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Publication history
Mindfulness-Based Psilocybin-Assisted Therapy (MB-PAT) for cancer-related demoralization in Canada: The case for a hybrid group-based delivery modelPsychedelics · 2026-12-01Changes in anxiety, quality of life, and functioning following psilocybin-assisted therapy in veterans with treatment-resistant depressionJournal of Affective Disorders · 2026-11-01Chronic psilocin microdosing produces limited behavioral effects and does not enhance neurogenesis in ratsPharmacology Biochemistry and Behavior · 2026-10-01Psilocybin for Treatment-Resistant Major Depression: Efficacy, Safety and Therapeutic MechanismsUnknown journal · 2026-09-24Effects of Psilocybin Microdosing on Cognition, Mood and Quality of Life: A Pilot StudyClinicalTrials.gov · 2026-09-24Evaluating the Feasibility, Clinical Effects, and Safety of Psilocybin-assisted Psychotherapy for Treatment-resistant Obsessive-compulsive Disorder: An Open-label Clinical TrialClinicalTrials.gov · 2026-09-24Psilocybin-Assisted Psychotherapy for the Treatment of Severe Alcohol Use Disorder: A Double-Blind, Dose-Comparison Concurrent Control Randomized TrialClinicalTrials.gov · 2026-09-24Psilocybin and Contrasting Musical Compositions: Effects on Music-Evoked Emotional Responses in Healthy AdultsmedRxiv · 2026-09-23Preclinical Anxiolytic- and Antidepressant-like Effects of α,α-Trehalose, a Bioactive Compound Identified in Psilocybe cubensisMolecules · 2026-09-23Psilocybin for Chronic Pelvic Pain (CPP) in Women: A Pilot Feasibility StudyClinicalTrials.gov · 2026-09-23Apomorphine and psilocybin to improve recovery from coma in the intensive care unit: protocol for a prospective, open-label, dose-escalation study.BMJ open · 2026-09-22Reply to 'Methodological concerns and interpretative limitations of assessing subjective effects of ketamine'.Npj mental health research · 2026-09-22ADEPT: Augmenting DBT Effectiveness With Psilocybin-Assisted TherapyClinicalTrials.gov · 2026-09-22Acute psilocybin or ethocybin leads to a sustained increase in Pavlovian aversion memory in male miceFrontiers in Pharmacology · 2026-09-22Curious about Psilocybin? Prevalence and correlates of interest among adults with chronic pain.Authorea Preprints · 2026-09-21Prior trauma shapes the effects of psilocybin on stress sensitization in mice.Neuroscience letters · 2026-09-21EFFICACY AND SAFETY OF PSILOCYBIN IN TREATMENT-RESISTANT DEPRESSION: A REVIEWInternational Journal of Innovative Technologies in Social Science · 2026-09-21A Randomized, Double-Blind, Placebo-Controlled Single-Ascending-Dose Study to Identify a Subperceptual Dose of Psilocybin in Healthy AdultsPharmaceuticals · 2026-09-21Pharmacokinetics and safety of a modified-release psilocybin formulation: A SAD Phase I trial in normal-weight and overweight/obese participants.British journal of clinical pharmacology · 2026-09-21The serotonin 1B receptor as a target for the treatment of depression and anxiety.Expert opinion on therapeutic targets · 2026-09-21An Open-Label, Dose-Escalation Trial of Psilocybin-Assisted Therapy for Bipolar II Depression.The Journal of clinical psychiatry · 2026-09-21A Case of Acute Mania and Rhabdomyolysis Associated With Long-Term, Daily Psilocybin Use.Journal of clinical psychopharmacology · 2026-09-21Psilocybin in the Treatment of Methamphetamine Use DisorderClinicalTrials.gov · 2026-09-21Efficacy of Psilocybin and Trazodone Combination in Treatment-resistant Depression: a Randomized Controlled Proof-of-concept Study (PSILOTRAZ)ClinicalTrials.gov · 2026-09-21Psychedelics and suicidality: A double-edged sword - risks, mechanisms, and moving forward.European neuropsychopharmacology: the journal of the European College of Neuropsychopharmacology · 2026-09-19Exploring the Therapeutic Potential of Psilocybin: A Comprehensive Review of Clinical Trial Evidence and Implications for Rescheduling.Mini reviews in medicinal chemistry · 2026-09-18Perceptions and Attitudes on Psilocybin-Assisted Therapy among Underrepresented People with Cancer.Journal of pain and symptom management · 2026-09-18High ventilation breathwork as a non-pharmacological model for inducing psychedelic-like states: expert evaluations of therapeutic potential and risk.Npj mental health research · 2026-09-17Development and Psychometric Validation of the ‘Psychedelic Flourishing Scale’PsyArXiv · 2026-09-17Psilocybin restores social novelty investigation in male SAPAP3 knockout mice and engages prefrontal-hippocampal circuitry.Molecular psychiatry · 2026-09-17Neuroplasticity Enhancement From Cognitive Training Reinforced by Psilocybin (NECTAR) in Aging and Alzheimer's DiseaseClinicalTrials.gov · 2026-09-17Exploratory safety, tolerability, and feasibility of psilocybin-assisted psychotherapy for adults with co-occurring treatment-resistant depression and cluster B personality disordersnpj Mental Health Research · 2026-09-16Surrender, disidentification, and reappraisal: a qualitative comparison of psilocybin responders and non-responders in treatment-resistant OCDFrontiers in psychiatry · 2026-09-16Level of preparedness to use psilocybin among individuals seeking psychedelic risk reduction: a retrospective study of a pilot psychiatric consultation serviceFrontiers in Public Health · 2026-09-16A Multicenter Phase 1 Safety and Tolerability Trial of Psilocybin in Healthy Older AdultsClinicalTrials.gov · 2026-09-16Psilocybin-assisted Existential, Attachment and RelationaL (PEARL) Therapy for Patients With Advanced Cancer: A Randomized Controlled TrialClinicalTrials.gov · 2026-09-15Psilocybin and ayahuasca in treatment-resistant depression: clinical evidence, methodological constraints and ethical challenges: a narrative reviewFrontiers in Psychiatry · 2026-09-155-HT2A receptor activation is dispensable for psilocybin-induced fear extinction and neuroplasticity in mice.Chinese medical journal · 2026-09-15PRoMiSS: Psilocybin and the Role of Music in Set and SettingClinicalTrials.gov · 2026-09-15Targeting Reward Circuits: Psilocybin as a Novel Therapy for Residual AnhedoniaClinicalTrials.gov · 2026-09-15Psilocybin-Assisted Therapy for Treatment-Resistant Depression in Bipolar II Disorder: A Randomized Controlled TrialClinicalTrials.gov · 2026-09-15Resetting the hippocampal buffer: a neurocognitive account of psychedelic therapy for anxiety-related psychopathology.Psychopharmacology · 2026-09-15MDMA and Psilocybin Regulate Oligodendrocyte-Lineage Cell Numbers and Anxiety-Like Behaviors in a Rat Model of Fear.Biological psychiatry · 2026-09-15Psychedelics and the Extracellular Matrix: Rewiring Neuroplasticity and Metaplasticity for Next-Generation Psychiatric Therapies.Biological psychiatry · 2026-09-15Comparative Policy Analysis of Psychedelic Therapy Regulation in Australia, Brazil, and the USAApplied Drug Research Clinical Trials and Regulatory Affairs · 2026-09-14Correlation of Ketamine and Classic Psychedelics with Pain-Related Neural Connectivity: A Scoping Review of Clinical Experiments on a Potential Therapeutic Target Concerning Ketamine and Classical Psychedelics Administration for Pain ReliefPsychedelic Medicine · 2026-09-14A Phase 1b Study to Evaluate the Safety and Tolerability of MLS101 Treatment for Premenstrual Dysphoric Disorder (PMDD)ClinicalTrials.gov · 2026-09-14Pilot Study on the Effects of Psilocybin on Belief Updating and Insight FormationClinicalTrials.gov · 2026-09-14Psilocybin Administration With 5-HT1a BlockadeClinicalTrials.gov · 2026-09-14Neural correlates and behavioral outcomes of aesthetic chills and their prosthetic augmentationPsyArXiv · 2026-09-13Implications of Potential US FDA Approval of Psychedelics or Psychedelic-Adjacents Such as Ibogaine for Pharmacy in Japan.Cureus · 2026-09-13[The use of psychedelics in psychiatry].Orvosi hetilap · 2026-09-13Modulating the Thermodynamics and Kinetics of Psychedelics at Serotonin Receptors via Terahertz WavesThe Journal of Physical Chemistry B · 2026-09-12Psilocybin and Chronic Neuropathic and Centralized Pain: Converging Mechanisms in Central Sensitization, Neuroplasticity, and Network OrganizationAnesthesia Research · 2026-09-11TRIP - TReatment to Improve Depression and/or Anxiety Using Psilocybin-Assisted Psychotherapy in Patients With Advanced Cancer on Maintenance TherapyClinicalTrials.gov · 2026-09-11Multilevel Mechanisms and Clinical Efficacy of Psilocybin in Depression Treatment: A Systematic ReviewInternational Journal of Molecular Sciences · 2026-09-10Cardiac Arrhythmia Associated with Psychoactive Drugs: An analysis of the FDA Adverse Event Reporting SystemmedRxiv · 2026-09-10Psilocybin restores spatial memory but not fronto-hippocampal synchrony in a rat model of Alzheimer's disease.Neuroscience research · 2026-09-10What Is Psilocybin?JAMA · 2026-09-10Psilocybin-associated microRNA changes in the pig brain: Establishing an nCounter pipeline for cross-species microRNA quantification.European journal of pharmacology · 2026-09-10Psilocybin selectively suppresses novelty-induced grooming via 5-HT2B receptors: A microstructure analysis in Wistar rats.Progress in neuro-psychopharmacology & biological psychiatry · 2026-09-09Psychedelic 4-AcO-DMT attenuated looming-induced freezing behaviors by activating PrL CaMKIIα neurons in mice.Molecular psychiatry · 2026-09-09A Two-Threshold Model of Psilocybin Response Explains Variability in Psychedelic-Assisted Therapy for Treatment-Resistant DepressionResearch Square · 2026-09-09Craving Reduction and Smoking Outcomes in Psilocybin-Assisted and Standard Cessation Care.Revista brasileira de psiquiatria (Sao Paulo, Brazil: 1999) · 2026-09-09A Randomized Double-blinded Controlled Trial for the Treatment of Persisting Symptoms After Concussion With Psilocybin-assisted Therapy: A Safety and Feasibility TrialClinicalTrials.gov · 2026-09-09A Double Blind, Randomized Trial Investigating the Safety, Feasibility, and Mechanisms of Psychedelics in Healthy Older Adults With Low Well-being as Moderated by Biomarkers for Preclinical Alzheimer's DiseaseClinicalTrials.gov · 2026-09-09Psilocybin-assisted Therapy for Post-Traumatic Stress Disorder in Survivors of Intimate Partner ViolenceClinicalTrials.gov · 2026-09-08Mystical but not challenging experiences predict symptom improvement after psilocybin for treatment-resistant OCDFrontiers in Psychiatry · 2026-09-08Who Is Reached by Supervised Psilocybin Services? Oregon Services Versus National Psilocybin UsemedRxiv · 2026-09-07Brain-wide reconfiguration of burst firing by psilocybin reveals 5-HT2A-dependent circuit dynamicsbioRxiv · 2026-09-07Psilocybin as an emerging anxiolytic: mechanisms, evidence, and open questions.Neuropsychopharmacology: official publication of the American College of Neuropsychopharmacology · 2026-09-06Daily briefing: Psilocybin blocks side-effect of chemotherapy in mice.Nature · 2026-09-04Psilocybin-induced changes in electroencephalography link acute and long-term effects.Journal of psychopharmacology (Oxford, England) · 2026-09-04One dose of Psilocybin modulates Brain Activity among Depressive patients: Preliminary Neuroimaging Results from the PSILODAC StudyEuropean psychiatry: the journal of the Association of European Psychiatrists · 2026-09-04Effects of Psilocybin in Obsessive Compulsive DisorderClinicalTrials.gov · 2026-09-04Pilot Study of Serotonin 2A Receptor (5-HT2A) Agonist Psilocybin for Depression in Patients With Mild Cognitive Impairment or Early Alzheimer's DiseaseClinicalTrials.gov · 2026-09-04Psilocybin and Affective Function in Chronic Lower Back Pain DepressionClinicalTrials.gov · 2026-09-04Psilocybin and MDMA for Post-traumatic Stress Disorder (PTSD)ClinicalTrials.gov · 2026-09-04A Phase 2b/3, Multicentre, Randomised, Double-blind, Controlled Trial, With an Open Label Extension, to Investigate the Efficacy, Safety, and Tolerability of COMP360 in Participants With Post-traumatic Stress DisorderClinicalTrials.gov · 2026-09-04Study of Psilocybin Assisted Psychotherapy to Address Fear of Recurrence in Patients Diagnosed With Early-stage Breast Cancer and Ovarian Cancer in RemissionClinicalTrials.gov · 2026-09-04Psilocybin prevents chemotherapy-induced peripheral neuropathy through mitochondrial trafficking preservation.Science (New York, N.Y.) · 2026-09-03Psilocybin Therapy for Depression and Anxiety in Parkinson's Disease: a Pilot StudyClinicalTrials.gov · 2026-09-03A response to the letter to editor: Breaking the chains of depression: A systematic review and meta-analysis of psilocybin therapy.Journal of affective disorders · 2026-09-02Through the Looking-Glass: A Scoping Review of Psychological Mechanisms of Psychedelic-Assisted Therapy for Substance Use DisordersCurrent Addiction Reports · 2026-09-02High vs. Low-Dose Group-Based Psilocybin-Assisted Therapy (PAT) With or Without Mindfulness-Based (MB) Preparation and Integration for Demoralization in Adults With Advanced Cancer (PAT-MIND): A Pilot Feasibility 2x2 Factorial Multisite TrialClinicalTrials.gov · 2026-09-02Neurobehavioral Mechanisms of Psilocybin-assisted Treatment for Alcohol Use DisorderClinicalTrials.gov · 2026-09-02The Role of the Subjective Experience in Supporting Positive Effects Following Psilocybin: a Randomized, Controlled Clinical Trial Using Risperidone in Healthy AdultsClinicalTrials.gov · 2026-09-02Psilocybin-Assisted Therapy for Physician Well-Being and Burnout: Feasibility, Safety, Clinical Effectiveness and Biomarkers of Response [PAT-B (Psilocybin-Assisted Therapy for Physician Well-Being and Burnout)]ClinicalTrials.gov · 2026-09-02Age and Cannabis Co-Use Are Associated with Differences in Experience and Perceived Benefits of Psilocybin: A Retrospective Study.Journal of psychoactive drugs · 2026-09-02Psilocybin, From Ancestral Use to Therapeutic Potential: A Multidimensional Review of Its Pharmacological Basis and Current Perspectives.Human psychopharmacology · 2026-09-01Patterns of Psychedelic Use in Italy: Insights from the Global Psychedelic SurveyClinical Neuropsychopharmacology and Addiction · 2026-09-01Factors Associated with Intentions to Use Psilocybin for Mental Health in Relation to Psychotherapy, Psychiatric Medications, and Natural/Synthetic Options.Journal of psychoactive drugs · 2026-09-01Mycotoxins in Basidiomycete Mycelium and Fruiting Bodies: Implications for Eu Novel Food Assessment and Selected International Regulatory Frameworks.Comprehensive reviews in food science and food safety · 2026-09-01AMCP Market Insights: Optimizing managed care approaches to treatment-resistant depression.Journal of managed care & specialty pharmacy · 2026-09-01Comparing synthetic and biological therapy for the treatment of cluster headache: what is needed and when?Expert review of neurotherapeutics · 2026-09-01Active placebo control interventions in pharmacological trials: a scoping review of the development process and a terminological analysis.Journal of clinical epidemiology · 2026-09-01Psychedelics stores, their regulation and public health: knowledge, perceptions, attitudes and opinions of Canadians.The International journal on drug policy · 2026-09-01Assessing The Readiness of Psychiatrists in Louisiana to Incorporate Psilocybin into Clinical Practice-Lessons Learned from a State Underrepresented in Clinical Psychedelic Research.Psychedelic medicine (New Rochelle, N.Y.) · 2026-09-01A Nature-Themed Video Intervention Increases Nature Relatedness in Psilocybin-Assisted Psychotherapy for Alcohol Use Disorder.Psychedelic medicine (New Rochelle, N.Y.) · 2026-09-01Group Retreat Psilocybin Therapy for People with Metastatic Cancer with Anxiety and Depression: A Rite of Passage Facilitation Model for a Phase 1/2 Study.Psychedelic medicine (New Rochelle, N.Y.) · 2026-09-01A suite of engineered mice for interrogating psychedelic drug actions.Nature neuroscience · 2026-09-01Contribution of the Serotonin 5-HT2A Receptor to the Therapeutic Effect of Psilocin on Social Behavior Deficits in Mice Repeatedly Exposed to Social Defeat Stress.Neuropsychopharmacology reports · 2026-09-01Balancing safety and access in Oregon's psilocybin services.The International journal on drug policy · 2026-09-01Genome-based optimization of psilocybin and N,N-dimethyltryptamine biosynthetic pathways in E. coli using CRISPR-associated transposases.Metabolic engineering · 2026-09-01Cardiovascular effects associated with acute recreational drug toxicity presentations to the emergency department: a European drug emergencies network (Euro-DEN plus) study.Clinical toxicology (Philadelphia, Pa.) · 2026-09-01PRISMatic: A Phase 1b Randomized, Double-Armed, Parallel-Group, Placebo-Controlled Trial of Psilocybin Efficacy With or Without Pimavanserin PretreatmentClinicalTrials.gov · 2026-08-31NeuroGuard: Psilocybin Trial for Preventing Chemo-induced NeuropathyClinicalTrials.gov · 2026-08-31An 8-week Phase 2 Clinical Trial to Evaluate the Safety, Tolerability and Efficacy of Psilocybin-assisted-psychotherapy in Adults With Cannabis Use Disorder: A Proof-of-Concept StudyClinicalTrials.gov · 2026-08-31Differential effects of psilocybin derivatives on fentanyl-induced conditioned place preference in male and female mice.Journal of psychopharmacology (Oxford, England) · 2026-08-30A randomized crossover trial comparing the acute physiological and psychological effects of botanical formulations of oral psilocybin, oral psilocin, and sublingual psilocin.Journal of psychopharmacology (Oxford, England) · 2026-08-29Oregon's state-regulated psilocybin services: Early real-world safety signals.Journal of psychopharmacology (Oxford, England) · 2026-08-28Psilocybin-Assisted Psychotherapy for Posttraumatic Stress Disorder in Military Veterans: A Pilot Feasibility StudyClinicalTrials.gov · 2026-08-28Development of a Physiologically Based Pharmacokinetic/Pharmacodynamic Model of Psilocybin/Psilocin from Psilocybe cubensis (Magic Mushroom) in Treatment-Resistant Depression.European journal of drug metabolism and pharmacokinetics · 2026-08-28A Randomised, Placebo Controlled Trial of Psilocybin in Treatment Resistant Depression: A Feasibility StudyClinicalTrials.gov · 2026-08-28“Am I a candidate for magic mushrooms?” A mystery shopper study of Oregon psilocybin service centersHealth Affairs Scholar · 2026-08-27Pilot study comparing the effects of high dose THC to high dose psilocybin and placebo in the set and setting of a classic psychedelic therapy session.Psychopharmacology · 2026-08-27Medical and Psychiatric Consultation for Patients Considering State-Regulated Psilocybin Services: A Risk-Reduction Model and Two Illustrative CasesResearch Square · 2026-08-26Aquahenosis: a non-pharmacological altered state of consciousness induced by floatation-REST in individuals with anxiety and depression.Neuroscience of consciousness · 2026-08-26Mystical and affective features of naturalistic psychedelic experiences: A comparison of dictionary-based and LLM-based text analysis methodsResearch Square · 2026-08-25Psilocybin collapses visual change detection and drives cortical dynamics toward a state of surprisebioRxiv · 2026-08-25Beyond head-twitch response: Acute psilocybin affects spontaneous behaviors in rats in a dose-dependent manner.Journal of psychopharmacology (Oxford, England) · 2026-08-25Toward an Optimal Framework for Psilocybin Regulation: A Comparison of State Regulatory Approaches Across Key Dimensions.The Journal of legal medicine · 2026-08-25Distinct response of resting-state brain networks to psilocybin in autismmedRxiv · 2026-08-22Adverse Effect-Related Language in Recreational Psychedelic and non-Psychedelic Substance Experience Reports.Journal of studies on alcohol and drugs · 2026-08-22Complex Fatal Self-Harm Under Psilocybin Intoxication: Suicidal Manner of Death or Not?Academic forensic pathology · 2026-08-21The trials of translating psilocybin treatment from research to practice.Nature medicine · 2026-08-21Evaluating the Role of Psilocybin Monitors in Psilocybin Therapy for Treatment Resistant Depression: A Pilot Randomized Clinical TrialClinicalTrials.gov · 2026-08-21Psilocybin lengthens hippocampal sharp wave ripplesbioRxiv · 2026-08-20Low-dose lysergic acid diethylamide alters subjective visual perception but not visual contrast surround suppression.Neuroscience of consciousness · 2026-08-20The subtle science: a systematic review of psilocybin magic mushroom and truffle microdosingFrontiers in Psychiatry · 2026-08-19Safety and Mental Health Outcomes of Oregon State-Regulated Psilocybin ServicesJAMA Network Open · 2026-08-19Prospective real-world evidence of mental health outcomes following supervised psilocybin services within Oregons state-regulated modelmedRxiv · 2026-08-19Psilocybin in Chronic Low Back Pain: An Integrative Study of Lab-Based Mechanisms and Real-World Physical Therapy OutcomesClinicalTrials.gov · 2026-08-19An Exploratory Pilot Study of Palliadelic Treatment to Reduce Psychological Distress in People With Pancreatobiliary and Other Advanced Gastrointestinal CancersClinicalTrials.gov · 2026-08-19Psychedelics align brain activity with context.Nature · 2026-08-19Assessing Canadian Policy Readiness for Psychedelic-Assisted Therapy in Cancer CareUnknown journal · 2026-08-17Psilocybin-assisted psychotherapy for substance use disorders as a complex intervention: A systematic review of efficacy, mechanisms and psychotherapeutic frameworks.Journal of psychopharmacology (Oxford, England) · 2026-08-17An Examination of Psilocybin Effects on Biomarkers of Longevity, Healthy Aging, and Purpose in LifeClinicalTrials.gov · 2026-08-17Defining 'psychedelic'.Journal of psychopharmacology (Oxford, England) · 2026-08-17Subacute and long-term changes in cognitive functioning after administration of classic psychedelics, MDMA and ketamine: A systematic review of clinical and preclinical evidence.Neuroscience and biobehavioral reviews · 2026-08-14The Therapeutic Potential of Psilocybin in Anorexia Nervosa in Young AdultsClinicalTrials.gov · 2026-08-14Safety for Home Administration of Microdose Psilocybin UseClinicalTrials.gov · 2026-08-14A Multi-site Randomized Controlled Trial of Psilocybin for Treatment-Resistant Depression (TRD) in VeteransClinicalTrials.gov · 2026-08-14Ayahuasca and Salvia divinorum as contrasting modes of consciousness reorganization: Implications for psychedelic-assisted psychotherapyJournal of Psychedelic Studies · 2026-08-13Efficacy and Safety of Psychedelic Microdosing on Psychological Outcomes in Healthy Adults: A Systematic Review and Meta-analysis.CNS drugs · 2026-08-13Role of Experience, Conscious Awareness, and Plasticity in Psilocybin's Behavioral Effects - Follow-Up Study (The RECAP 2 Study)ClinicalTrials.gov · 2026-08-13Processing Intergenerational Trauma With Psilocybin-Assisted TherapyClinicalTrials.gov · 2026-08-13The Effects of Psilocybin on Self-Focus and Self-Related Processing in Major Depressive DisorderClinicalTrials.gov · 2026-08-13PsiloStudy: A Phase 2 Single-site, Double-blind, Placebo-controlled, Randomized Clinical Trial With an Open-label Extension Phase to Examine the Safety, Subjective Experiences, Acute Effects, and Suitability of Psilocybin Combined With Psychological Support (Psi-PS) for Military Veterans and First Responders With Co-occurring Alcohol Use Disorder (AUD) and Posttraumatic Stress Disorder (PTSD)ClinicalTrials.gov · 2026-08-13Real-world use, safety, and mental health efficacy of regulated psilocybin services in Oregon and ColoradomedRxiv · 2026-08-12Exploring the In Vitro Effect of Psilocybin on the Composition and Metabolic Activity of Gut Microbiota in Individuals with Severe AnxietyDrugs and Drug Candidates · 2026-08-12Psilocybin-Assisted Therapy in Psychiatry: A Narrative Clinical Review of Mechanisms, Therapeutic Applications, and Emerging Evidence (2025-2026)Journal of Clinical Medicine · 2026-08-12TRIPS - Treatment to Improve Depression and/or Anxiety Using Psilocybin-assisted Psychotherapy in Cancer SurvivorsClinicalTrials.gov · 2026-08-12Acceptability & Safety of Two Sequential Doses of Psilocybin in Bipolar Disorder II Depression and SuicidalityClinicalTrials.gov · 2026-08-12Low-Dose Psilocybin Therapy for Palliative Care Patients With Chronic Cancer Pain Requiring OpioidsClinicalTrials.gov · 2026-08-12A Phase 2a, Placebo-Controlled Randomized, Double-Blind Trial to Evaluate the Safety, Tolerability, and Preliminary Efficacy of Psilocybin Oral Solution in Adults With Generalized Anxiety DisorderClinicalTrials.gov · 2026-08-12Effects of naturalistic psychedelic use on executive functioning: An online survey of lifetime history and recent use in university students.Progress in neuro-psychopharmacology & biological psychiatry · 2026-08-11Psychedelics and astrocytes: a hypothesis-driven perspective on neuro-glial integration, network plasticity, and neuroimmune reprogramming.Molecular psychiatry · 2026-08-11Psilocybin Recovery Intervention for Stopping Methamphetamine UseClinicalTrials.gov · 2026-08-11Effects of Psilocybin in Patients With Amyotrophic Lateral SclerosisClinicalTrials.gov · 2026-08-11Circulating MicroRNAs and Their Associations with Neurotrophic, Inflammatory and Glutamate Markers in Healthy VolunteersbioRxiv · 2026-08-10Temporal effects of a single oral dose of psilocybin on plasma circulating miRNAs in healthy young adultsbioRxiv · 2026-08-10Psilocybin acutely dissociates cognitive and affective empathy, with empathic concern predicting persisting positive psychological effectsbioRxiv · 2026-08-10An Open-Label Trial Protocol to Test Menstrual Cycle Effects and Tolerance to Low-Dose Psilocybin in Healthy Menstruating Persons.Pharmacology · 2026-08-10An Investigation of Strategies to Understand and Optimize the Antidepressant Effects of Psilocybin (The OPTIMIZE Study)ClinicalTrials.gov · 2026-08-10A Phase III, Multicentre, Randomised, Double-blind, Controlled Study to Investigate the Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in Participants With Treatment-resistant DepressionClinicalTrials.gov · 2026-08-10Safety, Tolerability, Outcomes of Psilocybin for Depression (STOP Depression) in Veterans With Spinal Cord InjuryClinicalTrials.gov · 2026-08-10A Phase III, Multicentre, Randomised, Double-blind, Placebo-controlled Study to Investigate the Efficacy, Safety, and Tolerability of COMP360 in Participants With Treatment-resistant DepressionClinicalTrials.gov · 2026-08-10Neurobiological Effects of Psilocybin in Treatment Resistant Bipolar Depression: An Emotional-Processing fMRI Pilot StudyClinicalTrials.gov · 2026-08-10'So many relationships in the room': Participant perspectives on the affordances and challenges of co-therapy in psychedelic assisted therapy.Psychology and psychotherapy · 2026-08-10Microdosing psychedelics: What, why, when, and how often? Insights from an international survey of people who use psychedelics.The International journal on drug policy · 2026-08-07Feasibility and Tolerability of Psilocybin for Phantom Limb Pain.The journal of pain · 2026-08-07Impact of Psilocybin on Motor Function in Healthy Participants: A Phase 1, Randomised, Triple-Blind, Dose-Finding Study.CNS drugs · 2026-08-07The Efficacy of Psilocybin Therapy for Depression in Parkinson's DiseaseClinicalTrials.gov · 2026-08-07Open Label Psilocybin Brain Stimulation and Imaging Pilot StudyClinicalTrials.gov · 2026-08-07Correspondence: "Breaking the chains of depression: A systematic review and meta-analysis of psilocybin therapy".Journal of affective disorders · 2026-08-06Psilocybin-assisted therapy for treatment-resistant major depressive disorder in a public healthcare setting: a randomized controlled trial.Nature medicine · 2026-08-06Single Dose Psilocybin for a Post-surgical Trauma Inpatient Population for Pain, Mood, and Opioid Use DisorderClinicalTrials.gov · 2026-08-06Psilocybin for Treatment-Resistant Depression in Autism: a Pilot Trial With Pre-Post Brain and Cognitive Measurement to Understand MechanismClinicalTrials.gov · 2026-08-06An Exploratory Study of Feasibility, Efficacy, and Mechanisms of Mindfulness-Assisted Psychedelic TherapyClinicalTrials.gov · 2026-08-06Mapping excitatory synaptic plasticity evoked by single-dose psilocybin in micebioRxiv · 2026-08-05Role of β-Arrestin2 Signaling in Neuropharmacological Effects of Psychedelic Drugs.ACS chemical neuroscience · 2026-08-05Feasibility Phase 2 Study of Psilocybin-Assisted Therapy for Opioid-Refractory Pain in Patients With Advanced CancerClinicalTrials.gov · 2026-08-05Precision Phenotyping of Behavioral Risk and Response to Electromagnetic and Psychedelic TherapiesClinicalTrials.gov · 2026-08-04Psychedelics and women's mental health: the effects of female sex hormones on psychedelics' efficacy and tolerability.Molecular psychiatry · 2026-08-04Serotonergic psychedelics induce distinct patterns of metabolic activity and covariance within biologically informed rat brain networksNature Communications · 2026-08-03Music for Psilocybin Therapy and the Temporal Arc of Psychedelic ExperienceResearch Square · 2026-08-03Safety and Efficacy of Psilocybin During Anticancer Treatment: A Phase II Trial Secondary Analysis.Journal of pain and symptom management · 2026-08-03Where is the sweet spot for psychedelic-enhanced fear extinction? An integrative quantitative synthesis of dose-effect patterns in rodent models.Journal of psychopharmacology (Oxford, England) · 2026-08-03Psilocybin as a Treatment for Chronic Pain in SmokersClinicalTrials.gov · 2026-08-03Cardiovascular safety of psilocybin in psychiatric practice: a narrative reviewEuropean Journal of Clinical Pharmacology · 2026-08-01From trial to clinic: psilocybin's efficacy in routine treatment-resistant depression.The Lancet regional health. Europe · 2026-08-01Ethical Complexities and Best Practices in Informed Consent Processes for Psilocybin Services: A Qualitative StudyNeuroethics · 2026-08-01In-silico toxicity study of tryptamine, psilocin, psilocybin, N,N-dimethyltryptamine, 5’-methoxy-N,N-dimethyltryptamine and O-acetylpsilocinArchives of Toxicology · 2026-08-01Psilocybin induces stereotyped movements and reduces defensive responding in planarians through 5-hydroxytryptamine mechanismsBehavioural Pharmacology · 2026-08-01Current status and future prospects of research on psilocybin's regulation of neurotransmitters and their receptors related to the pathogenesis of tinnitus.Hearing research · 2026-08-01Anxiety-related platform in zebrafish (Danio rerio) larvae: An integrated analysis of behavioural and molecular assay in drug screening research.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2026-08-01The role of therapeutic alliance in psilocybin treatment for treatment-resistant depression: A post hoc path analysisJournal of Affective Disorders · 2026-08-01A cross-national comparison of nonmedical and medical use of psychedelic drugs in the international cannabis policy study.The International journal on drug policy · 2026-08-01The Experience-Trajectory Framework: Substance-Specific Risk Stratification for Psychedelic Preparation and Aftercare Beyond Set and SettingInternational Journal For Multidisciplinary Research · 2026-07-31