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A Randomized, Double-Blind, Placebo-Controlled Single-Ascending-Dose Study to Identify a Subperceptual Dose of Psilocybin in Healthy AdultsPharmaceuticals · 2026-09-21An Open-Label, Dose-Escalation Trial of Psilocybin-Assisted Therapy for Bipolar II Depression.The Journal of clinical psychiatry · 2026-09-21A randomized crossover trial comparing the acute physiological and psychological effects of botanical formulations of oral psilocybin, oral psilocin, and sublingual psilocin.Journal of psychopharmacology (Oxford, England) · 2026-08-29Distinct response of resting-state brain networks to psilocybin in autismmedRxiv · 2026-08-22Real-world use, safety, and mental health efficacy of regulated psilocybin services in Oregon and ColoradomedRxiv · 2026-08-12Convergent neuroimmune signaling underlying rapid antidepressant response to ketamine and psychedelics.Molecular psychiatry · 2026-07-28Synthesis and Biological Evaluation of 4-Bromo-dimethyltryptamine (4-Br-DMT): A Synthetic Building Block for Future Analog Development.ACS omega · 2026-07-07The need for another tool: Australian healthcare professionals on the use of psilocybin for existential distress in people with cancerBMC Medicine · 2026-07-06Mechanistic insights toward dissociating therapeutic from psychedelic effects: bridging the gap between psychedelic research and mental health careTranslational Psychiatry · 2026-06-23Psilocybin-Assisted Therapy for Prolonged GriefClinicalTrials.gov · 2026-06-23Mapping cognitive-behavioral approach in psychedelic-assisted treatment: a systematic review across phases with classic and non-classic psychedelics.European archives of psychiatry and clinical neuroscience · 2026-06-01Long-Term Efficacy of Psilocybin with Adjunct Psychotherapy in Treatment-Resistant Major Depression: 6- and 12-Month Naturalistic Follow-Up of a Phase 2b TrialPsychotherapy and Psychosomatics · 2026-05-27Insights from the psychedelic experience integration session: Verbatims differentiate 3-month abstinence in alcohol use disorder with depressive symptoms.Journal of affective disorders · 2026-05-01Efficacy and Safety of Psilocybin in Treatment-Resistant Major DepressionJAMA Psychiatry · 2026-05-01Comparing single- and repeat-dose psilocybin with active placebo for migraine prevention in an exploratory randomized controlled clinical trial.Headache · 2026-04-01Methodological moderators of psilocybin-assisted therapy in depression: A systematic review and meta-analysisNeuroscience & Biobehavioral Reviews · 2026-04-01Psychedelic-assisted pharmacotherapy: clinical applications and regulatory considerations.Expert opinion on pharmacotherapy · 2026-04-01Safety and Efficacy of Monoamine Oxidase Inhibitors in Patients Who Use Psychoactive Substances: Potential Drug Interactions and Substance Use Disorder Treatment Data.CNS drugs · 2026-03-01Compassionate use of psilocybin for treatment-resistant depression in Germany.The lancet. Psychiatry · 2026-02-01PSILOCYBIN IN PSYCHIATRIC PRACTICE AND PSYCHEDELIC-ASSISTED THERAPY FOR TREATMENT-RESISTANT DEPRESSIONInternational Journal of Innovative Technologies in Social Science · 2026-01-28Dynamic response of intrinsic connectivity networks to low-dose psilocybin during face matching in autistic adultsNeuroscience Applied · 2026-01-01Low dose psilocybin differentially alters resting-state network connectivity in autistic and non-autistic peopleNeuroscience Applied · 2026-01-01Psilocybin increases connectivity between unimodal and transmodal networks in healthy volunteers listening to musicNeuroscience Applied · 2026-01-01Effects of low-dose psilocybin on EEG markers of sensory processing in autistic and non-autistic adultsNeuroscience Applied · 2026-01-01Metastability of resting-state bold fMRI as a reliable biomarker of individual brain dynamics: An interrogation of within-subject variability as a function of total acquisition time.Network neuroscience (Cambridge, Mass.) · 2026-01-01Towards "unmakable" psychedelics: SAR exploration of psilocin analogs obtained by a HATU-mediated amide coupling strategyEuropean Journal of Medicinal Chemistry Reports · 2025-12-01[Acceptance of psilocybin-assisted therapy in German-speaking countries].Der Nervenarzt · 2025-11-01Psychedelics and ketamine/esketamine in depressive disorders: biological mechanisms and associated neuroimaging and clinical changes.Translational psychiatry · 2025-10-31Ethical issues with psychedelic-assisted treatments in psychiatry: A systematic scoping review.Psychological medicine · 2025-09-29Novel perspectives for glutamatergic strategies, psychedelics and antipsychotic augmentation in Treatment Resistant Depression: A narrative reviewClinical Neuropsychopharmacology and Addiction · 2025-09-24631. PSILOCYBIN AND KETANSERIN VS RTMS IN TREATMENT-RESISTANT DEPRESSION: ENHANCING TOLERABILITY BY MITIGATING PSYCHEDELIC EFFECTSThe international journal of neuropsychopharmacology · 2025-08-01Psilocybin in alcohol use disorder and comorbid depressive symptoms: Results from a feasibility randomized clinical trial.Addiction (Abingdon, England) · 2025-07-24Psilocybin therapy for mood dysfunction in Parkinson's disease: an open-label pilot trial.Neuropsychopharmacology: official publication of the American College of Neuropsychopharmacology · 2025-07-01Prolonged hallucinogenic effects following Psilocybe cubensis ingestion: Case reportThe poison. · 2025-06-30Acute Effects and Pharmacokinetics of LSD after Paroxetine or Placebo Pre-Administration in a Randomized, Double-Blind, Cross-Over Phase I Trial.Clinical pharmacology and therapeutics · 2025-06-01Pictorial Representation of Illness and Self Measure: A Putative Transdiagnostic Tool for Evaluating Therapeutic Effects of Psilocybin-Assisted Therapy in FibromyalgiaJournal of Pain · 2025-04-01A systematic review of participant diversity in psychedelic-assisted psychotherapy trials.Psychiatry research · 2025-03-01A Field-Wide Review and Analysis of Study Materials Used in Psilocybin Trials: Assessment of Two Decades of Research.Psychedelic medicine (New Rochelle, N.Y.) · 2025-03-01Exploring the Potential of Psychedelics in the Treatment of Headache Disorders: Clinical Considerations and Exploratory Insights.Current pain and headache reports · 2025-01-16Psychedelics assisting therapy, or therapy assisting psychedelics? The importance of psychotherapy in psychedelic-assisted therapy.Frontiers in psychology · 2025-01-01Psilocybin as a Disease-Modifying Drug-A Salutogenic Approach in Psychiatry.Deutsches Arzteblatt international · 2024-12-27Psilocybin Therapy for Clinicians With Symptoms of Depression From Frontline Care During the COVID-19 Pandemic: A Randomized Clinical Trial.JAMA network open · 2024-12-02Psilocybin-assisted psychotherapy improves psychiatric symptoms across multiple dimensions in patients with cancer.Nature. Mental health · 2024-11-01Psychedelic-assisted psychotherapy: where is the psychotherapy research?Psychopharmacology · 2024-08-01Engaging Mood Brain Circuits with Psilocybin (EMBRACE): a study protocol for a randomized, placebo-controlled and delayed-start, neuroimaging trial in depression.Trials · 2024-07-03SPONTANEOUS CHANGES IN CIGARETTE SMOKING FOLLOWING PSILOCYBIN-ASSISTED TREATMENT FOR ALCOHOL USE DISORDERDrug and Alcohol Dependence · 2024-07-01Effect of chemically synthesized psilocybin and psychedelic mushroom extract on molecular and metabolic profiles in mouse brain.Molecular psychiatry · 2024-07-01Spectral signatures of psilocybin, lysergic acid diethylamide (LSD) and ketamine in healthy volunteers and persons with major depressive disorder and treatment-resistant depression: A systematic review.Journal of affective disorders · 2024-06-15Psilocybin does not induce the vulnerability marker HSP70 in neurons susceptible to Olney's lesions.European archives of psychiatry and clinical neuroscience · 2024-06-01Predicting the outcome of psilocybin treatment for depression from baseline fMRI functional connectivity.Journal of affective disorders · 2024-05-15Longitudinal associations between psychedelic use and meditation practices in the United States and the United Kingdom.Psychological medicine · 2024-04-01A comparison between psilocybin and esketamine in treatment-resistant depression using number needed to treat (NNT): A systematic review.Journal of affective disorders · 2024-04-01Psychedelics for alzheimer's disease-related dementia: Unveiling therapeutic possibilities and pathways.Ageing research reviews · 2024-04-01Ethical considerations for psychedelic-assisted therapy in military clinical settings.Journal of medical ethics · 2024-03-20Neural effects of psilocybin-treatment in patients with treatment-resistant depressionNeuroscience Applied · 2024-01-01Theorizing that Psychedelic Assisted Therapy May Play a Role in the Treatment of Trauma-Induced Personality Disorders.Journal of addiction psychiatry · 2024-01-01Knowledge gaps in psychedelic medicalisation: Clinical studies and regulatory aspects.Neuroscience applied · 2024-01-01The therapeutic alliance between study participants and intervention facilitators is associated with acute effects and clinical outcomes in a psilocybin-assisted therapy trial for major depressive disorder.PloS one · 2024-01-01Present and future of metabolic and metabolomics studies focused on classical psychedelics in humans.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2023-12-31Engaging Mood Brain Circuits with Psilocybin (EMBRACE): a study protocol for a randomized, proof-of-principle, placebo-controlled and crossover, neuroimaging trial in depressionResearch Square · 2023-12-28Perceptions of psychedelic-assisted therapy among Black Americans.Journal of mood and anxiety disorders · 2023-12-01The entropic heart: Tracking the psychedelic state via heart rate dynamicsbioRxiv · 2023-11-09Songs of Life: Psychedelic-Assisted Psychotherapy and Deleuze and Guattari’s ‘Desiring-Production’Deleuze and Guattari Studies · 2023-10-27Assessing the risk of symptom worsening in psilocybin-assisted therapy for depression: A systematic review and individual participant data meta-analysis.Psychiatry research · 2023-09-01Distinctive Molecular and Metabolic Profiles of Chemically Synthesized Psilocybin and Psychedelic Mushroom ExtractResearch Square · 2023-07-20A critical evaluation of QIDS-SR-16 using data from a trial of psilocybin therapy versus escitalopram treatment for depression.Journal of psychopharmacology (Oxford, England) · 2023-07-01ID: 212703 Augmenting rTMS With Psilocybin-Assisted Psychotherapy (PAP) for PTSD: A Proof-of-Concept Study DesignNeuromodulation Technology at the Neural Interface · 2023-06-01Global species diversity and distribution of the psychedelic fungal genus.Heliyon · 2023-06-01[Attitudes of Mental Health Experts Towards Psilocybin].Fortschritte der Neurologie-Psychiatrie · 2023-03-01Personal Psychedelic Use Is Common Among a Sample of Psychedelic Therapists: Implications for Research and Practice.Psychedelic medicine (New Rochelle, N.Y.) · 2023-03-01Effect of psilocybin on decision-making and motivation in the healthy rat.Behavioural brain research · 2023-02-25Efficacy and Safety of Psychedelics in Treating Anxiety Disorders.Ochsner journal · 2023-01-01Altered states of leadership: mindfulness meditation, psychedelic use, and leadership development.Frontiers in psychology · 2023-01-01Psilocybin containing mushrooms: a rapidly developing biotechnology industry in the psychiatry, biomedical and nutraceutical fields.3 Biotech · 2022-12-01The Watts Connectedness Scale: a new scale for measuring a sense of connectedness to self, others, and world.Psychopharmacology · 2022-11-01Synthesis, Structural Characterization, and Pharmacological Activity of Novel Quaternary Salts of 4-Substituted Tryptamines.ACS omega · 2022-07-19Mapping Pharmacologically-induced Functional Reorganisation onto the Brain’s Neurotransmitter LandscapebioRxiv · 2022-07-13An Overview on the Taxonomy, Phylogenetics and Ecology of the Psychedelic Genera Psilocybe, Panaeolus, Pluteus and GymnopilusFrontiers in Forests and Global Change · 2022-05-23Psilocybin-induced takotsubo cardiomyopathy.BMJ case reports · 2022-05-17Psychoactive Drugs in the Management of Post Traumatic Stress Disorder: A Promising New Horizon.Cureus · 2022-05-01The mushroom, the frog, and the rainbow of desire: A participatory-psychedelic spiritual emergence.The International Journal of Transpersonal Studies · 2022-03-18Methodological challenges in psychedelic drug trials: Efficacy and safety of psilocybin in treatment-resistant major depression (EPIsoDE) - Rationale and study design.Neuroscience applied · 2022-01-01Psychedelics and Psychotherapy: Cognitive-Behavioral Approaches as Default.Frontiers in psychology · 2022-01-01A Quantitative and Qualitative Report of Psilocybin Induced Mystical-Type Experiences and Their Relation to Lasting Positive EffectsPsyArXiv · 2021-12-14P.0421 Efficacy and safety of psilocybin in treatment-resistant major depression (EPIsoDE) - study design, rationale and current statusEuropean Neuropsychopharmacology · 2021-12-01The Potential Role of Psychedelic Drugs in Mental Health Care of the Future.Pharmacopsychiatry · 2021-07-01Psychedelics in Psychiatry: Neuroplastic, Immunomodulatory, and Neurotransmitter Mechanisms.Pharmacological reviews · 2021-01-01People of color in North America report improvements in racial trauma and mental health symptoms following psychedelic experiences.Drugs (Abingdon, England) · 2021-01-01Development and Evaluation of a Therapist Training Program for Psilocybin Therapy for Treatment-Resistant Depression in Clinical Research.Frontiers in psychiatry · 2021-01-01Evaluating the Potential Use of Serotonergic Psychedelics in Autism Spectrum Disorder.Frontiers in pharmacology · 2021-01-01Self-Reported Illicit Drug Use Among Norwegian University and College Students. Associations With Age, Gender, and Geography.Frontiers in psychiatry · 2020-01-01Psychedelic fungus (Psilocybe sp.) authentication in a case of illegal drug traffic: sporological, molecular analysis and identification of the psychoactive substance.Science & justice: journal of the Forensic Science Society · 2019-01-01Psychedelic Drugs in Biomedicine.Trends in pharmacological sciences · 2017-11-01The "Endless Trip" among the NPS Users: Psychopathology and Psychopharmacology in the Hallucinogen-Persisting Perception Disorder. A Systematic Review.Frontiers in psychiatry · 2017-01-01Functional connectivity measures after psilocybin inform a novel hypothesis of early psychosis.Schizophrenia bulletin · 2013-11-01Implications for psychedelic-assisted psychotherapy: functional magnetic resonance imaging study with psilocybin.The British journal of psychiatry: the journal of mental science · 2012-03-01Neural correlates of the psychedelic state as determined by fMRI studies with psilocybin.Proceedings of the National Academy of Sciences of the United States of America · 2012-02-07Mismatch negativity generation in the human 5HT2A agonist and NMDA antagonist model of psychosis.Psychopharmacology · 2008-07-01SAR of Psilocybin Analogues: Discovery of a Selective 5-HT2C Agonist.ChemInform · 2005-12-13The Meixner test in the detection of α-amanitin and false-positive reactions caused by psilocin and 5-substituted tryptaminesAnnals of Emergency Medicine · 2004-08-01What geometric visual hallucinations tell us about the visual cortex.Neural computation · 2002-03-01The occurrence of psilocybin in Gymnopilus species.Lloydia · 1978-01-01Electroencephalographic and behavioral effects of 4-phosphoryloxy N, N-dimethyltryptamine (psilocybin) on the New Zealand albino rabbitUA Campus Repository (The University of Arizona) · 1976-12-31A comparison of psychotomimetic drug effects on rat brain norepinephrine metabolism.The Journal of pharmacology and experimental therapeutics · 1974-03-30The effect of bufotenine, melatonin, psilocybin, and related compounds on the 5-hydroxytryptamine excitatory receptors of Helix aspersa neuronsComparative and General Pharmacology · 1972-03-01PSILOCYBIN-INDUCED CHANGES IN PSYCHOLOGIC FUNCTION, ELECTROENCEPHALOGRAM, AND LIGHT-EVOKED POTENTIALS IN HUMAN SUBJECTSMayo Clinic Proceedings · 1968-03-01