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Psilocybin and psilocin research index

Find psilocybin and psilocin papers, preprints, trials, and citations with clear source context.

Searches titles, authors, journals, identifiers, indexed metadata, and derived research topics. Use Filters to narrow by source, status, substance, study type, or date.

Database 4,961 indexed records Auto-updated on Aug 19, 2026 01:24 UTC

Executed search Topic: Drug Interactions 272 matching records are displayed.

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Database

4,742 Psilocybin Records 673 Psilocin Records 1,461 Journals 66 Research Topics

Published 4,223 Peer-reviewed / formal records Preprints 435 Marked as not peer reviewed Clinical trials 300 ClinicalTrials.gov records R toolkit visNetwork Bibliometrics, live SQLite analysis, HTML graph, and PDF export

Top journals 1,461 indexed journals

Journal	Records
Journal of psychopharmacology (Oxford, England)	148
Journal of psychoactive drugs	97
Frontiers in psychiatry	90
Psychopharmacology	85
Neuroscience Applied	57
Journal of Psychedelic Studies	48
Psychedelic medicine (New Rochelle, N.Y.)	39
Scientific reports	37
Biological Psychiatry	32
Journal of affective disorders	32

Research topics 66 topic filters

Depression 1,737 Receptor Pharmacology 1,281 Safety 1,203 Mechanism of Action 1,072 Review Article 1,072 Clinical Trial 977 Anxiety 883 Addiction 824 Pharmacology 752 General 538 Aging 524 Animal Study 524 Observational Study 515 Brain Imaging 481 Treatment-Resistant Depression 417 Emotional Processing 409 PTSD 400 Neuroplasticity 399

Source coverage 8 active sources

Source	Count	Share	Status
PubMed	2,566	51.7%	Active
OpenAlex	1,155	23.3%	Active
Crossref	405	8.2%	Active
ClinicalTrials.gov	300	6%	Active
Europe PMC	188	3.8%	Active
PsyArXiv	186	3.7%	Active
bioRxiv	123	2.5%	Active

Publication timeline 3,858 dated records

3,858 records since 2020

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Substances Psilocybin 4742 Psilocin 673

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Executed search Topic: Drug Interactions 272 matching records are displayed.

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272 matching records for Topic: Drug Interactions.

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From Altered States to Altered Trajectories and From Molecules to Meaning: A Network Meta Analysis Mapping Comparative Efficacy of Psychedelic Assisted Therapies in Modern Psychiatry

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1192/bjo.2026.11141

BJPsych Open 2026-06-01 Gaurav Uppal, Naima Gul, Asha Dhandapani, Sathyan Soundararajan, Khushboo Kansal

OpenAlex Published psilocybin Addiction Aging Clinical Trial Randomized Controlled Trial More

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Psychedelic Therapy and the Role of Music: A Scoping Review of Quantitative Evidence on Subjective and Objective Outcomes.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1002/brb3.71533 PubMed 42348297

Brain and behavior 2026-06-01 Rowe T, Hurzeler T, Towers E, Louie E, Morley KC

PubMed Published psilocybin Brain Imaging Mechanism of Action Aging Systematic Review More

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Transient multidomain functional improvement in advanced Alzheimer’s disease following high-dose psilocybin-containing mushroom administration: a case report

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.3389/fnins.2026.1813281 PubMed 42292331

Frontiers in Neuroscience 2026-05-28 Lago Marcos, Cerveira Mariana, Simonet Joe Xavier

Crossref Published psilocybin Neuroplasticity Mechanism of Action Emotional Processing Clinical Trial More

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Environmental and Internal Gating of Memory: ARCH Multiplicative Threshold Framework for Encoding and Retrieval

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.20944/preprints202605.1558.v1

Preprints.org 2026-05-26 Rahman T.

Europe PMC PREPRINT (not peer reviewed) psilocybin Drug Interactions Other More

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The magic of mushrooms: psilocybin influences behavior in the mangrove rivulus fish, Kryptolebias marmoratus

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.3389/fnbeh.2026.1767175 PubMed 42182826

Frontiers in Behavioral Neuroscience 2026-05-07 Forsyth Dayna, Faraone Nicoletta, Lamarre Simon G., Currie Suzanne

Crossref Published psilocybin Mechanism of Action Safety Drug Interactions Other More

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Trends in first-time psychedelic and other hallucinogen use in the United States: Results from the National Survey on Drug Use and Health.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1016/j.drugalcdep.2026.113059 PubMed 41795251

Drug and alcohol dependence 2026-05-01 Montoy JCC, Wang RC, Coker AR, Anderson BT

PubMed Published psilocybin Observational Study Adolescents Drug Interactions Observational Study More

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A128-Channel Wireless Wearable Myolink (W2 Myolink): Functional Characteristics and Multidisciplinary Experiments

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.21203/rs.3.rs-9266175/v1

Research Square 2026-04-28 Zajaczkowski M, Koutsoftidis S, Sheeraz M, Barsakcioglu DY, Jia T, McGeady CA

Europe PMC PREPRINT (not peer reviewed) psilocybin Brain Imaging Drug Interactions Other More

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The Harmonious Dance: A Narrative Review on Psychedelics and Music in Therapeutic Settings.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.2174/011570159x442471260422110855 PubMed 42083530

Current neuropharmacology 2026-04-28 Wang H, Li X, Yu F, Wang X

PubMed Published psilocybin Depression Anxiety PTSD Review Article More

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Psychedelics and Autism Therapy: A Review of Current Research and Future Directions.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.3390/cimb48040417 PubMed 42042077

Current issues in molecular biology 2026-04-18 Gondi CS, Gnanamony M, Gondi TP, Nersesyan L, Demirkhanyan L

PubMed Published psilocybin Depression PTSD Neuroplasticity Clinical Trial More

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Psilocybin in Older Adults: Therapeutic Opportunities in Inflammation-Driven Disorders of Aging-From Depression to Neurodegeneration

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.20944/preprints202604.1125.v1

Preprints.org 2026-04-15 Jóźwiak-Bębenista M, Stasiak A, Sienkiewicz M, Kwiatkowski P, Kowalczyk E.

Europe PMC PREPRINT (not peer reviewed) psilocybin psilocin Depression Pharmacology Mechanism of Action Review Article More

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Therapeutic Potential of Classical Psychedelics and NonHallucinogenic Psychoplastogens in Psychiatric Disorders

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.65801/pcp.3512

Psychiatry and Clinical Psychopharmacology 2026-03-30 Kenji Hashimoto, Feyza Arıcıoğlu, Mesut Çetin

OpenAlex Published psilocybin Depression Addiction Neuroplasticity Randomized Controlled Trial More

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Beyond the Genomic Storm: Evaluating Tabernanthalog as a Potential Scaffold for Silent Neuroplasticity and Broad-Spectrum Therapy.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.3390/ijms27062811 PubMed 41898671

International journal of molecular sciences 2026-03-20 Anchesi I, Raffaele I, Astorino MF, Lui M, Calabrò M, Cipriano GL

PubMed Published psilocybin End-of-Life Distress Chronic Pain Neuroplasticity Review Article More

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A fungus among us: investigating queensland’s largest magic mushroom growing operation

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1080/00450618.2026.2617320

Australian Journal of Forensic Sciences 2026-03-16 Kate Brough, Corinna Lange

OpenAlex Published psilocybin psilocin Drug Interactions Other More

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Differential Effects of Acute and Chronic Fluoxetine on Psychedelic-Induced Behavior in Mice: Implications for Clinical Trials.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1021/acsptsci.5c00484 PubMed 41852641

ACS pharmacology & translational science 2026-03-13 Wood BJ, Vest MF, Carfagno C, Bartley KR, Sharma P, Halberstadt AL

PubMed Published psilocybin Anxiety Mechanism of Action Receptor Pharmacology Clinical Trial More

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Substance-induced manic psychosis in which delusions were corroborated by a chatbot - case report

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.21203/rs.3.rs-8919841/v1

Research Square 2026-03-08 Shah S, Morrin H.

Europe PMC PREPRINT (not peer reviewed) psilocybin Addiction Spirituality Case Report Case Report More

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Safety and Efficacy of Monoamine Oxidase Inhibitors in Patients Who Use Psychoactive Substances: Potential Drug Interactions and Substance Use Disorder Treatment Data.

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Details DOI 10.1007/s40263-025-01256-7 PubMed 41546846

CNS drugs 2026-03-01 Rached G, Campana A, Fiani D, Nguyen C, Van den Eynde V, Gillman PK

PubMed Published psilocybin Depression Addiction Pharmacology Review Article More

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Psilocin as a Broad Inhibitor of CYP450 Enzymes: Integrated In Vitro and In Silico Evidence

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.26537/prpaeh.v4i3.7159

Instituto Politécnico do Porto 2026-02-25 Diana Silva, Andreia Machado Brito-da-Costa, Mariana Carvalho, Ricardo Jorge Dinis-Oliveira, Áurea Madureira-Carvalho, Sérgio F. Sousa

OpenAlex Published psilocybin psilocin Neuroplasticity Pharmacology In Vitro Study In Vitro Study More

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Effects of Psilocybin and Select Pharmaceutical Interactions

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Details DOI 10.31542/bcek6t76

MacEwan University Student eJournal 2026-02-18 Jordan McDowell, Jada Middleton, Alanna Bluett, Alisa Kozachenko, Bayan Attar, Yuvraj Singh Saini

OpenAlex Published psilocybin Depression Anxiety Pharmacology Clinical Trial More

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Network pharmacology and molecular simulation reveal the entourage effect mechanisms of psilocybin-producing mushrooms on the brain.

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Details DOI 10.1038/s41598-026-39483-7 PubMed 41691031

Scientific reports 2026-02-14 Murray Z, Lewies A, Wentzel JF, Schutte-Smith M, Erasmus E, Noreljaleel A

PubMed Published psilocybin psilocin Pharmacology Mechanism of Action Receptor Pharmacology Other More

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Development and assessment of a psychedelic-assisted therapy music playlist for clinical trials: Theory, intentionality, and metrics

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1556/2054.2026.00462

Journal of Psychedelic Studies 2026-02-12 Rafael Lancelotta, Paul Nagib, Stacey B. Armstrong, Adam W. Levin, A. B. Davis

OpenAlex Published psilocybin Chronic Pain Emotional Processing Clinical Trial Clinical Trial More