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Single-crystal structure determination of psilocybin after dehydrationActa Crystallographica Section C Structural Chemistry · 2026-09-01A Multi-site Randomized Controlled Trial of Psilocybin for Treatment-Resistant Depression (TRD) in VeteransClinicalTrials.gov · 2026-08-14Exploring the In Vitro Effect of Psilocybin on the Composition and Metabolic Activity of Gut Microbiota in Individuals with Severe AnxietyDrugs and Drug Candidates · 2026-08-12Feasibility Phase 2 Study of Psilocybin-Assisted Therapy for Opioid-Refractory Pain in Patients With Advanced CancerClinicalTrials.gov · 2026-08-05Music for Psilocybin Therapy and the Temporal Arc of Psychedelic ExperienceResearch Square · 2026-08-03A cross-national comparison of nonmedical and medical use of psychedelic drugs in the international cannabis policy study.The International journal on drug policy · 2026-08-01Psilocybin-Assisted Psychotherapy for Treatment-Resistant Depression: A Randomized Phase II Clinical Trial Comparing One Versus Two Psychedelic Doses of Psilocybin (PSI-1V2)ClinicalTrials.gov · 2026-07-09CSF galanin and noradrenaline downregulation by psilocybin therapy in major depressive disorderNeuropsychopharmacology · 2026-07-07Cardiovascular effects associated with acute recreational drug toxicity presentations to the emergency department: a European drug emergencies network (Euro-DEN plus) study.Clinical toxicology (Philadelphia, Pa.) · 2026-06-23Mapping cognitive-behavioral approach in psychedelic-assisted treatment: a systematic review across phases with classic and non-classic psychedelics.European archives of psychiatry and clinical neuroscience · 2026-06-01Global increases in brain glucose metabolism following acute N,N-dimethyltryptamine and harmine administration in healthy volunteers: A randomised [F]FDG-PET study.Journal of cerebral blood flow and metabolism: official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026-06-01Retail Availability of Intoxicating Cannabis and Mushroom Products Across Eleven U.S. Cities: Sales Persist Despite Prohibitions.Journal of studies on alcohol and drugs · 2026-05-28Psilocybin-facilitated Treatment for Cocaine UseClinicalTrials.gov · 2026-05-18Safety and Feasibility of Psilocybin in Methamphetamine Use Disorder in a Community-Based SampleClinicalTrials.gov · 2026-05-12The Music for Subanesthetic Infusions of Ketamine randomised clinical trial: ketamine as a psychedelic treatment for highly refractory depression.The British journal of psychiatry: the journal of mental science · 2026-05-01Acute Cardiovascular Effects of Psilocybin: A Pooled Analysis of 14 Studies with Safety RecommendationsmedRxiv · 2026-04-30Lysergic Acid Diethylamide (LSD) in Palliative Care: a Randomised, Double-blind, Active-placebo Controlled Phase II Study (LPC-Study)ClinicalTrials.gov · 2026-04-29The Ecstasy of Gold in Neurodiversity: Focus on the Use of Psychedelics in Autism Spectrum DisorderPreprints.org · 2026-04-29A128-Channel Wireless Wearable Myolink (W2 Myolink): Functional Characteristics and Multidisciplinary ExperimentsResearch Square · 2026-04-28Psilocybin-Enhanced Psychotherapy for Methamphetamine Use DisorderClinicalTrials.gov · 2026-04-22The QUANTUM Trip Trial - Psilocybin-assisted Therapy for Reducing Alcohol Intake in Patients With Alcohol Use Disorder: A Randomized, Double-blinded, Placebo-controlled Clinical Trial.ClinicalTrials.gov · 2026-03-24Behavioural investigations of psilocybin in non-human animals 1962-2021: A scoping reviewJournal of Psychedelic Studies · 2026-03-09Examining the Safety and Clinical Efficacy of Psilocybin Therapy for Veterans With PTSD: An Open-Label Proof-of-Concept TrialClinicalTrials.gov · 2026-03-04Psilocybin-assisted therapy for demoralisation in hospice patients: feasibility, safety and preliminary efficacy.BMJ supportive & palliative care · 2026-02-27Management of obsessive-compulsive disorder in adults.BMJ (Clinical research ed.) · 2026-02-16Safety and Psychological Effects of Psilocybin and D-Serine Formulation in Healthy VolunteersClinicalTrials.gov · 2026-02-05Patient perspectives on research gaps in cluster headache.Headache · 2026-02-01The therapeutic efficacy of psilocybin in major depressive disorder: A review of recent clinical and mechanistic evidenceZenodo (CERN European Organization for Nuclear Research) · 2026-01-26Daily Administration of Psilocin Mucate (L-130) Produces a Favorable Safety Profile and Anxiolytic Effects in Rodents Exposed to Chronic Unpredictable Mild StressJournal of Psychoactive Drugs · 2026-01-02Building standards of psychedelic care: Qualitative examination of expert perspectives on safety, inclusion, and accountability.The International journal on drug policy · 2026-01-01A novel psychedelic 5-HT receptor agonist GM-2505: The pharmacokinetic, safety, and pharmacodynamic profile from a randomized trial healthy volunteer.Journal of psychopharmacology (Oxford, England) · 2026-01-01An exploration of the relationships between the effects of psilocybin on behavior, 5-HT receptor occupancy, and neuroplastic effects in mice.Journal of psychopharmacology (Oxford, England) · 2026-01-01Marketing by online tobacco retailers: An observational cross-sectional study.Tobacco induced diseases · 2026-01-01Psilocybin as a Serotonergic Therapy in Epilepsy: Narrative Review of Therapeutic Potentials and Seizure RisksAuthorea Preprints · 2025-12-29The CAnadian Network for Psychedelic-Assisted Cancer Therapy (CAN-PACT): A Multi-Phase Program Overview.Current oncology (Toronto, Ont.) · 2025-12-22Standardized Natural Psilocybin-assisted Psychotherapy for Tapering of Opioid Medication in Patients With Chronic Pain: an Open-label Feasibility StudyClinicalTrials.gov · 2025-12-04Sex-specific role of the 5-HT receptor in psilocybin-induced extinction of opioid reward.Nature communications · 2025-11-20CNSC-36. PSILOCYBIN INDUCES SUSTAINED GLIOMA GROWTH THROUGH SEROTONERGIC AND TRKB PATHWAYSNeuro-Oncology · 2025-11-01Psychedelics and ketamine/esketamine in depressive disorders: biological mechanisms and associated neuroimaging and clinical changes.Translational psychiatry · 2025-10-31Visual Hallucinations in Serotonergic Psychedelics and Lewy Body Diseases.Schizophrenia bulletin · 2025-10-06Neurobiological and Therapeutic Potential of Psilocybin in Psychiatric DisordersJournal of Pharma Insights and Research. · 2025-10-05Retrospective Observational Study of Intensity Effects in Psychedelic-assisted TreatmentClinicalTrials.gov · 2025-10-02Differential effects of psilocybin and lisuride on serotonin and dopamine neuronal activity and behavior.Progress in neuro-psychopharmacology & biological psychiatry · 2025-10-02Endocannabinoids, depression, and treatment resistance: Perspectives on effective therapeutic interventions.Psychiatry research · 2025-10-01Therapeutic Effects of Psychedelics and their Non-Hallucinogenic Analogs on Depressive-Like BehaviourCarleton undergraduate journal of science. · 2025-09-02Attitudes Toward Psychedelic-Assisted Therapies for Cancer-Related Psychosocial Symptoms: A Multi- Stakeholder AnalysisResearch Square · 2025-08-19Psilocybin triggers an activity-dependent rewiring of large-scale cortical networksbioRxiv · 2025-08-06363. DIFFERENTIAL EFFECTS OF PSILOCYBIN AND LISURIDE ON SEROTONIN AND DOPAMINE NEURONAL ACTIVITY AND BEHAVIORThe international journal of neuropsychopharmacology · 2025-08-01Psilocybin as Transformative Fast-Acting Antidepressant: Pharmacological Properties and Molecular Mechanisms.Fundamental & clinical pharmacology · 2025-08-01Global Increases in Brain Glucose Metabolism Following Acute N,N-Dimethyltryptamine and Harmine Administration in Healthy Volunteers: An [¹⁸F]FDG-PET StudyResearch Square · 2025-07-27"I've learned that I'm open-minded to this possibility": A qualitative study to evaluate the acceptability of a psilocybin-aided smoking cessation treatment for people with HIV who smoke.Addiction science & clinical practice · 2025-07-21Visual Hallucinations in Serotonergic Psychedelics and Lewy Body DiseasesPsyArXiv · 2025-07-15Visual Hallucinations in Serotonergic Psychedelics and Lewy Body DiseasesPsyArXiv · 2025-07-15The Emerging Use of Psilocybin in Adult Populations with Alcohol Use Disorder: A Scoping ReviewPreprints.org · 2025-06-19Characterization and Identification of an Antimicrobial Compound Psilocybin from Psychedelic Mushroom.Indian journal of microbiology · 2025-06-01Identifying Three Psilocybin Use Patterns by Frequency and Quantity.Journal of studies on alcohol and drugs · 2025-05-01Anaesthetic implications of psilocybin and lysergic acid diethylamide: what is old is now new: A narrative review on psychedelics and anaesthesia.European journal of anaesthesiology · 2025-05-01IUPHAR Article: Psilocybin induces long-lasting effects via 5-HT receptors in mouse models of chronic pain.Pharmacological research · 2025-05-01Visual Hallucinations in Serotonergic Psychedelics and Lewy Body DiseasesPsyArXiv · 2025-03-29Psilocybin in Alcohol Use Disorder With Comorbid DepressionClinicalTrials.gov · 2025-03-19Visual Hallucinations in Serotonergic Psychedelics and Lewy Body DiseasesPsyArXiv · 2025-02-13Exploring the Potential of Psychedelics in the Treatment of Headache Disorders: Clinical Considerations and Exploratory Insights.Current pain and headache reports · 2025-01-16Quality of reporting on psychological interventions in psychedelic treatments: a systematic review.The lancet. Psychiatry · 2025-01-01Roadmap for Equitable Access and Responsible Use of Psilocybin-Assisted Psychotherapy in Palliative Care.Palliative medicine reports · 2025-01-01Psychedelic Research for Alcohol Use Disorder with Comorbid Major Depressive Disorder: An Unmet Need.Current psychiatry reports · 2024-12-01The revival of psilocybin between scientific excitement, evidence of efficacy, and real-world challenges.CNS spectrums · 2024-12-01Meta-correlation of the effect of ketamine and psilocybin induced subjective effects on therapeutic outcome.Npj mental health research · 2024-10-06Psilocybin for Treatment of Alcohol Use Disorder: a Feasibility StudyClinicalTrials.gov · 2024-07-12Psilocybin for dementia prevention? The potential role of psilocybin to alter mechanisms associated with major depression and neurodegenerative diseases.Pharmacology & therapeutics · 2024-06-01Psilocybin for dementia prevention? The potential role of psilocybin to alter mechanisms associated with major depression and neurodegenerative diseasesPharmacology & therapeutics · 2024-06-01Impact of Psilocybin on Peripheral Cytokine Production.Psychedelic medicine (New Rochelle, N.Y.) · 2024-06-01The Classical Psychedelic Psilocybin Mitigates Oxycodone WithdrawalJournal of Pharmacology and Experimental Therapeutics · 2024-05-13Author Correction: Psilocybin enhances insightfulness in meditation: a perspective on the global topology of brain imaging during meditation.Scientific reports · 2024-04-23Pharmacology of Classical Psychedelic in Mouse Models of Chronic PainJournal of Pain · 2024-03-31Psilocybin enhances insightfulness in meditation: a perspective on the global topology of brain imaging during meditation.Scientific reports · 2024-03-26Effects of psilocybin and sleep quality on brain water diffusivity and microstructure in healthy individuals and chronic cluster headache patientsNeuroscience Applied · 2024-01-01Potential Benefits of Psilocybin for Lupus Pain: A Case Report.Current rheumatology reviews · 2024-01-01Serotoninergic antidepressants combination in psilocybin-assisted psychotherapy: a case report.Frontiers in psychiatry · 2024-01-01Psychedelics and cognitive function: A systematic reviewResearch Society and Development · 2023-12-13Peer support and psychedelics.Journal of military, veteran and family health · 2023-12-01[Feeling unwell after eating a piece of chocolate].Nederlands tijdschrift voor geneeskunde · 2023-11-23An open-label pilot trial assessing tolerability and feasibility of LSD microdosing in patients with major depressive disorder (LSDDEP1).Pilot and feasibility studies · 2023-10-05Psilocybin-Assisted Therapy: A scoping review of participants’ and facilitators’ experiences in qualitative studiesResearch, Society and Development · 2023-09-22P05-02: Assessment of the CYP450 inhibitory activity of psilocybin, psilocin, LSD, 5-MeO-DMT and mescaline: An in vitro studyToxicology Letters · 2023-09-01Psilocybin intoxication did not affect daytime or sleep-related declarative memory consolidation in a small sample exploratory analysis.European neuropsychopharmacology: the journal of the European College of Neuropsychopharmacology · 2023-09-01Clinical specificity profile for novel rapid acting antidepressant drugs.International clinical psychopharmacology · 2023-09-01Imprinting: expanding the extra-pharmacological model of psychedelic drug action to incorporate delayed influences of sets and settingsFrontiers in Human Neuroscience · 2023-07-17Evaluating the Effect of Length of Time on Selective Serotonin Reuptake Inhibitors (SSRIs) on the Response to Psilocybin-assisted Therapy in Individuals With Mild-moderate Major Depressive Disorder (MDD)ClinicalTrials.gov · 2023-07-06Novel psilocin prodrugs with altered pharmacological properties as candidate therapies for treatment-resistant anxiety disordersbioRxiv · 2023-05-18The Safety and Efficacy of Psilocybin in Participants With Treatment Resistant DepressionClinicalTrials.gov · 2023-04-24High-resolution tracking of unconfined zebrafish behavior reveals stimulatory and anxiolytic effects of psilocybinbioRxiv · 2023-04-14Mood and Cognitive Effects of Low Doses of Psilocybin Observed in Healthy Subjects ("MELO"): A Blinded, Placebo-Controlled, Dose-Finding StudyClinicalTrials.gov · 2023-03-20A systematic literature review and meta-analysis of the effect of psilocybin and methylenedioxymethamphetamine on mental, behavioural or developmental disorders.The Australian and New Zealand journal of psychiatry · 2023-03-01Psychedelic-Induced Serotonin 2A Receptor Downregulation Does Not Predict Swim Stress Coping in Mice.International journal of molecular sciences · 2022-12-04Policy considerations that support equitable access to responsible, accountable, safe, and ethical uses of psychedelic medicines.Neuropharmacology · 2022-11-15Towards psychedelic apprenticeship: Developing a gentle touch for the mediation and validation of psychedelic-induced insights and revelations.Transcultural psychiatry · 2022-10-01Culture, context, and ethics in the therapeutic use of hallucinogens: Psychedelics as active super-placebos?Transcultural psychiatry · 2022-10-01Psilocybin Therapy for Treatment Resistant Depression: Prediction of Clinical Outcome by Natural Language ProcessingPsyArXiv · 2022-09-30Multicentre Study To Assess Safety And Efficacy Of Psilocybin In Patients With Treatment-Resistant Depression Following Completion Of COMP 001 And COMP 003 Trials (P-TRD LTFU)ClinicalTrials.gov · 2022-09-22Molecular Structure, Reactivity and Spectroscopic Properties of Hallucinogens Psilocybin, Mescaline and their Derivatives - A Computational StudyLetters in Applied NanoBioScience · 2022-09-17P03-18 Simultaneous detection and quantification of psilocybin and psilocin by gas chromatography coupled to mass spectrometry (GC-MS)Toxicology Letters · 2022-09-01Dark Side of the Shroom: Erasing Indigenous and Counterculture Wisdoms with Psychedelic Capitalism, and the Open Source AlternativeAnthropology of Consciousness · 2022-08-22Randomized Double Blind Placebo Controlled Assessing the Efficacy of Micro-dosed Psilocybin in Reducing Anxiety and or Depression Levels in AdultsClinicalTrials.gov · 2022-06-30Psilocybin-Mediated Attenuation of Gamma Band Auditory Steady-State Responses (ASSR) Is Driven by the Intensity of Cognitive and Emotional Domains of Psychedelic Experience.Journal of personalized medicine · 2022-06-19New Paradigms of Old Psychedelics in Schizophrenia.Pharmaceuticals (Basel, Switzerland) · 2022-05-23Selling the Priceless Mushroom: A History of Psilocybin Mushroom Trade in the Sierra Mazateca (Oaxaca)Journal of Illicit Economies and Development · 2022-01-01Psychedelics and health behaviour change.Journal of psychopharmacology (Oxford, England) · 2022-01-01Psychedelic medicines for mood disorders: current evidence and clinical considerations.Current opinion in psychiatry · 2022-01-01Virtual Reality as a Moderator of Psychedelic-Assisted Psychotherapy.Frontiers in psychology · 2022-01-01Medicinal psychedelics for mental health and addiction: Advancing research of an emerging paradigm.The Australian and New Zealand journal of psychiatry · 2021-12-01Psilocybin therapy increases cognitive and neural flexibility in patients with major depressive disorder.Translational psychiatry · 2021-11-08Magic mushroom: all is not as it seems.Acta chirurgica Belgica · 2021-09-30Use of alternative therapy with Psilocybin in oncologic patients with depression and/or anxiety disorders - integrative reviewResearch Society and Development · 2021-08-19Molecular and Functional Imaging Studies of Psychedelic Drug Action in Animals and Humans.Molecules (Basel, Switzerland) · 2021-04-22Evaluating the Risk of Psilocybin for the Treatment of Bipolar Depression: A Review of the Research Literature and Published Case StudiesmedRxiv · 2021-04-07Psychedelics and Health Behavior Change - Journal of Psychopharmacology (in press)PsyArXiv · 2021-03-24Hallucinogens in Mental Health: Preclinical and Clinical Studies on LSD, Psilocybin, MDMA, and Ketamine.The Journal of neuroscience: the official journal of the Society for Neuroscience · 2021-02-03A Single Dose of Psilocybin Increases Synaptic Density and Decreases 5-HT Receptor Density in the Pig Brain.International journal of molecular sciences · 2021-01-15Effects of a single dose of psilocybin on behaviour, brain 5-HT receptor occupancy and gene expression in the pig.European neuropsychopharmacology: the journal of the European College of Neuropsychopharmacology · 2021-01-01Psychedelics in Psychiatry: Neuroplastic, Immunomodulatory, and Neurotransmitter Mechanisms.Pharmacological reviews · 2021-01-01Evaluating the Potential Use of Serotonergic Psychedelics in Autism Spectrum Disorder.Frontiers in pharmacology · 2021-01-01P.804A single dose of psilocybin increases synaptic density and decreases 5-HT2A receptor density in the pig brainEuropean Neuropsychopharmacology · 2020-11-01The Role of Psychedelics and Counseling in Mental Health TreatmentJournal of Mental Health Counseling · 2020-10-01S-Adenosyl-l-Methionine Salvage Impacts Psilocybin Formation in "Magic" Mushrooms.Chembiochem: a European journal of chemical biology · 2020-05-04[Addictions].Revue medicale suisse · 2020-01-15The Effects of Daytime Psilocybin Administration on Sleep: Implications for Antidepressant Action.Frontiers in pharmacology · 2020-01-01Management of Treatment-Resistant Depression: Challenges and Strategies.Neuropsychiatric disease and treatment · 2020-01-01The Past and Future of Psychedelic Science: An Introduction to This Issue.Journal of psychoactive drugs · 2019-01-01Psilocybin disrupts sensory and higher order cognitive processing but not pre-attentive cognitive processing-study on P300 and mismatch negativity in healthy volunteers.Psychopharmacology · 2018-02-01d-Lysergic acid diethylamide, psilocybin, and other classic hallucinogens: Mechanism of action and potential therapeutic applications in mood disorders.Progress in brain research · 2018-01-01The "Endless Trip" among the NPS Users: Psychopathology and Psychopharmacology in the Hallucinogen-Persisting Perception Disorder. A Systematic Review.Frontiers in psychiatry · 2017-01-0114C-Psilocin tissue distribution in pregnant rats after intravenous administrationFunctional Foods in Health and Disease · 2014-07-27Glucuronidation of Psilocin and 4-Hydroxyindole by the Human UDP-GlucuronosyltransferasesDrug Metabolism and Disposition · 2010-03-01Personality Characteristics of Adolescents with Hallucinogen, Methamphetamine, and Cannabis Dependence: A Comparative StudyJournal of Child & Adolescent Substance Abuse · 2005-12-05Electrocardiographic examination of heart function in rats exposed to hallucinogens from Psilocybe mushroomsActa Toxicologica · 2003-01-01Patterns of recreational drug use at dance events in Edinburgh, Scotland.Addiction (Abingdon, England) · 2001-07-01Analysis of psilocybin and psilocin in psilocybe subcubensis Guzman by ion mobility spectrometry and gas chromatography-mass spectrometryJournal of Clinical Forensic Medicine · 1999-09-01Analysis of psilocybin and psilocin in Psilocybe subcubensis GUZMÁN by ion mobility spectrometry and gas chromatography-mass spectrometryForensic Science International · 1999-01-01Application of a radioimmunoassay screening test for detection and management of phencyclidine intoxication.Journal of clinical pharmacology · 1980-01-01[COMPARISON OF PSYCHOPHARMACA LSD-25, BOL-148 AND PSILOCYBIN IN CLINICAL PRACTICE].Vojnosanitetski pregled · 1963-05-01[OUR CLINICAL EXPERIENCE WITH A NEW PHARMACOLOGICAL PREPARATION PSILOCYBIN].Neuropsihijatrija · 1963-01-01