative Mechanisms of Action.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1002/prp2.70238 PubMed 41940853

Pharmacology research & perspectives 2026-04-01 Kazdan J, Ladha KS, Husain MI

PubMed Published psilocybin Depression Chronic Pain Mechanism of Action Clinical Trial More

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Psychedelic-assisted pharmacotherapy: clinical applications and regulatory considerations.

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Details DOI 10.1080/14656566.2026.2654682 PubMed 41944071

Expert opinion on pharmacotherapy 2026-04-01 Marazziti D, Gambini M, Gurrieri R, Russomanno G, Sità G, Pescini E

PubMed Published psilocybin Depression Anxiety PTSD Clinical Trial More

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Therapeutic Potential of Classical Psychedelics and NonHallucinogenic Psychoplastogens in Psychiatric Disorders

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.65801/pcp.3512

Psychiatry and Clinical Psychopharmacology 2026-03-30 Kenji Hashimoto, Feyza Arıcıoğlu, Mesut Çetin

OpenAlex Published psilocybin Depression Addiction Neuroplasticity Randomized Controlled Trial More

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Engaging Mood Brain Circuits With Psilocybin: a Randomized Neuroimaging Trial in Depression

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ClinicalTrials.gov 2026-03-30 Sunnybrook Health Sciences Centre

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Brain Imaging Aging Clinical Trial More

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Psilocybin Assisted Psychotherapy for Treatment Resistant Depression and Co-occurring Substance Use Disorder

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Details

ClinicalTrials.gov 2026-03-30 Indiana University

ClinicalTrials.gov CLINICAL TRIAL psilocybin Depression Addiction Brain Imaging Clinical Trial More