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Contribution of the Serotonin 5-HT2A Receptor to the Therapeutic Effect of Psilocin on Social Behavior Deficits in Mice Repeatedly Exposed to Social Defeat StressNeuropsychopharmacology Reports · 2026-09-01Genome-based optimization of psilocybin and N,N-dimethyltryptamine biosynthetic pathways in E. coli using CRISPR-associated transposasesMetabolic Engineering · 2026-09-01Exploring the In Vitro Effect of Psilocybin on the Composition and Metabolic Activity of Gut Microbiota in Individuals with Severe AnxietyDrugs and Drug Candidates · 2026-08-12Effects of naturalistic psychedelic use on executive functioning: An online survey of lifetime history and recent use in university students.Progress in neuro-psychopharmacology & biological psychiatry · 2026-08-11Circulating MicroRNAs and Their Associations with Neurotrophic, Inflammatory and Glutamate Markers in Healthy VolunteersbioRxiv · 2026-08-10Temporal effects of a single oral dose of psilocybin on plasma circulating miRNAs in healthy young adultsbioRxiv · 2026-08-10A Phase III, Multicentre, Randomised, Double-blind, Controlled Study to Investigate the Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in Participants With Treatment-resistant DepressionClinicalTrials.gov · 2026-08-10Therapeutic potential of classic and non-classic psychedelics in neurodevelopmental disorders: Opportunities and challenges.Pharmacological research · 2026-08-06Psilocybin-assisted therapy for major depressive disorder: Perspective from meta-analysisJournal of Affective Disorders · 2026-08-01A Randomized, Double-Blind, Placebo-Controlled Mechanistic Study to Assess a Single Oral Dose of CYB003 in Participants With Major Depressive Disorder (MDD) and Moderate to Severe AnxietyClinicalTrials.gov · 2026-07-23Longitudinal neural and psychological changes following psilocybin under compassion imagery primingFrontiers in Human Neuroscience · 2026-07-22Integrated 5-HT-TrkB and G protein signaling in serotonergic psychedelic responses.Molecular psychiatry · 2026-07-16Silence is golden: Documenting the speech production of participants and support providers in psilocybin administration sessions for the treatment of post-traumatic stress disorderJournal of Psychopharmacology · 2026-07-16α2-Adrenergic receptor modulates 5-HT2A-mediated behavioral effects of MDMA and psilocybin in miceMolecular Psychiatry · 2026-07-07Acceptability and safety of two sequential doses of psilocybin in bipolar II depression: protocol for an open-label single-arm feasibility studyBMJ Open · 2026-07-01Psilocybin improves novel object recognition in a rat model of Fragile X Syndrome through the modulation of the BDNF/TrkB signaling pathway.Neuropsychopharmacology: official publication of the American College of Neuropsychopharmacology · 2026-07-01The relevance of the 5HT2A-mGlu2 heterodimer in explaining the clinical ambivalence of psilocybinRevista de Neuro-Psiquiatría · 2026-06-30A Pilot Mechanistic RCT of Psilocybin With Mindfulness-based Therapy vs Support for Posttraumatic Stress Disorder (PTSD)ClinicalTrials.gov · 2026-06-25Mechanistic insights toward dissociating therapeutic from psychedelic effects: bridging the gap between psychedelic research and mental health careTranslational Psychiatry · 2026-06-23A Double Blind, Randomized Trial Investigating the Safety, Feasibility, and Mechanisms of Psychedelics in Healthy Older Adults With Low Well-being as Moderated by Biomarkers for Preclinical Alzheimer's DiseaseClinicalTrials.gov · 2026-06-08EE127 A REVIEW OF HEALTH ECONOMIC ANALYSES OF PSILOCYBIN, MIDOMAFETAMINE(MDMA), AND KETAMINE-BASED TREATMENTS FOR MENTAL HEALTH CAREValue in Health · 2026-06-01Meaning-Centered Psychotherapy for Psilocybin-Assisted Therapy Among Patients with Advanced Cancer and Depression: Rationale and Preliminary Evaluation of MCP-PSIL.Psychedelic medicine (New Rochelle, N.Y.) · 2026-06-01Therapeutic advances in fibromyalgia: one year in review 2026.Clinical and experimental rheumatology · 2026-06-01PsiConnect: Multimodal Neuroimaging of Context-Dependent Brain and Behaviour Dynamics under PsilocybinScientific Data · 2026-05-21Exploring the Safety, Acceptability, and Efficacy of Psilocybin Among Non-Small Cell Lung Cancer Patients With Major Depressive Disorder: A Proof-of-Concept Trial (DREAM LUNG STUDY)ClinicalTrials.gov · 2026-05-14Efficacy and Safety of a Single Dose of Psilocybin for Chronic Suicidal IdeationThe Journal of Clinical Psychiatry · 2026-05-13Psilocybin in the Treatment of Cocaine Use DisorderJAMA Network Open · 2026-05-07Pure psilocybin reduces reward-associated preference while mushroom extract shows transient exploratory effects in ratsRevSALUS - Revista Científica da Rede Académica das Ciências da Saúde da Lusofonia · 2026-05-01Cytochrome P450 Inhibition by Psilocybin and Psilocin: A Combined Molecular Dynamics and Enzymatic Screening StudyRevSALUS - Revista Científica da Rede Académica das Ciências da Saúde da Lusofonia · 2026-05-01Effects of psychedelic use on authoritarian attitudes revisited.Journal of psychopharmacology (Oxford, England) · 2026-05-01Associations between psychedelic use and migraine history in Swedish twins.Journal of psychopharmacology (Oxford, England) · 2026-05-01Specific and Multi-Product Clade I and Clade IV Sesquiterpene Synthases Contribute to the Psilocybe cubensis Volatilome.Chembiochem: a European journal of chemical biology · 2026-04-28157. Opposing 5-HT Receptors Modulate Psilocybin's Action on Dendritic Calcium DynamicsBiological Psychiatry · 2026-04-25Impact of psilocybin and Psilocybe cubensis extract on gut microbiota in Wistar Han ratsScience Letters · 2026-04-17Psilocybin and Psilocybe cubensis extract exhibit divergent behavioural and toxicological effects in ratsScience Letters · 2026-04-17CAPSI - Cancer Related Major Depression Treated With a Single Dose of Psilocybin: A Multicenter Randomized Placebo Controlled Double Blind Clinical TrialClinicalTrials.gov · 2026-04-13Hallucinogenic Therapy in Alzheimer's Disease targeting Mitochondria-Associated Membranes.Neuroscience · 2026-04-06An international mega-analysis of psychedelic drug effects on brain circuit function.Nature medicine · 2026-04-01Integrated 5-HT -TrkB and G protein signaling in serotonergic psychedelic responses.bioRxiv: the preprint server for biology · 2026-03-23Psilocybin retail stores in Canada: Changes in availability, commercialization, and geographic distributionCanadian Journal of Public Health · 2026-03-19Examining the Safety and Clinical Efficacy of Psilocybin Therapy for Veterans With PTSD: An Open-Label Proof-of-Concept TrialClinicalTrials.gov · 2026-03-04Psilocin as a Broad Inhibitor of CYP450 Enzymes: Integrated In Vitro and In Silico EvidenceInstituto Politécnico do Porto · 2026-02-25Pilot study of psilocybin in patients with post-treatment lyme diseaseScientific Reports · 2026-02-25Acute psilocin increased cortical activity in ratFrontiers in Neuroscience · 2026-02-04Approved and Pipeline Pharmacological Interventions for Eating Disorders (2010-2025): 15 Years of Progress (or Lack Thereof).CNS drugs · 2026-02-01Low, non-psychedelic doses of psilocybin as a novel treatment for MASLD, obesity and type 2 diabetes via 5-HT2B receptor-dependent mechanismsRepository for Publications and Research Data (ETH Zurich) · 2026-01-20Psilocybin for Treatment-Resistant OCD: A Randomized Controlled TrialPsyArXiv · 2026-01-15Optimization of Psilocybin Extraction from Psilocybe cubensis Mushrooms and Characterization of the Fungal ExtractJournal of the Brazilian Chemical Society · 2026-01-01Temporal effects of a single oral dose of psilocybin on plasma circulating miRNAs in humansNeuroscience Applied · 2026-01-01Attitudes Toward Psychedelic Treatments by Individuals With Histories of Substance Use or Psychiatric Disorders: A Survey Study.Journal of addiction medicine · 2026-01-015 Years of bipolar disorder conversations on Reddit: Methods, key topics and future directions.PloS one · 2026-01-01Psychedelic-assisted therapy: a survey on the clinical methods of Swiss physicians.Therapeutic advances in psychopharmacology · 2026-01-01Effects of LSD and Psilocybin on Heart Rate in Patients Receiving Psychedelic Treatment for Depressive and Anxiety Disorders: A Retrospective Observational StudyPsychology International · 2025-12-19Which Psychotherapy Model Should be Used in Psilocybin Treatment for Depression?Trends in psychiatry and psychotherapy · 2025-12-17The Psychedelic Psilocin Suppresses Activity of Central Amygdala Corticotropin-Releasing Factor Receptor 1 Neurons and Decreases Ethanol Drinking in Female MiceThe Journal of Neuroscience · 2025-12-10Psilocybin Maintains Better Brain Function in an Alzheimer’s Disease Model with Reduced Neuroinflammation and Improved Hippocampal NeurogenesisAlzheimer's & dementia: the journal of the Alzheimer's Association · 2025-12-01Novel qNMR Method to Quantify Psilocybin and Psilocin in Psychedelic MushroomsACS Omega · 2025-11-25Zalsupindole is a Nondissociative, Nonhallucinogenic Neuroplastogen with Therapeutic Effects Comparable to Ketamine and Psychedelics.ACS chemical neuroscience · 2025-11-19Single-dose (10 mg) psilocybin reduces symptoms in adults with obsessive-compulsive disorder: A pharmacological challenge study.Comprehensive psychiatry · 2025-10-01The polypharmacology of psychedelics reveals multiple targets for potential therapeutics.Neuron · 2025-10-01Endocannabinoids, depression, and treatment resistance: Perspectives on effective therapeutic interventions.Psychiatry research · 2025-10-01[Role of psychedelics in psychiatry: a true therapeutic revolution or a trend?].La Revue du praticien · 2025-10-013642 Down the rabbit hole: case reports of a hallucinogen-induced disorder of neuroperceptionPoster Abstracts · 2025-09-30Psychedelics Relax Priors and Reshape Orbitofrontal DynamicsbioRxiv · 2025-09-19Psilocybin-Assisted Psychotherapy for Chronic Somatoform Pain Disorder: A Case ReportPsychoactives · 2025-09-01A critical evaluation of psilocybin-assisted therapy protocol components from clinical trial patients, facilitators, and caregivers.Psychotherapy (Chicago, Ill.) · 2025-09-01Lifetime classic psychedelic use and headaches: A cross-sectional study.Journal of psychopharmacology (Oxford, England) · 2025-09-01Severe Rhabdomyolysis With Stage 3 Acute Kidney Injury After Ayahuasca Use Managed Without Renal Replacement Therapy: A Case Report.Cureus · 2025-09-01Substance Abuse and Cognitive Decline: The Critical Role of Tau Protein as a Potential Biomarker.International journal of molecular sciences · 2025-08-07Psilocybin triggers an activity-dependent rewiring of large-scale cortical networksbioRxiv · 2025-08-06Development and validation of a HPLC-DAD method for determining the content of tryptamines in methanolic extracts of fruiting bodies of mushrooms belonging to species of the Psilocybe genus.Talanta · 2025-08-01Stronger visual surround suppression under psilocybin: A psychophysical and EEG pilot studyJournal of Vision · 2025-07-15Clade III Synthases Add Cyclic and Linear Terpenoids to the Psilocybe Metabolome.Chembiochem: a European journal of chemical biology · 2025-07-11Psilocybin treatment extends cellular lifespan and improves survival of aged mice.npj aging · 2025-07-08The therapeutic effects of psychedelics for opioid use disorder: A systematic review of clinical studies.Psychiatry research · 2025-06-01Psilocybin's lasting action requires pyramidal cell types and 5-HT receptors.Nature · 2025-06-01Therapeutic emergence of dissociated traumatic memories during psilocybin treatment for anorexia nervosa.Journal of eating disorders · 2025-05-26Ergotamine enhances circadian amplitude and diurnally mitigates nitroglycerin-induced mechanical hypersensitivity.The journal of headache and pain · 2025-05-23Psilocybin-gestützte Therapie von Depression, Angst und Suchtstörungen: Neurobiologische Grundlagen und klinische AnwendungNervenheilkunde · 2025-05-01ALSUntangled #77: Psilocybin.Amyotrophic lateral sclerosis & frontotemporal degeneration · 2025-05-01Psilocybin as a Tool in the Management of Palliative Care: An Historical, Pharmacological, and Clinical ApproachPreprints.org · 2025-04-1058. Acute Behavioral Effects of Psilocybin and Its Pharmacokinetics in Nonhuman PrimatesBiological Psychiatry · 2025-04-09A Rapid Review of Psychedelic-Assisted Therapy in the Context of Palliative Care.Journal of hospice and palliative nursing: JHPN: the official journal of the Hospice and Palliative Nurses Association · 2025-04-01A Rapid Review of Psychedelic-Assisted Therapy in the Context of Palliative Care.Journal of hospice and palliative nursing: JHPN: the official journal of the Hospice and Palliative Nurses Association · 2025-04-01Psilocybin Dispensaries and Online Health Claims in Canada.JAMA network open · 2025-04-01Psychedelics Align Brain Activity with ContextbioRxiv · 2025-03-11Exploring Public Sentiments of Psychedelics Versus Other Substances: A Reddit-Based Natural Language Processing StudyPsyArXiv · 2025-03-07Exploring Public Sentiments of Psychedelics Versus Other Substances: A Reddit-Based Natural Language Processing StudyPsyArXiv · 2025-03-07Anhedonia: Current and future treatments.PCN reports: psychiatry and clinical neurosciences · 2025-03-01Uncovering Psychedelics: From Neural Circuits to Therapeutic Applications.Pharmaceuticals (Basel, Switzerland) · 2025-01-19Clinical use of psilocybin in mental disorders:: a bibliometric analysis in Scopus and Web of ScienceDialnet (Universidad de la Rioja) · 2025-01-01Study Protocol for 'PsilOCD: A Pharmacological Challenge Study Evaluating the Effects of the 5-HT2A Agonist Psilocybin on the Neurocognitive and Clinical Correlates of Compulsivity'.Cureus · 2025-01-01Correction: Study Protocol for 'PsilOCD: A Pharmacological Challenge Study Evaluating the Effects of the 5-HT2A Agonist Psilocybin on the Neurocognitive and Clinical Correlates of Compulsivity'.Cureus · 2025-01-01Roadmap for Equitable Access and Responsible Use of Psilocybin-Assisted Psychotherapy in Palliative Care.Palliative medicine reports · 2025-01-01A landscape analysis of psychedelic retreat organizations advertising online.PloS one · 2025-01-01The revival of psilocybin between scientific excitement, evidence of efficacy, and real-world challenges.CNS spectrums · 2024-12-01Pattern of psychedelic substance use: a comparison between populations in Spain and South America using the Psychedelic Use Scale (PUS)Current Psychology · 2024-11-21Psychedelic-assisted therapy for treating anxiety, depression, and existential distress in people with life-threatening diseases.The Cochrane database of systematic reviews · 2024-09-12Psychedelic-assisted therapy for palliative care within a home treatment setting: A case report.Clinical case reports · 2024-09-01Psilocybin Therapy for Females With Anorexia Nervosa: A Phase 1, Open-Label Feasibility Study.Focus (American Psychiatric Publishing) · 2024-07-01[Psilocybin-Assisted Treatment of Depression, Anxiety and Substance use Disorders: Neurobiological Basis and Clinical Application].Fortschritte der Neurologie-Psychiatrie · 2024-06-01Structural pharmacology and therapeutic potential of 5-methoxytryptamines.Nature · 2024-06-01THU-285 Lownonpsychedelic dosed of psilocybin for the therapy of MASLDJournal of Hepatology · 2024-05-31Psilocybin, peyote, mescaline, and lysergic acid diethylamide (LSD) use in a nationally representative population by cancer history.Journal of Clinical Oncology · 2024-05-31Psilocybe cubensis extract potently prevents fear memory recall and freezing behavior in short- but not long-term in a rat model of posttraumatic stress disorder.Behavioral neuroscience · 2024-04-01UK medical students' self-reported knowledge and harm assessment of psychedelics and their application in clinical research: a cross-sectional study.BMJ open · 2024-03-14Development of a digital intervention for psychedelic preparation (DIPP).Scientific reports · 2024-02-19Set and setting predict psychopathology, wellbeing and meaningfulness of psychedelic experiences: a correlational study.Expert review of clinical pharmacology · 2024-01-01Development and validation of a sensitive LC-MS-MS method to quantify psilocin in authentic oral fluid samplesJournal of Analytical Toxicology · 2023-12-12Development of a Digital Intervention for Psychedelic Preparation (DIPP): a theory- and person-centred approachPsyArXiv · 2023-11-22Development of a Digital Intervention for Psychedelic Preparation (DIPP): a theory- and person-centred approachPsyArXiv · 2023-11-22A "Magic Mushroom" Multi-Product Sesquiterpene Synthase.Chembiochem: a European journal of chemical biology · 2023-11-02Clinical specificity profile for novel rapid acting antidepressant drugs.International clinical psychopharmacology · 2023-09-01Repeated low doses of psilocybin increase resilience to stress, lower compulsive actions, and strengthen cortical connections to the paraventricular thalamic nucleus in rats.Molecular psychiatry · 2023-09-01TMS-EEG and resting-state EEG applied to altered states of consciousness: oscillations, complexity, and phenomenology.iScience · 2023-05-19Italian psychedelic therapies of the past century: An historical overviewDrug Science Policy and Law · 2023-01-01Therapeutic mechanism of psilocybin in the treatment of depression and other psychiatric disorders.Neuroscience Applied · 2023-01-01Altered states of leadership: mindfulness meditation, psychedelic use, and leadership development.Frontiers in psychology · 2023-01-01Naturalistic psilocybin use is associated with persisting improvements in mental health and wellbeing: results from a prospective, longitudinal survey.Frontiers in psychiatry · 2023-01-01Psilocybin for Depression: From Credibility to Feasibility, What's Missing?Pharmaceuticals (Basel, Switzerland) · 2022-12-31Use of plant-based hallucinogens and dissociative agents: U.S. Time Trends, 2002-2019.Addictive behaviors reports · 2022-12-01Single-Dose Psilocybin for a Treatment-Resistant Episode of Major Depression.The New England journal of medicine · 2022-11-03Psilocybin mushrooms for psychological and existential distress: Treatment for a patient with palliative lung cancer.Canadian family physician Medecin de famille canadien · 2022-11-01Cystathionine Gamma-Lyase Regulate Psilocybin Biosynthesis in Mushroom via Amino Acid Metabolism Pathways.Journal of fungi (Basel, Switzerland) · 2022-08-18Psilocybin and the Meaning Response: Exploring the Healing Process in a Retreat Setting in JamaicaAnthropology of Consciousness · 2022-08-14Effects of ketamine optical isomers, psilocybin, psilocin and norpsilocin on time estimation and cognition in ratsPsychopharmacology · 2022-06-01Safety issues of psilocybin and LSD as potential rapid acting antidepressants and potential challenges.Expert opinion on drug safety · 2022-06-01P450. Pilot Study Evaluation of Psilocybin Therapy for Anorexia Nervosa: Safety, Acceptability, and Preliminary EfficacyBiological Psychiatry · 2022-04-27Psychedelics and Hallucinogens in Psychiatry: Finding New Pharmacological Targets.Current topics in medicinal chemistry · 2022-01-01The effects of psilocybin on cognitive and emotional functions in healthy participants: Results from a phase 1, randomised, placebo-controlled trial involving simultaneous psilocybin administration and preparation.Journal of psychopharmacology (Oxford, England) · 2022-01-01[Treatment-resistant depression. From classification to new therapies.].Rivista di psichiatria · 2022-01-01P.0729 Highlights of psychedelic history and current research on psilocybin application for treatment of depression - a comprehensive literature reviewEuropean Neuropsychopharmacology · 2021-12-01Psilocybin induces rapid and persistent growth of dendritic spines in frontal cortex in vivo.Neuron · 2021-08-18Serotonin Heteroreceptor Complexes and Their Integration of Signals in Neurons and Astroglia-Relevance for Mental Diseases.Cells · 2021-07-27Safer Tripping: Serotonergic Psychedelics and Drug Checking. Submission and Detection Rates, Potential Harms, and Challenges for Drug AnalysisCurrent Addiction Reports · 2021-07-26A dynamic and multilocus metabolic regulation strategy using quorum-sensing-controlled bacterial small RNA.Cell reports · 2021-07-20A utilização terapêutica da psilocibina como coadjuvante no tratamento do transtorno depressivo maior: uma revisão narrativa de literatura / The therapeutic use of psilocybin as an adjunct in the treatment of major depressive disorder: a narrative literature reviewBrazilian Journal of Health Review · 2021-05-03Effects of Psilocybin on Suicidal Ideation in Patients With Life-Threatening CancerBiological Psychiatry · 2021-04-27Acute and Sustained Reductions in Loss of Meaning and Suicidal Ideation Following Psilocybin-Assisted Psychotherapy for Psychiatric and Existential Distress in Life-Threatening Cancer.ACS pharmacology & translational science · 2021-04-09Effects of psilocybin-assisted therapy on treatment-resistant depressionEuropean Psychiatry · 2021-04-01Development of the Psychological Insight Questionnaire among a sample of people who have consumed psilocybin or LSD.Journal of psychopharmacology (Oxford, England) · 2021-04-01Associations between lifetime classic psychedelic use and markers of physical health.Journal of psychopharmacology (Oxford, England) · 2021-04-01Complete mitochondrial genome sequence of.Mitochondrial DNA. Part B, Resources · 2021-03-18What is the clinical evidence on psilocybin for the treatment of psychiatric disorders? A systematic review.Porto biomedical journal · 2021-01-01Effects of Ayahuasca on Personality: Results of Two Randomized, Placebo-Controlled Trials in Healthy Volunteers.Frontiers in psychiatry · 2021-01-01Self-Reported Illicit Drug Use Among Norwegian University and College Students. Associations With Age, Gender, and Geography.Frontiers in psychiatry · 2020-01-01P.228 The polypharmacological profile of psilocybin and potential behavioural effects of very low dosesEuropean Neuropsychopharmacology · 2019-12-01New Psychoactive Substances (NPS), Psychedelic Experiences and Dissociation: Clinical and Clinical Pharmacological IssuesCurrent Addiction Reports · 2019-04-22Natural speech algorithm applied to baseline interview data can predict which patients will respond to psilocybin for treatment-resistant depression.Journal of affective disorders · 2018-04-01[Three cases of acute serotonin syndrome due to psilocybin mushroom poisoning].Chudoku kenkyu: Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology · 2016-03-01MAGIC MUSHROOM AND ITS EFFECTIVENESSInternational Journal of Pharma and Bio Sciences · 2016-01-01Recreational use, analysis and toxicity of tryptamines.Current neuropharmacology · 2015-01-01The psychedelic state induced by ayahuasca modulates the activity and connectivity of the default mode network.PloS one · 2015-01-01Magic truffles or Philosopher's stones: a legal way to sell psilocybin?Drug testing and analysis · 2013-03-01Spirituality and Hallucinogen Use: Results from a Pilot Study among College StudentsInternational Journal of Transpersonal Studies · 2012-06-30Chemical Constituents of Gymnopilus spectabilis and Their Antioxidant Activity.Mycobiology · 2008-03-01Morphological and chemical analysis of magic mushrooms in Japan.Forensic science international · 2003-12-17The pharmacology of psilocybin.Addiction biology · 2002-10-01ChemInform Abstract: The Chemistry of Indoles. Part 109. Synthetic Studies of Psilocin Analogues Having Either a Formyl Group or Bromine Atom at the 5- or 7-Position.ChemInform · 2002-07-23Synthetic Studies of Psilocin Analogs Having Either a Formyl Group or Bromine Atom at the 5- or 7-Position.Chemical and Pharmaceutical Bulletin · 2002-01-01H-D Exchange of Psilocin and Its AnalogsHETEROCYCLES · 1999-01-01A New Synthesis of PsilocinHETEROCYCLES · 1999-01-01The quantitation of psilocybin in hallucinogenic mushrooms using high performance liquid chromatography.Journal of forensic sciences · 1983-10-01Isolation of Psilocybin From Psilocybe argentipes and Its Determination in Specimens of Some MushroomsJournal of Natural Products · 1981-05-01