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Psilocybin and psilocin research index

Find psilocybin and psilocin papers, preprints, trials, and citations with clear source context.

Searches titles, authors, journals, identifiers, indexed metadata, and derived research topics. Use Filters to narrow by source, status, substance, study type, or date.

Database 4,961 indexed records Auto-updated on Aug 19, 2026 01:24 UTC

Executed search Study type: Review Article 470 matching records are displayed.

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Database

4,742 Psilocybin Records 673 Psilocin Records 1,461 Journals 66 Research Topics

Published 4,223 Peer-reviewed / formal records Preprints 435 Marked as not peer reviewed Clinical trials 300 ClinicalTrials.gov records R toolkit visNetwork Bibliometrics, live SQLite analysis, HTML graph, and PDF export

Top journals 1,461 indexed journals

Journal	Records
Journal of psychopharmacology (Oxford, England)	148
Journal of psychoactive drugs	97
Frontiers in psychiatry	90
Psychopharmacology	85
Neuroscience Applied	57
Journal of Psychedelic Studies	48
Psychedelic medicine (New Rochelle, N.Y.)	39
Scientific reports	37
Biological Psychiatry	32
Journal of affective disorders	32

Research topics 66 topic filters

Depression 1,737 Receptor Pharmacology 1,281 Safety 1,203 Mechanism of Action 1,072 Review Article 1,072 Clinical Trial 977 Anxiety 883 Addiction 824 Pharmacology 752 General 538 Aging 524 Animal Study 524 Observational Study 515 Brain Imaging 481 Treatment-Resistant Depression 417 Emotional Processing 409 PTSD 400 Neuroplasticity 399

Source coverage 8 active sources

Source	Count	Share	Status
PubMed	2,566	51.7%	Active
OpenAlex	1,155	23.3%	Active
Crossref	405	8.2%	Active
ClinicalTrials.gov	300	6%	Active
Europe PMC	188	3.8%	Active
PsyArXiv	186	3.7%	Active
bioRxiv	123	2.5%	Active

Publication timeline 3,858 dated records

3,858 records since 2020

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Keyword search Author

Substances Psilocybin 4742 Psilocin 673

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Executed search Study type: Review Article 470 matching records are displayed.

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470 matching records for Study type: Review Article.

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Safety and Efficacy of Monoamine Oxidase Inhibitors in Patients Who Use Psychoactive Substances: Potential Drug Interactions and Substance Use Disorder Treatment Data.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1007/s40263-025-01256-7 PubMed 41546846

CNS drugs 2026-03-01 Rached G, Campana A, Fiani D, Nguyen C, Van den Eynde V, Gillman PK

PubMed Published psilocybin Depression Addiction Pharmacology Review Article More

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Self-medication with psychedelics: a scoping review and narrative synthesis of review-level evidence.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1016/j.rcsop.2026.100709 PubMed 41674667

Exploratory research in clinical and social pharmacy 2026-03-01 Shiju S, Tirumala R, Marseille E

PubMed Published psilocybin Chronic Pain Headache / Migraine Microdosing Review Article More

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Pharmacological regulation of adult brain neuroplasticity: Synergistic roles of neuropeptide signaling, psychedelics, and synaptic modulators.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1016/j.mcn.2026.104076 PubMed 41763341

Molecular and cellular neurosciences 2026-03-01 Shokr MM, Fawzy MN, Abdelaziz AM

PubMed Published psilocybin Neuroplasticity Pharmacology Mechanism of Action Review Article More

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SSRIs, Psilocybin, MDMA, and Disease Modeling: Strategies to Advance PTSD Treatment

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.14293/pr2199.003034.v1

ScienceOpen Preprints 2026-02-24 Ishii M, Zervas M.

Europe PMC PREPRINT (not peer reviewed) psilocybin PTSD Receptor Pharmacology Review Article Review Article More

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Management of obsessive-compulsive disorder in adults.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1136/bmj-2024-083443 PubMed 41698714

BMJ (Clinical research ed.) 2026-02-16 Abramowitz JS, Abramovitch A, McKay D, Draffin A

PubMed Published psilocybin OCD Personality Change Review Article Review Article More

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Ischemia-Induced Neurodegeneration in Glaucoma: Mechanistic Insights and Translational Opportunities for Psychoplastogen-Based Therapies.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.3390/ph19020316 PubMed 41754856

Pharmaceuticals (Basel, Switzerland) 2026-02-14 Dolenec P, Pelčić G, Pilipović K, Mršić-Pelčić J, Hrkać AH

PubMed Published psilocybin Neuroplasticity Mechanism of Action Oxidative Stress Review Article More

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Activity-Dependent Neural Rewiring: Mechanisms of Psilocybin-Induced Cortical Network Reorganization

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.5281/zenodo.18501568

Zenodo (CERN European Organization for Nuclear Research) 2026-02-06 Zen Revista

OpenAlex Published psilocybin Chronic Pain Neuroplasticity Brain Imaging Review Article More

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Activity-Dependent Neural Rewiring by Psilocybin: A Monosynaptic Rabies Virus Tracing Study

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.5281/zenodo.18501514

Zenodo (CERN European Organization for Nuclear Research) 2026-02-06 Zen Revista

OpenAlex Published psilocybin Depression Chronic Pain Neuroplasticity Review Article More

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Effects of cannabis and psychedelic use on cognitive, psychomotor, and driving performance: A review of recent literature

No abstract availability was recorded for this entry.

Details DOI 10.1016/j.cotox.2026.100574

Current Opinion in Toxicology 2026-02-06 Alexa Camarena-Michel, John Michael Rague

OpenAlex Published psilocybin Review Article Toxicity Review Article More

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Placebo Effects in the Treatment of Depression-Implications for the Psychedelic Renaissance.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1016/j.ncl.2025.08.009 PubMed 41232997

Neurologic clinics 2026-02-01 Ansari M, Elliott SI, Holmes SE, Sanacora G

PubMed Published psilocybin Depression PTSD Mechanism of Action Review Article More

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We Licked the Toads so You Don't Have to: A Comprehensive Analysis of the Chemical Syntheses of the Classical Psychedelics Bufotenin(e) and 5-Methoxy-N,N-Dimethyltryptamine.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1002/cmdc.202500525 PubMed 41765690

ChemMedChem 2026-02-01 Homon A, Laramie J, Hayward JJ, Trant JF

PubMed Published psilocin Receptor Pharmacology Review Article Animal Study Review Article More

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Psychedelic research and sexuality: opportunities and pitfalls

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1093/jsxmed/qdag025 PubMed 41722098

The Journal of Sexual Medicine 2026-01-28 H. Knegtering, Thalia Herder, Nynke Boonstra, S. K. Spoelstra

OpenAlex Published psilocybin Depression PTSD Addiction Review Article More

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Mind the gap! Addressing unresolved aspects of abuse potential evaluation and scheduling of classic and novel psychedelic drugs.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1177/02698811251382147 PubMed 41099474

Journal of psychopharmacology (Oxford, England) 2026-01-01 Heal DJ, Gosden J, Smith SL

PubMed Published psilocybin Pharmacology Mechanism of Action Receptor Pharmacology Review Article More

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Contextualizing Violence Risk Associated With Hallucinogens.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1176/appi.focus.20250027 PubMed 41953889

Focus (American Psychiatric Publishing) 2026-01-01 Durns T, Iannuzzi G

PubMed Published psilocybin Review Article Safety Review Article More

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The Use of Psilocybin in the Treatment of Depressive Disorders: A Narrative Review.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.7759/cureus.102694 PubMed 41777966

Cureus 2026-01-01 Siwek L, Nowocien M, Balajewicz B, Samborska A, Szukalska S, Karczewska M

PubMed Published psilocybin Depression Anxiety Receptor Pharmacology Review Article More

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Psychedelic therapy and postpartum depression: priorities and prospects.

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1177/20451253251408280 PubMed 41816502

Therapeutic advances in psychopharmacology 2026-01-01 Thuery G, Crossen F, Mc Loone D, Hinds C, Duffy R, Jairaj C

PubMed Published psilocybin Depression Mechanism of Action Aging Review Article More

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Psychedelics and neuroanesthesia: A narrative review of converging mechanisms

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.65929/jsia.2026.1.2.002

Journal of Scientific Innovations in Anesthesiology 2025-12-31 Kunal Kumar Sharma

OpenAlex Published psilocybin Depression Anxiety PTSD Review Article More

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Which Psychotherapy Model Should be Used in Psilocybin Treatment for Depression?

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.47626/2237-6089-2025-1197 PubMed 41405984

Trends in psychiatry and psychotherapy 2025-12-17 Koning E, Bacchi P, Chaves C, Gomes FA, Brietzke E

PubMed Published psilocybin Depression Psychological Flexibility Review Article Review Article More

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Psilocybin and MDMA in Couples Therapy: Investigating Treatment for Substance Use Disorders and Codependency

Abstract available at the source but not redistributed here. Read at source.

Details DOI 10.1007/s10591-025-09766-8

Contemporary Family Therapy 2025-12-11 Samuel Hosford, Heather Austin-Robillard

OpenAlex Published psilocybin PTSD Addiction Aging Review Article More

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Psychedelics as neuroplasticity enhancers: Mechanisms, therapeutic applications, and translational challenges

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Details DOI 10.36922/an025410095

Advanced Neurology 2025-12-04 Taslim Uddin, Suma Akter, Kanak Yadab Ghosh

OpenAlex Published psilocybin Depression PTSD Addiction Review Article More