Researcher index
Authors in the psilocybin and psilocin literature
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Publication history
Psilocybin as serotonergic therapy in epilepsy: Narrative review of potentials and limitations.British journal of clinical pharmacology · 2026-10-01Psilocybin for Chronic Pelvic Pain (CPP) in Women: A Pilot Feasibility StudyClinicalTrials.gov · 2026-09-23Surrender, disidentification, and reappraisal: a qualitative comparison of psilocybin responders and non-responders in treatment-resistant OCDFrontiers in psychiatry · 2026-09-16Who Is Reached by Supervised Psilocybin Services? Oregon Services Versus National Psilocybin UsemedRxiv · 2026-09-07One dose of Psilocybin modulates Brain Activity among Depressive patients: Preliminary Neuroimaging Results from the PSILODAC StudyEuropean psychiatry: the journal of the Association of European Psychiatrists · 2026-09-04Assessing The Readiness of Psychiatrists in Louisiana to Incorporate Psilocybin into Clinical Practice-Lessons Learned from a State Underrepresented in Clinical Psychedelic Research.Psychedelic medicine (New Rochelle, N.Y.) · 2026-09-01Balancing safety and access in Oregon's psilocybin services.The International journal on drug policy · 2026-09-01Complex Fatal Self-Harm Under Psilocybin Intoxication: Suicidal Manner of Death or Not?Academic forensic pathology · 2026-08-21Feasibility and Tolerability of Psilocybin for Phantom Limb Pain.The journal of pain · 2026-08-07Psilocybin-assisted therapy for treatment-resistant major depressive disorder in a public healthcare setting: a randomized controlled trial.Nature medicine · 2026-08-06Single Dose Psilocybin for a Post-surgical Trauma Inpatient Population for Pain, Mood, and Opioid Use DisorderClinicalTrials.gov · 2026-08-06Psilocybin as a Treatment for Chronic Pain in SmokersClinicalTrials.gov · 2026-08-03The Experience-Trajectory Framework: Substance-Specific Risk Stratification for Psychedelic Preparation and Aftercare Beyond Set and SettingInternational Journal For Multidisciplinary Research · 2026-07-31Beyond psilocybin: Do magic mushroom preparations contain other compounds with pharmacological effects?Authorea Preprints · 2026-07-30Treatment With Psilocybin for Chronic Neuropathic Pain and Depression (TRANSCEND): An Open-Label Clinical TrialClinicalTrials.gov · 2026-07-30Psilocybin-Assisted Early Palliative Care for Demoralization and Chronic Pain: An Open-Label Pilot Study.medRxiv: the preprint server for health sciences · 2026-07-14Computationally, Electrophysiologically, and Qualitatively Characterizing Serotonergic Psychedelics; Transdiagnostic Therapeutic and Pro-Psychotic EffectsClinicalTrials.gov · 2026-07-09The relevance of the 5HT2A-mGlu2 heterodimer in explaining the clinical ambivalence of psilocybinRevista de Neuro-Psiquiatría · 2026-06-30Psilocybin-Assisted Massed Cognitive Processing Therapy for Chronic Posttraumatic Stress Disorder: An Open-label TrialClinicalTrials.gov · 2026-06-26Beyond Psychedelic Microdosing: Therapeutic Potential, Neuropharmacology, and Safety Considerations in Low-Dose Psychoactive UseJournal of Advances in Developmental Research · 2026-06-17Patient perceptions towards psychedelics for musculoskeletal pain: A cross-sectional surveymedRxiv · 2026-06-01Mapping cognitive-behavioral approach in psychedelic-assisted treatment: a systematic review across phases with classic and non-classic psychedelics.European archives of psychiatry and clinical neuroscience · 2026-06-01Global increases in brain glucose metabolism following acute N,N-dimethyltryptamine and harmine administration in healthy volunteers: A randomised [F]FDG-PET study.Journal of cerebral blood flow and metabolism: official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026-06-01Hallucinogen-Assisted Psychotherapy for Trauma Disorders: A Bionian Lens.Psychodynamic psychiatry · 2026-06-01Expectations and Motivations for Participation in Clinical Trials Utilizing Psychedelics for Treatment-Resistant Depression: A Qualitative Study.Brain and behavior · 2026-06-01Therapeutic advances in fibromyalgia: one year in review 2026.Clinical and experimental rheumatology · 2026-06-01PsiConnect: Multimodal Neuroimaging of Context-Dependent Brain and Behaviour Dynamics under PsilocybinScientific Data · 2026-05-21Insights into psilocybin use among people with bipolar disorder: A thematic analysis of Reddit postsJournal of Affective Disorders · 2026-05-01Age moderates the relationship between psychedelics use and mental health in naturalistic settingsResearch Square · 2026-03-10Enhancing cGMP signaling with psilocybin reduces head twitch and restructures the synaptic proteome while maintaining antidepressant responsebioRxiv · 2026-03-10Ischemia-Induced Neurodegeneration in Glaucoma: Mechanistic Insights and Translational Opportunities for Psychoplastogen-Based Therapies.Pharmaceuticals (Basel, Switzerland) · 2026-02-14Difficulties following naturalistic psychedelic use and associations with adverse childhood experiences.The International journal on drug policy · 2026-02-01Psychedelic Modulation of Excitation/Inhibition Balance: A Dual-Phase Neurodevelopmental Model.ACS chemical neuroscience · 2026-01-21Psychological Therapy Quantity and Depressive Symptom Reduction in Psychedelic-Assisted Therapy: A Systematic Review and Meta-Analysis.JAMA network open · 2026-01-025 Years of bipolar disorder conversations on Reddit: Methods, key topics and future directions.PloS one · 2026-01-01Psychedelic-assisted therapy: a survey on the clinical methods of Swiss physicians.Therapeutic advances in psychopharmacology · 2026-01-01Psilocybin as a Serotonergic Therapy in Epilepsy: Narrative Review of Therapeutic Potentials and Seizure RisksAuthorea Preprints · 2025-12-29A Naturalistic Study on the Combined Neural and Psychological Effects of Psilocybin and Compassion Focused ImagerybioRxiv · 2025-12-22Standardized Natural Psilocybin-assisted Psychotherapy for Tapering of Opioid Medication in Patients With Chronic Pain: an Open-label Feasibility StudyClinicalTrials.gov · 2025-12-04Avoiding Stigma and Sensationalism in Therapeutic Psilocybin Communications: Considerations for Reaching Older Patients.The American journal of geriatric psychiatry: official journal of the American Association for Geriatric Psychiatry · 2025-12-01Correction: Synergistic, multi-level understanding of psychedelics: three systematic reviews and meta-analyses of their pharmacology, neuroimaging and phenomenologyTranslational Psychiatry · 2025-11-12Endocannabinoids, depression, and treatment resistance: Perspectives on effective therapeutic interventions.Psychiatry research · 2025-10-01Ethical issues with psychedelic-assisted treatments in psychiatry: A systematic scoping review.Psychological medicine · 2025-09-29A critical evaluation of psilocybin-assisted therapy protocol components from clinical trial patients, facilitators, and caregivers.Psychotherapy (Chicago, Ill.) · 2025-09-01Unequal representation? A cross-sectional analysis of age, sex, race, and ethnicity in clinical trials of classic psychedelics.Journal of psychopharmacology (Oxford, England) · 2025-09-01Psilocybin treatment for symptoms of depression: a living systematic review, meta-analysis, and data resourcemedRxiv · 2025-08-16Perspectives on Trauma Treatment, Self-Management Strategies, and Attitudes Toward Psychedelic Therapies in Individuals with Psychological Trauma Symptoms.Psychiatry and clinical psychopharmacology · 2025-07-30Global Increases in Brain Glucose Metabolism Following Acute N,N-Dimethyltryptamine and Harmine Administration in Healthy Volunteers: An [¹⁸F]FDG-PET StudyResearch Square · 2025-07-27Rise of the Mushrooms: Effects of Psilocybin Reforms on Psychedelic Usage PatternsJournal of Public Policy & Marketing · 2025-07-16Behavioural and pharmacological evaluation of the psilocybin analogue baeocystin in Wistar rats.Progress in neuro-psychopharmacology & biological psychiatry · 2025-07-13Psilocybin With Intracranial Neural SensingClinicalTrials.gov · 2025-06-06The Potential Role of Psilocybin in Traumatic Brain Injury Recovery: A Narrative Review.Brain sciences · 2025-05-26Psilocybin-induced modulation of visual salience processingbioRxiv · 2025-05-12Psilocybin for disorders of consciousness: A case-report study.Clinical neurophysiology: official journal of the International Federation of Clinical Neurophysiology · 2025-05-01Divergent Effects of Psilocybin for 2 Patients Participating in a Psilocybin-assisted Cognitive Behavioral Therapy Trial for Major Depressive Disorder.Journal of psychiatric practice · 2025-05-01A Phase 2a, Open-label, Pilot Study to Assess the Safety and Efficacy of Psilocybin Administration in Concert With Psychotherapy Among Adult Patients With FibromyalgiaClinicalTrials.gov · 2025-04-1658. Acute Behavioral Effects of Psilocybin and Its Pharmacokinetics in Nonhuman PrimatesBiological Psychiatry · 2025-04-09A Rapid Review of Psychedelic-Assisted Therapy in the Context of Palliative Care.Journal of hospice and palliative nursing: JHPN: the official journal of the Hospice and Palliative Nurses Association · 2025-04-01A Rapid Review of Psychedelic-Assisted Therapy in the Context of Palliative Care.Journal of hospice and palliative nursing: JHPN: the official journal of the Hospice and Palliative Nurses Association · 2025-04-01Psilocybin for Enhanced Analgesia in Chronic nEuropathic PAINClinicalTrials.gov · 2025-03-30Current U.S. Approaches to Studying Psychedelic Medicines Compared to Psychedelics Use Among Indigenous Groups: What Are We Missing?Journal of Humanistic Psychology · 2025-03-21Prolonged adverse effects from repeated psilocybin use in an underground psychedelic therapy training program: a case report.BMC psychiatry · 2025-02-28Australian psychologists' attitudes towards psychedelic-assisted therapy and training following a world-first drug down-scheduling.Drug and alcohol review · 2025-01-01Exploring Psychedelics Pharmacology: A Scoping Review Charting the Course of Psilocybin Pharmacokinetics.Clinical neuropharmacology · 2025-01-01Molecular brain imaging of psychedelic action.International review of neurobiology · 2025-01-01Serotonergic psychedelics for depression: A comprehensive overview.International review of neurobiology · 2025-01-01Study Protocol for 'PsilOCD: A Pharmacological Challenge Study Evaluating the Effects of the 5-HT2A Agonist Psilocybin on the Neurocognitive and Clinical Correlates of Compulsivity'.Cureus · 2025-01-01Correction: Study Protocol for 'PsilOCD: A Pharmacological Challenge Study Evaluating the Effects of the 5-HT2A Agonist Psilocybin on the Neurocognitive and Clinical Correlates of Compulsivity'.Cureus · 2025-01-01Informed Consent Documents from Psychedelic Clinical Trials: A Descriptive Ethical Analysis.AJOB empirical bioethics · 2025-01-01Acute and post-dosing effects of single-dose psilocybin for obsessive-compulsive disorder in a randomized, double-blind, placebo-controlled trial: an interpretative phenomenological analysis.Frontiers in psychiatry · 2025-01-01A virtual clinical trial of psychedelics to treat patients with disorders of consciousnessbioRxiv · 2024-08-19Ketamine-Induced Unresponsiveness Shows a Harmonic Shift from Global to Localised Functional OrganisationbioRxiv · 2024-06-25At the Forefront: Social Workers' Role in Psilocybin Treatment for Depression and Substance Misuse.Social work · 2024-06-21Mechanisms of therapeutic change after psychedelic treatment in OCD.Psychiatry research · 2024-06-01Structural pharmacology and therapeutic potential of 5-methoxytryptamines.Nature · 2024-06-01Comparing Neural Correlates of Consciousness: From Psychedelics to Hypnosis and Meditation.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2024-05-01The 'PSILAUT' protocol: an experimental medicine study of autistic differences in the function of brain serotonin targets of psilocybin.BMC psychiatry · 2024-04-25Psychedelics and sexual functioning: a mixed-methods study.Scientific reports · 2024-02-07In vivo validation of psilacetin as a prodrug yielding modestly lower peripheral psilocin exposure than psilocybinFrontiers in Psychiatry · 2024-01-08The Psychedelic Future of Post-Traumatic Stress Disorder Treatment.Current neuropharmacology · 2024-01-01Corrigendum: Safety, feasibility, tolerability, and clinical effects of repeated psilocybin dosing combined with non-directive support in the treatment of obsessive-compulsive disorder: protocol for a randomized, waitlist-controlled trial with blinded ratings.Frontiers in psychiatry · 2024-01-01Prospective Preference Assessment for the Psilocybin for Enhanced Analgesia in Chronic nEuropathic PAIN (PEACE-PAIN) Trial.Canadian journal of pain = Revue canadienne de la douleur · 2024-01-01Potential use of psilocybin drugs in the treatment of depression.Expert opinion on emerging drugs · 2023-12-01Acute effects of psilocybin on the dynamics of gaze fixations during visual aesthetic perceptionbioRxiv · 2023-11-01Expectancies for Subjective and Antidepressant Effects in Psilocybin UsersJournal of Humanistic Psychology · 2023-09-22Assessing the risk of symptom worsening in psilocybin-assisted therapy for depression: A systematic review and individual participant data meta-analysis.Psychiatry research · 2023-09-01Psychedelics, With a Focus on Psilocybin: Issues for the Clinician.Journal of psychiatric practice · 2023-09-01Repeated low doses of psilocybin increase resilience to stress, lower compulsive actions, and strengthen cortical connections to the paraventricular thalamic nucleus in rats.Molecular psychiatry · 2023-09-01Molecular mechanisms of rapid-acting antidepressants: New perspectives for developing antidepressants.Pharmacological research · 2023-08-01In vivo mapping of pharmacologically induced functional reorganization onto the human brain's neurotransmitter landscape.Science advances · 2023-06-16Yale Program for Psychedelic Science (YPPS) Manual for Psilocybin Combined with Non-Directive Support in the Treatment of OCDPsyArXiv · 2023-03-17Psychedelics for the Neuropsychiatric Symptoms of Alzheimer's diseaseAmerican Journal of Geriatric Psychiatry · 2023-02-15Functional MRI markers for treatment-resistant depression: Insights and challenges.Progress in brain research · 2023-01-01Safety, tolerability, and clinical and neural effects of single-dose psilocybin in obsessive-compulsive disorder: protocol for a randomized, double-blind, placebo-controlled, non-crossover trial.Frontiers in psychiatry · 2023-01-01Safety, feasibility, tolerability, and clinical effects of repeated psilocybin dosing combined with non-directive support in the treatment of obsessive-compulsive disorder: protocol for a randomized, waitlist-controlled trial with blinded ratings.Frontiers in psychiatry · 2023-01-01Single-dose psilocybin for treatment-resistant obsessive-compulsive disorder: A case report.Heliyon · 2022-12-01Extensive Collection of Psychotropic Mushrooms with Determination of Their Tryptamine Alkaloids.International journal of molecular sciences · 2022-11-15Structure-Activity Relationships for Psilocybin, Baeocystin, Aeruginascin, and Related Analogues to Produce Pharmacological Effects in Mice.ACS pharmacology & translational science · 2022-11-115-MeO-DMT modifies innate behaviors and promotes structural neural plasticity in micebioRxiv · 2022-11-03Yale Program for Psychedelic Science (YPPS) Manual for Psilocybin-OCD Session Monitors for Protocol HIC: 2000020355PsyArXiv · 2022-10-05Where do we go next in antidepressant drug discovery? A new generation of antidepressants: a pivotal role of AMPA receptor potentiation and mGlu2/3 receptor antagonism.Expert opinion on drug discovery · 2022-10-01Psilocybin Efficacy and Mechanisms of Action in Major Depressive Disorder: a Review.Current psychiatry reports · 2022-10-01Psilocybin Therapy for Treatment Resistant Depression: Prediction of Clinical Outcome by Natural Language ProcessingPsyArXiv · 2022-09-30Molecular Structure, Reactivity and Spectroscopic Properties of Hallucinogens Psilocybin, Mescaline and their Derivatives - A Computational StudyLetters in Applied NanoBioScience · 2022-09-17A Review of Aeruginascin and Potential Entourage Effect in Hallucinogenic MushroomsEuropean psychiatry: the journal of the Association of European Psychiatrists · 2022-09-01Natural language signatures of psilocybin microdosing.Psychopharmacology · 2022-09-01Use of psychedelics in the Czech Republic: results of recent population surveys.Central European journal of public health · 2022-09-01Examining Attitudes to Psilocybin: Should Candidates for Medical Psilocybin be Required to Pass a Contextual Suitability Test?Journal of Humanistic Psychology · 2022-08-18Microdosing with psilocybin mushrooms: a double-blind placebo-controlled study.Translational psychiatry · 2022-08-02Psilocybin reduces low frequency oscillatory power and neuronal phase-locking in the anterior cingulate cortex of awake rodents.Scientific reports · 2022-07-26Synthesis, Structural Characterization, and Pharmacological Activity of Novel Quaternary Salts of 4-Substituted Tryptamines.ACS omega · 2022-07-19Mapping Pharmacologically-induced Functional Reorganisation onto the Brain’s Neurotransmitter LandscapebioRxiv · 2022-07-13Optimization through a Box-Behnken Experimental Design of the Microwave-Assisted Extraction of the Psychoactive Compounds in Hallucinogenic Fungi ().Journal of fungi (Basel, Switzerland) · 2022-06-02Psilocybin-assisted psychotherapy for depression: Emerging research on a psychedelic compound with a rich history.Journal of the neurological sciences · 2022-03-15Natural language signatures of psilocybin microdosingbioRxiv · 2022-02-22Microevidence for microdosing with psilocybin mushrooms: a double-blind placebo-controlled study of subjective effects, behavior, creativity, perception, cognition, and brain activitybioRxiv · 2021-12-07Psilocybin, a Naturally Occurring Indoleamine Compound, Could Be Useful to Prevent Suicidal Behaviors.Pharmaceuticals (Basel, Switzerland) · 2021-11-24Adults who microdose psychedelics report health related motivations and lower levels of anxiety and depression compared to non-microdosers.Scientific reports · 2021-11-18A Complex Impact of Systemically Administered 5-HT2A Receptor Ligands on Conditioned Fear.The international journal of neuropsychopharmacology · 2021-09-21A Qualitative Exploration of Relational Ethical Challenges and Practices in Psychedelic HealingJournal of Humanistic Psychology · 2021-09-16Psychedelics and psychiatric disorders: A emerging roleEuropean psychiatry: the journal of the Association of European Psychiatrists · 2021-08-13Psychedelics as a Training Experience for Psychedelic Therapists: Drawing on History to Inform Current PracticeJournal of Humanistic Psychology · 2021-06-23Participant Reports of Mindfulness, Posttraumatic Growth, and Social Connectedness in Psilocybin-Assisted Group Therapy: An Interpretive Phenomenological AnalysisJournal of Humanistic Psychology · 2021-06-12Psychedelic-Assisted Psychotherapy Practices and Human Caring Science: Toward a Care-Informed Model of TreatmentJournal of Humanistic Psychology · 2021-04-23Molecular and Functional Imaging Studies of Psychedelic Drug Action in Animals and Humans.Molecules (Basel, Switzerland) · 2021-04-22Stability of psilocybin and its four analogs in the biomass of the psychotropic mushroom Psilocybe cubensis.Drug testing and analysis · 2021-02-01The Effects of Tryptamine Psychedelics in the Brain: A meta-Analysis of Functional and Review of Molecular Imaging Studies.Frontiers in pharmacology · 2021-01-01P300-mediated modulations in self-other processing under psychedelic psilocybin are related to connectedness and changed meaning: A window into the self-other overlap.Human brain mapping · 2020-12-01Perceived harm, motivations for use and subjective experiences of recreational psychedelic 'magic' mushroom use.Journal of psychopharmacology (Oxford, England) · 2020-09-01Scalable Hybrid Synthetic/Biocatalytic Route to Psilocybin.Chemistry (Weinheim an der Bergstrasse, Germany) · 2020-07-02Commentary: Psychedelic Psychiatry's Brave New World.Frontiers in psychiatry · 2020-01-01Serotonergic hallucinogens/psychedelics could be promising treatments for depressive and anxiety disorders in end-stage cancer.BMC psychiatry · 2019-10-28Spectral signatures of serotonergic psychedelics and glutamatergic dissociatives.NeuroImage · 2019-10-15Hallucinogens and Their Therapeutic Use: A Literature Review.Journal of psychiatric practice · 2019-09-01Pharmacological interventions targeting anhedonia in patients with major depressive disorder: A systematic review.Progress in neuro-psychopharmacology & biological psychiatry · 2019-06-08Ceremonial "plant medicine" use and its relationship to recreational drug use: an exploratory study.Addiction research & theory · 2019-01-01Biological Effects and Biodistribution of Bufotenine on Mice.BioMed research international · 2018-01-01Developing Guidelines and Competencies for the Training of Psychedelic TherapistsJournal of Humanistic Psychology · 2017-06-29Patients’ Accounts of Increased “Connectedness” and “Acceptance” After Psilocybin for Treatment-Resistant DepressionJournal of Humanistic Psychology · 2017-06-19Cancer at the Dinner Table: Experiences of Psilocybin-Assisted Psychotherapy for the Treatment of Cancer-Related DistressJournal of Humanistic Psychology · 2017-06-14Patient Experiences of Psilocybin-Assisted Psychotherapy: An Interpretative Phenomenological AnalysisJournal of Humanistic Psychology · 2017-04-28Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial.Journal of psychopharmacology (Oxford, England) · 2016-12-01The role of psychedelics in palliative care reconsidered: A case for psilocybin.Journal of psychopharmacology (Oxford, England) · 2016-12-01Development of a Psychotherapeutic Model for Psilocybin-Assisted Treatment of AlcoholismJournal of Humanistic Psychology · 2016-10-16Psychedelic Psychotherapy: Insights From 25 Years of ResearchJournal of Humanistic Psychology · 2016-09-29Psilocybin: panacea or placebo?The lancet. Psychiatry · 2016-09-01Altered states: psilocybin for treatment-resistant depression.The lancet. Psychiatry · 2016-07-01Psychedelics.Pharmacological reviews · 2016-04-01Unifying electron transfer mechanism for psilocybin and psilocinMedical Hypotheses · 2009-10-01Novel, unifying mechanism for mescaline in the central nervous system: electrochemistry, catechol redox metabolite, receptor, cell signaling and structure activity relationships.Oxidative medicine and cellular longevity · 2009-01-01Identification of a serotonin/glutamate receptor complex implicated in psychosis.Nature · 2008-03-06Hallucinogens recruit specific cortical 5-HT(2A) receptor-mediated signaling pathways to affect behavior.Neuron · 2007-02-01Patterns of simultaneous polysubstance use in drug using university students.Human psychopharmacology · 2006-06-01Using psilocybin to investigate the relationship between attention, working memory, and the serotonin 1A and 2A receptors.Journal of cognitive neuroscience · 2005-10-01[Acute higher funghi mushroom poisoning and its treatment].Presse medicale (Paris, France: 1983) · 2003-09-20Skinner, Maslow, and PsilocybinJournal of Humanistic Psychology · 1993-07-01Synthesis of psilocin labelled with 14C and 3HJournal of Labelled Compounds and Radiopharmaceuticals · 1986-02-01Molecular structures of hallucinogenic substances: lysergic acid diethylamide, psilocybin, and 2,4,5-trimethoxyamphetamine.Molecular pharmacology · 1973-01-01ChemInform Abstract: INDOLE 22. MITT. INDOLSYNTH., ANWENDUNG AUF PSILOCINChemischer Informationsdienst. Organische Chemie · 1970-12-21PSILOCYBIN-INDUCED CHANGES IN PSYCHOLOGIC FUNCTION, ELECTROENCEPHALOGRAM, AND LIGHT-EVOKED POTENTIALS IN HUMAN SUBJECTSMayo Clinic Proceedings · 1968-03-01Biosynthesis of psilocybin in submerged culture of Psilocybe cubensis. 1. Incorporation of labelled tryptophan and tryptamine.Acta pharmaceutica Suecica · 1966-02-01Drugs and phantasy: the effects of LSD, psilocybin, and sernyl on college studentsMedical Entomology and Zoology · 1965-01-01The production of psilocybin in submerged culture by Psilocybe cubensis.Lloydia · 1964-01-01[Action of psilocybin on the excitability of the nerve centers].Comptes rendus des seances de la Societe de biologie et de ses filiales · 1961-01-01