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Psychedelics: Alternative and Potential Therapeutic Options for Treating Mood and Anxiety Disorders.

Molecules (Basel, Switzerland) 2022-04-14 Lowe H, Toyang N, Steele B, Grant J, Ali A, Gordon L DOI 10.3390/molecules27082520

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Depression Anxiety Addiction Review Article All topics and provenance

Will psilocybin lose its magic in the clinical setting?

Therapeutic advances in psychopharmacology 2022-01-01 Hayes C, Wahba M, Watson S DOI 10.1177/20451253221090822

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Depression Review Article Healthcare Workers Clinical Trial All topics and provenance

The Pharmacology and Clinical Applications of Psychedelic Medicines Within Midwifery Practice.

Journal of midwifery & women's health 2022-05-01 Stein CA, Penn A, Van Hope S, Dorsen CG, Mangini M DOI 10.1111/jmwh.13371

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Depression PTSD Pharmacology Review Article All topics and provenance

The psychological processes of classic psychedelics in the treatment of depression: a systematic review protocol.

Systematic reviews 2022-05-05 Johansen L, Liknaitzky P, Nedeljkovic M, Mastin-Purcell L, Murray G DOI 10.1186/s13643-022-01930-7

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Depression Systematic Review Review Article Systematic Review All topics and provenance

New Paradigms of Old Psychedelics in Schizophrenia.

Pharmaceuticals (Basel, Switzerland) 2022-05-23 Mahmood D, Alenezi SK, Anwar MJ, Azam F, Qureshi KA, Jaremko M DOI 10.3390/ph15050640

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Depression Anxiety PTSD Other All topics and provenance

Unraveling the Mysteries of Mental Illness With Psilocybin.

Cureus 2022-05-01 Sotille R, Singh H, Weisman A, Vida T DOI 10.7759/cureus.25414

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Depression Neuroplasticity Receptor Pharmacology Clinical Trial All topics and provenance

Psychedelic perceptions: mental health service user attitudes to psilocybin therapy.

Irish journal of medical science 2022-06-01 Corrigan K, Haran M, McCandliss C, McManus R, Cleary S, Trant R DOI 10.1007/s11845-021-02668-2

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Depression Anxiety Observational Study Observational Study All topics and provenance

Assessing the risk-benefit profile of classical psychedelics: a clinical review of second-wave psychedelic research.

Psychopharmacology 2022-06-01 Bender D, Hellerstein DJ DOI 10.1007/s00213-021-06049-6

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Depression Brain Imaging Aging Clinical Trial All topics and provenance

Psychedelic-assisted psychotherapy for the treatment of major depression: a synthesis of phenomenological explanations.

Medicine, health care, and philosophy 2022-06-01 Miceli McMillan R, Jordens C DOI 10.1007/s11019-022-10070-7

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Depression Other All topics and provenance

The therapeutic potential of psilocybin: a systematic review.

Expert opinion on drug safety 2022-06-01 van Amsterdam J, van den Brink W DOI 10.1080/14740338.2022.2047929

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Depression Anxiety Clinical Trial Randomized Controlled Trial All topics and provenance

Effects of the 5-HT receptor antagonist volinanserin on head-twitch response and intracranial self-stimulation depression induced by different structural classes of psychedelics in rodents.

Psychopharmacology 2022-06-01 Jaster AM, Elder H, Marsh SA, de la Fuente Revenga M, Negus SS, González-Maeso J DOI 10.1007/s00213-022-06092-x

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Depression Addiction Pharmacology Animal Study All topics and provenance

Drug-drug interactions between psychiatric medications and MDMA or psilocybin: a systematic review.

Psychopharmacology 2022-06-01 Sarparast A, Thomas K, Malcolm B, Stauffer CS DOI 10.1007/s00213-022-06083-y

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Depression PTSD Pharmacology Randomized Controlled Trial All topics and provenance

The promises and perils of psychedelic pharmacology for psychiatry.

Nature reviews. Drug discovery 2022-06-01 McClure-Begley TD, Roth BL DOI 10.1038/s41573-022-00421-7

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Depression Anxiety Pharmacology Clinical Trial All topics and provenance

Development of an -based norbaeocystin production platform and evaluation of behavioral effects in rats.

Metabolic engineering communications 2022-06-01 Adams AM, Anas NA, Sen AK, Hinegardner-Hendricks JD, O'Dell PJ, Gibbons WJ DOI 10.1016/j.mec.2022.e00196

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Depression Mechanism of Action Receptor Pharmacology Other All topics and provenance

How to account for hallucinations in the interpretation of the antidepressant effects of psychedelics: a translational framework.

Psychopharmacology 2022-06-01 van den Berg M, Magaraggia I, Schreiber R, Hillhouse TM, Porter JH DOI 10.1007/s00213-022-06106-8

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Depression Pharmacology Mystical Experience Other All topics and provenance

Safety issues of psilocybin and LSD as potential rapid acting antidepressants and potential challenges.

Expert opinion on drug safety 2022-06-01 Rossi GN, Hallak JEC, Bouso Saiz JC, Dos Santos RG DOI 10.1080/14740338.2022.2066650

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Depression Mechanism of Action Clinical Trial Randomized Controlled Trial All topics and provenance

Psilocybin: A brief overview for psychiatric mental health nurse practitioners.

Perspectives in psychiatric care 2022-07-01 Fradkin D DOI 10.1111/ppc.12888

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Depression Anxiety Addiction Other All topics and provenance

From psychiatry to neurology: Psychedelics as prospective therapeutics for neurodegenerative disorders.

Journal of neurochemistry 2022-07-01 Kozlowska U, Nichols C, Wiatr K, Figiel M DOI 10.1111/jnc.15509

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Depression Addiction Neuroplasticity Clinical Trial All topics and provenance

Molecular insights into psychedelic drug action.

Journal of neurochemistry 2022-07-01 Slocum ST, DiBerto JF, Roth BL DOI 10.1111/jnc.15540

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Depression Mechanism of Action Receptor Pharmacology Review Article All topics and provenance

Psychedelic-inspired approaches for treating neurodegenerative disorders.

Journal of neurochemistry 2022-07-01 Saeger HN, Olson DE DOI 10.1111/jnc.15544

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Depression PTSD Addiction Other All topics and provenance

Research guides and tools

Database details

4,922 Psilocybin records 695 Psilocin records 1,492 Journal labels 66 Research topics

Published 4,370 Published / formal records Preprints 460 Marked as not peer reviewed Clinical trial registrations 310 ClinicalTrials.gov records Protocols 3 Study protocol records

Substance categories overlap; their counts must not be summed. Journal labels exclude preprint and trial-registry venues and may include name variants. Research topics are derived screening categories. Publication status does not independently verify peer review.

Publication timeline

4,041 records since 2020

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Top journals 1,492 indexed journals

Journal	Records
Journal of psychopharmacology (Oxford, England)	154
Journal of psychoactive drugs	100
Frontiers in psychiatry	93
Psychopharmacology	91
Neuroscience Applied	57
Journal of Psychedelic Studies	49
Psychedelic medicine (New Rochelle, N.Y.)	39
Scientific reports	37
Journal of affective disorders	34
Psychiatric News	33

Research topics 66 topic filters

Depression 1,812 Receptor Pharmacology 1,312 Safety 1,267 Mechanism of Action 1,122 Review Article 1,121 Clinical Trial 1,030 Anxiety 921 Addiction 848 Pharmacology 776 Animal Study 551 General 548 Observational Study 541 Aging 539 Brain Imaging 494 Treatment-Resistant Depression 441 Emotional Processing 426 Neuroplasticity 422 PTSD 411

Source coverage 8 active sources

Source	Count	Share	Status
PubMed	2,589	50.3%	Active
OpenAlex	1,190	23.1%	Active
Crossref	431	8.4%	Active
ClinicalTrials.gov	310	6%	Active
Europe PMC	260	5.1%	Active
PsyArXiv	188	3.7%	Active
bioRxiv	130	2.5%	Active

Psilocybin research database

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