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Psilocin analogs II. Synthesis of 3-[2-(dialkylamino)ethyl]-, 3-[2-(N-methyl-N-alkylamino)ethyl]-, and 3-[2-(cycloalkylamino)ethyl]indol-4-ols

AbstractStructural alteration of theNb-substituents of psilocin (3-[2-dimethylamino)ethyl]indol-4-ol) (12a) has led to a number of compounds containing known pharmacophoric groups. Further, it is hoped that the subtle changes in the nature of these substituents may lead to a clearer understanding of the structure-activity relationships of the 4-hydroxytryptamine hallucinogens.

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Bibliographic context

Journal: Journal of Heterocyclic Chemistry
Date: 1980-12-31
Source: Crossref
DOI: 10.1002/jhet.5570180131
PubMed: Unavailable

Authors

Repke David B.Ferguson Wilfred J.Bates Dallas K.

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Topics and keywords

psilocin General Other

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24 referenced DOIs found in stored source metadata. 3 indexed papers cite this DOI.

Open citation network

10.1002/jps.2600600819 10.1016/s0021-9673(01)81101-8 10.1016/0024-3205(68)90200-2 10.1016/b978-0-08-012039-3.50021-x 10.1021/jm00250a015 10.1038/221537a0 10.1021/jm00234a010 10.1007/bf00431735 10.1016/s0022-3565(25)25699-3 10.1021/jm00221a024 10.1021/jm00318a006 10.1021/jm00265a004

Indexed papers citing this DOI

Psilocin analogs. III. Synthesis of 5-methoxy- and 5-hydroxy-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indoles1982-06-30 ChemInform Abstract: PSILOCIN ANALOGS. PART2. SYNTHESIS OF3-(2-(DIALKYLAMINO)ETHYL)-, 3-(2-(N-METHYL-N-ALKYLAMINO)ETHYL)-, AND3-(2-(CYCLOALKYLAMINO)ETHYL)INDOL-4-OLS1981-08-03 Psilocin analogs II. Synthesis of 3-[2-(dialkylamino)ethyl]-, 3-[2-(N-methyl-N-alkylamino)ethyl]-, and 3-[2-(cycloalkylamino)ethyl]indol-4-ols1980-12-31

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