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Publication history
An Open-Label Trial Protocol to Test Menstrual Cycle Effects and Tolerance to Low-Dose Psilocybin in Healthy Menstruating Persons.Pharmacology · 2026-08-10Psilocybin-assisted therapy for treatment-resistant major depressive disorder in a public healthcare setting: a randomized controlled trial.Nature medicine · 2026-08-06A suite of engineered mice for interrogating psychedelic drug actions.Nature neuroscience · 2026-08-06The role of therapeutic alliance in psilocybin treatment for treatment-resistant depression: A post hoc path analysisJournal of Affective Disorders · 2026-08-01Retreat from racism: A psychedelic group experience for racial stress and traumaPsychedelics · 2026-07-30Childhood trauma and psychological outcomes following psychedelic use: a scoping reviewnpj Mental Health Research · 2026-07-30Comparing synthetic and biological therapy for the treatment of cluster headache: what is needed and when?Expert review of neurotherapeutics · 2026-07-23Silence is golden: Documenting the speech production of participants and support providers in psilocybin administration sessions for the treatment of post-traumatic stress disorderJournal of Psychopharmacology · 2026-07-16PSilocybin Microdose for psYCHological and Existential Distress in PALliative Care (PSYCHED-PAL): A Multi-site Phase 3 Double-blind, Placebo-controlled, Parallel-arm Clinical TrialClinicalTrials.gov · 2026-07-10Psychedelic Use, Microdosing, Motives, and Information and Product Sources Among Young Adults in the United States.Journal of psychoactive drugs · 2026-06-19Psychedelics disrupt hierarchical cortical propagations in the default mode network of humans and mice.Proceedings of the National Academy of Sciences of the United States of America · 2026-06-16Psilocybin Decreases Preference for Large Rewards Accompanied by Increased Activity of Parvalbumin Neurons With Perineuronal Nets in the Medial Prefrontal CortexEuropean Journal of Neuroscience · 2026-06-01PsiConnect: Multimodal Neuroimaging of Context-Dependent Brain and Behaviour Dynamics under PsilocybinScientific Data · 2026-05-21From Trials to Clinics: Considerations for Implementing Psychedelic-Assisted Therapy Into Clinical PracticePharmacology Research & Perspectives · 2026-05-101080 Psilocybin Elicits Non-Linear Night to Night Changes in Sleep Spectral PowerSLEEPJ · 2026-05-08Human brain changes after first psilocybin useNature Communications · 2026-05-05The Music for Subanesthetic Infusions of Ketamine randomised clinical trial: ketamine as a psychedelic treatment for highly refractory depression.The British journal of psychiatry: the journal of mental science · 2026-05-01Effects of psilocybin on personality, psychiatric symptoms, and values: Exploring mediating effects of the acute psychedelic experience.Journal of psychopharmacology (Oxford, England) · 2026-05-01Integrating the Mystical Experience Questionnaire Into a Broader Psychometric Framework: English Validation of the Psychedelic Experience Scale and Comparison of Psilocybin and LSD Sessions Across Two Controlled SettingsRepository for Publications and Research Data (ETH Zurich) · 2026-04-30“Large-Scale and Local Functional Connectivity Changes Following Psilocybin Administration in Methamphetamine Use DisorderAmerican Journal of Neuroradiology · 2026-04-24Synthesis and Characterization of Psilocybin Metabolites and Deuterated AnalogsACS Chemical Neuroscience · 2026-03-18Approved and Pipeline Pharmacological Interventions for Eating Disorders (2010-2025): 15 Years of Progress (or Lack Thereof).CNS drugs · 2026-02-01Corrigendum to "The role of the psychedelic experience in psilocybin treatment for treatment-resistant depression" [Journal of Affective Disorders, Volume 372 (2025), Pages 523-532].Journal of affective disorders · 2026-01-15Development of Psilocybe Mushroom Species Reference Material-Cultivation Parameters and Chemical Profiles.Journal of AOAC International · 2026-01-01Investigating the safety and tolerability of single-dose psilocybin for post-traumatic stress disorder: A nonrandomized open-label clinical trial.Journal of psychopharmacology (Oxford, England) · 2026-01-01A novel psychedelic 5-HT receptor agonist GM-2505: The pharmacokinetic, safety, and pharmacodynamic profile from a randomized trial healthy volunteer.Journal of psychopharmacology (Oxford, England) · 2026-01-01Psilocybin decreases reward-seeking behavior accompanied by increased activity of parvalbumin neurons with perineuronal nets in the medial prefrontal cortexbioRxiv · 2025-12-26A qualitative analysis of participant expectations and experiences of psilocybin-assisted psychotherapy for methamphetamine use disorder.Addiction (Abingdon, England) · 2025-12-22The CAnadian Network for Psychedelic-Assisted Cancer Therapy (CAN-PACT): A Multi-Phase Program Overview.Current oncology (Toronto, Ont.) · 2025-12-22Age and cannabis co-use are associated with differences in experience and perceived benefits of psilocybin: a retrospective studyPsyArXiv · 2025-12-10Investigational psilocybin treatment for post-traumatic stress disorder: a qualitative study of participant experience, trauma engagement, and differences from standard treatment.EClinicalMedicine · 2025-12-01Effects of Psilocybin on Religious and Spiritual Attitudes and Behaviors in Clergy from Various Major World Religions.Psychedelic medicine (New Rochelle, N.Y.) · 2025-12-01Qualitative Research on Psilocybin-Assisted Psychotherapy for the Treatment of Mental Disorders: A Scoping ReviewPsychedelic Medicine · 2025-11-24Salience, sensemaking, and setting in psilocybin microdosingRepository of the University of Ljubljana (University of Ljubljana) · 2025-11-18A Comparative Neurophenomenology of the Psychedelic State and Autism: Predictive Processing as a Unifying LensPsychoactives · 2025-11-14Understanding psilocybin mushrooms and aiding in setting standards for a burgeoning industry in JamaicaPhytochemistry Letters · 2025-10-01A critical evaluation of psilocybin-assisted therapy protocol components from clinical trial patients, facilitators, and caregivers.Psychotherapy (Chicago, Ill.) · 2025-09-01Psilocybin biosynthesis enhancement through gene source optimization.Metabolic engineering · 2025-09-01229. PSILOCYBIN WITH PSYCHOTHERAPEUTIC SUPPORT FOR TREATMENT-RESISTANT DEPRESSION: A PILOT CLINICAL TRIALThe international journal of neuropsychopharmacology · 2025-08-01Perspectives on Trauma Treatment, Self-Management Strategies, and Attitudes Toward Psychedelic Therapies in Individuals with Psychological Trauma Symptoms.Psychiatry and clinical psychopharmacology · 2025-07-30Therapeutic emergence of dissociated traumatic memories during psilocybin treatment for anorexia nervosa.Journal of eating disorders · 2025-05-26Age and cannabis co-use moderate experience and perceived benefits of psilocybinPsyArXiv · 2025-05-22Age and cannabis co-use moderate experience and perceived benefits of psilocybinPsyArXiv · 2025-05-22Exploring the perceived usefulness of integration support after naturalistic psychedelic experiences in people concerned about their substance use: A surveyJournal of Psychedelic Studies · 2025-04-22PsiConnect: A Multimodal Neuroimaging Study of Psilocybin-Induced Changes in Brain and BehaviourbioRxiv · 2025-04-14166. Dynamic Mediodorsal Thalamus Activity Predicts and Reflects Longitudinal Treatment Outcomes in Psilocybin Therapy for Treatment-Resistant DepressionBiological Psychiatry · 2025-04-09Pictorial Representation of Illness and Self Measure: A Putative Transdiagnostic Tool for Evaluating Therapeutic Effects of Psilocybin-Assisted Therapy in FibromyalgiaJournal of Pain · 2025-04-01A Rapid Review of Psychedelic-Assisted Therapy in the Context of Palliative Care.Journal of hospice and palliative nursing: JHPN: the official journal of the Hospice and Palliative Nurses Association · 2025-04-01A Rapid Review of Psychedelic-Assisted Therapy in the Context of Palliative Care.Journal of hospice and palliative nursing: JHPN: the official journal of the Hospice and Palliative Nurses Association · 2025-04-01Psychedelics Align Brain Activity with ContextbioRxiv · 2025-03-11The role of the psychedelic experience in psilocybin treatment for treatment-resistant depression.Journal of affective disorders · 2025-03-01Participants' Experience of Psychedelic Integration Groups and Processes: A Qualitative Thematic Analysis.Psychedelic medicine (New Rochelle, N.Y.) · 2025-03-01Compass Psychological Support Model for COMP360 Psilocybin Treatment of Serious Mental Health Conditions.The American journal of psychiatry · 2025-01-01Psilocybin: From Psychiatric Pariah to Perceived Panacea.The American journal of psychiatry · 2025-01-01Editorial: Beyond psilocybin: exploring the clinical potential of alternative and novel psychedelics.Frontiers in psychiatry · 2025-01-01Enhanced meaning in life following psychedelic use: converging evidence from controlled and naturalistic studies.Frontiers in psychology · 2025-01-01Clinical conceptualisation of PTSD in psilocybin treatment: disrupting a pre-determined and over-determined maladaptive interpretive framework.Therapeutic advances in psychopharmacology · 2025-01-01Psilocybin-assisted psychotherapy for depression and anxiety associated with life threatening illness: A phase 2b randomized controlled trial.General hospital psychiatry · 2025-01-01Psilocybin with psychotherapeutic support for treatment-resistant depression: a pilot clinical trial.Therapeutic advances in psychopharmacology · 2025-01-01Worsening suicidal ideation and prolonged adverse event following psilocybin administration in a clinical setting: case report and thematic analysis of one participant's experience.BJPsych open · 2024-12-10Worsening suicidal ideation and prolonged adverse event following psilocybin administration in a clinical setting: Case report and thematic analysis of one participant's experienceBJPsych Open · 2024-10-31“The mushroom was more alive and vibrant”: Patient reports of synthetic versus organic forms of psilocybinJournal of Psychedelic Studies · 2024-10-29Expert recommendations for Germany's integration of psychedelic-assisted therapy.BMC medical education · 2024-10-24The Afterglow Inventory (AGI) - validation of a new instrument for measuring subacute effects of classic serotonergic psychedelicsPsyArXiv · 2024-10-22Qualitative Research on Psilocybin-Assisted Psychotherapy for the Treatment of Mental Health Disorders: A Scoping Review ProtocolPsyArXiv · 2024-10-07Qualitative Research on Psilocybin-Assisted Psychotherapy for the Treatment of Mental Health Disorders: A Scoping Review ProtocolPsyArXiv · 2024-10-07Pharmacological and behavioural effects of tryptamines present in psilocybin-containing mushrooms.British journal of pharmacology · 2024-10-01Salience, sensemaking, and setting in psilocybin microdosing: Methodological lessons and preliminary findings of a mixed method qualitative studyPhilosophical Psychology · 2024-09-26B - 61 Psilocybin as a First-Line Treatment of ADHD in Adult PopulationsArchives of Clinical Neuropsychology · 2024-09-12Psychedelic use and psychological flexibility: The role of meaningful intention and decenteringJournal of Psychedelic Studies · 2024-08-16Probing the functional magnetic resonance imaging response to psilocybin in functional neurological disorder (PsiFUND): study protocolWellcome Open Res · 2024-07-24Psychedelic trip sitting, dosages and intensities: Supplementing clinical studies with anecdotal reportsJournal of Psychedelic Studies · 2024-07-17Inhibition of cytochrome P450 3A4 enzyme activity by alkaloid psilocin from magic mushrooms: potential for drug interactionsDrug Metabolism and Pharmacokinetics · 2024-04-01Psilocybin-assisted group therapy in patients with cancer diagnosed with a major depressive disorder.Cancer · 2024-04-01Psilocybin-assisted psychotherapy for treatment resistant depression: A randomized clinical trial evaluating repeated doses of psilocybin.Med (New York, N.Y.) · 2024-03-08Psychedelic-like Activity of Norpsilocin Analogues.ACS chemical neuroscience · 2024-01-17Potential analgesic effects of psychedelics on select chronic pain conditions: A survey study.European journal of pain (London, England) · 2024-01-01The safety of supported psilocybin use in Oregon.Nature medicine · 2024-01-01Trauma-Informed Care in Psychedelic Therapy Research: A Qualitative Literature Review of Evidence-Based Psychotherapy Interventions in PTSD and Psychedelic Therapy Across Conditions.Neuropsychiatric disease and treatment · 2024-01-01A scoping review of the effects of mushroom and fungus extracts in rodent models of depression and tests of antidepressant activity.Frontiers in pharmacology · 2024-01-01Evaluation of TrpM and PsiD substrate promiscuity reveals new biocatalytic capabilities.Biotechnology progress · 2024-01-01Probing the functional magnetic resonance imaging response to psilocybin in functional neurological disorder (PsiFUND): study protocol.Wellcome open research · 2024-01-01Developing a Direct Observation Measure of Therapeutic Connection in Psilocybin-Assisted Therapy: A Feasibility Study.Journal of palliative medicine · 2023-12-01An open-label pilot trial assessing tolerability and feasibility of LSD microdosing in patients with major depressive disorder (LSDDEP1).Pilot and feasibility studies · 2023-10-05Single-Dose Psilocybin Treatment for Major Depressive Disorder: A Randomized Clinical Trial.JAMA · 2023-09-05Psilocybin for treatment resistant depression in patients taking a concomitant SSRI medication.Neuropsychopharmacology: official publication of the American College of Neuropsychopharmacology · 2023-09-01"Biosynthesis of psilocybin and its nonnatural derivatives by a promiscuous psilocybin synthesis pathway in Escherichia coli".Biotechnology and bioengineering · 2023-08-01Improvement in Depression Symptoms Measured by Montgomery-Åsberg Depression Rating Scale and Quick Inventory of Depressive Symptomatology-Self Rated Items after Randomised Double-blind COMP360 Psilocybin Therapy for Treatment-resistant DepressionEuropean psychiatry: the journal of the Association of European Psychiatrists · 2023-07-19A Systematic Review of Reporting Practices in Psychedelic Clinical Trials: Psychological Support, Therapy, and Psychosocial InterventionsPsyArXiv · 2023-07-18Why didn't the TGA consult with Australian researchers and clinicians with experience in psilocybin-assisted psychotherapy for treatment-resistant major depressive disorder?The Australian and New Zealand journal of psychiatry · 2023-07-01In silico characterization of the psilocybin biosynthesis pathway.Computational biology and chemistry · 2023-06-01Assessment of Psilocybin Therapy for Patients With Cancer and Major Depression Disorder.JAMA oncology · 2023-06-01Single-dose psilocybin for a treatment-resistant episode of major depression: Impact on patient-reported depression severity, anxiety, function, and quality of life.Journal of affective disorders · 2023-04-14Optimizing outcomes in psilocybin therapy: Considerations in participant evaluation and preparation.Journal of affective disorders · 2023-04-01UNRAVELing the synergistic effects of psilocybin and environment on brain-wide immediate early gene expression in mice.bioRxiv: the preprint server for biology · 2023-02-21Cognitive liberty and the constitutionality of criminalising psilocybin mushrooms in South AfricaSouth African Journal on Human Rights · 2023-01-02The right to privacy in the decriminalisation of psilocybin mushrooms in South AfricaLaw Democracy & Development · 2023-01-01The Impact of Psilocybin on Patients Experiencing Psychiatric Symptoms: A Systematic Review of Randomized Clinical Trials.Innovations in clinical neuroscience · 2023-01-01Single-Dose Psilocybin for a Treatment-Resistant Episode of Major Depression.The New England journal of medicine · 2022-11-03Top Ten Tips Palliative Care Clinicians Should Know About Psychedelic-Assisted Therapy in the Context of Serious Illness.Journal of palliative medicine · 2022-08-01Development of an -based norbaeocystin production platform and evaluation of behavioral effects in rats.Metabolic engineering communications · 2022-06-01The efficacy of COMP360 psilocybin therapy in treatment-resistant depression: exploratory results from a phase IIb randomised controlled trialNeuroscience Applied · 2022-01-01The safety and efficacy of COMP360 psilocybin therapy in treatment-resistant depression: results from a phase IIb randomised controlled trialNeuroscience Applied · 2022-01-01The effects of psilocybin on cognitive and emotional functions in healthy participants: Results from a phase 1, randomised, placebo-controlled trial involving simultaneous psilocybin administration and preparation.Journal of psychopharmacology (Oxford, England) · 2022-01-01Race, Ethnic, and Sex Differences in Prevalence of and Trends in Hallucinogen Consumption Among Lifetime Users in the United States Between 2015 and 2019.Frontiers in epidemiology · 2022-01-01Chronic Treatment With Psilocybin Decreases Changes in Body Weight in a Rodent Model of Obesity.Frontiers in psychiatry · 2022-01-01A whole genome atlas of 81 Psilocybe genomes as a resource for psilocybin production.F1000Res · 2021-12-17Medicinal psychedelics for mental health and addiction: Advancing research of an emerging paradigm.The Australian and New Zealand journal of psychiatry · 2021-12-01Homebrewed psilocybin: can new routes for pharmaceutical psilocybin production enable recreational use?Bioengineered · 2021-12-01Psilocybin-assisted therapy for the treatment of resistant major depressive disorder (PsiDeR): protocol for a randomised, placebo-controlled feasibility trial.BMJ open · 2021-12-01Ethnoracial health disparities and the ethnopsychopharmacology of psychedelic-assisted psychotherapies.Experimental and clinical psychopharmacology · 2021-10-01Rethinking enhancement substance use: A critical discourse studies approach.The International journal on drug policy · 2021-09-01A whole genome atlas of 81 Psilocybe genomes as a resource for psilocybin production.Zenodo (CERN European Organization for Nuclear Research) · 2021-07-02Psilocybin and MDMA for the treatment of trauma-related psychopathology.International review of psychiatry (Abingdon, England) · 2021-05-01Psychedelic-Assisted Psychotherapy Practices and Human Caring Science: Toward a Care-Informed Model of TreatmentJournal of Humanistic Psychology · 2021-04-23A draft sequence reference of the Psilocybe cubensis genomeF1000Research · 2021-04-09Psychedelics and Psychedelic-Assisted Psychotherapy.Focus (American Psychiatric Publishing) · 2021-01-01People of color in North America report improvements in racial trauma and mental health symptoms following psychedelic experiences.Drugs (Abingdon, England) · 2021-01-01Development and Evaluation of a Therapist Training Program for Psilocybin Therapy for Treatment-Resistant Depression in Clinical Research.Frontiers in psychiatry · 2021-01-01A draft reference assembly of the genome.F1000Research · 2021-01-01Study Protocol for "Psilocybin as a Treatment for Anorexia Nervosa: A Pilot Study".Frontiers in psychiatry · 2021-01-01Translating Psychedelic Therapies From Clinical Trials to Community Clinics: Building Bridges and Addressing Potential Challenges Ahead.Frontiers in psychiatry · 2021-01-01Experience of Music Used With Psychedelic Therapy: A Rapid Review and Implications.Journal of music therapy · 2020-07-18Microdosing psychedelics: Demographics, practices, and psychiatric comorbidities.Journal of psychopharmacology (Oxford, England) · 2020-06-01Ethics and ego dissolution: the case of psilocybin.Journal of medical ethics · 2020-05-27Psychedelics and Psychedelic-Assisted Psychotherapy.The American journal of psychiatry · 2020-05-01Psilocybin-assisted therapy for depression: How do we advance the field?The Australian and New Zealand journal of psychiatry · 2020-03-01Rethinking Therapeutic Strategies for Anorexia Nervosa: Insights From Psychedelic Medicine and Animal Models.Frontiers in neuroscience · 2020-01-01Psilocybin-assisted therapy of major depressive disorder using Acceptance and Commitment Therapy as a therapeutic frameJournal of Contextual Behavioral Science · 2019-11-05Psychedelic microdosing benefits and challenges: an empirical codebook.Harm reduction journal · 2019-07-10Microdosing psychedelics: personality, mental health, and creativity differences in microdosers.Psychopharmacology · 2019-02-01Serotonergic Psychoactive Compounds as a Treatment for Addiction, Anxiety, and Depression: Their Efficacy and LegalityFurman University Scholar Exchange (Furman University) · 2019-01-01Microdosing Psychedelics: Personality, mental health, and creativity differences in microdosersPsyArXiv · 2018-11-02Microdosing Psychedelics: Personality, mental health, and creativity differences in microdosersPsyArXiv · 2018-11-02Psilocybin-occasioned mystical-type experience in combination with meditation and other spiritual practices produces enduring positive changes in psychological functioning and in trait measures of prosocial attitudes and behaviors.Journal of psychopharmacology (Oxford, England) · 2018-01-01Should addiction researchers be interested in psychedelic science?Drug and Alcohol Review · 2017-04-10Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial.Journal of psychopharmacology (Oxford, England) · 2016-12-01Psychedelic Psychotherapy: Insights From 25 Years of ResearchJournal of Humanistic Psychology · 2016-09-29Functional connectivity measures after psilocybin inform a novel hypothesis of early psychosis.Schizophrenia bulletin · 2013-11-01Broadband cortical desynchronization underlies the human psychedelic state.The Journal of neuroscience: the official journal of the Society for Neuroscience · 2013-09-18Implications for psychedelic-assisted psychotherapy: functional magnetic resonance imaging study with psilocybin.The British journal of psychiatry: the journal of mental science · 2012-03-01Neural correlates of the psychedelic state as determined by fMRI studies with psilocybin.Proceedings of the National Academy of Sciences of the United States of America · 2012-02-07Psilocybin occasioned mystical-type experiences: immediate and persisting dose-related effects.Psychopharmacology · 2011-12-01The administration of psilocybin to healthy, hallucinogen-experienced volunteers in a mock-functional magnetic resonance imaging environment: a preliminary investigation of tolerability.Journal of psychopharmacology (Oxford, England) · 2011-11-01The Phenomenology and Potential Religious Import of States of Consciousness Facilitated by PsilocybinArchive for the Psychology of Religion · 2008-01-01Psilocybin can occasion mystical-type experiences having substantial and sustained personal meaning and spiritual significance.Psychopharmacology · 2006-08-01Transient reinforcing effects of phenylisopropylamine and indolealkylamine hallucinogens in rhesus monkeys.Behavioural pharmacology · 2004-03-01The inhibition of food intake in the dog by LSD, mescaline, psilocin, -amphetamine and phenylisopropylamine derivativesLife Sciences · 1979-06-01Psilocin, Bufotenine and Serotonin: Historical and Biosynthetic ObservationsJournal of Psychedelic Drugs · 1979-01-01An electrographic study of psilocin and 4-methyl-alpha-methyl tryptamine (MP-809).The Journal of pharmacology and experimental therapeutics · 1963-04-01AN ELECTROGRAPHIC STUDY OF PSILOCIN AND4-METHYL-α-METHYL TRYPTAMINE (MP-809)The Journal of Pharmacology and Experimental Therapeutics · 1963-03-31Comparative effects of the administration of taraxein, d-LSD, mescaline, and psilocybin to human volunteersComprehensive Psychiatry · 1960-12-01The relationship between the metabolic fate and pharmacological actions of serotonin, bufotenine and psilocybin.The Journal of pharmacology and experimental therapeutics · 1960-10-01