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A Phase III, Multicentre, Randomised, Double-blind, Controlled Study to Investigate the Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in Participants With Treatment-resistant DepressionClinicalTrials.gov · 2026-08-10Impact of Psilocybin on Motor Function in Healthy Participants: A Phase 1, Randomised, Triple-Blind, Dose-Finding Study.CNS drugs · 2026-08-07Ethical Complexities and Best Practices in Informed Consent Processes for Psilocybin Services: A Qualitative StudyNeuroethics · 2026-08-01In-silico toxicity study of tryptamine, psilocin, psilocybin, N,N-dimethyltryptamine, 5’-methoxy-N,N-dimethyltryptamine and O-acetylpsilocinArchives of Toxicology · 2026-08-01Psilocybin's effect on human brain synaptic plasticity.Translational psychiatry · 2026-07-15The need for another tool: Australian healthcare professionals on the use of psilocybin for existential distress in people with cancerBMC Medicine · 2026-07-06Unmixing the psychedelic connectome: Brain network traits of psilocybinNetwork Neuroscience · 2026-07-02The Australia story: Current status and future challenges for the clinical applications of psychedelics.British journal of pharmacology · 2026-07-01Acute dose-dependent effects of 4-bromo-2,5-dimethoxyphenethylamine (2C-B) compared with 3,4-methylenedioxymethamphetamine (MDMA) and psilocybin in a double-blind, placebo-controlled study in healthy participantsNeuropsychopharmacology · 2026-07-01Study Protocol for “Exploring the safety and therapeutic potential of psilocybin in the treatment of anorexia nervosa in adolescents and young adults”PLOS One · 2026-06-30Psychedelics disrupt hierarchical cortical propagations in the default mode network of humans and mice.Proceedings of the National Academy of Sciences of the United States of America · 2026-06-16Psilocybin-assisted Physiotherapy for Refractory Motor Functional Neurological Disorder: A Randomized Dose-comparison Pilot Study (P7-17.001)Neurology · 2026-06-09Correction to: Preliminary Evidence of Sleep Improvements Following Psilocybin Administration, and their Involvement in Antidepressant Therapeutic ActionCurrent Psychiatry Reports · 2026-06-05Bringing Psilocybin-Assisted Therapy to Palliative Oncology: Early Lessons from Real-World ImplementationHealthcare · 2026-06-03Spatiotemporal mapping of brain organisation following the administration of 2C-B and psilocybin.Molecular psychiatry · 2026-06-01Effects of psilocybin on sleep quality and brain microstructure in chronic cluster headacheJournal of Psychopharmacology · 2026-05-29Psilocin glucuronide in whole blood: a stable and useful biomarker of psilocybin intakeJournal of Analytical Toxicology · 2026-05-23Neural correlates of insight on psilocybin: a within-subjects, healthy volunteer studyJoCN Forum · 2026-05-08The magic of mushrooms: psilocybin influences behavior in the mangrove rivulus fish, Kryptolebias marmoratusFrontiers in Behavioral Neuroscience · 2026-05-07Human brain changes after first psilocybin useNature Communications · 2026-05-05356. Psilocybin Therapy is Associated With Decreases in Markers of Mitochondrial Stress and Inflammation in an Open-Label Clinical Trial of Parkinson’s DiseaseBiological Psychiatry · 2026-05-01Effects of psychedelic use on authoritarian attitudes revisited.Journal of psychopharmacology (Oxford, England) · 2026-05-01Evaluating the evidence for repressed memory recovery in psychedelic contextsPsychopharmacology · 2026-04-28Psilocybin use in Puerto Rico: Patterns, motivations, and personality correlates from an online surveyJournal of Psychedelic Studies · 2026-04-15Psilocybin Trends in States That Decriminalized UseJAMA · 2026-04-14Observing the mind under psychedelics: conceptual metaphors used following four once-weekly macrodoses of psilocybinPhilosophical Psychology · 2026-04-10An international mega-analysis of psychedelic drug effects on brain circuit function.Nature medicine · 2026-04-01Psilocin fosters neuroplasticity in iPSC-derived human cortical neuronseLife · 2026-03-27Psilocybin-assisted therapy for demoralisation in hospice patients: feasibility, safety and preliminary efficacy.BMJ supportive & palliative care · 2026-02-27Sense-Making Around Psilocybin in UK Women Experiencing Cancer-Related Existential Distress: An Interpretative Phenomenological Analysis.Qualitative health research · 2026-02-17Network pharmacology and molecular simulation reveal the entourage effect mechanisms of psilocybin-producing mushrooms on the brain.Scientific reports · 2026-02-14No evidence of immediate or persistent analgesic effect from a single dose of psilocybin in three mouse models of pain.Nature communications · 2026-01-22Sense-making around psilocybin in UK women experiencing cancer-related existential distress: An Interpretative Phenomenological AnalysisResearch Explorer (The University of Manchester) · 2026-01-09A novel psychedelic 5-HT receptor agonist GM-2505: The pharmacokinetic, safety, and pharmacodynamic profile from a randomized trial healthy volunteer.Journal of psychopharmacology (Oxford, England) · 2026-01-015 Years of bipolar disorder conversations on Reddit: Methods, key topics and future directions.PloS one · 2026-01-01Marketing by online tobacco retailers: An observational cross-sectional study.Tobacco induced diseases · 2026-01-01Psychedelics for the Treatment of Substance Use DisordersSUCHT - Zeitschrift für Wissenschaft und Praxis / Journal of Addiction Research and Practice · 2025-12-01Between enhancement and risk: A critical review of psychedelic microdosing.Current opinion in psychology · 2025-12-01Psilocybin-assisted physiotherapy for refractory motor functional neurological disorder: protocol for a randomised dose-comparison pilot study.Acta neuropsychiatrica · 2025-11-04Efficacy of Psilocybin and Trazodone Combination in Treatment-resistant Depression: a Randomized Controlled Proof-of-concept Study (PSILOTRAZ)ClinicalTrials.gov · 2025-10-073642 Down the rabbit hole: case reports of a hallucinogen-induced disorder of neuroperceptionPoster Abstracts · 2025-09-30Supporting Meaningful Choices: A Decision Aid for Individuals Facing Existential Distress and Considering Psilocybin-Assisted Therapy.Healthcare (Basel, Switzerland) · 2025-09-12Neuroplasticity and Neuro-Generation: The Promise of Psychedelics in Dementia CarePsychoactives · 2025-09-02Separate or inseparable? Serotonin and dopamine system interactions may underlie the therapeutic potential of psilocybin for anorexia nervosa.Physiology & behavior · 2025-09-01A lexicon for psychedelic research and treatmentDrug Science Policy and Law · 2025-08-31Psychedelic Treatment with Psilocybin: Addressing Medical Malpractice Risk and Physicians' Concerns.The Journal of law, medicine & ethics: a journal of the American Society of Law, Medicine & Ethics · 2025-07-31Clade III Synthases Add Cyclic and Linear Terpenoids to the Psilocybe Metabolome.Chembiochem: a European journal of chemical biology · 2025-07-11Psilocybin therapy for mood dysfunction in Parkinson's disease: an open-label pilot trial.Neuropsychopharmacology: official publication of the American College of Neuropsychopharmacology · 2025-07-01Exploring the Therapeutic Effects of Psychedelics Administered to Military Veterans in Naturalistic Retreat Settings.Brain and behavior · 2025-07-01A Scoping Review of Research in Naturalistic Studies with Psychedelics.Journal of psychoactive drugs · 2025-06-28Psilocybin increases emotional empathy in patients with major depression.Molecular psychiatry · 2025-06-01Psychedelics and chronic pain: self-reported outcomes on changed substance use patterns and health following naturalistic psychedelic use.British journal of pain · 2025-06-01Psychedelic therapy as relational medicine: psychosocial mechanisms in clinical and naturalistic contextsOpen MIND · 2025-05-04Psilocybin-gestützte Therapie von Depression, Angst und Suchtstörungen: Neurobiologische Grundlagen und klinische AnwendungNervenheilkunde · 2025-05-01Neurochemical characterization of 5-HTR partial agonists with simultaneous PET-MRI.Journal of cerebral blood flow and metabolism: official journal of the International Society of Cerebral Blood Flow and Metabolism · 2025-05-01Regulatory Challenges of Integrating Psychedelics into Mental Health SectorPsychoactives · 2025-04-22166. Dynamic Mediodorsal Thalamus Activity Predicts and Reflects Longitudinal Treatment Outcomes in Psilocybin Therapy for Treatment-Resistant DepressionBiological Psychiatry · 2025-04-09Psilocybin Has No Analgesic Properties in Multiple Mouse Models of Acute and Chronic PainJournal of Pain · 2025-04-01Consistent evidence that brain serotonin 2A receptor binding is positively associated with personality-based risk markers of depression.The British journal of psychiatry: the journal of mental science · 2025-03-01Oregon’s Emerging Psilocybin Services Workforce: An Environmental ScanDrug and Alcohol Dependence · 2025-02-01Examining differences in the effects and contexts of naturalistic psilocybin use for White participants vs. Participants of Color: A longitudinal online survey study.Journal of affective disorders · 2025-02-01From relaxed beliefs under psychedelics (REBUS) to revised beliefs after psychedelics (REBAS).Scientific reports · 2025-01-29Use of psychedelic treatments in psychiatric clinical practice: an EPA policy paper.European psychiatry: the journal of the Association of European Psychiatrists · 2025-01-10Benefits and Challenges of Ultra-Fast, Short-Acting Psychedelics in the Treatment of Depression.The American journal of psychiatry · 2025-01-01Roadmap for Equitable Access and Responsible Use of Psilocybin-Assisted Psychotherapy in Palliative Care.Palliative medicine reports · 2025-01-01Enhanced meaning in life following psychedelic use: converging evidence from controlled and naturalistic studies.Frontiers in psychology · 2025-01-01Clinical conceptualisation of PTSD in psilocybin treatment: disrupting a pre-determined and over-determined maladaptive interpretive framework.Therapeutic advances in psychopharmacology · 2025-01-01Neurobiology of psilocybin: a comprehensive overview and comparative analysis of experimental models.Frontiers in systems neuroscience · 2025-01-01Improved mental health outcomes and normalised spontaneous EEG activity in veterans reporting a history of traumatic brain injuries following participation in a psilocybin retreat.Frontiers in psychiatry · 2025-01-01Going Underground: Demographics, Services, and Best Practices Endorsed by Practitioners Providing Support for Naturalistic Psychedelic Use.Journal of psychoactive drugs · 2025-01-01Set and setting in psilocybin-assisted therapy: A qualitative study of patients with cancer and depression.General hospital psychiatry · 2025-01-01Narrative review of psilocybin, an important psychoactive substance with potential peri-anesthetic implicationsTrends in Anaesthesia and Critical Care · 2024-11-30Neuroimaging of Serotonergic and Psychedelic Agonist Drug Challenges in Non-Human PrimatesProceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition · 2024-11-25Preliminary Evidence of Sleep Improvements Following Psilocybin Administration, and their Involvement in Antidepressant Therapeutic Action.Current psychiatry reports · 2024-11-01Expert recommendations for Germany's integration of psychedelic-assisted therapy.BMC medical education · 2024-10-24Psilocybin restrains activity-based anorexia in female rats by enhancing cognitive flexibility: contributions from 5-HT1A and 5-HT2A receptor mechanisms.Molecular psychiatry · 2024-10-01Psilocybin and 2C-B at Encoding Distort Episodic Familiarity.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2024-10-01Psilocybin for clinical indications: A scoping review.Journal of psychopharmacology (Oxford, England) · 2024-10-01What do health professionals think about implementing psilocybin-assisted therapy in palliative care for existential distress? A World Café qualitative study.Palliative & supportive care · 2024-10-01Psilocybin increases optimistic engagement over time: computational modelling of behaviour in rats.Translational psychiatry · 2024-09-30[Psychedelic and dissociative agents in psychiatry: challenges in the treatment].Der Nervenarzt · 2024-09-01A virtual clinical trial of psychedelics to treat patients with disorders of consciousnessbioRxiv · 2024-08-19Acute Effects of Psilocybin and Salvinorin-A on Functional ConnectivityProceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition · 2024-08-13Visual hallucinations originating in the retinofugal pathway under clinical and psychedelic conditions.European neuropsychopharmacology: the journal of the European College of Neuropsychopharmacology · 2024-08-01Developing the Open Psychedelic Evaluation Nexus consensus measures for assessment of supervised psilocybin services: An e-Delphi study.Journal of psychopharmacology (Oxford, England) · 2024-08-01Acute Effects of Hallucinogens on Functional Connectivity: Psilocybin and Salvinorin-A.ACS chemical neuroscience · 2024-07-17Longitudinal experiences of Canadians receiving compassionate access to psilocybin-assisted psychotherapy.Scientific reports · 2024-07-17Developing Core Consensus Measures for Assessment of Psilocybin ServicesDrug and Alcohol Dependence · 2024-07-01[Psilocybin-Assisted Treatment of Depression, Anxiety and Substance use Disorders: Neurobiological Basis and Clinical Application].Fortschritte der Neurologie-Psychiatrie · 2024-06-01Psilocybin does not induce the vulnerability marker HSP70 in neurons susceptible to Olney's lesions.European archives of psychiatry and clinical neuroscience · 2024-06-01Psychedelics and sexual functioning: a mixed-methods study.Scientific reports · 2024-02-07Social acceptability of psilocybin-assisted therapy for existential distress at the end of life: A population-based survey.Palliative medicine · 2024-02-01Psychotherapy in Psychedelic Treatment: Safe, Evidence-Based, and NecessaryAmerican Journal of Psychiatry · 2024-01-01Effects of psilocybin and sleep quality on brain water diffusivity and microstructure in healthy individuals and chronic cluster headache patientsNeuroscience Applied · 2024-01-01Insights into the serotonergic mechanisms of psilocybin-induced improvements in anorexia-like behaviour in female ratsNeuroscience Applied · 2024-01-01Potential analgesic effects of psychedelics on select chronic pain conditions: A survey study.European journal of pain (London, England) · 2024-01-01Psilocybin and Motor Function: A Triple-Blind, Dose-Finding Study in Healthy Participants.Psychiatric research and clinical practice · 2024-01-01Present and future of metabolic and metabolomics studies focused on classical psychedelics in humans.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2023-12-31Cost-effectiveness of psilocybin-assisted therapy for severe depression: exploratory findings from a decision analytic model.Psychological medicine · 2023-12-01Peak Experiences: Lessons Learned from a Feasibility Study of Psilocybin-assisted Therapy for Demoralization in Patients Receiving Hospice CareJournal of the Academy of Consultation-Liaison Psychiatry · 2023-11-01Psilocybin induces acute and persisting alterations in immune status in healthy volunteers: An experimental, placebo-controlled study.Brain, behavior, and immunity · 2023-11-01Comparative acute effects of mescaline, lysergic acid diethylamide, and psilocybin in a randomized, double-blind, placebo-controlled cross-over study in healthy participants.Neuropsychopharmacology: official publication of the American College of Neuropsychopharmacology · 2023-10-01Psychedelics, With a Focus on Psilocybin: Issues for the Clinician.Journal of psychiatric practice · 2023-09-01Co-use of MDMA with psilocybin/LSD may buffer against challenging experiences and enhance positive experiences.Scientific reports · 2023-08-22How does psilocybin therapy work? An exploration of experiential avoidance as a putative mechanism of change.Journal of affective disorders · 2023-08-01Psilocybin prevents reinstatement of alcohol seeking by disrupting the reconsolidation of alcohol-related memories.Psychopharmacology · 2023-07-01In vivo mapping of pharmacologically induced functional reorganization onto the human brain's neurotransmitter landscape.Science advances · 2023-06-16Canalization and plasticity in psychopathology.Neuropharmacology · 2023-03-15[Psychedelic Therapy with Psilocybin and Psychotherapy - Where do we Stand?].Psychotherapie, Psychosomatik, medizinische Psychologie · 2023-03-01Single-dose psilocybin-assisted therapy in major depressive disorder: A placebo-controlled, double-blind, randomised clinical trial.EClinicalMedicine · 2023-02-01Acute neurovascular effects of psilocybin administration in healthy humans: Implications for cerebral blood flow measurements using arterial spin labellingNeuroscience Applied · 2023-01-01Change in whole blood BDNF after escitalopram or psilocybin intervention in patients with depression and healthy controlsNeuroscience Applied · 2023-01-01Among psychedelic-experienced users, only past use of psilocybin reliably predicts nature relatedness.Journal of psychopharmacology (Oxford, England) · 2023-01-01High time? Psychedelics on cannabis-like fast track to legalizationCanadian Medical Association Journal · 2022-12-17The Watts Connectedness Scale: a new scale for measuring a sense of connectedness to self, others, and world.Psychopharmacology · 2022-11-01Psilocybin: a revolution in psychedelic medicines in the US?BMJ (Clinical research ed.) · 2022-10-06Effects of psilocybin versus escitalopram on rumination and thought suppression in depression.BJPsych open · 2022-09-06[The use of psilocybin for treatment-resistant depression].Laeknabladid · 2022-09-01Examining Attitudes to Psilocybin: Should Candidates for Medical Psilocybin be Required to Pass a Contextual Suitability Test?Journal of Humanistic Psychology · 2022-08-18Analytical profile, in vitro metabolism and behavioral properties of the lysergamide 1P-AL-LAD.Drug testing and analysis · 2022-08-01From Relaxed Beliefs Under Psychedelics (REBUS) to Revised Beliefs After Psychedelics (REBAS): Preliminary Development of the RElaxed Beliefs Questionnaire (REB-Q)PsyArXiv · 2022-07-07Direct comparison of the acute effects of lysergic acid diethylamide and psilocybin in a double-blind placebo-controlled study in healthy subjects.Neuropsychopharmacology: official publication of the American College of Neuropsychopharmacology · 2022-05-01Unraveling the Mysteries of Mental Illness With Psilocybin.Cureus · 2022-05-01Psilocybin Therapy of Psychiatric Disorders Is Not Hampered by hERG Potassium Channel-Mediated Cardiotoxicity.The international journal of neuropsychopharmacology · 2022-04-19Acute Effects of Psilocybin After Escitalopram or Placebo Pretreatment in a Randomized, Double-Blind, Placebo-Controlled, Crossover Study in Healthy Subjects.Clinical pharmacology and therapeutics · 2022-04-01Psilocin acutely alters sleep-wake architecture and cortical brain activity in laboratory miceTranslational Psychiatry · 2022-02-23Comparison of subjective, autonomic, and endocrine effects of LSD and psilocybin in healthy subjectsNeuroscience Applied · 2022-01-01Raising awareness: The implementation of medical cannabis and psychedelics used as an adjunct to standard therapy in the treatment of advanced metastatic breast cancerDrug Science Policy and Law · 2022-01-01Psychedelics and health behaviour change.Journal of psychopharmacology (Oxford, England) · 2022-01-01Decreases in State and Trait Anxiety Post-psilocybin: A Naturalistic, Observational Study Among Retreat Attendees.Frontiers in psychiatry · 2022-01-01Examining attitudes to psilocybin: Should candidates for medical psilocybin be required to pass a contextual suitability testPsyArXiv · 2021-11-23Psychedelic experience dose-dependently modulated by cannabis: results of a prospective online surveyPsychopharmacology · 2021-11-03Psychedelics and Mindfulness: A Systematic Review and Meta-AnalysisPsyArXiv · 2021-10-11Psychedelic resting-state neuroimaging: a review and perspective on balancing replication and novel analysesPsyArXiv · 2021-06-10Whitewashing psychedelics: racial equity in the emerging field of psychedelic-assisted mental health research and treatmentDrugs Education Prevention and Policy · 2021-04-29Spontaneous and deliberate creative cognition during and after psilocybin exposure.Translational psychiatry · 2021-04-08[Ketamine, psilocybin, and rapid acting antidepressant: new promise for psychiatry?].L'Encephale · 2021-04-01Psychedelics and Health Behavior Change - Journal of Psychopharmacology (in press)PsyArXiv · 2021-03-24P.214 (Sub)acute effects of psilocybin on creative cognition: a double-blind, placebo-controlled experimental studyEuropean Neuropsychopharmacology · 2021-02-25Psilocin acutely disrupts sleep and affects local but not global sleep homeostasis in laboratory micebioRxiv · 2021-02-17A Single Dose of Psilocybin Increases Synaptic Density and Decreases 5-HT Receptor Density in the Pig Brain.International journal of molecular sciences · 2021-01-15Effects of a single dose of psilocybin on behaviour, brain 5-HT receptor occupancy and gene expression in the pig.European neuropsychopharmacology: the journal of the European College of Neuropsychopharmacology · 2021-01-01Sustained, Multifaceted Improvements in Mental Well-Being Following Psychedelic Experiences in a Prospective Opportunity Sample.Frontiers in psychiatry · 2021-01-01Therapeutic Alliance and Rapport Modulate Responses to Psilocybin Assisted Therapy for Depression.Frontiers in pharmacology · 2021-01-01P.804A single dose of psilocybin increases synaptic density and decreases 5-HT2A receptor density in the pig brainEuropean Neuropsychopharmacology · 2020-11-01Me, myself, bye: regional alterations in glutamate and the experience of ego dissolution with psilocybin.Neuropsychopharmacology: official publication of the American College of Neuropsychopharmacology · 2020-11-01Perceived harm, motivations for use and subjective experiences of recreational psychedelic 'magic' mushroom use.Journal of psychopharmacology (Oxford, England) · 2020-09-01Reviewing the Potential of Psychedelics for the Treatment of PTSD.The international journal of neuropsychopharmacology · 2020-06-24Nothing Ventured, Nothing Gained: Regulations Cripple Potentially Life-Saving Research of Illicit Substances.ACS chemical neuroscience · 2020-05-20P.324 Acute effects of psilocybin on glutamate concentration levels, functional connectivity and subjective stateEuropean Neuropsychopharmacology · 2020-01-28[Addictions].Revue medicale suisse · 2020-01-15P.228 The polypharmacological profile of psilocybin and potential behavioural effects of very low dosesEuropean Neuropsychopharmacology · 2019-12-01Replication and extension of a model predicting response to psilocybin.Psychopharmacology · 2019-11-01Motives for Classical and Novel Psychoactive Substances Use in Psychedelic Polydrug UsersContemporary Drug Problems · 2019-09-01Unpredictable Behavior Under the Influence of "Magic Mushrooms": A Case Report and Review of the Literature.Journal of forensic sciences · 2019-07-01Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms.Scientific reports · 2017-10-13[New patterns of substance use and abuse among French adolescents, a knowledge synthesis].L'Encephale · 2017-08-01The Effects of LSD and Psilocin on Anxiety-Related Behaviours in ZebrafishStudent Research Proceedings · 2017-05-15Psychedelics not linked to mental health problems or suicidal behavior: a population study.Journal of psychopharmacology (Oxford, England) · 2015-03-01Over 30 million psychedelic users in the United States.F1000Research · 2013-01-01Psychedelics and mental health: a population study.PloS one · 2013-01-01The Meixner test in the detection of α-amanitin and false-positive reactions caused by psilocin and 5-substituted tryptaminesAnnals of Emergency Medicine · 2004-08-01Strategies for the capillary electrophoretic separation of indole alkaloids in Psilocybe semilanceata.Electrophoresis · 1998-01-01Determination of psilocybin in Psilocybe semilanceata by capillary zone electrophoresis.Journal of chromatography. B, Biomedical sciences and applications · 1997-07-04