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Pupil-DLC: An open-source deep learning pipeline for scalable, marker-less tracking of pupil dynamics across conscious and unconscious states.Journal of neuroscience methods · 2026-11-01MDMA and Psilocybin Regulate Oligodendrocyte-Lineage Cell Numbers and Anxiety-Like Behaviors in a Rat Model of Fear.Biological psychiatry · 2026-09-15Psilocybin-induced changes in electroencephalography link acute and long-term effects.Journal of psychopharmacology (Oxford, England) · 2026-09-04Assessing The Readiness of Psychiatrists in Louisiana to Incorporate Psilocybin into Clinical Practice-Lessons Learned from a State Underrepresented in Clinical Psychedelic Research.Psychedelic medicine (New Rochelle, N.Y.) · 2026-09-01Psilocybin collapses visual change detection and drives cortical dynamics toward a state of surprisebioRxiv · 2026-08-25Distinct response of resting-state brain networks to psilocybin in autismmedRxiv · 2026-08-22A Phase III, Multicentre, Randomised, Double-blind, Controlled Study to Investigate the Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in Participants With Treatment-resistant DepressionClinicalTrials.gov · 2026-08-10Effects of LSD, DMT and psilocybin on cognitive and psychological functions: A systematic review of the literature.Journal of psychopharmacology (Oxford, England) · 2026-08-01Anxiety-related platform in zebrafish (Danio rerio) larvae: An integrated analysis of behavioural and molecular assay in drug screening research.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2026-08-01Mystery shopper assessments of cannabis retailer practices and regulatory compliance in five U.S. states, 2025.Drug and alcohol dependence · 2026-08-01Convergent neuroimmune signaling underlying rapid antidepressant response to ketamine and psychedelics.Molecular psychiatry · 2026-07-28Psilocybin selectively rescues cognitive flexibility impairments caused by aberrant prefrontal error signaling.bioRxiv: the preprint server for biology · 2026-07-09Modeled Long-Term Effects of Psilocybin on Dynamic Activity and Effective Connectivity of Fronto-Striatal-Thalamic CircuitsHuman Brain Mapping · 2026-07-01Psychedelic Use, Microdosing, Motives, and Information and Product Sources Among Young Adults in the United States.Journal of psychoactive drugs · 2026-06-19Psychedelics for treatment of negative symptoms and depressive symptoms in schizophrenia spectrum disorder: A narrative review.Schizophrenia research · 2026-06-01U.S. Psychedelic Use and Microdosing in 2025: Insights from a Probability-Based and Nationally Representative Survey.Rand health quarterly · 2026-06-01Psychological support in psychedelic-assisted therapy clinical trials: A systematic review.Journal of psychopharmacology (Oxford, England) · 2026-05-01A128-Channel Wireless Wearable Myolink (W2 Myolink): Functional Characteristics and Multidisciplinary ExperimentsResearch Square · 2026-04-28Structural plasticity and enhanced fear extinction following psilocybin in chronically stressed mice.bioRxiv: the preprint server for biology · 2026-04-22Psilocybin in Older Adults: Therapeutic Opportunities in Inflammation-Driven Disorders of Aging-From Depression to NeurodegenerationPreprints.org · 2026-04-15An international mega-analysis of psychedelic drug effects on brain circuit function.Nature medicine · 2026-04-01Psilocybin-assisted therapy for demoralisation in hospice patients: feasibility, safety and preliminary efficacy.BMJ supportive & palliative care · 2026-02-27Time-Dependent Effects of Rapid-Acting Antidepressants in iPSC-Derived Neurons from Treatment-Resistant Depression and Healthy Volunteers.Research square · 2026-02-12Pharmacodynamic biomarker - or psychotherapeutic process? Comment on "The role of the psychedelic experience in psilocybin treatment for treatment-resistant depression".Journal of affective disorders · 2026-02-01Psychedelics produce enduring behavioral effects and functional plasticity through mechanisms independent of structural plasticity.Neuropsychopharmacology: official publication of the American College of Neuropsychopharmacology · 2026-02-01Behavioral effects of psychedelic and non-psychedelic serotonin 2A receptor agonist drugs in pigsNeuroscience Applied · 2026-01-01Efficacy and safety of psilocybin in treatment-resistant major depression (EPIsoDE): Results of a randomized active placebo-controlled trialNeuroscience Applied · 2026-01-01A novel psychedelic 5-HT receptor agonist GM-2505: The pharmacokinetic, safety, and pharmacodynamic profile from a randomized trial healthy volunteer.Journal of psychopharmacology (Oxford, England) · 2026-01-01An exploration of the relationships between the effects of psilocybin on behavior, 5-HT receptor occupancy, and neuroplastic effects in mice.Journal of psychopharmacology (Oxford, England) · 2026-01-01A Promise Without Panacea: Psychedelic-Assisted Therapies in Modern Psychiatry.Cureus · 2026-01-01Wherefore the magic? The evolutionary role of psilocybin in naturebioRxiv · 2025-12-19Efficacy, all-cause discontinuation, and safety of serotonergic psychedelics and MDMA to treat mental disorders: A living systematic review with meta-analysis.European neuropsychopharmacology: the journal of the European College of Neuropsychopharmacology · 2025-12-01A comparative assessment of the antidepressant efficacy of ketamine, psilocybin, and fluoxetine in a chronic stress model.Scientific reports · 2025-11-26Correction: Acute and long-term effects of psilocybin on energy balance and feeding behavior in mice.Translational psychiatry · 2025-11-06Psilocybin-assisted physiotherapy for refractory motor functional neurological disorder: protocol for a randomised dose-comparison pilot study.Acta neuropsychiatrica · 2025-11-04Psychedelic compounds directly excite 5-HT2A layer V medial prefrontal cortex neurons through 5-HT2A Gq activationUNC Libraries · 2025-10-16Towards Novel Antidepressant Strategies: A Comparative Study of Ketamine, Psilocybin, and Fluoxetine in a Chronic Stress ModelResearch Square · 2025-10-07The polypharmacology of psychedelics reveals multiple targets for potential therapeutics.Neuron · 2025-10-01Publisher Correction: Psilocybin's lasting action requires pyramidal cell types and 5-HT2A receptors.Nature · 2025-10-01The Psychedelic Reset: How Psychedelics May Reshape the Corticostriatal Circuit in Anorexia NervosaCarleton undergraduate journal of science. · 2025-09-02Neuroplasticity and Neuro-Generation: The Promise of Psychedelics in Dementia CarePsychoactives · 2025-09-02A critical evaluation of psilocybin-assisted therapy protocol components from clinical trial patients, facilitators, and caregivers.Psychotherapy (Chicago, Ill.) · 2025-09-01Psilocybin biosynthesis enhancement through gene source optimization.Metabolic engineering · 2025-09-01Examining mystical experiences as a predictor of psilocybin-assisted psychotherapy for treatment-resistant depression.Journal of psychopharmacology (Oxford, England) · 2025-09-01Selective Phosphorylation of Phenols and Benzenediols by the Kinase PsiK and Variants Thereof.Angewandte Chemie (International ed. in English) · 2025-08-18Interventions to support spirituality among adults with cancer: a scoping review.Supportive care in cancer: official journal of the Multinational Association of Supportive Care in Cancer · 2025-08-02Treatment approaches and efficacy in psychedelic-induced psychosis: A systematic review.Asian journal of psychiatry · 2025-08-01204. A NOVEL, NON-HALLUCINOGENIC PSYCHEDELIC FOR THE TREATMENT OF OCD AND TIC DISORDERThe International Journal of Neuropsychopharmacology · 2025-07-31Effects of Psilocin and Psilocybin on Human 5-HT4 Serotonin and H2 Histamine Receptors in Perfused Hearts of Transgenic MicePharmaceuticals · 2025-07-06Exploring serotonergic psychedelics as a treatment for personality disorders.Neuropharmacology · 2025-07-01Molecular, haemodynamic and functional effects of LSD in the human brainmedRxiv · 2025-06-18Classic Psychedelics in Pain Modulation: Mechanisms, Clinical Evidence, and Future Perspectives.ACS chemical neuroscience · 2025-06-18Psilocybin and hallucinogenic mushrooms - ERRATUM.CNS spectrums · 2025-06-09Psilocybin's lasting action requires pyramidal cell types and 5-HT receptors.Nature · 2025-06-01The Clinical Applications of Psilocybin Therapies and Post-COVID Syndrome: A Comprehensive Narrative Review.Cureus · 2025-06-01Therapeutic emergence of dissociated traumatic memories during psilocybin treatment for anorexia nervosa.Journal of eating disorders · 2025-05-26Low (micro)doses of 2,5-dimethoxy-4-propylamphetamine (DOPR) increase effortful motivation in low-performing mice.Neuropharmacology · 2025-05-01Regulatory Challenges of Integrating Psychedelics into Mental Health SectorPsychoactives · 2025-04-22Psilocybin-Assisted suppoRtive psychoTherapy IN the treatment of prolonged Grief (PARTING) trial: protocol for an open-label pilot trial for cancer-related bereavement.BMJ open · 2025-04-15Reconsidering evidence for psychedelic-induced psychosis: an overview of reviews, a systematic review, and meta-analysis of human studies.Molecular psychiatry · 2025-03-01Compass Psychological Support Model for COMP360 Psilocybin Treatment of Serious Mental Health Conditions.The American journal of psychiatry · 2025-01-01Improved mental health outcomes and normalised spontaneous EEG activity in veterans reporting a history of traumatic brain injuries following participation in a psilocybin retreat.Frontiers in psychiatry · 2025-01-01Correction: Therapeutic and legal aspects of psilocybin in cancer-related depression.Frontiers in psychiatry · 2025-01-01Going Underground: Demographics, Services, and Best Practices Endorsed by Practitioners Providing Support for Naturalistic Psychedelic Use.Journal of psychoactive drugs · 2025-01-01Set and setting in psilocybin-assisted therapy: A qualitative study of patients with cancer and depression.General hospital psychiatry · 2025-01-01Psilocybin Therapy for Clinicians With Symptoms of Depression From Frontline Care During the COVID-19 Pandemic: A Randomized Clinical Trial.JAMA network open · 2024-12-02Psilocybin and hallucinogenic mushrooms.CNS spectrums · 2024-12-01Classification of psychedelics and psychoactive drugs based on brain-wide imaging of cellular c-Fos expression.bioRxiv: the preprint server for biology · 2024-11-23Pyramidal cell types and 5-HT receptors are essential for psilocybin's lasting drug action.bioRxiv: the preprint server for biology · 2024-11-03Psilocybin-assisted psychotherapy for existential distress: practical considerations for therapeutic application-a review.Annals of palliative medicine · 2024-11-01Human brain changes after first psilocybin usebioRxiv · 2024-10-14Psilocybin in pharmacotherapy of obsessive-compulsive disorder.Pharmacological reports: PR · 2024-10-01Psilocybin for clinical indications: A scoping review.Journal of psychopharmacology (Oxford, England) · 2024-10-01Salience, sensemaking, and setting in psilocybin microdosing: Methodological lessons and preliminary findings of a mixed method qualitative studyPhilosophical Psychology · 2024-09-26Psychedelic-assisted therapy for treating anxiety, depression, and existential distress in people with life-threatening diseases.The Cochrane database of systematic reviews · 2024-09-12Psilocybin Therapy for Females With Anorexia Nervosa: A Phase 1, Open-Label Feasibility Study.Focus (American Psychiatric Publishing) · 2024-07-01Spectral signatures of psilocybin, lysergic acid diethylamide (LSD) and ketamine in healthy volunteers and persons with major depressive disorder and treatment-resistant depression: A systematic review.Journal of affective disorders · 2024-06-15Structure of a Hallucinogen-Activated Gq-Coupled 5-HT2A Serotonin ReceptorUNC Libraries · 2024-06-07Current Understanding on Psilocybin for Major Depressive Disorder: A Review Focusing on Clinical Trials.Clinical psychopharmacology and neuroscience: the official scientific journal of the Korean College of Neuropsychopharmacology · 2024-05-31Psilocybin facilitates fear extinction: importance of dose, context, and serotonin receptorsbioRxiv · 2024-05-06Acceptability of psilocybin-assisted group therapy in patients with cancer and major depressive disorder: Qualitative analysis.Cancer · 2024-04-01Psilocybin-assisted psychotherapy for treatment resistant depression: A randomized clinical trial evaluating repeated doses of psilocybin.Med (New York, N.Y.) · 2024-03-08Development of a digital intervention for psychedelic preparation (DIPP).Scientific reports · 2024-02-19Reports of self-compassion and affect regulation in psilocybin-assisted therapy for alcohol use disorder: An interpretive phenomenological analysis.Psychology of addictive behaviors: journal of the Society of Psychologists in Addictive Behaviors · 2024-02-01Effects of psilocybin and sleep quality on brain water diffusivity and microstructure in healthy individuals and chronic cluster headache patientsNeuroscience Applied · 2024-01-01Older adults in psychedelic-assisted therapy trials: A systematic review.Journal of psychopharmacology (Oxford, England) · 2024-01-01Theorizing that Psychedelic Assisted Therapy May Play a Role in the Treatment of Trauma-Induced Personality Disorders.Journal of addiction psychiatry · 2024-01-01Knowledge gaps in psychedelic medicalisation: Preclinical and neuroimaging mechanisms.Neuroscience applied · 2024-01-01Effect of oral tryptamines on the gut microbiome of rats-a preliminary study.PeerJ · 2024-01-01Critical appraisal of evidence supporting prescription of psychedelics from clinic websites in Ontario, Canada.PloS one · 2024-01-01Development of a Digital Intervention for Psychedelic Preparation (DIPP): a theory- and person-centred approachPsyArXiv · 2023-11-22Psilocybin-assisted therapy for depression: A systematic review and dose-response meta-analysis of human studies.European neuropsychopharmacology: the journal of the European College of Neuropsychopharmacology · 2023-11-01Psychedelics promote plasticity by directly binding to BDNF receptor TrkB.Nature neuroscience · 2023-06-01Trends in drug use among nightclub and festival attendees in New York City, 2017-2022.The International journal on drug policy · 2023-05-01509. Meta-Analysis of Functional Neuroimaging Studies of the Effects of Serotonergic Psychedelics on Neural ActivityBiological Psychiatry · 2023-04-09Pharmacokinetics and Pharmacodynamics of Oral Psilocybin Administration in Healthy Participants.Clinical pharmacology and therapeutics · 2023-04-01Are psychedelics the answer to chronic pain: A review of current literature.Pain practice: the official journal of World Institute of Pain · 2023-04-01Canalization and plasticity in psychopathology.Neuropharmacology · 2023-03-15A Single Administration of Psilocybin Persistently Rescues Cognitive Deficits Caused by Adolescent Chronic Restraint Stress Without Long-Term Changes in Synaptic Protein Gene Expression in a Rat Experimental System with Translational Relevance to Depression.Psychedelic medicine (New Rochelle, N.Y.) · 2023-03-01The therapeutic potential of psychedelics: the European regulatory perspectiveThe Lancet · 2023-02-10Acute neurovascular effects of psilocybin administration in healthy humans: Implications for cerebral blood flow measurements using arterial spin labellingNeuroscience Applied · 2023-01-01Change in whole blood BDNF after escitalopram or psilocybin intervention in patients with depression and healthy controlsNeuroscience Applied · 2023-01-01A multi-metric evaluation of psilocybin effects on functional brain entropy in healthy volunteersNeuroscience Applied · 2023-01-01Among psychedelic-experienced users, only past use of psilocybin reliably predicts nature relatedness.Journal of psychopharmacology (Oxford, England) · 2023-01-01Cannabis-assisted psychotherapy for complex dissociative posttraumatic stress disorder: A case report.Frontiers in psychiatry · 2023-01-01Group psychedelic therapy: empirical estimates of cost-savings and improved access.Frontiers in psychiatry · 2023-01-01Psychedelic compounds directly excite 5-HT2A Layer 5 Pyramidal Neurons in the Prefrontal Cortex through a 5-HT2A Gq -mediated activation mechanismbioRxiv · 2022-11-15Structure-Activity Relationships for Psilocybin, Baeocystin, Aeruginascin, and Related Analogues to Produce Pharmacological Effects in Mice.ACS pharmacology & translational science · 2022-11-115-MeO-DMT modifies innate behaviors and promotes structural neural plasticity in micebioRxiv · 2022-11-03The Watts Connectedness Scale: a new scale for measuring a sense of connectedness to self, others, and world.Psychopharmacology · 2022-11-01Psychedelic medicine at a crossroads: Advancing an integrative approach to research and practice.Transcultural psychiatry · 2022-10-01Psilocybin Therapy for Treatment Resistant Depression: Prediction of Clinical Outcome by Natural Language ProcessingPsyArXiv · 2022-09-30Acute and long-term effects of psilocybin on energy balance and feeding behavior in mice.Translational psychiatry · 2022-08-11Author Correction: Psilocybin microdosers demonstrate greater observed improvements in mood and mental health at one month relative to non-microdosing controls.Scientific reports · 2022-07-28Psilocybin microdosers demonstrate greater observed improvements in mood and mental health at one month relative to non-microdosing controls.Scientific reports · 2022-06-30Psilocybin-Mediated Attenuation of Gamma Band Auditory Steady-State Responses (ASSR) Is Driven by the Intensity of Cognitive and Emotional Domains of Psychedelic Experience.Journal of personalized medicine · 2022-06-19New Paradigms of Old Psychedelics in Schizophrenia.Pharmaceuticals (Basel, Switzerland) · 2022-05-23Alternative Options for Complex, Recurrent Pain States Using Cannabinoids, Psilocybin, and Ketamine: A Narrative Review of Clinical Evidence.Neurology international · 2022-05-18Persisting decreases in state and trait anxiety post-psilocybin: A naturalistic, observational study among retreat attendeesmedRxiv · 2022-03-02[Are psychedelics fast acting antidepressant agents?].Der Nervenarzt · 2022-03-01Acute psilocybin and ketanserin effects on cerebral blood flow: 5-HT2AR neuromodulatory effects in healthy humansNeuroscience Applied · 2022-01-01Acute change in functional brain entropy following psilocybin administration in healthy volunteersNeuroscience Applied · 2022-01-01Psilocybin: crystal structure solutions enable phase analysis of prior art and recently patented examples.Acta crystallographica. Section C, Structural chemistry · 2022-01-01Psilocybin modulation of dynamic functional connectivity is associated with plasma psilocin and subjective effectsmedRxiv · 2021-12-17P.0593 Lasting effects of a single psilocybin dose on resting-state functional connectivity in healthy individualsEuropean Neuropsychopharmacology · 2021-12-01P.0828 Psilocybin enhances emotional response to music in healthy individualsEuropean Neuropsychopharmacology · 2021-12-01Adults who microdose psychedelics report health related motivations and lower levels of anxiety and depression compared to non-microdosers.Scientific reports · 2021-11-18A potential effect of psilocybin on anxiety in neurotic personality structures in adolescents.Croatian medical journal · 2021-10-31Investigation of the Structure-Activity Relationships of Psilocybin Analogues.ACS pharmacology & translational science · 2021-04-09Complete mitochondrial genome sequence of.Mitochondrial DNA. Part B, Resources · 2021-03-18A Rare Presentation of Anticholinergic Toxicity in a Young Patient Due to Over-The-Counter Cold Medicines.Cureus · 2021-03-16Sustained, Multifaceted Improvements in Mental Well-Being Following Psychedelic Experiences in a Prospective Opportunity Sample.Frontiers in psychiatry · 2021-01-01P.804A single dose of psilocybin increases synaptic density and decreases 5-HT2A receptor density in the pig brainEuropean Neuropsychopharmacology · 2020-11-01P.227 Psilocybin induces resting-state functional connectivity changes, which correlate with plasma psilocin levels and psychedelic experienceEuropean Neuropsychopharmacology · 2020-11-01Scoping Review Protocol: Mapping Psilocybin Animal ResearchQueen's University QSpace · 2020-05-20Correlation between the potency of hallucinogens in the mouse head-twitch response assay and their behavioral and subjective effects in other species.Neuropharmacology · 2020-05-01Synthesis and Biological Evaluation of Tryptamines Found in Hallucinogenic Mushrooms: Norbaeocystin, Baeocystin, Norpsilocin, and Aeruginascin.Journal of natural products · 2020-02-28P.188 Long-term effects of psilocybin on cerebral serotonin 2A receptor levels and personalityEuropean Neuropsychopharmacology · 2019-12-01P.839 Modelling the acute temporal dynamics of psilocybin psychoactive effects; relation to brain serotonin 2a receptor levelsEuropean Neuropsychopharmacology · 2019-12-01In vivo production of psilocybin in E. coli.Metabolic engineering · 2019-12-01Twenty percent better with 20 micrograms? A qualitative study of psychedelic microdosing self-rapports and discussions on YouTube.Harm reduction journal · 2019-11-28Characterization and prediction of acute and sustained response to psychedelic psilocybin in a mindfulness group retreat.Scientific reports · 2019-10-24Psilocybin-assisted mindfulness training modulates self-consciousness and brain default mode network connectivity with lasting effects.NeuroImage · 2019-08-01Psilocybin occupancy of brain serotonin 2A receptors correlates with psilocin levels and subjective experience: a [11C]Cimbi-36 PET study in humansEuropean Neuropsychopharmacology · 2019-01-01Psilocybin disrupts sensory and higher order cognitive processing but not pre-attentive cognitive processing-study on P300 and mismatch negativity in healthy volunteers.Psychopharmacology · 2018-02-01Rapid-Acting Antidepressants.Current pharmaceutical design · 2018-01-01If you give a mouse a mushroom: Behavioral effects of hallucinogens in miceeScholarship (California Digital Library) · 2017-12-31Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms.Scientific reports · 2017-10-13Psychoactive substances as a last resort-a qualitative study of self-treatment of migraine and cluster headaches.Harm reduction journal · 2017-09-05[Simple and rapid screening for psychotropic natural products using Direct Analysis in Real Time (DART)-TOFMS].Yakugaku zasshi: Journal of the Pharmaceutical Society of Japan · 2009-06-01Mismatch negativity generation in the human 5HT2A agonist and NMDA antagonist model of psychosis.Psychopharmacology · 2008-07-01Prepulse inhibition of the startle reflex and its attentional modulation in the human S-ketamine and N,N-dimethyltryptamine (DMT) models of psychosis.Journal of psychopharmacology (Oxford, England) · 2007-05-01Psychological effects of (S)-ketamine and N,N-dimethyltryptamine (DMT): a double-blind, cross-over study in healthy volunteers.Pharmacopsychiatry · 2005-11-01Hypermetabolic pattern in frontal cortex and other brain regions in unmedicated schizophrenia patients. Results from a FDG-PET study.European archives of psychiatry and clinical neuroscience · 2005-10-01Liquid Chromatography-Mass Spectrometric and Liquid Chromatography-Tandem Mass Spectrometric Determination of Hallucinogenic Indoles Psilocin and Psilocybin in “Magic Mushroom” SamplesJournal of Forensic and Sciences · 2005-03-01Liquid chromatography-mass spectrometric and liquid chromatography-tandem mass spectrometric determination of hallucinogenic indoles psilocin and psilocybin in "magic mushroom" samples.Journal of forensic sciences · 2005-03-01Neurometabolic effects of psilocybin, 3,4-methylenedioxyethylamphetamine (MDE) and d-methamphetamine in healthy volunteers. A double-blind, placebo-controlled PET study with [18F]FDG.Neuropsychopharmacology: official publication of the American College of Neuropsychopharmacology · 1999-06-01[Poisoning by the hallucinogenic mushroom hikageshibiretake (Psilocybe argentipes)--with special reference to subjective experiences during psilocybin poisoning].Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica · 1988-01-01Psychoactivity of normacromerine in animals.Life sciences · 1978-08-30Botanical and Chemical Characterisation of a Forensic Mushroom Specimen of the Genus PsilocybeJournal of the Forensic Science Society · 1966-07-01The effect of psilocybin upon the systemic, pulmonary, and coronary circulation of the intact dog.Archives internationales de pharmacodynamie et de therapie · 1962-05-01[Clinical experiences with psilocybin (CY39 Sandoz)].Psychiatria et neurologia · 1961-01-01[Clinical experiences with psilocybin Sandoz (CY39 Sandoz)].Sbornik vedeckych praci Lekarske fakulty Karlovy university v Hradci Kralove · 1961-01-01[The pharmacology of psilocybin, an ac' principle from Psilocybe mexicana Heim].Experientia · 1958-09-15