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Mindfulness-Based Psilocybin-Assisted Therapy (MB-PAT) for cancer-related demoralization in Canada: The case for a hybrid group-based delivery modelPsychedelics · 2026-12-01Contribution of the Serotonin 5-HT2A Receptor to the Therapeutic Effect of Psilocin on Social Behavior Deficits in Mice Repeatedly Exposed to Social Defeat StressNeuropsychopharmacology Reports · 2026-09-01Genome-based optimization of psilocybin and N,N-dimethyltryptamine biosynthetic pathways in E. coli using CRISPR-associated transposasesMetabolic Engineering · 2026-09-01Psilocybin-assisted psychotherapy for substance use disorders as a complex intervention: A systematic review of efficacy, mechanisms and psychotherapeutic frameworksJournal of Psychopharmacology · 2026-08-17Exploring the In Vitro Effect of Psilocybin on the Composition and Metabolic Activity of Gut Microbiota in Individuals with Severe AnxietyDrugs and Drug Candidates · 2026-08-12Psilocybin-Assisted Therapy in Psychiatry: A Narrative Clinical Review of Mechanisms, Therapeutic Applications, and Emerging Evidence (2025-2026)Journal of Clinical Medicine · 2026-08-12A Phase III, Multicentre, Randomised, Double-blind, Controlled Study to Investigate the Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in Participants With Treatment-resistant DepressionClinicalTrials.gov · 2026-08-10Long- term administration of low doses of psilocybin causes epigenetic changes in the rat medial prefrontal cortexPsychopharmacology · 2026-07-28Longitudinal neural and psychological changes following psilocybin under compassion imagery primingFrontiers in Human Neuroscience · 2026-07-22Psilocybin produces amplified acute responses and sex-specific long-term increases in sensorimotor gating in the mGlu5 knockout mouse model of schizophreniaNeuropsychopharmacology · 2026-07-18Psilocybin's effect on human brain synaptic plasticity.Translational psychiatry · 2026-07-15α2-Adrenergic receptor modulates 5-HT2A-mediated behavioral effects of MDMA and psilocybin in miceMolecular Psychiatry · 2026-07-07CSF galanin and noradrenaline downregulation by psilocybin therapy in major depressive disorderNeuropsychopharmacology · 2026-07-07Naturally Derived Psilocybin for Therapeutic Use: A Six-Criterion Framework for Evidence, Safety, and Benefit-Risk Considerations in Policy and Clinical DevelopmentBiomolecules · 2026-07-03Psilocybin as a Transdiagnostic Treatment for Eating Disorders and Comorbid Psychopathology: Implications for Clinical Nosology and Research DirectionsInternational Journal of Eating Disorders · 2026-07-02Past-Year Psilocybin and Alcohol Co-Use: Associations With Mental Health SymptomsJournal of Drug Issues · 2026-07-01Modeled Long-Term Effects of Psilocybin on Dynamic Activity and Effective Connectivity of Fronto-Striatal-Thalamic CircuitsHuman Brain Mapping · 2026-07-01Revealing shortcomings in the assessment of psilocybin effects on OCD-related symptoms in preclinical and clinical studies: A systematic reviewJournal of Affective Disorders Reports · 2026-07-01Psilocybin restores behavior and 5-HT2A signaling while reducing microglial density after chronic traumatic brain injury in ratsCell Reports Medicine · 2026-07-01The relevance of the 5HT2A-mGlu2 heterodimer in explaining the clinical ambivalence of psilocybinRevista de Neuro-Psiquiatría · 2026-06-30Study Protocol for “Exploring the safety and therapeutic potential of psilocybin in the treatment of anorexia nervosa in adolescents and young adults”PLOS One · 2026-06-30Chemical ecology and convergent evolution of natural hallucinogens: From ecological defense to conserved neural targets.Proceedings of the National Academy of Sciences of the United States of America · 2026-06-30DESI-MSI-Based Multi-Organ Distribution Mapping of Psilocin in ZebrafishMolecules · 2026-06-18Community engagement as a foundation for implementation research for group psilocybin assisted therapy in New MexicoFrontiers in Public Health · 2026-06-17Psychedelics disrupt hierarchical cortical propagations in the default mode network of humans and mice.Proceedings of the National Academy of Sciences of the United States of America · 2026-06-16Psilocybin and Mental Health Outcomes: Scoping Review with ☸️SAIMSARASAIMSARA Journal · 2026-06-15Psilocybin: Chemical Foundations and Emerging Therapeutic PotentialMini-Reviews in Medicinal Chemistry · 2026-06-01Sex-dependent developmental changes in behavior, brain structure, functional connectivity, and sensory perception following exposure to psilocybin during adolescence.Neuropsychopharmacology: official publication of the American College of Neuropsychopharmacology · 2026-06-01Psilocybin Decreases Preference for Large Rewards Accompanied by Increased Activity of Parvalbumin Neurons With Perineuronal Nets in the Medial Prefrontal CortexEuropean Journal of Neuroscience · 2026-06-01Therapeutic advances in fibromyalgia: one year in review 2026.Clinical and experimental rheumatology · 2026-06-01Examining the effects of psilocybin-assisted psychotherapy on anhedonia in treatment-resistant depressionJournal of Affective Disorders · 2026-06-01Effects of psilocybin on sleep quality and brain microstructure in chronic cluster headacheJournal of Psychopharmacology · 2026-05-29Psychedelic-induced hypomania and mania: a systematic review and meta-analysis.Molecular psychiatry · 2026-05-29Transient multidomain functional improvement in advanced Alzheimer’s disease following high-dose psilocybin-containing mushroom administration: a case reportFrontiers in Neuroscience · 2026-05-28Mescaline Alters Cerebellar Function, Global Connectivity, and Frequency-Selective Acoustic Gating: A BOLD fMRI Study in Awake Rats.Neuroscience bulletin · 2026-05-21Human brain changes after first psilocybin useNature Communications · 2026-05-05Psilocin mediates long-term synaptic depression in the prelimbic cortex through 5-HT2A receptor-independent mechanismsNeuropharmacology · 2026-05-01Advancing cancer neuroscience through stress modulation: Interdisciplinary potential of psilocybin and ketamineGeneral Hospital Psychiatry · 2026-05-01Psilocybin ameliorates neuropathic pain-like behaviour in mice and facilitates gabapentin-mediated analgesiaCommunications Biology · 2026-04-24The efficacy and safety of psilocybin-assisted therapy for major depressive disorder: a meta-analytic review of clinical outcomesMental Wellness · 2026-04-21Efficacy and Safety of Psilocybin-Assisted Therapy for Depression: A Meta-Analysis of Randomised Controlled TrialsOpen Access Indonesian Journal of Medical Reviews · 2026-04-21Effects of a single dose of psilocybin on diet-induced weight loss in obese miceTranslational Psychiatry · 2026-04-14Psilocybin for Treatment of Prolonged Grief Disorder: An Open-Label Feasibility Study ProtocolPsychoactives · 2026-04-13Observing the mind under psychedelics: conceptual metaphors used following four once-weekly macrodoses of psilocybinPhilosophical Psychology · 2026-04-10Psilocybin elicits a conserved glucocorticoid-responsive gene signature across five 5-HT2A receptor-rich brain regions in rat.Acta neuropsychiatrica · 2026-04-10Sex-specific increased reactivity of the PVT and prolonged PVT→CeA circuit engagement following psilocin administrationNature Communications · 2026-04-10Serotonergic modulation of cortical gamma synchronization: right-lateralized psilocin effects on 40 Hz auditory steady-state responses in ratsJournal of Neurophysiology · 2026-04-01Psilocin fosters neuroplasticity in iPSC-derived human cortical neuronseLife · 2026-03-27Psilocybin shapes the slow, global propagation of brain activity over the cortical layout of 5HT2a receptorsCommunications Biology · 2026-03-26Psilocybin effects on brain functional connectivity: a systematic review of fMRI studiesDiscover Mental Health · 2026-03-19Behavioural investigations of psilocybin in non-human animals 1962-2021: A scoping reviewJournal of Psychedelic Studies · 2026-03-09“Diversity makes the richness of humanity”: The emergence and persistence of mental imagery after self-reported psilocybin truffles intake in an autistic woman with “blind imagination” (aphantasia): A33-month retrospective case reportJournal of Psychedelic Studies · 2026-03-09Journeying into Right Relations: Scientists Turn to Psilocybin to Shift Psychological Burdens of Global Environmental Change and Find Transformational Pathways ForwardAction Research · 2026-03-01Psilocybin-induced alterations in EEG power, connectivity and network dynamics in healthy subjects: Correlations with subjective experience and implications for therapeutic applicationsProgress in Neuro-Psychopharmacology and Biological Psychiatry · 2026-03-01Calcium activation mechanism of a noncanonical aromatic L-amino acid decarboxylase from psilocybin mushroom Psilocybe cubensisCommunications Biology · 2026-02-26Acute psilocin increased cortical activity in ratFrontiers in Neuroscience · 2026-02-04Approved and Pipeline Pharmacological Interventions for Eating Disorders (2010-2025): 15 Years of Progress (or Lack Thereof).CNS drugs · 2026-02-01The effect of psilocin on neurotransmitters release in the claustrum and on rat behaviorPharmacological Reports · 2026-02-01Behavioral effects of psychedelic and non-psychedelic serotonin 2A receptor agonist drugs in pigsNeuroscience Applied · 2026-01-01A Systematic Review of the efficacy, safety, and Tolerability of Psychedelics in the Treatment of post-traumatic Stress DisorderCurrent Treatment Options in Psychiatry · 2025-12-25Effects of LSD and Psilocybin on Heart Rate in Patients Receiving Psychedelic Treatment for Depressive and Anxiety Disorders: A Retrospective Observational StudyPsychology International · 2025-12-19The Psychedelic Psilocin Suppresses Activity of Central Amygdala Corticotropin-Releasing Factor Receptor 1 Neurons and Decreases Ethanol Drinking in Female MiceThe Journal of Neuroscience · 2025-12-10Zalsupindole is a Nondissociative, Nonhallucinogenic Neuroplastogen with Therapeutic Effects Comparable to Ketamine and Psychedelics.ACS chemical neuroscience · 2025-11-19Psychedelics in the Treatment of Neurologic and Psychiatric Disorders: Coincidence or a New Point of View.Molecular neurobiology · 2025-11-01Differential effects of psilocybin and lisuride on serotonin and dopamine neuronal activity and behavior.Progress in neuro-psychopharmacology & biological psychiatry · 2025-10-02Evolution and Comparative Analysis of Clinical Trials on Psilocybin in the Treatment of Psychopathologies: Trends in the EU and the US.Journal of clinical medicine · 2025-09-19Cross-Species Evidence for Psilocin-Induced Visual Distortions: Apparent Motion Is Perceived by Both Humans and RatsBiological Psychiatry Global Open Science · 2025-09-01The Medial Prefrontal Cortex Modulates Psychedelic-like Effects of PsilocinACS Pharmacology & Translational Science · 2025-08-08363. DIFFERENTIAL EFFECTS OF PSILOCYBIN AND LISURIDE ON SEROTONIN AND DOPAMINE NEURONAL ACTIVITY AND BEHAVIORThe international journal of neuropsychopharmacology · 2025-08-01Overview and Specificity of Psilocybin Use in the Treatment of Mental Disorders:.Psychedelic medicine (New Rochelle, N.Y.) · 2025-08-01Psychedelic use in individuals living with eating disorders or disordered eating: findings from the international MED-FED survey.Journal of eating disorders · 2025-07-24Exploring Jordanian Physicians' and Medical Students' Perspectives on Ketamine and Psychedelic-Assisted Therapies: An Insight from the Middle East.Journal of psychoactive drugs · 2025-07-06Psilocybin Modulates TPJ Effective Connectivity during Out-of-Body ExperiencesmedRxiv · 2025-06-25Role of endogenous serotonin in psychedelic-like effects of psilocybin in mice.The international journal of neuropsychopharmacology · 2025-06-06Characterization and Identification of an Antimicrobial Compound Psilocybin from Psychedelic Mushroom.Indian journal of microbiology · 2025-06-01Psilocybin and psilocin regulate microglial immunomodulation and support neuroplasticity via serotonergic and AhR signalingInternational Immunopharmacology · 2025-06-01Extraction Yields of Psilocybin and Psilocin: A Short Review of Current Methods and Their ImplicationsPharmaceuticals · 2025-03-07Molecular insights into the modulation of the 5 HT2 A receptor by serotonin, psilocin, and the G protein subunit GqαFEBS Letters · 2025-03-01Setting the Stage for the Inner Journey: Unraveling the Interplay of Contextual Factors and the Intensity of Psychedelic-Induced Ego Dissolution.Journal of psychoactive drugs · 2025-02-13Dose-dependent changes in global brain activity and functional connectivity following exposure to psilocybin: a BOLD MRI study in awake ratsbioRxiv · 2025-02-06ANXIOLYTIC- AND PROCOGNITIVE-LIKE EFFECTS OF A30-DAY CHRONIC TREATMENT WITH A LOW NON-PSYCHEDELIC DOSE OF PSILOCYBIN IN C57BL/6J MICEThe international journal of neuropsychopharmacology · 2025-02-01Uncovering Psychedelics: From Neural Circuits to Therapeutic Applications.Pharmaceuticals (Basel, Switzerland) · 2025-01-19Novel psychedelic interventions for post-traumatic stress disorder and their promise for precision medicine.Therapeutic advances in psychopharmacology · 2025-01-01Psychedelic-Assisted Therapy: The Emerging Role of the Psychiatric-Mental Health NurseSaudi Journal of Medicine and Public Health · 2024-12-31Psilocybin Fungi Unveiled: Morphological Characteristics and Pharmacological PotentialsInternational Journal for Research in Applied Science and Engineering Technology · 2024-11-17Preliminary safety and effectiveness of psilocybin-assisted therapy in adults with fibromyalgia: An open-label, pilot clinical trialPsyArXiv · 2024-11-04Meditating on psychedelics. A randomized placebo-controlled study of DMT and harmine in a mindfulness retreat.Journal of psychopharmacology (Oxford, England) · 2024-10-01Addressing a major interference in the quantification of psilocin in mouse plasma: Development of a validated liquid chromatography tandem mass spectrometry methodJournal of Chromatography A · 2024-08-01Effects of psilocin and psilocybin on human 5-HT4 serotonin receptors in atrial preparations of transgenic mice and humansToxicology Letters · 2024-07-01Historical Perspectives and Pharmacodynamic Actions of the Magic Mushroom (Psilocybin) for Future Global HealthcareTrends in Medical Research · 2024-06-28Psilocybe cubensis extract potently prevents fear memory recall and freezing behavior in short- but not long-term in a rat model of posttraumatic stress disorder.Behavioral neuroscience · 2024-04-01Prefrontal Electrophysiological Biomarkers and Mechanism-Based Drug Effects in a Rat Model of Alcohol AddictionResearch Square · 2024-02-22Psychedelics: The New Kid on the BlockAnnals of Indian Psychiatry · 2024-01-01Psychedelic Therapy: A Primer for Primary Care Clinicians-Historical Perspective and Overview.American journal of therapeutics · 2024-01-01Psychedelic Therapy: A Primer for Primary Care Clinicians-Psilocybin.American journal of therapeutics · 2024-01-01Psychedelic Therapy: A Primer for Primary Care Clinicians - Part I. Historical Perspective and OverviewPsyArXiv · 2023-12-26Psychedelic Therapy: A Primer for Primary Care Clinicians - Part IV. PsilocybinPsyArXiv · 2023-12-26Psychedelic Therapy: A Primer for Primary Care Clinicians - Part I. Historical Perspective and OverviewPsyArXiv · 2023-12-26Psychedelic Therapy: A Primer for Primary Care Clinicians - Part IV. PsilocybinPsyArXiv · 2023-12-26Investigation of the structure, stability, and relative solubility of psilocybin in water and pure organic solvents: A molecular simulation studyJournal of Molecular Liquids · 2023-11-07Addressing the Current Knowledge and Gaps in Research Surrounding Lysergic Acid Diethylamide (LSD), Psilocybin, and Psilocin in Rodent ModelsCurrent Topics in Medicinal Chemistry · 2023-09-01Underlying pharmacological mechanisms of psilocin-induced broadband desynchronization and disconnection of EEG in ratsFrontiers in Neuroscience · 2023-06-22Psilocin suppresses methamphetamine-induced hyperlocomotion and acquisition of conditioned place preference via D2R-mediated ERK signalingCNS Neuroscience & Therapeutics · 2023-03-01Conformational Landscape and Hydrogen Bonding Pattern of Psilocin: Computational InsightsChemistrySelect · 2023-01-09Behavioral effects of a 14-day repeated treatment with psilocybin at a low non-psychedelic dose: a preliminary study in C57BL/6J miceNeuroscience Applied · 2023-01-01Visualizing drug actions on dendrites: psilocybin and other classic psychedelicsBiophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN) · 2023-01-01Use of Selective Alternative Therapies for Treatment of OCD.Neuropsychiatric disease and treatment · 2023-01-01Safety, tolerability, and clinical and neural effects of single-dose psilocybin in obsessive-compulsive disorder: protocol for a randomized, double-blind, placebo-controlled, non-crossover trial.Frontiers in psychiatry · 2023-01-01Safety, feasibility, tolerability, and clinical effects of repeated psilocybin dosing combined with non-directive support in the treatment of obsessive-compulsive disorder: protocol for a randomized, waitlist-controlled trial with blinded ratings.Frontiers in psychiatry · 2023-01-01Psilocybin modulation of time-varying functional connectivity is associated with plasma psilocin and subjective effectsNeuroImage · 2022-12-01Mode of action of psilocybinMedicom Conference Report ECNP 2022 · 2022-11-28A Research Domain Criteria (RDoC)-Guided Dashboard to Review Psilocybin Target Domains: A Systematic Review.CNS drugs · 2022-10-01From neuroplasticity to psychoplasticity: Psilocybin may reverse personality disorders and political fanaticismCurrent Psychiatry · 2022-09-01Development of an -based norbaeocystin production platform and evaluation of behavioral effects in rats.Metabolic engineering communications · 2022-06-01Psilocin acutely alters sleep-wake architecture and cortical brain activity in laboratory miceTranslational Psychiatry · 2022-02-23Unravelling a New Conformer of Psilocin Through Computational MethodsSSRN Electronic Journal · 2022-01-01A Complex Impact of Systemically Administered 5-HT2A Receptor Ligands on Conditioned Fear.The international journal of neuropsychopharmacology · 2021-09-21Psilocybin-induced changes in brain network integrity and segregation correlate with plasma psilocin level and psychedelic experienceEuropean Neuropsychopharmacology · 2021-09-01Harnessing psilocybin: antidepressant-like behavioral and synaptic actions of psilocybin are independent of 5-HT2R activation in mice.Proceedings of the National Academy of Sciences of the United States of America · 2021-04-27Therapeutic Potential of Psychedelics in Treatment of Psychiatric Disorders, Part 2The Journal of Clinical Psychiatry · 2021-02-23POTENCIAL USO DA PSILOCIBINA NO TRATAMENTO DA DEPRESSÃO: UMA REVISÃO / POTENTIAL USE OF PSILOCYBIN IN THE DEPRESSION TREATMENT: A REVIEWBrazilian Journal of Development · 2021-01-01Evaluating the Potential Use of Serotonergic Psychedelics in Autism Spectrum Disorder.Frontiers in pharmacology · 2021-01-01Trip Reports: Exploring the Experience of Psychedelic IntoxicationLund University Publications (Lund University) · 2020-12-31The emerging role of psilocybin and MDMA in the treatment of mental illness.Expert review of neurotherapeutics · 2020-12-01Nothing Ventured, Nothing Gained: Regulations Cripple Potentially Life-Saving Research of Illicit Substances.ACS chemical neuroscience · 2020-05-20Dynamic coupling of whole-brain neuronal and neurotransmitter systems.Proceedings of the National Academy of Sciences of the United States of America · 2020-04-28Transformative experience and social connectedness mediate the mood-enhancing effects of psychedelic use in naturalistic settings.Proceedings of the National Academy of Sciences of the United States of America · 2020-02-04Enzymatic Route toward 6-Methylated Baeocystin and Psilocybin.Chembiochem: a European journal of chemical biology · 2019-11-18Injury-Triggered Blueing Reactions of Psilocybe “Magic” MushroomsAngewandte Chemie · 2019-11-14Psychedelic effects of psilocybin correlate with serotonin 2A receptor occupancy and plasma psilocin levelsNeuropsychopharmacology · 2019-06-01Microdosing psychedelics: personality, mental health, and creativity differences in microdosers.Psychopharmacology · 2019-02-01Production Options for Psilocybin: Making of the Magic.Chemistry (Weinheim an der Bergstrasse, Germany) · 2019-01-18Microdosing Psychedelics: Personality, mental health, and creativity differences in microdosersPsyArXiv · 2018-11-02Mushroom Poisoning Cases in Dogs and Cats: Diagnosis and Treatment of Hepatotoxic, Neurotoxic, Gastroenterotoxic, Nephrotoxic, and Muscarinic Mushrooms.The Veterinary clinics of North America. Small animal practice · 2018-11-01Iterative l-Tryptophan Methylation in Psilocybe Evolved by Subdomain Duplication.Chembiochem: a European journal of chemical biology · 2018-10-18Hallucinogen persisting perception disorder: A literature review and three case reports.Journal of addictive diseases · 2018-01-01Navigating Psychedelic Medicines through (Inter)national RegulationNorthumbria Research Link (Northumbria University) · 2017-07-01The Development and Regulation of Psychedelic MedicinesNorthumbria Research Link (Northumbria University) · 2017-04-05Maddening Therapies: How Hallucinogens Morphed into Novel TreatmentsCurrent psychiatry · 2017-01-01Effects of serotonin 2A/1A receptor stimulation on social exclusion processing.Proceedings of the National Academy of Sciences of the United States of America · 2016-05-03Observations concerning the synthesis of tryptamine homologues and branched tryptamine derivatives via the borrowing hydrogen process: synthesis of psilocin, bufotenin, and serotoninTetrahedron · 2016-05-01Neurovascular and neuroimaging effects of the hallucinogenic serotonin receptor agonist psilocin in the rat brainNeuropharmacology · 2015-12-01Research on Acute Toxicity and the Behavioral Effects of Methanolic Extract from Psilocybin Mushrooms and Psilocin in MiceToxins · 2015-03-27Spatiotemporal brain dynamics of emotional face processing modulations induced by the serotonin 1A/2A receptor agonist psilocybin.Cerebral cortex (New York, N.Y.: 1991) · 2014-12-01Recreational drug discovery: natural products as lead structures for the synthesis of smart drugs.Natural product reports · 2014-07-01The Effect of Psilocin on Memory Acquisition, Retrieval, and Consolidation in the RatFrontiers in Behavioral Neuroscience · 2014-05-16Fungal Hallucinogens Psilocin, Ibotenic Acid, and MuscimolTherapeutic Drug Monitoring · 2013-08-01Neural correlates of the psychedelic state as determined by fMRI studies with psilocybin.Proceedings of the National Academy of Sciences of the United States of America · 2012-02-07Novel, unifying mechanism for mescaline in the central nervous system: electrochemistry, catechol redox metabolite, receptor, cell signaling and structure activity relationships.Oxidative medicine and cellular longevity · 2009-01-01Investigation into the temporal stability of aqueous standard solutions of psilocin and psilocybin using high performance liquid chromatographyScience & Justice · 2006-04-01The Determination of Psilocin and Psilocybin in Hallucinogenic Mushrooms by HPLC Utilizing a Dual Reagent Acidic Potassium Permanganate and Tris(2,2′-bipyridyl)ruthenium(II) Chemiluminescence Detection SystemJournal of Forensic Sciences · 2006-01-01Determination of psilocin and psilocybin using flow injection analysis with acidic potassium permanganate and tris(2,2′-bipyridyl)ruthenium(II) chemiluminescence detection respectivelyTalanta · 2005-08-15Analysis of psilocin in Polish hallucinogenic mushroomsActa Poloniae Toxicologica · 1998-01-01Biosynthesis of psilocybin. II. Incorporation of labelled tryptamine derivatives.Acta chemica Scandinavica · 1968-01-01