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Chronic psilocin microdosing produces limited behavioral effects and does not enhance neurogenesis in ratsPharmacology Biochemistry and Behavior · 2026-10-01Single-crystal structure determination of psilocybin after dehydrationActa Crystallographica Section C Structural Chemistry · 2026-09-01A Phase III, Multicentre, Randomised, Double-blind, Controlled Study to Investigate the Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in Participants With Treatment-resistant DepressionClinicalTrials.gov · 2026-08-10A Phase III, Multicentre, Randomised, Double-blind, Placebo-controlled Study to Investigate the Efficacy, Safety, and Tolerability of COMP360 in Participants With Treatment-resistant DepressionClinicalTrials.gov · 2026-08-10Impact of Psilocybin on Motor Function in Healthy Participants: A Phase 1, Randomised, Triple-Blind, Dose-Finding Study.CNS drugs · 2026-08-07A Phase 3, Randomized, Double-Blind, Multicenter Study to Evaluate the Efficacy, Safety, and Tolerability of Psilocybin in Adults With Major Depressive Disorder (MDD)ClinicalTrials.gov · 2026-07-23Psychedelics in treatment-resistant depression: a comprehensive review of mechanisms, clinical evidence, and recommendations.Neuropsychiatrie: Klinik, Diagnostik, Therapie und Rehabilitation: Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2026-06-302 x 2 Factorial, Double-blind, Randomized Trial of 'Set and Setting': a Translational Study in Healthy VolunteersClinicalTrials.gov · 2026-06-04Psilocybin: Chemical Foundations and Emerging Therapeutic PotentialMini-Reviews in Medicinal Chemistry · 2026-06-01Long-Term Efficacy of Psilocybin with Adjunct Psychotherapy in Treatment-Resistant Major Depression: 6- and 12-Month Naturalistic Follow-Up of a Phase 2b TrialPsychotherapy and Psychosomatics · 2026-05-27Mescaline Alters Cerebellar Function, Global Connectivity, and Frequency-Selective Acoustic Gating: A BOLD fMRI Study in Awake Rats.Neuroscience bulletin · 2026-05-21A Pilot Mechanistic Study of Psilocybin-Assisted Therapy as a Treatment for DepressionClinicalTrials.gov · 2026-05-20Exploring new avenues: Psychedelic-assisted therapy for young people.British journal of clinical pharmacology · 2026-05-08Prevalence and Correlates of Past-Year Psilocybin Use in the U.S., 2024, USAAJPM Focus · 2026-05-01Efficacy and Safety of Psilocybin in Treatment-Resistant Major DepressionJAMA Psychiatry · 2026-05-01Fusing Specialized Surveys of Rare Populations to Larger Surveys for Generalized Inference: Cross-Sectional Survey Study.Journal of medical Internet research · 2026-04-27Psilocybin Trends in States That Decriminalized UseJAMA · 2026-04-14CAPSI - Cancer Related Major Depression Treated With a Single Dose of Psilocybin: A Multicenter Randomized Placebo Controlled Double Blind Clinical TrialClinicalTrials.gov · 2026-04-13Clinical Characteristics of Emergency Visits Related to Recreational Psychedelic Use.Community mental health journal · 2026-04-01Associations Between Psilocybin Use Motives and Cognitive, Affective, and Behavioural Self-StigmaSubstance Use & Misuse · 2026-03-28Psychedelic Terminology Preference in the 2024 National Survey Investigating Hallucinogenic Trends (NSIHT).Journal of psychoactive drugs · 2026-03-16Design, Synthesis, and Pharmacokinetic Profiling of Fluorinated Reversible N -Alkyl Carbamate Derivatives of Psilocin for Sub-Hallucinogenic Brain ExposureJournal of Medicinal Chemistry · 2026-02-12India's Unique Legal Framework for Psilocybin Mushroom Research: An Unprecedented Opportunity in Psychiatric Therapeutics.Indian journal of psychological medicine · 2026-02-05Corrigendum to "The role of the psychedelic experience in psilocybin treatment for treatment-resistant depression" [Journal of Affective Disorders, Volume 372 (2025), Pages 523-532].Journal of affective disorders · 2026-01-15The impact of COMP360 psilocybin on anhedonia: post-hoc analyses from a phase IIb randomised controlled trialNeuroscience Applied · 2026-01-01The Relationship Between Participant Pretreatment Clinical Presentation and the Quality of Psilocybin Experience: A Retrospective Analysis.Journal of clinical psychopharmacology · 2026-01-01A Randomised, Triple-Blind, Dose-Finding Study of the Impact of Psilocybin on Motor Function in Healthy ParticipantsmedRxiv · 2025-12-23Three Cases of Depersonalization/Derealization Disorder Related to the Use of Classic PsychedelicsSUCHT - Zeitschrift für Wissenschaft und Praxis / Journal of Addiction Research and Practice · 2025-12-01Psilocybin-assisted physiotherapy for refractory motor functional neurological disorder: protocol for a randomised dose-comparison pilot study.Acta neuropsychiatrica · 2025-11-04Precision Functional Brain Mapping to Understand the Mechanisms of PsilocybinClinicalTrials.gov · 2025-10-31Structure-Guided Design of Novel 5-HT Partial Agonists as Psychedelic Analogues with Antidepressant Effects.Journal of medicinal chemistry · 2025-10-23Analysis of Serotonin in Caenorhabditis Elegans Subjected to Micro-Dosing with Psilocybin| Iris PublishersInsights in Chemistry and Biochemistry · 2025-10-15Understanding psilocybin mushrooms and aiding in setting standards for a burgeoning industry in JamaicaPhytochemistry Letters · 2025-10-01B-302 Psychedelics and Dissociative Anesthetics: Concentrations in Suspected Impaired Driving Investigations, 2024Clinical Chemistry · 2025-09-30In Vitro Psilocybin Synthesis by Co-Immobilized Enzymes.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025-05-22Synthesis and In Vitro Profiling of Psilocin Derivatives: Improved Stability and Synthetic PropertiesJournal of Medicinal Chemistry · 2025-04-10Sporadic use of classic psychedelics and neuropsychological performance: A cross-sectional analysis.Progress in neuro-psychopharmacology & biological psychiatry · 2025-04-02Moderating factors in psilocybin-assisted treatment affecting mood and personality: A naturalistic, open-label investigation.Psychopharmacology · 2025-04-01Results From a Long-Term Observational Follow-Up Study of a Single Dose of Psilocybin for a Treatment-Resistant Episode of Major Depressive Disorder.The Journal of clinical psychiatry · 2025-03-03The role of the psychedelic experience in psilocybin treatment for treatment-resistant depression.Journal of affective disorders · 2025-03-01Serotonergic Psychedelics Rapidly Modulate Evoked Glutamate Release in Cultured Cortical Neurons.Journal of neurochemistry · 2025-03-01Pain and Perception: Exploring Psychedelics as Novel Therapeutic Agents in Chronic Pain Management.Current pain and headache reports · 2025-01-07Geographical Differences in Self-Reported Past 12-Month Drug Use: Results from the NDEWS Rapid Street Reporting, 2021-2023.Substance use & misuse · 2025-01-01Psilocybin alleviates high-glucose and high-lipid-induced skin aging in BJ5Ta fibroblasts.Biochemistry and cell biology = Biochimie et biologie cellulaire · 2025-01-01Psychedelic Microdosing among Young Adults from Southern California.Journal of psychoactive drugs · 2025-01-01Neuropsychological profiles of patients suffering from hallucinogen persisting perception disorder (HPPD): A comparative analysis with psychedelic-using and non-using controls.Scientific reports · 2024-12-31Worsening suicidal ideation and prolonged adverse event following psilocybin administration in a clinical setting: case report and thematic analysis of one participant's experience.BJPsych open · 2024-12-10The impact of antidepressant discontinuation prior to treatment with psilocybin for treatment-resistant depression.Journal of psychiatric research · 2024-12-01The Afterglow Inventory (AGI) - validation of a new instrument for measuring subacute effects of classic serotonergic psychedelicsPsyArXiv · 2024-10-22Current Trends in Psychedelic Science: Integrating Modified Lysergic Acid Derivatives and Psilocybin in Modern Medicine.ACS medicinal chemistry letters · 2024-09-12Advancements in Psychoactive Alkaloid Delivery, Neuroenhancement, and Psychedelic Therapies: Exploring the Frontiers of Modern Pharmacology.ACS medicinal chemistry letters · 2024-06-13Discovery and Structure-Activity Relationships of 2,5-Dimethoxyphenylpiperidines as Selective Serotonin 5-HT Receptor Agonists.Journal of medicinal chemistry · 2024-05-09Psychedelics for alzheimer's disease-related dementia: Unveiling therapeutic possibilities and pathways.Ageing research reviews · 2024-04-01Psychedelics: reconnecting the brain to heal the mindThe Biochemist · 2024-03-25Synthesis and bioactivity of psilocybin analogues containing a stable carbon-phosphorus bond.RSC medicinal chemistry · 2024-03-20Scanning the new frontier of mental health: psychedelic brain imagingThe Biochemist · 2024-03-14Established sensitization of ethanol-induced locomotor activity is not reversed by psilocybin or the 5-HT receptor agonist TCB-2 in male DBA/2J mice.Pharmacology, biochemistry, and behavior · 2024-02-01Psychedelics for mental health: a biochemical perspectiveThe Biochemist · 2024-01-19Investigational COMP360 psilocybin treatment for treatment-resistant depression: assessing altered states of consciousnessNeuroscience Applied · 2024-01-01Psilocybin and Motor Function: A Triple-Blind, Dose-Finding Study in Healthy Participants.Psychiatric research and clinical practice · 2024-01-01A cane toad (Rhinella marina) N-methyltransferase converts primary indolethylamines to tertiary psychedelic aminesJournal of Biological Chemistry · 2023-09-09Addressing the Current Knowledge and Gaps in Research Surrounding Lysergic Acid Diethylamide (LSD), Psilocybin, and Psilocin in Rodent ModelsCurrent Topics in Medicinal Chemistry · 2023-09-01Psilocybin for treatment resistant depression in patients taking a concomitant SSRI medication.Neuropsychopharmacology: official publication of the American College of Neuropsychopharmacology · 2023-09-01A Brief Review on the Potential of Psychedelics for Treating Alzheimer's Disease and Related Depression.International journal of molecular sciences · 2023-08-07Psilocybin for the treatment of anorexia nervosa.Nature medicine · 2023-08-01The Efficacy and Tolerability of Psilocybin in Participants With Treatment-Resistant Depression: a Phase 2, Randomized Feasibility StudyClinicalTrials.gov · 2023-07-27Improvement in Depression Symptoms Measured by Montgomery-Åsberg Depression Rating Scale and Quick Inventory of Depressive Symptomatology-Self Rated Items after Randomised Double-blind COMP360 Psilocybin Therapy for Treatment-resistant DepressionEuropean psychiatry: the journal of the Association of European Psychiatrists · 2023-07-19Introduction to the chemistry and pharmacology of psychedelic drugsAustralian Journal of Chemistry · 2023-07-04In vivo mapping of pharmacologically induced functional reorganization onto the human brain's neurotransmitter landscape.Science advances · 2023-06-16In silico characterization of the psilocybin biosynthesis pathway.Computational biology and chemistry · 2023-06-01A review of psilocybin: chemistry, clinical uses and future research directionsAustralian Journal of Chemistry · 2023-05-16The Safety and Efficacy of Psilocybin in Participants With Treatment Resistant DepressionClinicalTrials.gov · 2023-04-24Single-dose psilocybin for a treatment-resistant episode of major depression: Impact on patient-reported depression severity, anxiety, function, and quality of life.Journal of affective disorders · 2023-04-14The Theoretical Description for Psilocin Electrochemical Determination over Cobalt OxyhydroxideOrbital: The Electronic Journal of Chemistry · 2023-04-06Psychedelics for Medicinal Use: How Will This Alter the Collective Laboratory Consciousness?Clinical Chemistry · 2023-03-07Matrix-assisted laser-desorption/ionization-mass spectrometric imaging of psilocybin and its analogues in psychedelic mushrooms using a cesium chloride-coated target plate.Analytical and bioanalytical chemistry · 2023-02-01SV2A Marker of Synaptogenesis in a Clinical Trial of Psilocybin for DepressionClinicalTrials.gov · 2023-01-30The safety and efficacy of COMP360 psilocybin therapy in treatment-resistant depression: results from a long-term observational follow-up studyNeuroscience Applied · 2023-01-01Withdrawal of antidepressants does not impact the efficacy of COMP360 psilocybin therapy: results from a phase IIb randomised controlled trialNeuroscience Applied · 2023-01-01Single-Dose Psilocybin for a Treatment-Resistant Episode of Major Depression.The New England journal of medicine · 2022-11-03Conformational Landscape and Properties of Psilocybin: A Computational ApproachChemistrySelect · 2022-10-04Mapping Pharmacologically-induced Functional Reorganisation onto the Brain’s Neurotransmitter LandscapebioRxiv · 2022-07-13From psychiatry to neurology: Psychedelics as prospective therapeutics for neurodegenerative disorders.Journal of neurochemistry · 2022-07-01Molecular insights into psychedelic drug action.Journal of neurochemistry · 2022-07-01Combining FTIR-ATR and OPLS-DA methods for magic mushrooms discriminationForensic Chemistry · 2022-04-08Crystallographic hallucinations.Acta crystallographica. Section C, Structural chemistry · 2022-02-01The efficacy of COMP360 psilocybin therapy in treatment-resistant depression: exploratory results from a phase IIb randomised controlled trialNeuroscience Applied · 2022-01-01The safety and efficacy of COMP360 psilocybin therapy in treatment-resistant depression: results from a phase IIb randomised controlled trialNeuroscience Applied · 2022-01-01Psychedelics and Hallucinogens in Psychiatry: Finding New Pharmacological Targets.Current topics in medicinal chemistry · 2022-01-01Psilocybin: crystal structure solutions enable phase analysis of prior art and recently patented examples.Acta crystallographica. Section C, Structural chemistry · 2022-01-01The effects of psilocybin on cognitive and emotional functions in healthy participants: Results from a phase 1, randomised, placebo-controlled trial involving simultaneous psilocybin administration and preparation.Journal of psychopharmacology (Oxford, England) · 2022-01-01Methodological challenges in psychedelic drug trials: Efficacy and safety of psilocybin in treatment-resistant major depression (EPIsoDE) - Rationale and study design.Neuroscience applied · 2022-01-01P.0421 Efficacy and safety of psilocybin in treatment-resistant major depression (EPIsoDE) - study design, rationale and current statusEuropean Neuropsychopharmacology · 2021-12-01Testing human hair after magic mushrooms abuse by LC-MS/MS: Pitfalls and limitationsForensic Chemistry · 2021-09-20Structure Elucidation and Spectroscopic Analysis of Chromophores Produced by Oxidative Psilocin DimerizationChemistry - A European Journal · 2021-08-19Safer Tripping: Serotonergic Psychedelics and Drug Checking. Submission and Detection Rates, Potential Harms, and Challenges for Drug AnalysisCurrent Addiction Reports · 2021-07-26Use and abuse of dissociative and psychedelic drugs in adolescence.Pharmacology, biochemistry, and behavior · 2021-04-01The Psilocin (4-hydroxy-N,N-dimethyltryptamine) and Bufotenine (5-hydroxy-N,N-dimethyltryptamine) Case: Ensuring the Correct Isomer has Been IdentifiedJournal of Forensic Sciences · 2020-09-01Scalable Hybrid Synthetic/Biocatalytic Route to Psilocybin.Chemistry (Weinheim an der Bergstrasse, Germany) · 2020-07-02Simultaneous Production of Psilocybin and a Cocktail of β-Carboline Monoamine Oxidase Inhibitors in "Magic" Mushrooms.Chemistry (Weinheim an der Bergstrasse, Germany) · 2020-01-13Production Options for Psilocybin: Making of the Magic.Chemistry (Weinheim an der Bergstrasse, Germany) · 2019-01-18Microcrystal Tests for the Identification of Illicit Drugs: Phencyclidine, Pseudoephedrine, and PsilocinThe Microscope · 2019-01-01Sub-Acute Effects of Psilocybin on Empathy, Creative Thinking, and Subjective Well-Being.Journal of psychoactive drugs · 2019-01-01The Utility of Psilocybin in Managing Anxiety and Depression in Cancer PatientsBiochemistry and Molecular Biology Education · 2018-08-01Biocatalytic Production of Psilocybin and Derivatives in Tryptophan Synthase-Enhanced Reactions.Chemistry (Weinheim an der Bergstrasse, Germany) · 2018-07-17[Psychotherapy with Adjuvant use of Serotonergic Psychoactive Substances: Possibilities and Challenges].Fortschritte der Neurologie-Psychiatrie · 2017-07-01The fibrinolytic system: A new target for treatment of depression with psychedelics.Medical hypotheses · 2017-03-01A New Spectrophotometric Method for the Determination of Psilocin and PsilocybinInternational Journal of Analytical and Applied Chemistry · 2017-01-01Research on Acute Toxicity and the Behavioral Effects of Methanolic Extract from Psilocybin Mushrooms and Psilocin in MiceToxins · 2015-03-27Pholiotina cyanopus, a rare fungus producingpsychoactive tryptaminesOpen Life Sciences · 2014-11-19Effects of Psilocybe argentipes on marble-burying behavior in mice.Bioscience, biotechnology, and biochemistry · 2009-08-01Agonist-trafficking and hallucinogens.Current medicinal chemistry · 2009-01-01Chemical interactions with pyramidal neurons in layer 5 of the cerebral cortex: control of pain and anxiety.Current medicinal chemistry · 2009-01-01Psilocybin-induced stimulus control in the rat.Pharmacology, biochemistry, and behavior · 2007-10-01SAR of psilocybin analogs: discovery of a selective 5-HT2C agonist.Bioorganic & medicinal chemistry letters · 2005-10-15Effect of ring fluorination on the pharmacology of hallucinogenic tryptamines.Journal of medicinal chemistry · 2000-11-30Further studies on oxygenated tryptamines with LSD-like activity incorporating a chiral pyrrolidine moiety into the side chain.Journal of medicinal chemistry · 1999-10-07Psilocin analogs. III. Synthesis of 5-methoxy- and 5-hydroxy-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indolesJournal of Heterocyclic Chemistry · 1982-07-01Comparison of solution conformational preferences for the hallucinogens bufotenin and psilocin using 360-MHz proton NMR spectroscopyJournal of Medicinal Chemistry · 1981-02-01Psilocin analogs II. Synthesis of 3-[2-(dialkylamino)ethyl]-, 3-[2-(N-methyl-N-alkylamino)ethyl]-, and 3-[2-(cycloalkylamino)ethyl]indol-4-olsJournal of Heterocyclic Chemistry · 1981-01-01Psilocybin: biphasic dose-response effects on the acoustic startle reflex in the rat.Pharmacology, biochemistry, and behavior · 1977-04-01Psilocin analogs. 1. Synthesis of 3-[2-(dialkylamino)ethyl] -and 3-[2-(cycloalkylamino)ethyl] indol-4-olsJournal of Heterocyclic Chemistry · 1977-02-01Comparison of the discriminative stimulus properties of delta9-THC and psilocybin in rats.Pharmacology, biochemistry, and behavior · 1975-01-01Benzo[b]thiophene derivatives. XXI. On the proof of structure of the sulfur isostere of psilocinJournal of Heterocyclic Chemistry · 1973-12-01ChemInform Abstract: CHLORIERTE 2-HYDROXY- UND2-METHOXY-PHENOXYAETHYLAMINE, ANALOGA VON PSILOCYBINChemischer Informationsdienst Organische Chemie · 1971-03-09ChemInform Abstract: INDOLE 22. MITT. INDOLSYNTH., ANWENDUNG AUF PSILOCINChemischer Informationsdienst. Organische Chemie · 1970-12-21ChemInform Abstract: AUFTRETEN DES PSYCHOTOMIMETISCHEN AGENS PSILOCYBIN IN DEM AUSTRALISCHEN BLAETTERPILZ PSILOCYBE SUBAERUGINOSAChemischer Informationsdienst Organische Chemie · 1970-07-21The occurrence of the psychotomimetic agent psilocybin in an Australian agaric, Psilocybe subaeruginosaAustralian Journal of Chemistry · 1970-04-01Biosynthesis of psilocybin. II. Incorporation of labelled tryptamine derivatives.Acta chemica Scandinavica · 1968-01-01ANALOGUES OF PSILOCIN AND LYSERGIC ACID DIETHYLAMIDE I. CHLORO, NITRO, AND AMINO DERIVATIVES OF3-SUBSTITUTED INDOLESCanadian Journal of Chemistry · 1963-09-30Zur Identifizierung von Psilocin, einem psychotropen Inhaltstoff mexikanischer Rauschpilze der Gattungen Psilocybe und StrophariaAnalytical and Bioanalytical Chemistry · 1960-01-01