Researcher index

Authors in the psilocybin and psilocin literature

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Charles D. Nichols

45 indexed publications match this author name.

ORCID: 0000-0002-0615-0646
OpenAlex: https://openalex.org/A5062966169

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Topics

Receptor Pharmacology 26 Depression 21 Mechanism of Action 15 Pharmacology 14 Clinical Trial 14 Anxiety 11 Animal Study 10 Addiction 10 Review Article 8 Aging 7 Inflammation 7 Neuroplasticity 6

Journals

The FASEB Journal 4 Neuropharmacology 3 Pharmacological reviews 2 Psychedelic medicine (New Rochelle, N.Y.) 2 Current topics in behavioral neurosciences 2 ACS chemical neuroscience 2 Psychopharmacology 2 Pharmacology, biochemistry, and behavior 2

Publication history

Chemistry/structural biology of psychedelic drugs and their receptor(s).British journal of pharmacology · 2026-07-01 Psychedelics produce enduring behavioral effects and functional plasticity through mechanisms independent of structural plasticity.Neuropsychopharmacology: official publication of the American College of Neuropsychopharmacology · 2026-02-01 Preadministration of Lorazepam Negates the Long-Term Antidepressant-Like Effects of Psilocybin in Male Wistar Kyoto RatsPsychedelic Medicine · 2025-12-16 The polypharmacology of psychedelics reveals multiple targets for potential therapeutics.Neuron · 2025-10-01 5-HT receptors: Pharmacology and functional selectivity.Pharmacological reviews · 2025-07-01 The Selective Serotonin 5-HT Receptor Agonist ()-3-(2,5-Dimethoxy-4-(trifluoromethyl)phenyl)piperidine (LPH-5) Induces Persistent and Robust Antidepressant-Like Effects in Rodents.ACS pharmacology & translational science · 2025-06-13 Probing the functional magnetic resonance imaging response to psilocybin in functional neurological disorder (PsiFUND): study protocolWellcome Open Res · 2024-07-24 Structure of a Hallucinogen-Activated Gq-Coupled 5-HT2A Serotonin ReceptorUNC Libraries · 2024-06-07 The selective 5-HT2A receptor agonist LPH-5 induces persistent and robust antidepressant-like effects in rodentsbioRxiv · 2024-04-22 Preadministration of Lorazepam Reduces Efficacy and Longevity of Antidepressant-Like Effect from a Psychedelic.Psychedelic medicine (New Rochelle, N.Y.) · 2024-03-01 Probing the functional magnetic resonance imaging response to psilocybin in functional neurological disorder (PsiFUND): study protocol.Wellcome open research · 2024-01-01 Preclinical perspectives on the mechanisms underlying the therapeutic actions of psilocybin in psychiatric disorders.Neuropharmacology · 2023-06-15 A Single Administration of Psilocybin Persistently Rescues Cognitive Deficits Caused by Adolescent Chronic Restraint Stress Without Long-Term Changes in Synaptic Protein Gene Expression in a Rat Experimental System with Translational Relevance to Depression.Psychedelic medicine (New Rochelle, N.Y.) · 2023-03-01 Psychedelic drug abuse potential assessment research for new drug applications and Controlled Substances Act scheduling.Neuropharmacology · 2022-11-01 Molecular Structure, Reactivity and Spectroscopic Properties of Hallucinogens Psilocybin, Mescaline and their Derivatives - A Computational StudyLetters in Applied NanoBioScience · 2022-09-17 Psychedelics as potent anti-inflammatory therapeuticsNeuropharmacology · 2022-08-22 From psychiatry to neurology: Psychedelics as prospective therapeutics for neurodegenerative disorders.Journal of neurochemistry · 2022-07-01 Validation of the forced swim test in Drosophila, and its use to demonstrate psilocybin has long-lasting antidepressant-like effects in flies.Scientific reports · 2022-06-15 Psychedelics and Anti-inflammatory Activity in Animal Models.Current topics in behavioral neurosciences · 2022-01-01 Psilocybin: from ancient magic to modern medicine.The Journal of antibiotics · 2020-10-01 One Dose of Psilocybin in Late Adolescence Mitigates Deleterious Effects of Developmental Stress on Cognition and Behavioral Despair in Adult Female RatsThe FASEB Journal · 2020-03-31 Psychedelics, but Not Ketamine, Produce Persistent Antidepressant-like Effects in a Rodent Experimental System for the Study of Depression.ACS chemical neuroscience · 2020-03-18 Psychedelic treatment of functional neurological disorder: a systematic review.Therapeutic advances in psychopharmacology · 2020-01-01 Microdosing psychedelics: More questions than answers? An overview and suggestions for future research.Journal of psychopharmacology (Oxford, England) · 2019-09-01 Psychedelics Improve the Mental Health of RatsThe FASEB Journal · 2019-04-01 Population Survey Data Informing the Therapeutic Potential of Classic and Novel Phenethylamine, Tryptamine, and Lysergamide Psychedelics.Frontiers in psychiatry · 2019-01-01 Dark Classics in Chemical Neuroscience: Lysergic Acid Diethylamide (LSD).ACS chemical neuroscience · 2018-10-17 Psychedelics as anti-inflammatory agents.International review of psychiatry (Abingdon, England) · 2018-08-01 The Effects of Hallucinogens on Gene Expression.Current topics in behavioral neurosciences · 2018-01-01 Psychedelic Drugs in Biomedicine.Trends in pharmacological sciences · 2017-11-01 Anti-inflammatory effects of serotonin 5-HT2A receptor activation in ovalbumin-induced allergic asthma modelsThe FASEB Journal · 2017-04-01 Psychedelics as Medicines: An Emerging New Paradigm.Clinical pharmacology and therapeutics · 2017-02-01 Psychedelics.Pharmacological reviews · 2016-04-01 The Heffter Research Institute: past and hopeful future.Journal of psychoactive drugs · 2014-01-01 Dopamine D4 receptor involvement in the discriminative stimulus effects in rats of LSD, but not the phenethylamine hallucinogen DOIPsychopharmacology · 2008-07-04 Further evidence that the delayed temporal dopaminergic effects of LSD are mediated by a mechanism different than the first temporal phase of action.Pharmacology, biochemistry, and behavior · 2007-10-01 Commentary on: Psilocybin can occasion mystical-type experiences having substantial and sustained personal meaning and spiritual significance by Griffiths et al.Psychopharmacology · 2006-07-05 Effects of the N343A mutation in TM6 of the human serotonin 5-HT2A ReceptorThe FASEB Journal · 2006-03-01 Effect of ring fluorination on the pharmacology of hallucinogenic tryptamines.Journal of medicinal chemistry · 2000-11-30 Further studies on oxygenated tryptamines with LSD-like activity incorporating a chiral pyrrolidine moiety into the side chain.Journal of medicinal chemistry · 1999-10-07 ChemInform Abstract: Improvements to the Synthesis of Psilocybin and a Facile Method for Preparing the O-Acetyl Prodrug of Psilocin.ChemInform · 1999-08-17 Improvements to the Synthesis of Psilocybin and a Facile Method for Preparing the O-Acetyl Prodrug of PsilocinSynthesis · 1999-06-01 Studies of the relationship between molecular structure and hallucinogenic activity.Pharmacology, biochemistry, and behavior · 1986-02-01 ChemInform Abstract: COMPARISON OF SOLUTION CONFORMATIONAL PREFERENCES FOR THE HALLUCINOGENS BUFOTENIN AND PSILOCIN USING 360-MHZ PROTON NMR SPECTROSCOPYChemischer Informationsdienst · 1981-07-14 Comparison of solution conformational preferences for the hallucinogens bufotenin and psilocin using 360-MHz proton NMR spectroscopyJournal of Medicinal Chemistry · 1981-02-01

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