The Theoretical Description for Psilocin Electrochemical Determination over Cobalt Oxyhydroxide

The possibility of psilocin electrochemical determination over cobalt (III) oxyhydroxide-modified anode is evaluated from the mathematical point of view. Psilocin is thereby oxidized yielding either micro- or macromolecular product, being both of them important for the economical and green conducting polymer composite for electrocatalysis, electroanalysis an...

Conformational Landscape and Hydrogen Bonding Pattern of Psilocin: Computational Insights

Abstract Conformational analysis of psilocin, a psychedelic molecule was carried out at B3LYP/cc-pVTZ level of theory. And a global minimum was identified having highest population among all the local conformers along with second stable conformer which is 5.4 kcal/mol higher in energy than global minimum. The global mimimum is stable due to the formation of ...

Electrophysiological study of visual and auditory processing in psilocin-induced hallucinations: exploring evoked potentials and 5-HT2A receptor involvement

Direct Quantitation of Psilocybin and Psilocin by One-Dimensional 1H and 31P qNMR in a revived Greek specimen of Psilocybe cyanescens

P03-18 Simultaneous detection and quantification of psilocybin and psilocin by gas chromatography coupled to mass spectrometry (GC-MS)

Production and extraction of psilocybin and psilocin from Psilocybe spp. mushrooms

Evaluation of a quantitative analytical method for psilocin and psilocybin using HPLC-DAD

Psylocybin and Psilocin as new tools to fight depression: an overview of the Pharmacodynamic and pharmacokinetic mechanisms

Rats hallucinate in a similar manner to humans after psilocin

Unravelling a New Conformer of Psilocin Through Computational Methods

P.0553 Effect of chronic microdosing of psilocin on cell proliferation and behavior in rats

P.0858 Psilocin induces perceptual alterations in rats: visual discrimination study

Sensitive quantitative analysis of psilocin and psilocybin in hair samples from suspected users and their distribution in seized hallucinogenic mushrooms

Abstract Purpose In this study, we developed a very sensitive method for quantitative analysis of psilocin and psilocybin in hair samples of magic mushroom consumers. Methods The analyses were performed with pretreatments of samples, followed by ultra-high pressure liquid chromatography (LC) connected to a Q-Trap type tandem mass spectrometry (MS/MS). For LC...

Effects of the putative antidepressant psilocin on the lipid-raft proteome and lipid-raft signaling

Serotonergic hallucinogens psilocybin, and its active metabolite psilocin, have shown promise as rapid-acting antidepressants. The FDA granted breakthrough therapy designation for psilocybin's use as an antidepressant in 2019, and phase II clinical trials are currently ongoing. Psilocybin is converted to psilocin following oral administration, and this metab...

ChemInform Abstract: Observations Concerning the Synthesis of Tryptamine Homologues and Branched Tryptamine Derivatives via the Borrowing Hydrogen Process: Synthesis of Psilocin, Bufotenin, and Serotonin.

AbstractThe selective indole alkylation reaction applying the Ir-catalyzed-borrowing hydrogen methodology and using amino alcohols (II), (V), (VII) as suitable nitrogen-containing electrophiles is reported.

Observations concerning the synthesis of tryptamine homologues and branched tryptamine derivatives via the borrowing hydrogen process: synthesis of psilocin, bufotenin, and serotonin

HPLC Analysis of Hallucinogenic Mushroom Alkaloids (Psilocin and Psilocybin) Applying Hydrophilic Interaction Chromatography (HILIC)

Taxonomic Identification of Hallucinogenic Mushrooms Seized on the Illegal Market Using a DNA-Based Approach and LC/MS-MS Determination of Psilocybin and Psilocin

14C-Psilocin tissue distribution in pregnant rats after intravenous administration

Background: Many species of hallucinogenic mushrooms have been found in the genus Psilocybe. The main psychoactive chemicals of Psilocybe mushrooms are psilocin and its phosphoryloxy derivative, psilocybin. In addition to its psychedelic effects, psilocybin is an effective agent to lift the mood of depressed patients with terminal cancers.Objective: To study...

P.4.022 The impact of serotonin system modulation on behavior and quantitative EEG in an animal model of psychosis induced by psilocin