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Chronic psilocin microdosing produces limited behavioral effects and does not enhance neurogenesis in ratsPharmacology Biochemistry and Behavior · 2026-10-01Defining 'psychedelic'.Journal of psychopharmacology (Oxford, England) · 2026-08-17An Investigation of Strategies to Understand and Optimize the Antidepressant Effects of Psilocybin (The OPTIMIZE Study)ClinicalTrials.gov · 2026-08-10Microdosing psychedelics: What, why, when, and how often? Insights from an international survey of people who use psychedelics.The International journal on drug policy · 2026-08-07Precision Phenotyping of Behavioral Risk and Response to Electromagnetic and Psychedelic TherapiesClinicalTrials.gov · 2026-08-04Serotonergic psychedelics induce distinct patterns of metabolic activity and covariance within biologically informed rat brain networksNature Communications · 2026-08-03Activating Neuroplasticity to ENHANCE the Perception Box Expanding Effects of PsilocybinClinicalTrials.gov · 2026-07-29A Randomized Double-masked Dose-controlled Trial to Assess the Tolerability, Safety, Subjective Experience, and Efficacy of Repeated Administration of Three Different Doses of Psilocybin Whole Mushroom for the Treatment of Obsessive-compulsive Disorder.ClinicalTrials.gov · 2026-07-23A Phase 3, Randomized, Double-Blind, Multicenter Study to Evaluate the Efficacy, Safety, and Tolerability of Psilocybin in Adults With Major Depressive Disorder (MDD)ClinicalTrials.gov · 2026-07-23Psilocybin's effect on human brain synaptic plasticity.Translational psychiatry · 2026-07-15Study Protocol for “Exploring the safety and therapeutic potential of psilocybin in the treatment of anorexia nervosa in adolescents and young adults”PLOS One · 2026-06-30Mechanistic insights toward dissociating therapeutic from psychedelic effects: bridging the gap between psychedelic research and mental health careTranslational Psychiatry · 2026-06-23Prenatal stress, excitatory-inhibitory imbalance, and ADHD risk: a hypothesis-driven perspective on psilocybin-induced neuroplasticityTranslational Psychiatry · 2026-06-05Patient perceptions towards psychedelics for musculoskeletal pain: A cross-sectional surveymedRxiv · 2026-06-01Effects of psilocybin on sleep quality and brain microstructure in chronic cluster headacheJournal of Psychopharmacology · 2026-05-29Epigenome-wide association study of psilocybin-induced methylome changes in alcohol use disorderTranslational Psychiatry · 2026-05-26Neural correlates of insight on psilocybin: a within-subjects, healthy volunteer studyJoCN Forum · 2026-05-08Advancing cancer neuroscience through stress modulation: Interdisciplinary potential of psilocybin and ketamineGeneral Hospital Psychiatry · 2026-05-01Microdosing psilocybin for major depressive disorder: study protocol for a phase II double-blind placebo-controlled randomised partial crossover trial - CORRIGENDUMBJPsych Open · 2026-05-01Psilocybin ameliorates neuropathic pain-like behaviour in mice and facilitates gabapentin-mediated analgesiaCommunications Biology · 2026-04-24Effects of a single dose of psilocybin on diet-induced weight loss in obese miceTranslational Psychiatry · 2026-04-14Observing the mind under psychedelics: conceptual metaphors used following four once-weekly macrodoses of psilocybinPhilosophical Psychology · 2026-04-10The astrocytes in the prefrontal cortex contribute to the rapid antidepressant-like effects of psilocybin in the chronic restraint stress mouse modelProgress in Neuro-Psychopharmacology and Biological Psychiatry · 2026-04-01Differential Effects of Acute and Chronic Fluoxetine on Psychedelic-Induced Behavior in Mice: Implications for Clinical Trials.ACS pharmacology & translational science · 2026-03-13Safety, Feasibility, and Tolerability of Psilocybin Treatment for Individuals With Functional Impairment Related to Mood, Anxiety, Trauma and/or Addiction Symptoms: An Open-label Proof-of-concept StudyClinicalTrials.gov · 2026-03-11Psychedelic therapy and cultural humility.Translational psychiatry · 2026-02-27Safety and Efficacy of Microdosing Psilocybin over 8 Weeks for Major Depressive Disorder: A Randomized Clinical TrialResearch Square · 2026-02-23Microdosing psilocybin for major depressive disorder: study protocol for a phase II double-blind placebo-controlled randomised partial crossover trial.BJPsych open · 2026-02-16We Licked the Toads so You Don't Have to: A Comprehensive Analysis of the Chemical Syntheses of the Classical Psychedelics Bufotenin(e) and 5-Methoxy-N,N-Dimethyltryptamine.ChemMedChem · 2026-02-01Regarding "The molecular mechanisms through which psilocybin prevents suicide: evidence from network pharmacology and molecular docking analyses".Translational psychiatry · 2026-01-31From trials to clinics: investigators' perspectives on translating psychedelic research into clinical care.Translational behavioral medicine · 2026-01-07Global Trends in Psychedelic Microdosing: Demographics, Substance Testing Behavior, and Patterns of Use.Journal of psychoactive drugs · 2026-01-01Preferences, Perceptions, and Environmental Considerations of Natural and Synthetic Psychedelic Substances: Findings from the Global Psychedelic Survey.Journal of psychoactive drugs · 2026-01-01Microdosing Psychedelics to Improve MoodClinicalTrials.gov · 2025-12-30Negative affective bias in depression following treatment with psilocybin or escitalopram - a secondary analysis from a randomized trial.Translational psychiatry · 2025-11-13Correction: Synergistic, multi-level understanding of psychedelics: three systematic reviews and meta-analyses of their pharmacology, neuroimaging and phenomenologyTranslational Psychiatry · 2025-11-12Psychedelics and ketamine/esketamine in depressive disorders: biological mechanisms and associated neuroimaging and clinical changes.Translational psychiatry · 2025-10-31Psilocybin Enhances Cued Fear Extinction and Extinction Recall in Stress-Naïve, Acutely Stressed, and Chronically Stressed Mice.ACS pharmacology & translational science · 2025-10-10Differential effects of psilocybin and lisuride on serotonin and dopamine neuronal activity and behavior.Progress in neuro-psychopharmacology & biological psychiatry · 2025-10-02Psilocybin-assisted therapy for treatment-resistant depression in the US: a model-based cost-effectiveness analysis.Translational psychiatry · 2025-08-29The Medial Prefrontal Cortex Modulates Psychedelic-like Effects of PsilocinACS Pharmacology & Translational Science · 2025-08-08363. DIFFERENTIAL EFFECTS OF PSILOCYBIN AND LISURIDE ON SEROTONIN AND DOPAMINE NEURONAL ACTIVITY AND BEHAVIORThe international journal of neuropsychopharmacology · 2025-08-01The effect of psychedelic microdosing on animal behavior: A review with recommendations for the field.Neuroscience and biobehavioral reviews · 2025-07-01The molecular mechanisms through which psilocybin prevents suicide: evidence from network pharmacology and molecular docking analyses.Translational psychiatry · 2025-06-16Evaluation of behavioural and neurochemical effects of psilocybin in mice subjected to chronic unpredictable mild stress.Translational psychiatry · 2025-06-14The Selective Serotonin 5-HT Receptor Agonist ()-3-(2,5-Dimethoxy-4-(trifluoromethyl)phenyl)piperidine (LPH-5) Induces Persistent and Robust Antidepressant-Like Effects in Rodents.ACS pharmacology & translational science · 2025-06-13Ergotamine enhances circadian amplitude and diurnally mitigates nitroglycerin-induced mechanical hypersensitivity.The journal of headache and pain · 2025-05-23Psychedelics and Eating Disorders: Exploring the Therapeutic Potential for Anorexia Nervosa and Beyond.ACS pharmacology & translational science · 2025-04-11166. Dynamic Mediodorsal Thalamus Activity Predicts and Reflects Longitudinal Treatment Outcomes in Psilocybin Therapy for Treatment-Resistant DepressionBiological Psychiatry · 2025-04-09Therapeutic Potential of Psilocybin-Assisted Therapy in Hospice and Palliative CareRevista Cacto - Ciência Arte Comunicação em Transdisciplinaridade Online · 2025-04-03Intravenous psilocybin induces dose-dependent changes in functional network organization in rat cortex.Translational psychiatry · 2025-03-25Pain and Perception: Exploring Psychedelics as Novel Therapeutic Agents in Chronic Pain Management.Current pain and headache reports · 2025-01-07Psilocybin rewires specific mouse cortical networks in lasting waysThe Transmitter · 2025-01-01Mushroom bioactives-polysaccharides to psilocybin: a viewpoint on the therapeutic use of mushrooms for consumers and patients for health and neuroplasticityTranslational Food Sciences · 2025-01-01Characteristics of Ongoing Clinical Trials of Psychogenic Substances for Psychiatric Disorders.Journal of clinical psychopharmacology · 2025-01-01Efficacy and Safety of COMP360 Psilocybin Therapy in Anorexia Nervosa: a Proof-of-concept StudyClinicalTrials.gov · 2024-12-04Psilocybin-assisted neurofeedback for the improvement of executive functions: a randomized semi-naturalistic-lab feasibility study.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024-12-02Moving psychedelic-assisted therapies from promising research into routine clinical practice: Lessons from the field of implementation science.Translational behavioral medicine · 2024-11-25Psilocybin increases optimistic engagement over time: computational modelling of behaviour in rats.Translational psychiatry · 2024-09-30Rapid-acting antidepressant drugs modulate affective bias in rats.Science translational medicine · 2024-01-10Effects of psilocybin and sleep quality on brain water diffusivity and microstructure in healthy individuals and chronic cluster headache patientsNeuroscience Applied · 2024-01-01Keeping the promise: a critique of the current state of microdosing research.Frontiers in psychiatry · 2024-01-01Psilocybin-induced default mode network hypoconnectivity is blunted in alcohol-dependent rats.Translational psychiatry · 2023-12-14The Psychedelic,-Dipropyltryptamine Prevents Seizures in a Mouse Model of Fragile X Syndrome via a Mechanism that Appears Independent of Serotonin and Sigma1 Receptors.ACS pharmacology & translational science · 2023-10-13Transient Elevation of Plasma Glucocorticoids Supports Psilocybin-Induced Anxiolysis in Mice.ACS pharmacology & translational science · 2023-08-11The Safety and Efficacy of Psilocybin in Participants With Treatment Resistant DepressionClinicalTrials.gov · 2023-04-24Receptor Binding Profiles for Tryptamine Psychedelics and Effects of 4-Propionoxy--dimethyltryptamine in Mice.ACS pharmacology & translational science · 2023-04-14Going on Trial: Serotonin drug; psilocybin phase 2; placebo response dataThe Transmitter · 2023-01-01Company on brink takes psilocybin to trial for fragile X syndromeThe Transmitter · 2023-01-01Going on Trial: Arbaclofen reboot; cell implants; psilocybin microdosesThe Transmitter · 2023-01-01Set and setting in microdosing: an oft-overlooked principle.Psychopharmacology · 2022-12-01Structure-Activity Relationships for Psilocybin, Baeocystin, Aeruginascin, and Related Analogues to Produce Pharmacological Effects in Mice.ACS pharmacology & translational science · 2022-11-11A Double-Blind Trial of Psilocybin-Assisted Treatment of Alcohol DependenceClinicalTrials.gov · 2022-11-08Macrodosing to microdosing with psychedelics: Clinical, social, and cultural perspectives.Transcultural psychiatry · 2022-10-01Microdosing with classical psychedelics: Research trajectories and practical considerations.Transcultural psychiatry · 2022-10-01Multicentre Study To Assess Safety And Efficacy Of Psilocybin In Patients With Treatment-Resistant Depression Following Completion Of COMP 001 And COMP 003 Trials (P-TRD LTFU)ClinicalTrials.gov · 2022-09-22Molecular Structure, Reactivity and Spectroscopic Properties of Hallucinogens Psilocybin, Mescaline and their Derivatives - A Computational StudyLetters in Applied NanoBioScience · 2022-09-17Psilocybin as a healerConsciousness Spirituality & Transpersonal Psychology · 2022-09-12Long-term transformative effects and integration challenges of psychedelic experiencesConsciousness Spirituality & Transpersonal Psychology · 2022-09-12Acute and long-term effects of psilocybin on energy balance and feeding behavior in mice.Translational psychiatry · 2022-08-11Microdosing with psilocybin mushrooms: a double-blind placebo-controlled study.Translational psychiatry · 2022-08-02Evaluation of Psilocybin in Anorexia Nervosa: Safety and EfficacyClinicalTrials.gov · 2022-07-25A Single Method for 127 Recommended and Additional DUID Drugs in Blood and Urine by LC-MS-MS.Journal of analytical toxicology · 2022-07-14MSR20 Challenges in the Development of Economic Evaluations for Psychedelics in Treatment of DepressionValue in Health · 2022-06-24Psychedelic perceptions: mental health service user attitudes to psilocybin therapy.Irish journal of medical science · 2022-06-01Psilocin acutely alters sleep-wake architecture and cortical brain activity in laboratory miceTranslational Psychiatry · 2022-02-23Microdosing psychedelics: Subjective benefits and challenges, substance testing behavior, and the relevance of intention.Journal of psychopharmacology (Oxford, England) · 2022-01-01Psilocybin therapy increases cognitive and neural flexibility in patients with major depressive disorder.Translational psychiatry · 2021-11-08Psilocin, LSD, mescaline, and DOB all induce broadband desynchronization of EEG and disconnection in rats with robust translational validityTranslational Psychiatry · 2021-10-02Psilocybin-induced changes in brain network integrity and segregation correlate with plasma psilocin level and psychedelic experienceEuropean Neuropsychopharmacology · 2021-09-01Discriminative Stimulus Effects of Substituted Tryptamines in Rats.ACS pharmacology & translational science · 2021-04-09Psilocybin-Assisted Group Therapy and Attachment: Observed Reduction in Attachment Anxiety and Influences of Attachment Insecurity on the Psilocybin Experience.ACS pharmacology & translational science · 2021-04-09Investigation of the Structure-Activity Relationships of Psilocybin Analogues.ACS pharmacology & translational science · 2021-04-09Acute and Sustained Reductions in Loss of Meaning and Suicidal Ideation Following Psilocybin-Assisted Psychotherapy for Psychiatric and Existential Distress in Life-Threatening Cancer.ACS pharmacology & translational science · 2021-04-09Ethical Concerns about Psilocybin Intellectual Property.ACS pharmacology & translational science · 2021-04-09Spontaneous and deliberate creative cognition during and after psilocybin exposure.Translational psychiatry · 2021-04-08Psilocybin-induced changes in brain network integrity and segregation correlate with plasma psilocin level and psychedelic experiencebioRxiv · 2021-02-05Referee report. For: Development of a physiologically based pharmacokinetic (PBPK) model of psilocybin and psilocin from magic mushroom in rats and humans [version 1; peer review: 1 approved with reservations, 1 not approved]Faculty of 1000 Research Ltd · 2021-01-01P.227 Psilocybin induces resting-state functional connectivity changes, which correlate with plasma psilocin levels and psychedelic experienceEuropean Neuropsychopharmacology · 2020-11-01Microdosing psychedelics: Demographics, practices, and psychiatric comorbidities.Journal of psychopharmacology (Oxford, England) · 2020-06-01Global Drug SurveyPsyArXiv · 2020-04-12Global Drug SurveyPsyArXiv · 2020-04-12Psychedelic Research and the Need for Transparency: Polishing Alice's Looking Glass.Frontiers in psychology · 2020-01-01Psychedelic microdosing benefits and challenges: an empirical codebook.Harm reduction journal · 2019-07-10Microdosing psychedelics: personality, mental health, and creativity differences in microdosers.Psychopharmacology · 2019-02-01Microdosing Psychedelics: Personality, mental health, and creativity differences in microdosersPsyArXiv · 2018-11-02Microdosing Psychedelics: Personality, mental health, and creativity differences in microdosersPsyArXiv · 2018-11-02Spirituality and Hallucinogen Use: Results from a Pilot Study among College StudentsInternational Journal of Transpersonal Studies · 2012-06-30Crystal structures of the Teonanácatl hallucinogens. Part I. Psilocybin C12 H17 N2 O4 PJournal of the Chemical Society Perkin Transactions 2 · 1974-01-01Crystal structures of the Teonanácatl hallucinogens. Part II. Psilocin, C12 H15 N2 OJ. Chem. Soc., Perkin Trans. 2 · 1974-01-01Synthesis of the sulphur analogue of psilocin and some related compoundsJournal of the Chemical Society, Perkin Transactions 1 · 1971-12-31Occurrence of psilocybin in the sporophores of Psilocybe semilanceataTransactions of the British Mycological Society · 1969-10-01